{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:59:52Z","timestamp":1790258392778,"version":"4.1.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T00:00:00Z","timestamp":1677715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["63631 0011"],"award-info":[{"award-number":["63631 0011"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.schres.2023.02.024","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T23:05:05Z","timestamp":1677539105000},"page":"133-142","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Systematic review and meta-analysis on predictors of prognosis in patients with schizophrenia spectrum disorders: An overview of current evidence and a call for prospective research and open access to datasets"],"prefix":"10.1016","volume":"254","author":[{"given":"Violet","family":"van Dee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo G.","family":"Schnack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiepke","family":"Cahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1\u20133","key":"10.1016\/j.schres.2023.02.024_bb0005","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.schres.2012.05.007","article-title":"Risk factors for relapse following treatment for first episode psychosis: a systematic review and meta-analysis of longitudinal studies","volume":"139","author":"Alvarez-Jimenez","year":"2012","journal-title":"Schizophr. Res."},{"issue":"3","key":"10.1016\/j.schres.2023.02.024_bb0010","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1176\/appi.ajp.162.3.441","article-title":"Remission in schizophrenia: proposed criteria and rationale for consensus","volume":"162","author":"Andreasen","year":"2005","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.schres.2023.02.024_bb0015","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.schres.2020.06.026","article-title":"Relationships between psychiatric symptoms, functioning and personal recovery in psychosis","volume":"223","author":"Best","year":"2020","journal-title":"Schizophr. Res."},{"issue":"11","key":"10.1016\/j.schres.2023.02.024_bb0020","article-title":"Interventions for prodromal stage of psychosis","volume":"2019","author":"Bosnjak Kuharic","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"issue":"4","key":"10.1016\/j.schres.2023.02.024_bb0025","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1751-7893.2009.00148.x","article-title":"Review of the operational definition for first-episode psychosis","volume":"3","author":"Breitborde","year":"2009","journal-title":"Early Interv. Psychiatry"},{"issue":"5","key":"10.1016\/j.schres.2023.02.024_bb0030","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/nrn3475","article-title":"Power failure: why small sample size undermines the reliability of neuroscience","volume":"14","author":"Button","year":"2013","journal-title":"Nat. Rev. Neurosci."},{"issue":"4","key":"10.1016\/j.schres.2023.02.024_bb0035","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1093\/schbul\/sbx120","article-title":"Flourishing with psychosis: a prospective examination on the interactions between clinical, functional, and personal recovery processes on well-being among individuals with schizophrenia Spectrum disorders","volume":"44","author":"Chan","year":"2018","journal-title":"Schizophr. Bull."},{"issue":"1","key":"10.1016\/j.schres.2023.02.024_bb0040","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.schres.2015.11.025","article-title":"The readmission rate and medical cost of patients with schizophrenia after first hospitalization - a 10-year follow-up population-based study","volume":"170","author":"Chi","year":"2016","journal-title":"Schizophr. Res."},{"issue":"6","key":"10.1016\/j.schres.2023.02.024_bb0045","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1001\/jamapsychiatry.2018.0623","article-title":"Comparison of early intervention services vs treatment as usual for early-phase psychosis: a systematic review, meta-analysis, and meta-regression","volume":"75","author":"Correll","year":"2018","journal-title":"JAMA Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2023.02.024_bb0050","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1080\/17522439.2015.1053969","article-title":"Does childhood bullying lead to the development of psychotic symptoms? A meta-analysis and review of prospective studies","volume":"8","author":"Cunningham","year":"2016","journal-title":"Psychosis"},{"issue":"1","key":"10.1016\/j.schres.2023.02.024_bb0055","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s41537-021-00162-3","article-title":"Individualized prediction of three- and six-year outcomes of psychosis in a longitudinal multicenter study: a machine learning approach","volume":"7","author":"de Nijs","year":"2021","journal-title":"npj Schizophrenia"},{"key":"10.1016\/j.schres.2023.02.024_bb0060","series-title":"The Independent and Combined Influence of Schizophrenia Polygenic Risk Score and Heavy Cannabis Use on Risk for Psychotic Disorder: A Case-control Analysis From the EUGEI Study","first-page":"844803","author":"Di Forti","year":"2019"},{"issue":"2","key":"10.1016\/j.schres.2023.02.024_bb0065","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/schbul\/sbab114","article-title":"Overlap and mutual distinctions between clinical recovery and personal recovery in people with schizophrenia in a one-year study","volume":"48","author":"Dubreucq","year":"2022","journal-title":"Schizophr. Bull."},{"issue":"6","key":"10.1016\/j.schres.2023.02.024_bb0070","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1001\/archpsyc.1976.01770060086012","article-title":"The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance","volume":"33","author":"Endicott","year":"1976","journal-title":"Arch. Gen. Psychiatry"},{"issue":"3","key":"10.1016\/j.schres.2023.02.024_bb0075","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1001\/archgenpsychiatry.2011.1472","article-title":"Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk","volume":"69","author":"Fusar-Poli","year":"2012","journal-title":"Arch. Gen. Psychiatry"},{"issue":"7","key":"10.1016\/j.schres.2023.02.024_bb0080","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1001\/jamapsychiatry.2019.4779","article-title":"Prevention of psychosis: advances in detection, prognosis, and intervention","volume":"77","author":"Fusar-Poli","year":"2020","journal-title":"JAMA Psychiatry"},{"issue":"1\u20133","key":"10.1016\/j.schres.2023.02.024_bb0085","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.schres.2010.02.1073","article-title":"A systematic review of relapse measurement in randomized controlled trials of relapse prevention in first-episode psychosis","volume":"119","author":"Gleeson","year":"2010","journal-title":"Schizophr. Res."},{"issue":"3","key":"10.1016\/j.schres.2023.02.024_bb0090","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0033-3182(95)71666-8","article-title":"Global assessment of functioningA modified scale","volume":"36","author":"Hall","year":"1995","journal-title":"Psychosomatics"},{"issue":"2\u20133","key":"10.1016\/j.schres.2023.02.024_bb0095","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.schres.2013.04.022","article-title":"Assessment of everyday functioning in schizophrenia: implications for treatments aimed at negative symptoms","volume":"150","author":"Harvey","year":"2013","journal-title":"Schizophr. Res."},{"issue":"6","key":"10.1016\/j.schres.2023.02.024_bb0100","doi-asserted-by":"crossref","first-page":"427","DOI":"10.7326\/0003-4819-144-6-200603210-00010","article-title":"Evaluation of the quality of prognosis studies in systematic reviews","volume":"144","author":"Hayden","year":"2006","journal-title":"Ann. Intern. Med."},{"issue":"1","key":"10.1016\/j.schres.2023.02.024_bb0105","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/wps.20822","article-title":"The clinical significance of duration of untreated psychosis: an umbrella review and random-effects meta-analysis","volume":"20","author":"Howes","year":"2021","journal-title":"World Psychiatry"},{"issue":"6","key":"10.1016\/j.schres.2023.02.024_bb0110","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/eip.12412","article-title":"Age at onset and the outcomes of schizophrenia: a systematic review and meta-analysis","volume":"11","author":"Immonen","year":"2017","journal-title":"Early Interv. Psychiatry"},{"issue":"9","key":"10.1016\/j.schres.2023.02.024_bb0115","first-page":"798","article-title":"Making individual prognoses in psychiatry using neuroimaging and machine learning","volume":"3","author":"Janssen","year":"2018","journal-title":"Biol. Psychiatry Cogn. Neurosci. Neuroimaging"},{"key":"10.1016\/j.schres.2023.02.024_bb0120","doi-asserted-by":"crossref","first-page":"15067","DOI":"10.1038\/nrdp.2015.67","article-title":"Schizophrenia","volume":"1","author":"Kahn","year":"2015","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.schres.2023.02.024_bb0125","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jpsychires.2015.07.008","article-title":"Social cognition, social competence, negative symptoms and social outcomes: inter-relationships in people with schizophrenia","volume":"68","author":"Kalin","year":"2015","journal-title":"J. Psychiatr. Res."},{"issue":"10","key":"10.1016\/j.schres.2023.02.024_bb0130","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S2215-0366(16)30171-7","article-title":"Multisite prediction of 4-week and 52-week treatment outcomes in patients with first-episode psychosis: a machine learning approach","volume":"3","author":"Koutsouleris","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2023.02.024_bb0135","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1186\/s12888-018-1755-2","article-title":"Functional recovery in patients with schizophrenia: recommendations from a panel of experts","volume":"18","author":"Lahera","year":"2018","journal-title":"BMC Psychiatry"},{"issue":"6","key":"10.1016\/j.schres.2023.02.024_bb0140","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1192\/bjp.bp.117.201475","article-title":"Remission and recovery from first-episode psychosis in adults: systematic review and meta-analysis of long-term outcome studies","volume":"211","author":"Lally","year":"2017","journal-title":"Br. J. Psychiatry"},{"issue":"3","key":"10.1016\/j.schres.2023.02.024_bb0145","doi-asserted-by":"crossref","first-page":"393","DOI":"10.31887\/DCNS.2010.12.3\/mlambert","article-title":"Remission in schizophrenia: validity, frequency, predictors, and patients' perspective 5 years later","volume":"12","author":"Lambert","year":"2010","journal-title":"Dialogues Clin. Neurosci."},{"issue":"11","key":"10.1016\/j.schres.2023.02.024_bb0150","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.4088\/JCP.v67n1104","article-title":"Prediction of remission as a combination of symptomatic and functional remission and adequate subjective well-being in 2960 patients with schizophrenia","volume":"67","author":"Lambert","year":"2006","journal-title":"J Clin Psychiatry"},{"issue":"2\u20133","key":"10.1016\/j.schres.2023.02.024_bb0155","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.schres.2014.04.011","article-title":"Psychometric properties of the questionnaire about the process of recovery (QPR)","volume":"156","author":"Law","year":"2014","journal-title":"Schizophr. Res."},{"issue":"9896","key":"10.1016\/j.schres.2023.02.024_bb0160","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0140-6736(13)60733-3","article-title":"Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis","volume":"382","author":"Leucht","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.schres.2023.02.024_bb0165","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.jad.2020.04.056","article-title":"Prevalence of comorbid depression in schizophrenia: a meta-analysis of observational studies","volume":"273","author":"Li","year":"2020","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.schres.2023.02.024_bb0170","series-title":"CochraneHandbook for Systematic Reviews of Interventions version 6.2 (updated February 2021)","article-title":"Chapter 12: Synthesizing and presenting findings using other methods","author":"McKenzie","year":"2021"},{"key":"10.1016\/j.schres.2023.02.024_bb0175","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.neulet.2016.10.003","article-title":"Duration of untreated illness as a key to early intervention in schizophrenia: a review","volume":"669","author":"Murru","year":"2018","journal-title":"Neurosci. Lett."},{"issue":"7","key":"10.1016\/j.schres.2023.02.024_bb0180","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1111\/j.1469-7610.2005.01535.x","article-title":"Temperament, parenting, and depressive symptoms in a population sample of preadolescents","volume":"47","author":"Oldehinkel","year":"2006","journal-title":"J. Child Psychol. Psychiatry"},{"key":"10.1016\/j.schres.2023.02.024_bb0185","article-title":"A guide to systematic review and meta-analysis of prognostic factor studies","volume":"364","author":"Riley","year":"2019","journal-title":"BMJ"},{"issue":"Suppl. 2","key":"10.1016\/j.schres.2023.02.024_bb0190","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1093\/schbul\/sbr072","article-title":"Effectiveness of integrated psychological therapy (IPT) for schizophrenia patients: a research update","volume":"37","author":"Roder","year":"2011","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.schres.2023.02.024_bb0195","series-title":"Proceedings of the 21st International Conference on Evaluation and Assessment in Software Engineering","first-page":"118","article-title":"A machine learning approach for semi-automated search and selection in literature studies","author":"Ros","year":"2017"},{"issue":"2","key":"10.1016\/j.schres.2023.02.024_bb0200","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1093\/schbul\/sbaa120","article-title":"Implementing precision psychiatry: a systematic review of individualized prediction models for clinical practice","volume":"47","author":"Salazar de Pablo","year":"2021","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.schres.2023.02.024_bb0205","first-page":"1","article-title":"Genetic liability to schizophrenia is associated with exposure to traumatic events in childhood","author":"Sallis","year":"2020","journal-title":"Psychol. Med."},{"key":"10.1016\/j.schres.2023.02.024_bb0210","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.cpr.2017.09.007","article-title":"Predictors of functional recovery in first-episode psychosis: a systematic review and meta-analysis of longitudinal studies","volume":"58","author":"Santesteban-Echarri","year":"2017","journal-title":"Clin. Psychol. Rev."},{"issue":"MAR","key":"10.1016\/j.schres.2023.02.024_bb0215","article-title":"Detecting neuroimaging biomarkers for psychiatric disorders: sample size matters. Frontiers","volume":"7","author":"Schnack","year":"2016","journal-title":"Psychiatry"},{"issue":"11","key":"10.1016\/j.schres.2023.02.024_bb0220","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1001\/archpsyc.1983.01790100074010","article-title":"A children's global assessment scale (CGAS)","volume":"40","author":"Shaffer","year":"1983","journal-title":"Arch. Gen. Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2023.02.024_bb0225","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.schres.2015.03.033","article-title":"Determinants of different aspects of everyday outcome in schizophrenia: the roles of negative symptoms, cognition, and functional capacity","volume":"165","author":"Strassnig","year":"2015","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.schres.2023.02.024_bb0230","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1017\/S0954579417000141","article-title":"Insensitive parenting may accelerate the development of the amygdala-medial prefrontal cortex circuit","volume":"29","author":"Thijssen","year":"2017","journal-title":"Dev. Psychopathol."},{"issue":"3","key":"10.1016\/j.schres.2023.02.024_bb0235","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1093\/schbul\/sbx088","article-title":"The relationship between clinical and personal recovery in patients with schizophrenia Spectrum disorders: a systematic review and meta-analysis","volume":"44","author":"Van Eck","year":"2018","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.schres.2023.02.024_bb0240","doi-asserted-by":"crossref","DOI":"10.3389\/frma.2021.685591","article-title":"SYMBALS: a systematic review methodology blending active learning and snowballing","volume":"6","author":"van Haastrecht","year":"2021","journal-title":"Front. Res. Metr. Anal."},{"issue":"2","key":"10.1016\/j.schres.2023.02.024_bb0245","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1037\/prj0000356","article-title":"Conceptualizations, assessments, and implications of personal recovery in mental illness: a scoping review of systematic reviews and meta-analyses","volume":"42","author":"van Weeghel","year":"2019","journal-title":"Psychiatr Rehabil J"},{"issue":"Pt A","key":"10.1016\/j.schres.2023.02.024_bb0250","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.neuroimage.2017.06.061","article-title":"Cross-validation failure: small sample sizes lead to large error bars","volume":"180","author":"Varoquaux","year":"2018","journal-title":"NeuroImage"},{"key":"10.1016\/j.schres.2023.02.024_bb0255","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.schres.2019.12.001","article-title":"Negative symptoms predict high relapse rates and both predict less favorable functional outcome in first episode psychosis, independent of treatment strategy","volume":"216","author":"Wunderink","year":"2020","journal-title":"Schizophr. Res."}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996423000762?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996423000762?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:37:35Z","timestamp":1777581455000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996423000762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":51,"alternative-id":["S0920996423000762"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2023.02.024","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systematic review and meta-analysis on predictors of prognosis in patients with schizophrenia spectrum disorders: An overview of current evidence and a call for prospective research and open access to datasets","name":"articletitle","label":"Article Title"},{"value":"Schizophrenia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.schres.2023.02.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}