{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:37:12Z","timestamp":1791599832234,"version":"4.3.4"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science & Justice"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.scijus.2021.02.003","type":"journal-article","created":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T07:21:35Z","timestamp":1615101695000},"page":"221-226","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Model for the prediction of mechanical asphyxia as the cause of death based on four biological indexes in human cardiac tissue"],"prefix":"10.1016","volume":"61","author":[{"given":"Liujun","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wencan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yikai","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianlong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaijun","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bi","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geng","family":"Fei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scijus.2021.02.003_b0005","unstructured":"Forensic Pathology. Mosby, Incorporated, 1998."},{"key":"10.1016\/j.scijus.2021.02.003_b0010","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jflm.2016.05.001","article-title":"Retrospective analysis of 319 hanging and strangulation cases between 2001 and 2014 in Shanghai","volume":"42","author":"Ma","year":"2016","journal-title":"J. Forensic Leg. Med."},{"key":"10.1016\/j.scijus.2021.02.003_b0015","first-page":"1","article-title":"DUSP1 and KCNJ2 mRNA upregulation can serve as a biomarker of mechanical asphyxia-induced death in cardiac tissue","volume":"132","author":"Yan","year":"2017","journal-title":"Int. J. Legal Med."},{"key":"10.1016\/j.scijus.2021.02.003_b0020","doi-asserted-by":"crossref","first-page":"74526","DOI":"10.18632\/oncotarget.12931","article-title":"G6PC3, ALDOA and CS induction accompanies mir-122 down-regulation in the mechanical asphyxia and can serve as hypoxia biomarkers","volume":"7","author":"Zeng","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.scijus.2021.02.003_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2020.110293","article-title":"Identification of the miRNA-3185\/CYP4A11 axis in cardiac tissue as a biomarker for mechanical asphyxia","volume":"311","author":"Han","year":"2020","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.scijus.2021.02.003_b0030","doi-asserted-by":"crossref","first-page":"1T","DOI":"10.1088\/1361-6560\/aab4b1","article-title":"Receiver operating characteristic (ROC) curves: review of methods with applications in diagnostic medicine","volume":"63","author":"Obuchowski","year":"2018","journal-title":"Phys. Med. Biol."},{"key":"10.1016\/j.scijus.2021.02.003_b0035","first-page":"307","article-title":"Receiver operating characteristic (ROC) methodology: the state of the art","volume":"29","author":"Hanley","year":"1989","journal-title":"Crit. Rev. Diagn. Imaging"},{"key":"10.1016\/j.scijus.2021.02.003_b0040","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1177\/0272989X17732994","article-title":"Simple decision-analytic functions of the AUC for ruling out a risk prediction model and an added predictor","volume":"38","author":"Baker","year":"2018","journal-title":"Med. Decis. Making"},{"key":"10.1016\/j.scijus.2021.02.003_b0045","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1016\/j.jtcvs.2017.12.107","article-title":"Nomogram: an analogue tool to deliver digital knowledge","volume":"155","author":"Park","year":"2018","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.scijus.2021.02.003_b0050","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1007\/s12024-015-9703-7","article-title":"Exploration of the R code-based mathematical model for PMI estimation using profiling of RNA degradation in rat brain tissue at different temperatures","volume":"11","author":"Ma","year":"2015","journal-title":"Forensic Sci. Med. Pathol."},{"key":"10.1016\/j.scijus.2021.02.003_b0055","doi-asserted-by":"crossref","first-page":"211","DOI":"10.21037\/atm.2017.04.01","article-title":"Drawing Nomograms with R: applications to categorical outcome and survival data","volume":"5","author":"Zhang","year":"2017","journal-title":"Ann Transl Med"},{"key":"10.1016\/j.scijus.2021.02.003_b0060","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.scijus.2012.11.005","article-title":"The selection of endogenous genes in human postmortem tissues","volume":"53","author":"Zhang","year":"2013","journal-title":"Sci. Justice J. Forensic Sci. Soc."},{"key":"10.1016\/j.scijus.2021.02.003_b0065","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1111\/1556-4029.12447","article-title":"A time course study demonstrating mRNA, microRNA, 18S rRNA, and U6 snRNA changes to estimate PMI in deceased rat's spleen","volume":"59","author":"Lv","year":"2015","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.scijus.2021.02.003_b0070","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00414-014-1066-1","article-title":"Molecular analysis of different classes of RNA molecules from formalin-fixed paraffin-embedded autoptic tissues: a pilot study","volume":"129","author":"Muciaccia","year":"2015","journal-title":"Int. J. Legal Med."},{"key":"10.1016\/j.scijus.2021.02.003_b0075","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s00428-013-1485-2","article-title":"High stability of microRNAs in tissue samples of compromised quality","volume":"463","author":"Peir\u00f3-Chova","year":"2013","journal-title":"Virchows Archiv. Int. J. Pathol."},{"key":"10.1016\/j.scijus.2021.02.003_b0080","doi-asserted-by":"crossref","first-page":"12890","DOI":"10.1074\/jbc.274.18.12890","volume":"274","author":"Laderoute","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scijus.2021.02.003_b0085","doi-asserted-by":"crossref","first-page":"44405","DOI":"10.1074\/jbc.M103346200","article-title":"Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis","volume":"276","author":"Seta","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scijus.2021.02.003_b0090","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1213\/ane.0b013e3181733f6f","article-title":"Neuroprotective strategies for the neonatal brain","volume":"106","author":"Degos","year":"2008","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.scijus.2021.02.003_b0095","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.003666","article-title":"Obstructive sleep apnea and circulating potassium channel levels","volume":"5","author":"Jiang","year":"2016","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.scijus.2021.02.003_b0100","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1152\/physrev.00021.2009","article-title":"Inwardly rectifying potassium channels: their structure, function, and physiological roles","volume":"90","author":"Hibino","year":"2010","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.scijus.2021.02.003_b0105","doi-asserted-by":"crossref","first-page":"29241","DOI":"10.1074\/jbc.R109.025544","article-title":"Glucose-6-phosphatase catalytic subunit gene family","volume":"284","author":"Hutton","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scijus.2021.02.003_b0110","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1093\/nar\/gkm1113","article-title":"Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver","volume":"36","author":"Elm\u00e9n","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scijus.2021.02.003_b0115","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/ncb3094","article-title":"Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis","volume":"17","author":"Fong","year":"2015","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.scijus.2021.02.003_b0120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0066676","article-title":"Integrated miRNA-mRNA analysis revealing the potential roles of miRNAs in chordomas","volume":"8","author":"Long","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.scijus.2021.02.003_b0125","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1002\/jcp.22899","article-title":"Post-transcriptional regulation of the Ras-ERK\/MAPK signaling pathway","volume":"227","author":"Whelan","year":"2012","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.scijus.2021.02.003_b0130","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/01.paf.0000221082.72186.2e","article-title":"Asphyxial deaths: a retrospective study and review of the literature","volume":"27","author":"Azmak","year":"2006","journal-title":"Am. J. Forensic Med. Pathol."},{"key":"10.1016\/j.scijus.2021.02.003_b0135","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jcmg.2017.03.018","article-title":"Development and validation of a simple-to-use nomogram for predicting 5-, 10-, and 15-year survival in asymptomatic adults undergoing coronary artery calcium scoring","volume":"11","author":"Hb","year":"2018","journal-title":"JACC Cardiovasc. Imaging"},{"key":"10.1016\/j.scijus.2021.02.003_b0140","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1001\/jamasurg.2015.4257","article-title":"Nomogram for preoperative estimation of microvascular invasion risk in hepatitis B virus-related hepatocellular carcinoma within the Milan criteria","volume":"151","author":"Lei","year":"2016","journal-title":"JAMA SURG"}],"container-title":["Science & Justice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1355030621000095?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1355030621000095?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:48:08Z","timestamp":1761180488000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1355030621000095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S1355030621000095"],"URL":"https:\/\/doi.org\/10.1016\/j.scijus.2021.02.003","relation":{},"ISSN":["1355-0306"],"issn-type":[{"value":"1355-0306","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Model for the prediction of mechanical asphyxia as the cause of death based on four biological indexes in human cardiac tissue","name":"articletitle","label":"Article Title"},{"value":"Science & Justice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scijus.2021.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Chartered Society of Forensic Sciences. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}