{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T05:59:08Z","timestamp":1779343148328,"version":"3.51.4"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018696","name":"HORIZON EUROPE Health","doi-asserted-by":"publisher","award":["101057182"],"award-info":[{"award-number":["101057182"]}],"id":[{"id":"10.13039\/100018696","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["848041003"],"award-info":[{"award-number":["848041003"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["636340001"],"award-info":[{"award-number":["636340001"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Schizophrenia Research"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.schres.2025.09.023","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T22:55:31Z","timestamp":1759791331000},"page":"223-231","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Association between the exposome score for schizophrenia and functioning in remitted first-episode psychosis: results from the HAMLETT study"],"prefix":"10.1016","volume":"285","author":[{"given":"Sterre","family":"Kamphuis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Arias-Magnasco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiral","family":"Gangadin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marieke","family":"Begemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Wijnen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wim","family":"Veling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lieuwe","family":"de Haan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Sommer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"van Os","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Roberto","family":"Bakker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinan","family":"G\u00fcl\u00f6ks\u00fcz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.schres.2025.09.023_bb0005","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/s12888-016-0827-4","article-title":"A history of childhood trauma is associated with slower improvement rates: findings from a one-year follow-up study of patients with a first-episode psychosis","volume":"16","author":"Aas","year":"2016","journal-title":"BMC Psychiatry"},{"issue":"5","key":"10.1016\/j.schres.2025.09.023_bb0010","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s40263-016-0331-x","article-title":"Beyond clinical remission in first episode psychosis: thoughts on antipsychotic maintenance vs. guided discontinuation in the functional recovery era","volume":"30","author":"Alvarez-Jimenez","year":"2016","journal-title":"CNS Drugs"},{"key":"10.1016\/j.schres.2025.09.023_bb0015","series-title":"Diagnostic and statistical manual of mental disorders DSM-5","author":"American Psychiatric Association","year":"2013"},{"issue":"8","key":"10.1016\/j.schres.2025.09.023_bb0020","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1001\/archpsyc.1992.01820080023004","article-title":"The comprehensive assessment of symptoms and history (CASH): an instrument for assessing diagnosis and psychopathology","volume":"49","author":"Andreasen","year":"1992","journal-title":"Arch. Gen. Psychiatry"},{"issue":"9","key":"10.1016\/j.schres.2025.09.023_bb0025","first-page":"1322","article-title":"Missing data in clinical research: a tutorial on multiple imputation","volume":"37","author":"Austin","year":"2021","journal-title":"Can. J. Cardiol."},{"issue":"1","key":"10.1016\/j.schres.2025.09.023_bb0030","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/s13063-019-3822-5","article-title":"To continue or not to continue? Antipsychotic medication maintenance versus dose-reduction\/discontinuation in first episode psychosis: HAMLETT, a pragmatic multicenter single-blind randomized controlled trial","volume":"21","author":"Begemann","year":"2020","journal-title":"Trials"},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0035","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0145-2134(02)00541-0","article-title":"Development and validation of a brief screening version of the Childhood Trauma Questionnaire","volume":"27","author":"Bernstein","year":"2003","journal-title":"Child Abuse Negl."},{"key":"10.1016\/j.schres.2025.09.023_bb0040","doi-asserted-by":"crossref","DOI":"10.18637\/jss.v045.i03","article-title":"MICE: multivariate imputation by chained equations in R","volume":"45","author":"Buuren","year":"2011","journal-title":"J. Stat. Softw."},{"issue":"1","key":"10.1016\/j.schres.2025.09.023_bb0045","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1017\/ipm.2014.74","article-title":"Childhood trauma and functional disability in psychosis, bipolar disorder and borderline personality disorder: a review of the literature","volume":"32","author":"Cotter","year":"2015","journal-title":"Ir. J. Psychol. Med."},{"key":"10.1016\/j.schres.2025.09.023_bb0050","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.schres.2022.12.016","article-title":"Systematic review and meta-analysis: season of birth and schizophrenia risk","volume":"252","author":"Coury","year":"2023","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.schres.2025.09.023_bb0055","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.schres.2025.05.009","article-title":"Minimum data standards for schizophrenia and the EnvironmenT (MINDSET) research harmonization exercise","volume":"281","author":"Crossley","year":"2025","journal-title":"Schizophr. Res."},{"issue":"6","key":"10.1016\/j.schres.2025.09.023_bb0060","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1001\/archpsyc.1976.01770060086012","article-title":"The global assessment scale: a procedure for measuring overall severity of psychiatric disturbance","volume":"33","author":"Endicott","year":"1976","journal-title":"Arch. Gen. Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2025.09.023_bb0065","doi-asserted-by":"crossref","DOI":"10.1192\/j.eurpsy.2021.19","article-title":"Examining the association between exposome score for schizophrenia and functioning in schizophrenia, siblings, and healthy controls: results from the EUGEI study","volume":"64","author":"Erzin","year":"2021","journal-title":"Eur. Psychiatry"},{"issue":"6","key":"10.1016\/j.schres.2025.09.023_bb0070","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1017\/S0033291721004542","article-title":"Association between exposome score for schizophrenia and functioning in first-episode psychosis: results from the Athens first-episode psychosis research study","volume":"53","author":"Erzin","year":"2023","journal-title":"Psychol. Med."},{"issue":"5","key":"10.1016\/j.schres.2025.09.023_bb0075","doi-asserted-by":"crossref","first-page":"632","DOI":"10.4088\/JCP.11m07069","article-title":"Continued cannabis use and outcome in first-episode psychosis: data from a randomized, open-label, controlled trial","volume":"73","author":"Faber","year":"2012","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.schres.2025.09.023_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2023.115184","article-title":"Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: results from the EUGEI study","volume":"323","author":"Fusar-Poli","year":"2023","journal-title":"Psychiatry Res."},{"issue":"1","key":"10.1016\/j.schres.2025.09.023_bb0085","first-page":"1","article-title":"Relative importance for linear regression in R: the package relaimpo","volume":"17","author":"Groemping","year":"2006","journal-title":"J. Stat. Softw."},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0090","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1017\/S0033291717001775","article-title":"The slow death of the concept of schizophrenia and the painful birth of the psychosis spectrum","volume":"48","author":"Guloksuz","year":"2018","journal-title":"Psychol. Med."},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0095","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/wps.20629","article-title":"Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study","volume":"18","author":"Guloksuz","year":"2019","journal-title":"World Psychiatry"},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0100","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/wps.20755","article-title":"Association of preceding psychosis risk states and non-psychotic mental disorders with incidence of clinical psychosis in the general population: a prospective study in the NEMESIS-2 cohort","volume":"19","author":"Guloksuz","year":"2020","journal-title":"World Psychiatry"},{"key":"10.1016\/j.schres.2025.09.023_bb0105","doi-asserted-by":"crossref","DOI":"10.62186\/001c.125154","article-title":"Determining a meaningful R-squared value in clinical medicine","author":"Gupta","year":"2024","journal-title":"Acad. Med. Surg."},{"issue":"5","key":"10.1016\/j.schres.2025.09.023_bb0110","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S2215-0366(18)30090-7","article-title":"Long-term effects of discontinuation from antipsychotic maintenance following first-episode schizophrenia and related disorders: a 10 year follow-up of a randomised, double-blind trial","volume":"5","author":"Hui","year":"2018","journal-title":"Lancet Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2025.09.023_bb0115","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1017\/S1138741600004704","article-title":"The long-term effects of coping strategy use in victims of bullying","volume":"7","author":"Hunter","year":"2004","journal-title":"Span. J. Psychol."},{"issue":"4","key":"10.1016\/j.schres.2025.09.023_bb0120","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/j.1751-7893.2011.00289.x","article-title":"An examination of patient-identified goals for treatment in a first-episode programme in Chennai","volume":"5","author":"Iyer","year":"2011","journal-title":"India. Early Interv. Psychiatry"},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0125","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr. Bull."},{"issue":"10","key":"10.1016\/j.schres.2025.09.023_bb0130","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S2215-0366(16)30171-7","article-title":"Multisite prediction of 4-week and 52-week treatment outcomes in patients with first-episode psychosis: a machine learning approach","volume":"3","author":"Koutsouleris","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"11","key":"10.1016\/j.schres.2025.09.023_bb0135","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1001\/jamapsychiatry.2018.2165","article-title":"Prediction models of functional outcomes for individuals in the clinical high-risk state for psychosis or with recent-onset depression: a multimodal, multisite machine learning analysis","volume":"75","author":"Koutsouleris","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.schres.2025.09.023_bb0140","doi-asserted-by":"crossref","DOI":"10.1093\/schbul\/sbae219","article-title":"Evaluating the exposome score for schizophrenia in a transdiagnostic psychosis cohort: associations with psychosis risk, symptom severity, and personality traits","author":"Kromenacker","year":"2025","journal-title":"Schizophr. Bull."},{"issue":"6","key":"10.1016\/j.schres.2025.09.023_bb0145","doi-asserted-by":"crossref","first-page":"e261","DOI":"10.1016\/S2589-7500(19)30121-9","article-title":"Development and validation of multivariable prediction models of remission, recovery, and quality of life outcomes in people with first episode psychosis: a machine learning approach","volume":"1","author":"Leighton","year":"2019","journal-title":"Lancet Digit. Health"},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0150","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1093\/schbul\/sbu001","article-title":"Dose equivalents for second-generation antipsychotics: the minimum effective dose method","volume":"40","author":"Leucht","year":"2014","journal-title":"Schizophr. Bull."},{"issue":"Suppl. 1","key":"10.1016\/j.schres.2025.09.023_bb0155","doi-asserted-by":"crossref","first-page":"S90","DOI":"10.1093\/schbul\/sbv167","article-title":"Dose equivalents for antipsychotic drugs: the DDD method","volume":"42","author":"Leucht","year":"2016","journal-title":"Schizophr. Bull."},{"issue":"4","key":"10.1016\/j.schres.2025.09.023_bb0160","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1176\/appi.ajp.2019.19010034","article-title":"Dose-response meta-analysis of antipsychotic drugs for acute schizophrenia","volume":"177","author":"Leucht","year":"2020","journal-title":"Am. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2025.09.023_bb0165","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/wps.20809","article-title":"The clinical characterization of the patient with primary psychosis aimed at personalization of management","volume":"20","author":"Maj","year":"2021","journal-title":"World Psychiatry"},{"issue":"7","key":"10.1016\/j.schres.2025.09.023_bb0170","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.biopsych.2023.04.004","article-title":"Data-driven taxonomy for antipsychotic medication: a new classification system","volume":"94","author":"McCutcheon","year":"2023","journal-title":"Biol. Psychiatry"},{"issue":"11","key":"10.1016\/j.schres.2025.09.023_bb0175","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1007\/s00127-021-02047-3","article-title":"The associations between migrant status and ethnicity and the identification of individuals at ultra-high risk for psychosis and transition to psychosis: a systematic review","volume":"56","author":"Moore","year":"2021","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"key":"10.1016\/j.schres.2025.09.023_bb0180","article-title":"The acceptable R-square in empirical modelling for social science research","author":"Ozili","year":"2022","journal-title":"Soc. Res. Methodol. Publ."},{"issue":"3","key":"10.1016\/j.schres.2025.09.023_bb0185","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.comppsych.2011.04.007","article-title":"The symptom and function dimensions of the Global Assessment of Functioning (GAF) scale","volume":"53","author":"Pedersen","year":"2012","journal-title":"Compr. Psychiatry"},{"key":"10.1016\/j.schres.2025.09.023_bb0190","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.comppsych.2006.03.008","article-title":"Generalizability studies of the Global assessment of functioning\u2013split version","volume":"48","author":"Pedersen","year":"2007","journal-title":"Compr. Psychiatry"},{"issue":"5","key":"10.1016\/j.schres.2025.09.023_bb0195","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1093\/schbul\/sbz054","article-title":"Estimating exposome score for schizophrenia using predictive modeling approach in two independent samples: the results from the EUGEI study","volume":"45","author":"Pries","year":"2019","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.schres.2025.09.023_bb0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S2045796020000943","article-title":"Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum","volume":"29","author":"Pries","year":"2020","journal-title":"Epidemiol. Psychiatr. Sci."},{"issue":"12","key":"10.1016\/j.schres.2025.09.023_bb0205","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1001\/jamapsychiatry.2020.2304","article-title":"Association of recent stressful life events with mental and physical health in the context of genomic and exposomic liability for schizophrenia","volume":"77","author":"Pries","year":"2020","journal-title":"JAMA Psychiatr."},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0210","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1093\/schbul\/sbaa170","article-title":"Predictive performance of exposome score for schizophrenia in the general population","volume":"47","author":"Pries","year":"2021","journal-title":"Schizophr. Bull."},{"issue":"3","key":"10.1016\/j.schres.2025.09.023_bb0215","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.bpsgos.2022.05.005","article-title":"Estimating the association between exposome and psychosis as well as general psychopathology: results from the ABCD study","volume":"2","author":"Pries","year":"2022","journal-title":"Biol. Psychiatry Glob. Open Sci."},{"issue":"12","key":"10.1016\/j.schres.2025.09.023_bb0220","doi-asserted-by":"crossref","first-page":"5551","DOI":"10.1017\/S0033291722002756","article-title":"Bidirectional relationships between cannabis use, anxiety and depressive symptoms in the mediation of the association with psychotic experience: further support for an affective pathway to psychosis","volume":"53","author":"Radhakrishnan","year":"2023","journal-title":"Psychol. Med."},{"key":"10.1016\/j.schres.2025.09.023_bb0225","doi-asserted-by":"crossref","DOI":"10.1176\/appi.ajp.161.3.473","article-title":"Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder","volume":"161","author":"Robinson","year":"2004","journal-title":"Am. J. Psychiatry"},{"issue":"4","key":"10.1016\/j.schres.2025.09.023_bb0230","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/JCP.0000000000001224","article-title":"General functioning in patients with first-episode psychosis after the first 18 months of treatment","volume":"40","author":"Rojnic Kuzman","year":"2020","journal-title":"J. Clin. Psychopharmacol."},{"issue":"3","key":"10.1016\/j.schres.2025.09.023_bb2000","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1093\/biomet\/63.3.581","article-title":"Inference and missing data","volume":"63","author":"Rubin","year":"1976","journal-title":"Biometrika"},{"key":"10.1016\/j.schres.2025.09.023_bb0235","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1093\/schbul\/sbv058","article-title":"Feasibility and effectiveness of a multi-element psychosocial intervention for first-episode psychosis: results from the cluster-randomized controlled GET UP PIANO trial in a catchment area of 10 million inhabitants","volume":"41","author":"Ruggeri","year":"2015","journal-title":"Schizophr. Bull."},{"issue":"11","key":"10.1016\/j.schres.2025.09.023_bb0240","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/j.euroneuro.2014.08.009","article-title":"Equipercentile linking of scales measuring functioning and symptoms: examining the GAF, SOFAS, CGI-S, and PANSS","volume":"24","author":"Samara","year":"2014","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.schres.2025.09.023_bb1000","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.cpr.2017.09.007","article-title":"Predictors of functional recovery in first-episode psychosis: a systematic review and meta-analysis of longitudinal studies","volume":"58","author":"Santesteban-Echarri","year":"2017","journal-title":"Clin. Psychol. Rev."},{"issue":"3","key":"10.1016\/j.schres.2025.09.023_bb0245","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1348\/0261510041552756","article-title":"Lonely in the crowd: Recollections of bullying","volume":"22","author":"Sch\u00e4fer","year":"2004","journal-title":"Br. J. Dev. Psychol."},{"issue":"3","key":"10.1016\/j.schres.2025.09.023_bb0260","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1093\/schbul\/sbv154","article-title":"Cannabis use is associated with increased psychotic symptoms and poorer psychosocial functioning in first-episode psychosis: a report from the UK National EDEN Study","volume":"42","author":"Seddon","year":"2015","journal-title":"Schizophr. Bull."},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0265","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/wps.20745","article-title":"Transdiagnostic clinical staging in youth mental health: a first international consensus statement","volume":"19","author":"Shah","year":"2020","journal-title":"World Psychiatry"},{"issue":"1","key":"10.1016\/j.schres.2025.09.023_bb0270","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/schbul\/sbab107","article-title":"Prediction of early symptom remission in two independent samples of first-episode psychosis patients using machine learning","volume":"48","author":"Soldatos","year":"2022","journal-title":"Schizophr. Bull."},{"issue":"2","key":"10.1016\/j.schres.2025.09.023_bb0275","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.psychres.2015.02.024","article-title":"Relationships between global assessment of functioning and other rating scales in clinical trials for schizophrenia","volume":"227","author":"Suzuki","year":"2015","journal-title":"Psychiatry Res."},{"issue":"7906","key":"10.1016\/j.schres.2025.09.023_bb3000","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/s41586-022-04434-5","article-title":"Mapping genomic loci implicates genes and synaptic biology in schizophrenia","volume":"604","author":"Trubetskoy","year":"2022","journal-title":"Nature"},{"issue":"7321","key":"10.1016\/j.schres.2025.09.023_bb0280","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nature09563","article-title":"The environment and schizophrenia","volume":"468","author":"van Os","year":"2010","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.schres.2025.09.023_bb0285","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1093\/schbul\/sbu069","article-title":"Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations","volume":"40","author":"van Os","year":"2014","journal-title":"Schizophr. Bull."},{"issue":"9","key":"10.1016\/j.schres.2025.09.023_bb0290","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1001\/jamapsychiatry.2013.19","article-title":"Recovery in remitted first-episode psychosis at 7 years of follow-up of an early dose reduction\/discontinuation or maintenance treatment strategy: long-term follow-up of a 2-year randomized clinical trial","volume":"70","author":"Wunderink","year":"2013","journal-title":"JAMA Psychiatr."}],"container-title":["Schizophrenia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996425003330?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920996425003330?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:38:39Z","timestamp":1777581519000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920996425003330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":59,"alternative-id":["S0920996425003330"],"URL":"https:\/\/doi.org\/10.1016\/j.schres.2025.09.023","relation":{},"ISSN":["0920-9964"],"issn-type":[{"value":"0920-9964","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between the exposome score for schizophrenia and functioning in remitted first-episode psychosis: results from the HAMLETT study","name":"articletitle","label":"Article Title"},{"value":"Schizophrenia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.schres.2025.09.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}