{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:56:57Z","timestamp":1791586617417,"version":"4.3.4"},"reference-count":113,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014013","name":"UK Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000764","name":"King's College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.schres.2025.03.027","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T06:59:06Z","timestamp":1743663546000},"page":"59-70","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Prevalence and associations of fatigue in psychosis: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"279","author":[{"given":"Kim","family":"Poole-Wright","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aakash","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"Gaughran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trudie","family":"Chalder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0005","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1186\/s12888-018-1856-y","article-title":"Patient preferences concerning the efficacy and side-effect profile of schizophrenia medications: a survey of patients living with schizophrenia","volume":"18","author":"Achtyes","year":"2018","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.schres.2025.03.027_bb0010","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.schres.2020.05.003","article-title":"Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways","volume":"222","author":"Almulla","year":"2020","journal-title":"Schizophr. Res."},{"issue":"5","key":"10.1016\/j.schres.2025.03.027_bb0015","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1017\/neu.2020.16","article-title":"High frequency of clinical conditions commonly associated with mitochondrial disorders in schizophrenia","volume":"32","author":"Alonso","year":"2020","journal-title":"Acta Neuropsychiatrica"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0020","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1755-7682-6-47","article-title":"Efficacy and tolerability of quetiapine versus haloperidol in first-episode schizophrenia: a randomized clinical trial","volume":"6","author":"Amr","year":"2013","journal-title":"Int. Arch. Med."},{"key":"10.1016\/j.schres.2025.03.027_bb0025","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1192\/S0007125000291496","article-title":"The scale for the assessment of negative symptoms (SANS): conceptual and theoretical foundations","volume":"155","author":"Andreasen","year":"1989","journal-title":"Br. J. Psychiatry"},{"issue":"S271","key":"10.1016\/j.schres.2025.03.027_bb0030","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1600-0447.1978.tb02357.x","article-title":"A comprehensive psychopathological rating scale","volume":"57","author":"Asberg","year":"1978","journal-title":"Acta Psychiatr. Scand."},{"issue":"6","key":"10.1016\/j.schres.2025.03.027_bb0035","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/01.jcp.0000185423.15891.02","article-title":"Sex differences in the subjective tolerability of antipsychotic drugs","volume":"25","author":"Barbui","year":"2005","journal-title":"J. Clin. Psychopharmacol."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0040","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0893-133X(95)00069-P","article-title":"Olanzapine versus placebo and haloperidol: acute phase results of the North American double-blind olanzapine trial","volume":"14","author":"Beasley","year":"1996","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0045","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3390\/ijerph17010118","article-title":"The effects of a Forest therapy programme on mental hospital patients with affective and psychotic disorders","volume":"17","author":"Bielinis","year":"2019","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0050","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/s41398-020-00960-w","article-title":"Disentangling fatigue from anhedonia: a scoping review","volume":"10","author":"Billones","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.schres.2025.03.027_bb0055","article-title":"Dissecting the fatigue experience: a scoping review of fatigue definitions, dimensions, and measures in non-oncologic medical conditions","volume":"15","author":"Billones","year":"2021","journal-title":"Brain Behav Immun Health"},{"issue":"5","key":"10.1016\/j.schres.2025.03.027_bb0060","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.eujim.2016.06.004","article-title":"Sleep disorders in patients with depression or schizophrenia: a randomized controlled trial using acupuncture treatment","volume":"8","author":"Bosch","year":"2016","journal-title":"Eur. J. Integr. Med."},{"issue":"7","key":"10.1016\/j.schres.2025.03.027_bb0065","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1001\/archpsyc.1993.01820190043005","article-title":"Effects of metabolic perturbation on plasma homovanillic acid in schizophrenia: relationship to prefrontal cortex volume","volume":"50","author":"Breier","year":"1993","journal-title":"Arch. Gen. Psychiatry"},{"issue":"4","key":"10.1016\/j.schres.2025.03.027_bb0070","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1080\/15402002.2013.801345","article-title":"Understanding mental and physical fatigue complaints in those with depression and insomnia","volume":"12","author":"Carney","year":"2014","journal-title":"Behav. Sleep Med."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0075","doi-asserted-by":"crossref","first-page":"S88","DOI":"10.1093\/schizbullopen\/sgac011","article-title":"Sleep in psychotic disorders: results from nationwide SUPER Finland study","volume":"3","author":"Cederl\u00f6f","year":"2022","journal-title":"Schizophrenia Bulletin Open"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0080","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s11126-012-9233-3","article-title":"Quality of life and adverse effects of olanzapine versus risperidone therapy in patients with schizophrenia","volume":"84","author":"Chaves","year":"2013","journal-title":"Psychiatry Q."},{"issue":"10","key":"10.1016\/j.schres.2025.03.027_bb0085","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1177\/070674379804301007","article-title":"Phase-IV multicentre clinical study of risperidone in the treatment of outpatients with schizophrenia","volume":"43","author":"Chouinard","year":"1998","journal-title":"Can. J. Psychiatry"},{"key":"10.1016\/j.schres.2025.03.027_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2023.105454","article-title":"An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs","volume":"155","author":"Chow","year":"2023","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0095","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/BF03168931","article-title":"Prevalence of fatigue in general practice","volume":"171","author":"Cullen","year":"2002","journal-title":"Ir. J. Med. Sci."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0100","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s11126-015-9385-z","article-title":"Quality of life and hormonal, biochemical, and anthropometric profile between olanzapine and risperidone users","volume":"87","author":"de Ara\u00fajo","year":"2016","journal-title":"Psychiatric quarterly"},{"issue":"24","key":"10.1016\/j.schres.2025.03.027_bb0105","doi-asserted-by":"crossref","first-page":"20737","DOI":"10.1007\/s12144-022-03145-4","article-title":"Cognitive effort in schizophrenia: Dissimilar effects on cardiovascular activity and subjective effort","volume":"42","author":"D\u00e9combe","year":"2023","journal-title":"Current Psychology (New Brunswick, N.J.)"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0110","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1017\/S1461145704004729","article-title":"The many faces of fatigue in major depressive disorder","volume":"8","author":"Demyttenaere","year":"2005","journal-title":"Int. J. Neuropsychopharmacol."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0115","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/BF02245748","article-title":"Double blind comparative study of remoxipride and haloperidol in acute schizophrenic patients","volume":"102","author":"Den Boer","year":"1990","journal-title":"Psychopharmacology"},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0120","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0022-3999(03)00371-4","article-title":"The assessment of fatigue","volume":"56","author":"Dittner","year":"2004","journal-title":"J. Psychosom. Res."},{"issue":"5","key":"10.1016\/j.schres.2025.03.027_bb0125","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.biopsych.2009.09.033","article-title":"A meta-analysis of cytokines in major depression","volume":"67","author":"Dowlati","year":"2010","journal-title":"Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.schres.2025.03.027_bb0130","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/da.22199","article-title":"Clinical relevance of fatigue as a residual symptom in major depressive disorder","volume":"31","author":"Fava","year":"2014","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.schres.2025.03.027_bb0135","article-title":"The role of inflammation in the treatment of schizophrenia","volume":"11","author":"Fond","year":"2020","journal-title":"Front. Psych."},{"issue":"5","key":"10.1016\/j.schres.2025.03.027_bb0140","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.jpsychores.2010.05.005","article-title":"Relations between sleep, fatigue, and health-related quality of life in individuals with insomnia","volume":"69","author":"Fortier-Brochu","year":"2010","journal-title":"J. Psychosom. Res."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0145","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1037\/h0034952","article-title":"Early subjective experience in schizophrenic episodes","volume":"82","author":"Freedman","year":"1973","journal-title":"J. Abnorm. Psychol."},{"issue":"12","key":"10.1016\/j.schres.2025.03.027_bb0150","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.4088\/JCP.08m04683","article-title":"Modafinil for clozapine-treated schizophrenia patients: a double-blind, placebo-controlled pilot trial","volume":"70","author":"Freudenreich","year":"2009","journal-title":"J. Clin. Psychiatry"},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090311","article-title":"The impact of individual depressive symptoms on impairment of psychosocial functioning","volume":"9","author":"Fried","year":"2014","journal-title":"PloS One"},{"issue":"Suppl(S1)","key":"10.1016\/j.schres.2025.03.027_bb0160","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF00442570","article-title":"Side effects of clozapine","volume":"99","author":"Gaertner","year":"1989","journal-title":"Psychopharmacology"},{"issue":"8","key":"10.1016\/j.schres.2025.03.027_bb0165","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-027070","article-title":"Prevalence and factors associated with fatigue in the Lausanne middle-aged population: a population-based, cross-sectional survey","volume":"9","author":"Galland-Decker","year":"2019","journal-title":"BMJ Open"},{"issue":"12","key":"10.1016\/j.schres.2025.03.027_bb0170","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1017\/S0033291715000562","article-title":"Cardiovascular risk factors and metabolic syndrome in people with established psychotic illnesses: baseline data from the IMPaCT randomized controlled trial","volume":"45","author":"Gardner-Sood","year":"2015","journal-title":"Psychol. Med."},{"issue":"5","key":"10.1016\/j.schres.2025.03.027_bb0175","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.comppsych.2008.02.007","article-title":"Depressive symptom profiles and severity patterns in outpatients with psychotic vs nonpsychotic major depression","volume":"49","author":"Gaudiano","year":"2008","journal-title":"Compr. Psychiatry"},{"issue":"3","key":"10.1016\/j.schres.2025.03.027_bb0180","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1080\/13651500601176963","article-title":"The \u201cSeroquel\u201d Outcomes Study (SOS): efficacy and tolerability of quetiapine in a long-term, naturalistic study of patients with schizophrenia","volume":"11","author":"Gibert","year":"2007","journal-title":"Int. J. Psychiatry Clin. Pract."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0185","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1176\/appi.neuropsych.18010011","article-title":"Depressive symptoms are associated with more negative functional outcomes than anxiety symptoms in persons with multiple sclerosis","volume":"31","author":"Gill","year":"2019","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"issue":"3","key":"10.1016\/j.schres.2025.03.027_bb0190","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/sj.npp.1301444","article-title":"A placebo-controlled add-on trial of the Ampakine, CX516, for cognitive deficits in schizophrenia","volume":"33","author":"Goff","year":"2008","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"10.1016\/j.schres.2025.03.027_bb0195","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2165\/11530230-000000000-00000","article-title":"Defining and measuring functional recovery from depression","volume":"24","author":"Greer","year":"2010","journal-title":"CNS Drugs"},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0200","first-page":"87","article-title":"Common side effects and metabolic syndrome due to clozapine: relationship with the clinical variables and disability","volume":"32","author":"G\u00fcrcan","year":"2021","journal-title":"Turk Psikiyatri Derg."},{"issue":"8","key":"10.1016\/j.schres.2025.03.027_bb0205","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1176\/appi.ajp.2015.15010093","article-title":"A randomized trial to assess the efficacy and safety of ABT-126, a selective alpha7 nicotinic acetylcholine receptor agonist, in the treatment of cognitive impairment in schizophrenia","volume":"173","author":"Haig","year":"2016","journal-title":"Am. J. Psychiatry"},{"issue":"4","key":"10.1016\/j.schres.2025.03.027_bb0210","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1097\/YIC.0b013e328354dcda","article-title":"Sertindole in the long-term treatment of schizophrenia","volume":"27","author":"Hale","year":"2012","journal-title":"Int. Clin. Psychopharmacol."},{"issue":"8","key":"10.1016\/j.schres.2025.03.027_bb0215","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0005-7967(01)00061-4","article-title":"A cognitive model of insomnia","volume":"40","author":"Harvey","year":"2002","journal-title":"Behav. Res. Ther."},{"key":"10.1016\/j.schres.2025.03.027_bb0220","first-page":"148","article-title":"High aerobic intensity training and psychological states in patients with depression or schizophrenia","volume":"5","author":"Heggelund","year":"2014","journal-title":"Front. Psych."},{"issue":"4","key":"10.1016\/j.schres.2025.03.027_bb0225","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/j.1440-1819.1993.tb01824.x","article-title":"Prodromal symptoms of relapse in schizophrenic outpatients: retrospective and prospective study","volume":"47","author":"Henmi","year":"1993","journal-title":"Psychiatry Clin. Neurosci."},{"issue":"7414","key":"10.1016\/j.schres.2025.03.027_bb0230","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0235","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-244X-5-13","article-title":"Quality of sleep in patients with schizophrenia is associated with quality of life and coping","volume":"5","author":"Hofstetter","year":"2005","journal-title":"BMC Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0240","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/j.1749-6632.1985.tb29947.x","article-title":"The effects of cholecystokinin-like peptides in schizophrenics and normal human subjects","volume":"448","author":"Hommer","year":"1985","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0245","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/inm.12547","article-title":"Physical health status of older adults with severe mental illness: The PHiSMI-E cohort study","volume":"28","author":"Houben","year":"2019","journal-title":"Int. J. Ment. Health Nurs."},{"issue":"10202","key":"10.1016\/j.schres.2025.03.027_bb0250","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0140-6736(19)31135-3","article-title":"Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis","volume":"394","author":"Huhn","year":"2019","journal-title":"The Lancet"},{"issue":"12","key":"10.1016\/j.schres.2025.03.027_bb0255","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0243437","article-title":"The side effect profile of clozapine in real world data of three large mental health hospitals","volume":"15","author":"Iqbal","year":"2020","journal-title":"PloS One"},{"issue":"7","key":"10.1016\/j.schres.2025.03.027_bb0260","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/pcn.13221","article-title":"Efficacy and safety of lurasidone in acutely psychotic patients with schizophrenia: a 6-week, randomized, double-blind, placebo-controlled study","volume":"75","author":"Iyo","year":"2021","journal-title":"Psychiatry Clin. Neurosci."},{"issue":"10159","key":"10.1016\/j.schres.2025.03.027_bb0265","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","author":"James","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.schres.2025.03.027_bb0270","series-title":"JBI Critical Appraisal Tools","volume":"vol. 2023","year":"2022"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0275","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.npbr.2015.12.032","article-title":"Neuroinflammation in patients with psychosis: first results of a placebo controlled study with 8 gram valaciclovir daily","volume":"22","author":"Jonker","year":"2016","journal-title":"Neurol. Psychiatry Brain Res."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0280","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s002130050755","article-title":"Ziprasidone 40 and 120 mg\/day in the acute exacerbation of schizophrenia and schizoaffective disorder: a 4-week placebo-controlled trial","volume":"140","author":"Keck","year":"1998","journal-title":"Psychopharmacology"},{"issue":"3","key":"10.1016\/j.schres.2025.03.027_bb0285","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.ajp.2012.10.007","article-title":"Efficacy and tolerability of clozapine in Japanese patients with treatment-resistant schizophrenia: results from a 12-week, flexible dose study using raters masked to antipsychotic choice","volume":"6","author":"Kishi","year":"2013","journal-title":"Asian J. Psychiatr."},{"issue":"1 Suppl 1","key":"10.1016\/j.schres.2025.03.027_bb0290","doi-asserted-by":"crossref","first-page":"45S","DOI":"10.1097\/00004714-199502001-00008","article-title":"Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia","volume":"15","author":"Klieser","year":"1995","journal-title":"J. Clin. Psychopharmacol."},{"issue":"4","key":"10.1016\/j.schres.2025.03.027_bb0295","doi-asserted-by":"crossref","first-page":"534","DOI":"10.3390\/jcm8040534","article-title":"Clinical characteristics of obstructive sleep apnea in psychiatric disease","volume":"8","author":"Knechtle","year":"2019","journal-title":"J. Clin. Med."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0300","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1192\/bjp.154.2.207","article-title":"Negative and depressive symptoms in schizophrenia","volume":"154","author":"Kulhara","year":"1989","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.schres.2025.03.027_bb0305","article-title":"Preliminary evidence that fatigue contributes to anhedonia in stable individuals diagnosed with schizophrenia","volume":"14","author":"Laraki","year":"2023","journal-title":"Front. Psych."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0310","first-page":"58","article-title":"Psychometric properties of the Fatigue Catastrophizing Scale in a general population and its clinical utility in schizophrenia and breast cancer patients","volume":"12","author":"Laraki","year":"2024","journal-title":"Fatigue (Abingdon, Eng.)"},{"issue":"S358","key":"10.1016\/j.schres.2025.03.027_bb0315","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1600-0447.1990.tb05303.x","article-title":"A double-blind multicentre study comparing remoxipride, two and three times daily, with haloperidol in schizophrenia","volume":"82","author":"Laux","year":"1990","journal-title":"Acta Psychiatr. Scand."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0320","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1348\/135910703762879237","article-title":"How sleep is related to fatigue","volume":"8","author":"Lavidor","year":"2003","journal-title":"Br. J. Health Psychol."},{"issue":"3","key":"10.1016\/j.schres.2025.03.027_bb0325","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/bjc.12356","article-title":"The relationship between repetitive negative thinking, sleep disturbance, and subjective fatigue in women with Generalized Anxiety Disorder","volume":"61","author":"Leung","year":"2022","journal-title":"Br. J. Clin. Psychol."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0330","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/s41398-022-02045-2","article-title":"Suicidality in clinically stable bipolar disorder and schizophrenia patients during the COVID-19 pandemic","volume":"12","author":"Li","year":"2022","journal-title":"Transl. Psychiatry"},{"issue":"8","key":"10.1016\/j.schres.2025.03.027_bb0335","first-page":"e465","article-title":"Psychosocial diagnoses occurring after patients present with fatigue","volume":"62","author":"MacKean","year":"2016","journal-title":"Can. Fam. Physician"},{"issue":"154","key":"10.1016\/j.schres.2025.03.027_bb0340","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/s12891-016-1011-1","article-title":"Are depression and anxiety associated with disease activity in rheumatoid arthritis? A prospective study","volume":"17","author":"Matcham","year":"2016","journal-title":"BMC Musculoskeletal Disorders"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0345","doi-asserted-by":"crossref","DOI":"10.1093\/schizbullopen\/sgab046","article-title":"Patient preferences for antipsychotic drug side effects: a discrete choice experiment","volume":"2","author":"McCrone","year":"2021","journal-title":"Schizophrenia Bulletin Open"},{"issue":"3","key":"10.1016\/j.schres.2025.03.027_bb0350","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.psc.2007.04.007","article-title":"Epidemiology of schizophrenia: review of findings and myths","volume":"30","author":"Messias","year":"2007","journal-title":"Psychiatr. Clin. N. Am."},{"key":"10.1016\/j.schres.2025.03.027_bb0355","series-title":"Preferred Reporting Items for Systematic Reviews and Meta-analyses: The PRISMA Statement","volume":"vol. 6","author":"Moher","year":"2009"},{"issue":"4","key":"10.1016\/j.schres.2025.03.027_bb0360","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A new depression scale designed to be sensitive to change","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br. J. Psychiatry"},{"issue":"3","key":"10.1016\/j.schres.2025.03.027_bb0365","doi-asserted-by":"crossref","first-page":"901","DOI":"10.3390\/jcm12030901","article-title":"Correlation of health-related quality of life with negative symptoms assessed with the Self-Evaluation of Negative Symptoms Scale (SNS) and cognitive deficits in schizophrenia: a cross-sectional study in routine psychiatric care","volume":"12","author":"Montvidas","year":"2023","journal-title":"J. Clin. Med."},{"issue":"4","key":"10.1016\/j.schres.2025.03.027_bb0370","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1080\/09638237.2017.1370637","article-title":"The least worst option: user experiences of antipsychotic medication and lack of involvement in medication decisions in a UK community sample","volume":"27","author":"Morant","year":"2018","journal-title":"J. Ment. Health"},{"issue":"12","key":"10.1016\/j.schres.2025.03.027_bb0375","doi-asserted-by":"crossref","first-page":"e1610","DOI":"10.4088\/JCP.15m10185","article-title":"Adjunctive taurine in first-episode psychosis: a phase 2, double-blind, randomized, placebo-controlled study","volume":"77","author":"O\u2019Donnell","year":"2016","journal-title":"Journal of Clinical Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0380","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan-a web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst. Rev."},{"key":"10.1016\/j.schres.2025.03.027_bb0385","series-title":"The Brief Psychiatric Rating Scale","first-page":"799","volume":"vol. 10","author":"Overall","year":"1962"},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0390","doi-asserted-by":"crossref","first-page":"153","DOI":"10.4103\/0253-7176.92067","article-title":"Analysis of adverse drug reactions of atypical antipsychotic drugs in psychiatry OPD","volume":"33","author":"Piparva","year":"2011","journal-title":"Indian J. Psychol. Med."},{"key":"10.1016\/j.schres.2025.03.027_bb0395","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.schres.2021.06.032","article-title":"Fatigue in psychosis","volume":"243","author":"Poole-Wright","year":"2022","journal-title":"Schizophr. Res."},{"issue":"10","key":"10.1016\/j.schres.2025.03.027_bb0400","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1185\/03007995.2013.821973","article-title":"Safety and tolerability of once monthly aripiprazole treatment initiation in adults with schizophrenia stabilized on selected atypical oral antipsychotics other than aripiprazole","volume":"29","author":"Potkin","year":"2013","journal-title":"Curr. Med. Res. Opin."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0405","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1186\/s13063-020-04606-6","article-title":"Assessment of the efficacy of a fatigue management therapy in schizophrenia: study protocol for a randomized, controlled multi-centered study (ENERGY)","volume":"21","author":"Raffard","year":"2020","journal-title":"Trials"},{"issue":"7","key":"10.1016\/j.schres.2025.03.027_bb0410","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.pnpbp.2007.06.008","article-title":"Effectiveness, safety, and tolerability of ziprasidone for treating schizophrenia patients undergoing usual care: a 12-month, open-label, flexible dose, naturalistic observational trial","volume":"31","author":"Ratner","year":"2007","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0415","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1093\/schbul\/sby129","article-title":"Sleep disorders in early psychosis: incidence, severity, and association with clinical symptoms","volume":"45","author":"Reeve","year":"2019","journal-title":"Schizophr. Bull."},{"issue":"386","key":"10.1016\/j.schres.2025.03.027_bb0420","first-page":"413","article-title":"Patients who consult with tiredness: frequency of consultation, perceived causes of tiredness and its association with psychological distress","volume":"44","author":"Ridsdale","year":"1994","journal-title":"Br. J. Gen. Pract."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0425","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/occmed\/kqi015","article-title":"Treatments for chronic fatigue syndrome","volume":"55","author":"Rimes","year":"2005","journal-title":"Occup. Med."},{"issue":"5","key":"10.1016\/j.schres.2025.03.027_bb0430","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.scispo.2020.03.005","article-title":"Physical activity for patients with severe mental illness: preferences, barriers and perceptions of counselling","volume":"35","author":"Romain","year":"2020","journal-title":"Science & Sports"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0435","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/00002826-200401000-00011","article-title":"Benefits of adjunct modafinil in an open-label, pilot study in patients with schizophrenia","volume":"27","author":"Rosenthal","year":"2004","journal-title":"Clin. Neuropharmacol."},{"key":"10.1016\/j.schres.2025.03.027_bb0505","series-title":"RStudio: Integrated Development Environment for R","volume":"vol. 1.3.1073","author":"RStudio Team","year":"2020"},{"issue":"6","key":"10.1016\/j.schres.2025.03.027_bb0475","doi-asserted-by":"crossref","first-page":"367","DOI":"10.3109\/08039489209167892","article-title":"Social conditions of first-admittance schizophrenics compared with those of the general population","volume":"46","author":"S\u2205rensen","year":"1992","journal-title":"Nord. J. Psychiatry"},{"issue":"0","key":"10.1016\/j.schres.2025.03.027_bb0440","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5455\/annalsmedres.2018.12.275","article-title":"A comparison of sleep, fatigue and quality of life of healthy and schizophrenic individuals","author":"Sahan","year":"2019","journal-title":"Annals of Medical Research"},{"key":"10.1016\/j.schres.2025.03.027_bb0445","first-page":"1785","article-title":"A cross-sectional study to assess the adverse effect profile of second generation antipsychotics: risperidone, olanzapine and quetiapine","author":"Scandashree","year":"2016","journal-title":"International Journal of Basic and Clinical Pharmacology"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0450","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13643-020-1274-3","article-title":"Psychotropic medication non-adherence and its associated factors among patients with major psychiatric disorders: a systematic review and meta-analysis","volume":"9","author":"Semahegn","year":"2020","journal-title":"Syst. Rev."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0455","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.psychres.2003.12.025","article-title":"Depressive syndrome in major psychoses: a study on 1351 subjects","volume":"127","author":"Serretti","year":"2004","journal-title":"Psychiatry Res."},{"issue":"07","key":"10.1016\/j.schres.2025.03.027_bb0460","doi-asserted-by":"crossref","first-page":"839","DOI":"10.4088\/JCP.v66n0705","article-title":"Double-blind, placebo-controlled study of modafinil for fatigue and cognition in schizophrenia patients treated with psychotropic medications","volume":"66","author":"Sevy","year":"2005","journal-title":"J. Clin. Psychiatry"},{"issue":"11","key":"10.1016\/j.schres.2025.03.027_bb0465","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1002\/mds.27461","article-title":"Fatigue in Parkinson\u2019s disease: a systematic review and meta-analysis","volume":"33","author":"Siciliano","year":"2018","journal-title":"Mov. Disord."},{"key":"10.1016\/j.schres.2025.03.027_bb0470","doi-asserted-by":"crossref","first-page":"25","DOI":"10.18203\/2349-3933.ijam20151483","article-title":"Factors affecting adherence in patients with schizophrenia","author":"Siddiqui","year":"2016","journal-title":"International Journal of Advances in Medicine"},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0480","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2165\/00044011-199917010-00006","article-title":"A bio-equivalence study of brand and generic clozapine in patients with schizophrenia. Pharmacokinetic and tolerability findings","volume":"17","author":"Sramek","year":"1999","journal-title":"Clin. Drug Investig."},{"issue":"7304","key":"10.1016\/j.schres.2025.03.027_bb0485","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1136\/bmj.323.7304.101","article-title":"Systematic reviews in health care: investigating and dealing with publication and other biases in meta-analysis","volume":"323","author":"Sterne","year":"2001","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.schres.2025.03.027_bb0490","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/wps.20567","article-title":"Management of common adverse effects of antipsychotic medications","volume":"17","author":"Stroup","year":"2018","journal-title":"World Psychiatry"},{"key":"10.1016\/j.schres.2025.03.027_bb5000","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.schres.2017.06.025","article-title":"Physical activity correlates among people with psychosis: Data from 47 low and middle-income countries","volume":"193","author":"Stubbs","year":"2018","journal-title":"Schizophr. Res."},{"issue":"11","key":"10.1016\/j.schres.2025.03.027_bb0495","article-title":"Physical activity, sleep-related behaviors and severity of symptoms in schizophrenia","volume":"294","author":"Taliercio","year":"2020","journal-title":"Psychiatry Res."},{"issue":"1","key":"10.1016\/j.schres.2025.03.027_bb0500","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.schres.2013.05.028","article-title":"Definition and description of schizophrenia in the DSM-5","volume":"150","author":"Tandon","year":"2013","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0510","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00127-019-01819-2","article-title":"Experiences of taking neuroleptic medication and impacts on symptoms, sense of self and agency: a systematic review and thematic synthesis of qualitative data","volume":"55","author":"Thompson","year":"2020","journal-title":"Social Psychiatry and Psychiatric Epidemiology: The International Journal for Research in Social and Genetic Epidemiology and Mental Health Services"},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0515","article-title":"Depression and schizophrenia: cause, consequence or trans-diagnostic issue?","volume":"43","author":"Upthegrove","year":"2016","journal-title":"Schizophr. Bull."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0520","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1600-0447.1993.tb03340.x","article-title":"A long-term study of remoxipride in chronic schizophrenic patients","volume":"87","author":"Vartiainen","year":"1993","journal-title":"Acta Psychiatr. Scand."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb5005","first-page":"181","article-title":"The patient experience of sleep problems and their treatment in the context of current delusions and hallucinations","volume":"89","author":"Waite","year":"2016","journal-title":"Psychol.: Pres. Pract."},{"key":"10.1016\/j.schres.2025.03.027_bb0525","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.schres.2019.11.014","article-title":"Sleep and schizophrenia: from epiphenomenon to treatable causal target","volume":"221","author":"Waite","year":"2020","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.schres.2025.03.027_bb0530","first-page":"581","article-title":"Cancer-related fatigue and biochemical parameters among cancer patients with different stages of sarcopenia","volume":"28","author":"Wang","year":"2020","journal-title":"Support. Care Cancer"},{"issue":"5","key":"10.1016\/j.schres.2025.03.027_bb0535","first-page":"003","article-title":"Clinical decision path for identifying recurrent falls in late middle-aged and older patients with chronic schizophrenia","volume":"29","author":"Wang","year":"2021","journal-title":"J. Nurs. Res."},{"issue":"1\u20133","key":"10.1016\/j.schres.2025.03.027_bb0540","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.schres.2012.05.013","article-title":"Effects of polypharmacy on sleep in psychiatric inpatients","volume":"139","author":"Waters","year":"2012","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2025.03.027_bb0545","article-title":"Sleep, fatigue, and functional health in psychotic patients","volume":"2013","author":"Waters","year":"2013","journal-title":"Schizophr. Res. Treat."},{"key":"10.1016\/j.schres.2025.03.027_bb0550","series-title":"The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Non-randomized Studies in Meta-analyses","author":"Wells","year":"2009"},{"key":"10.1016\/j.schres.2025.03.027_bb0555","doi-asserted-by":"crossref","first-page":"1192121","DOI":"10.3389\/fpubh.2023.1192121","article-title":"The demographic features of fatigue in the general population worldwide: a systematic review and meta-analysis","volume":"11","author":"Yoon","year":"2023","journal-title":"Front. Public Health"}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996425000921?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996425000921?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T04:39:01Z","timestamp":1762317541000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996425000921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":113,"alternative-id":["S0920996425000921"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2025.03.027","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence and associations of fatigue in psychosis: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Schizophrenia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.schres.2025.03.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}