{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:00:40Z","timestamp":1791561640190,"version":"4.3.4"},"reference-count":50,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100019330","name":"Shanghai Clinical Research Center for Mental Health","doi-asserted-by":"publisher","award":["19MC1911100"],"award-info":[{"award-number":["19MC1911100"]}],"id":[{"id":"10.13039\/501100019330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022821","name":"Shanghai Key Laboratory of Psychotic Disorders","doi-asserted-by":"publisher","award":["13dz2260500"],"award-info":[{"award-number":["13dz2260500"]}],"id":[{"id":"10.13039\/100022821","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012151","name":"Sanming Project of Medicine in Shenzen Municipality","doi-asserted-by":"publisher","award":["SZSM202311019"],"award-info":[{"award-number":["SZSM202311019"]}],"id":[{"id":"10.13039\/501100012151","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012151","name":"Sanming Project of Medicine in Shenzen Municipality","doi-asserted-by":"publisher","award":["82100879"],"award-info":[{"award-number":["82100879"]}],"id":[{"id":"10.13039\/501100012151","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFA1004804"],"award-info":[{"award-number":["2022YFA1004804"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010167","name":"Shanghai Shen Kang Hospital Development Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010167","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270907"],"award-info":[{"award-number":["82270907"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92357305"],"award-info":[{"award-number":["92357305"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82022012"],"award-info":[{"award-number":["82022012"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020732","name":"Innovative Research Team of High-level Local University in Shanghai","doi-asserted-by":"publisher","award":["SHSMU-ZDCX20212700"],"award-info":[{"award-number":["SHSMU-ZDCX20212700"]}],"id":[{"id":"10.13039\/100020732","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science Bulletin"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.scib.2026.06.021","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:43:06Z","timestamp":1780936986000},"page":"3380-3392","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multidimensional effects of personalized exercise intervention in type 2 diabetes: a randomized controlled trial"],"prefix":"10.1016","volume":"71","author":[{"given":"Dan","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piao","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chufan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfeng","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyi","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangtian","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenli","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiacheng","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huasheng","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianshu","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaohui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanxiang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haokai","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luling","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyue","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paddy C.","family":"Dempsey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan P.","family":"Little","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Andrew","family":"Tse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiarui","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueqiong","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qichen","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiping","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huating","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scib.2026.06.021_b0005","unstructured":"American Diabetes Association. 2. Diagnosis and classification of diabetes: standards of care in diabetes-2024. Diabetes Care 2024;47:S20\u201342."},{"key":"10.1016\/j.scib.2026.06.021_b0010","doi-asserted-by":"crossref","unstructured":"American Diabetes Association. 8. Obesity and weight management for the prevention and treatment of type 2 diabetes: standards of care in diabetes-2024. Diabetes Care 2024;47:S145\u201357.","DOI":"10.2337\/dc24-S008"},{"key":"10.1016\/j.scib.2026.06.021_b0015","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1161\/CIRCULATIONAHA.124.067676","article-title":"Muscle mass and glucagon-like peptide-1 receptor agonists: adaptive or maladaptive response to weight loss?","volume":"150","author":"Linge","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.scib.2026.06.021_b0020","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S2213-8587(25)00027-0","article-title":"Tirzepatide and muscle composition changes in people with type 2 diabetes (SURPASS-3 MRI): a post-hoc analysis of a randomised, open-label, parallel-group, phase 3 trial","volume":"13","author":"Sattar","year":"2025","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.scib.2026.06.021_b0025","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S2213-8587(14)70034-8","article-title":"Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases","volume":"2","author":"Kalyani","year":"2014","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.scib.2026.06.021_b0030","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.2337\/dc09-0264","article-title":"Excessive loss of skeletal muscle mass in older adults with type 2 diabetes","volume":"32","author":"Park","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.scib.2026.06.021_b0035","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"10.1016\/j.scib.2026.06.021_b0040","article-title":"Epidemiology of sarcopenia: prevalence, risk factors, and consequences","volume":"144","author":"Yuan","year":"2023","journal-title":"Metabolism"},{"key":"10.1016\/j.scib.2026.06.021_b0045","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.2337\/dci23-0100","article-title":"Incretin-based weight loss pharmacotherapy: can resistance exercise optimize changes in body composition?","volume":"47","author":"Locatelli","year":"2024","journal-title":"Diabetes Care"},{"key":"10.1016\/j.scib.2026.06.021_b0050","doi-asserted-by":"crossref","DOI":"10.1111\/obr.13256","article-title":"Effect of exercise training on weight loss, body composition changes, and weight maintenance in adults with overweight or obesity: an overview of 12 systematic reviews and 149 studies","volume":"22","author":"Bellicha","year":"2021","journal-title":"Obes Rev"},{"key":"10.1016\/j.scib.2026.06.021_b0055","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1056\/NEJMoa1212914","article-title":"Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes","volume":"369","author":"Wing","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.scib.2026.06.021_b0060","doi-asserted-by":"crossref","first-page":"357","DOI":"10.7326\/0003-4819-147-6-200709180-00005","article-title":"Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial","volume":"147","author":"Sigal","year":"2007","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.scib.2026.06.021_b0065","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/S1474-4422(20)30139-3","article-title":"Understanding multifactorial brain changes in type 2 diabetes: a biomarker perspective","volume":"19","author":"Biessels","year":"2020","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.scib.2026.06.021_b0070","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1136\/bjsports-2024-108589","article-title":"Effectiveness of exercise for improving cognition, memory and executive function: a systematic umbrella review and meta-meta-analysis","volume":"59","author":"Singh","year":"2025","journal-title":"Br J Sports Med"},{"key":"10.1016\/j.scib.2026.06.021_b0075","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1007\/s12020-015-0792-6","article-title":"Exercise and diabetes: relevance and causes for response variability","volume":"51","author":"B\u00f6hm","year":"2016","journal-title":"Endocrine"},{"key":"10.1016\/j.scib.2026.06.021_b0080","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s11154-025-09963-8","article-title":"Weight cycling and its effects on muscle mass, sarcopenia and sarcopenic obesity","volume":"26","author":"Zamboni","year":"2025","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.scib.2026.06.021_b0085","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.14283\/jpad.2024.117","article-title":"Multidomain intervention trial for preventing cognitive decline among older adults with type 2 diabetes: J-MIND-diabetes","volume":"11","author":"Sugimoto","year":"2024","journal-title":"J Prev Alzheimers Dis"},{"key":"10.1016\/j.scib.2026.06.021_b0090","article-title":"Effects of Tai Chi Chuan on cognitive function in adults 60 years or older with type 2 diabetes and mild cognitive impairment in china: a randomized clinical trial","volume":"6","author":"Chen","year":"2023","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.scib.2026.06.021_b0095","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.tics.2017.09.010","article-title":"Advances in fMRI real-time neurofeedback","volume":"21","author":"Watanabe","year":"2017","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.scib.2026.06.021_b0100","article-title":"Effects of exercise intervention on type 2 diabetes patients with abdominal obesity and low thigh circumference (EXTEND): study protocol for a randomized controlled trial","volume":"13","author":"Liu","year":"2022","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.scib.2026.06.021_b0105","doi-asserted-by":"crossref","unstructured":"American Diabetes Association. 5. Facilitating behavior change and well-being to improve health outcomes: standards of medical care in diabetes-2021. Diabetes Care 2021;44:S53\u201372.","DOI":"10.2337\/dc21-S005"},{"key":"10.1016\/j.scib.2026.06.021_b0110","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1016\/S0168-8227(11)70017-1","article-title":"Insulin therapy and exercise","volume":"93","author":"Kourtoglou","year":"2011","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.scib.2026.06.021_b0115","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/nimg.2001.0978","article-title":"Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain","volume":"15","author":"Tzourio-Mazoyer","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.scib.2026.06.021_b0120","article-title":"Uncovering dark mass in population proteomics: pan-analysis of single amino acid polymorphism relevant to cognition and aging","volume":"5","author":"Gao","year":"2025","journal-title":"Cell Genom"},{"key":"10.1016\/j.scib.2026.06.021_b0125","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1007\/s40279-019-01167-w","article-title":"The effect of low-volume high-intensity interval training on body composition and cardiorespiratory fitness: a systematic review and meta-analysis","volume":"49","author":"Sultana","year":"2019","journal-title":"Sports Med"},{"key":"10.1016\/j.scib.2026.06.021_b0130","doi-asserted-by":"crossref","first-page":"39","DOI":"10.11138\/jts\/2016.4.1.039","article-title":"An update on the grading of muscle injuries: a narrative review from clinical to comprehensive systems","volume":"4","author":"Grassi","year":"2016","journal-title":"Joints"},{"key":"10.1016\/j.scib.2026.06.021_b0135","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/dmrr.2514","article-title":"Physical exercise as therapy for type 2 diabetes mellitus","volume":"30","author":"Balducci","year":"2014","journal-title":"Diabetes Metab Res Rev"},{"key":"10.1016\/j.scib.2026.06.021_b0140","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.13733","article-title":"Effect of weight loss via severe vs moderate energy restriction on lean mass and body composition among postmenopausal women with obesity: the TEMPO Diet randomized clinical trial","volume":"2","author":"Seimon","year":"2019","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.scib.2026.06.021_b0145","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1016\/S0140-6736(19)31138-9","article-title":"Sarcopenia","volume":"393","author":"Cruz-Jentoft","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.scib.2026.06.021_b0150","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/s42255-023-00799-7","article-title":"Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial","volume":"5","author":"Legaard","year":"2023","journal-title":"Nat Metab"},{"key":"10.1016\/j.scib.2026.06.021_b0155","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1007\/s00125-017-4461-6","article-title":"Exercise training response heterogeneity: physiological and molecular insights","volume":"60","author":"Sparks","year":"2017","journal-title":"Diabetologia"},{"key":"10.1016\/j.scib.2026.06.021_b0160","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1136\/bjsports-2018-100328","article-title":"Precision exercise medicine: understanding exercise response variability","volume":"53","author":"Ross","year":"2019","journal-title":"Br J Sports Med"},{"key":"10.1016\/j.scib.2026.06.021_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.medp.2025.100111","article-title":"Age at diabetes diagnosis, genetic susceptibility and dementia risk: a prospective study of 13,126 participants from the UK Biobank","volume":"2","author":"Yuan","year":"2025","journal-title":"Med Plus"},{"key":"10.1016\/j.scib.2026.06.021_b0170","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0140-6736(20)30367-6","article-title":"Dementia prevention, intervention, and care: 2020 report of the Lancet Commission","volume":"396","author":"Livingston","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.scib.2026.06.021_b0175","doi-asserted-by":"crossref","first-page":"3756","DOI":"10.1016\/j.scib.2024.09.005","article-title":"The mechanisms, hallmarks, and therapies for brain aging and age-related dementia","volume":"69","author":"Jin","year":"2024","journal-title":"Sci Bull"},{"key":"10.1016\/j.scib.2026.06.021_b0180","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0140-6736(25)00184-9","article-title":"Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing","volume":"405","author":"Tari","year":"2025","journal-title":"Lancet"},{"key":"10.1016\/j.scib.2026.06.021_b0185","doi-asserted-by":"crossref","first-page":"4075","DOI":"10.1038\/s41591-025-03955-6","article-title":"Physical activity as a modifiable risk factor in preclinical Alzheimer\u2019s disease","author":"Yau","year":"2025","journal-title":"Nat Med"},{"key":"10.1016\/j.scib.2026.06.021_b0190","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/nature06976","article-title":"What we can do and what we cannot do with fMRI","volume":"453","author":"Logothetis","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.scib.2026.06.021_b0195","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.neubiorev.2009.04.001","article-title":"Intelligence and neural efficiency","volume":"33","author":"Neubauer","year":"2009","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.scib.2026.06.021_b0200","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1016\/j.clnu.2019.12.014","article-title":"Sarcopenia and cognitive impairment: a systematic review and meta-analysis","volume":"39","author":"Peng","year":"2020","journal-title":"Clin Nutr"},{"key":"10.1016\/j.scib.2026.06.021_b0205","article-title":"The relationship between skeletal muscle mass and cognitive impairment in older adults: a longitudinal study based on CLHLS","volume":"13","author":"Feng","year":"2025","journal-title":"Front Public Health"},{"key":"10.1016\/j.scib.2026.06.021_b0210","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1161\/CIRCRESAHA.124.325614","article-title":"Skeletal muscle as a mediator of interorgan crosstalk during exercise: implications for aging and obesity","volume":"136","author":"Shero","year":"2025","journal-title":"Circ Res"},{"key":"10.1016\/j.scib.2026.06.021_b0215","doi-asserted-by":"crossref","DOI":"10.1111\/apha.13766","article-title":"Factors mediating exercise-induced organ crosstalk","volume":"234","author":"Sabaratnam","year":"2022","journal-title":"Acta Physiol"},{"key":"10.1016\/j.scib.2026.06.021_b0220","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.3390\/nu15081853","article-title":"Sarcopenia and cognitive decline in older adults: targeting the muscle-brain axis","volume":"15","author":"Arosio","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.scib.2026.06.021_b0225","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.scib.2025.12.046","article-title":"Calenduloside E produced by Bifidobacterium animalis B960 increases glibenclamide efficacy and alleviates drug-induced adverse effects in a type 2 diabetes model","volume":"71","author":"Shen","year":"2026","journal-title":"Sci Bull"},{"key":"10.1016\/j.scib.2026.06.021_b0230","first-page":"1","article-title":"The effects of exercise on complement system proteins in humans: a systematic scoping review","volume":"28","author":"Rothschild-Rodriguez","year":"2022","journal-title":"Exerc Immunol Rev"},{"key":"10.1016\/j.scib.2026.06.021_b0235","doi-asserted-by":"crossref","first-page":"297","DOI":"10.2147\/JIR.S170262","article-title":"Cell adhesion molecules and exercise","volume":"11","author":"Koh","year":"2018","journal-title":"J Inflamm Res"},{"key":"10.1016\/j.scib.2026.06.021_b0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2025.102955","article-title":"The muscle-brain axis in type 2 diabetes: molecular pathways linking sarcopenia and cognitive decline","volume":"113","author":"Xenos","year":"2026","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.scib.2026.06.021_b0245","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1016\/j.scib.2024.09.022","article-title":"Blood-derived factors to brain communication in brain diseases","volume":"69","author":"He","year":"2024","journal-title":"Sci Bull"},{"key":"10.1016\/j.scib.2026.06.021_b0250","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.molmed.2008.09.009","article-title":"C1, MBL-MASPs and C1-inhibitor: novel approaches for targeting complement-mediated inflammation","volume":"14","author":"Beinrohr","year":"2008","journal-title":"Trends Mol Med"}],"container-title":["Science Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095927326006572?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095927326006572?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T19:25:56Z","timestamp":1784748356000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2095927326006572"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":50,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S2095927326006572"],"URL":"https:\/\/doi.org\/10.1016\/j.scib.2026.06.021","relation":{},"ISSN":["2095-9273"],"issn-type":[{"value":"2095-9273","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multidimensional effects of personalized exercise intervention in type 2 diabetes: a randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Science Bulletin","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scib.2026.06.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Science China Press. Published by Elsevier B.V. and Science China Press. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}