{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T16:42:51Z","timestamp":1775407371705,"version":"3.50.1"},"reference-count":95,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.scitotenv.2012.11.100","type":"journal-article","created":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T15:12:40Z","timestamp":1357917160000},"page":"64-78","source":"Crossref","is-referenced-by-count":68,"special_numbering":"C","title":["Presence and hazards of nutrients and emerging organic micropollutants from sewage lagoon discharges into Dead Horse Creek, Manitoba, Canada"],"prefix":"10.1016","volume":"445-446","author":[{"given":"Jules C.","family":"Carlson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie C.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer E.","family":"Low","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Cardinal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott D.","family":"MacKenzie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah A.","family":"Beattie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan K.","family":"Challis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renee J.","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie S.","family":"Meronek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca P.A.","family":"Wilks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M.","family":"Buhay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles S.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark L.","family":"Hanson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2012.11.100_bb0005","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1897\/03-603","article-title":"Development of a passive, in situ, integrative sampler for hydrophilic organic contaminants in aquatic environments","volume":"23","author":"Alvarez","year":"2004","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0010","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.pestbp.2005.03.001","article-title":"Acute toxicity of diazinon on the common carp (Cyprinus carpio L.) embryos and larvae","volume":"82","author":"Aydin","year":"2005","journal-title":"Pest Biochem Physiol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0015","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/etc.5620190109","article-title":"Diazinon and chloropyrifos in urban waterways in Northern California, USA","volume":"19","author":"Bailey","year":"2000","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0020","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.envpol.2008.11.025","article-title":"The occurrence of illicit and therapeutic pharmaceuticals in wastewater effluent and surface waters in Nebraska","volume":"157","author":"Bartelt-Hunt","year":"2009","journal-title":"Environ Pollut"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0025","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.aquabot.2006.11.002","article-title":"Effects of the herbicide 2,4-D on the growth of nine aquatic macrophytes","volume":"86","author":"Belgers","year":"2007","journal-title":"Aquat Bot"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0030","doi-asserted-by":"crossref","first-page":"17","DOI":"10.2307\/1468279","article-title":"Eutrophication of streams and rivers: dissolved nutrient\u2013chlorophyll relationships for benthic algae","volume":"19","author":"Biggs","year":"2000","journal-title":"J N Am Benthol Soc"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0035","doi-asserted-by":"crossref","first-page":"29","DOI":"10.14210\/bjast.v10n2.p29-51","article-title":"Ecotoxicity of selected pharmaceuticals of urban origin discharged to the Saint-Lawrence River (Quebec, Canada): a review","volume":"10","author":"Blaise","year":"2006","journal-title":"Braz J Aquat Sci Technol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0040","series-title":"Water Quality Management Section. Manitoba Conservation Report No. 2002\u201304","article-title":"A preliminary estimate of total nitrogen and total phosphorus loading to streams in Manitoba, Canada","author":"Bourne","year":"2002"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0045","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s10750-004-0189-7","article-title":"Water quality of effluent-dominated ecosystems: ecotoxicological, hydrological, and management considerations","volume":"556","author":"Brooks","year":"2006","journal-title":"Hydrobiologica"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0050","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1016\/S0043-1354(03)00135-0","article-title":"Pollutant removal from municipal sewage lagoon effluents with a free-surface wetland","volume":"37","author":"Cameron","year":"2003","journal-title":"Water Res"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0055","author":"Canadian Council of Ministers of the Environment"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0060","unstructured":"Carlson JC, Challis JK, Hanson, ML, Wong CS. Stability of pharmaceuticals and other organics stored on passive organic chemical integrative samplers and solid phase extraction cartridges. Environ Toxicol Chem in press; 32. http:\/\/dx.doi.org\/10.10002\/etc.2076."},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0065","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1890\/1051-0761(1998)008[0559:NPOSWW]2.0.CO;2","article-title":"Nonpoint pollution of surface waters with phosphorus and nitrogen","volume":"8","author":"Carpenter","year":"1998","journal-title":"Ecol Appl"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0070","first-page":"105","article-title":"Accuracy of current meter measurements","volume":"89","author":"Carter","year":"1963","journal-title":"Am Soc Civil Eng Proc J Hydraul Div"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0075","series-title":"Techniques of Water-Resources Investigations of the United States Geological Survey","article-title":"Book 3, chapter A6: general procedure for gaging streams","author":"Carter","year":"1989"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0080","series-title":"Nutrients and their impact on the Canadian environment","author":"Chambers","year":"2001"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0085","series-title":"Water and Waste Department report","article-title":"Environmental assessment of Canadian strategic infrastructure funded upgrades to the City of Winnipeg water pollution control centre","author":"City of Winnipeg","year":"2006"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0090","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0378-4274(03)00068-7","article-title":"Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects","volume":"142","author":"Cleuvers","year":"2003","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0095","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0147-6513(03)00141-6","article-title":"Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid","volume":"59","author":"Cleuvers","year":"2004","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0100","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.chemosphere.2004.11.090","article-title":"Initial risk assessment for three \u03b2-blockers found in the aqueous environment","volume":"59","author":"Cleuvers","year":"2005","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0105","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.scitotenv.2008.02.031","article-title":"The occurrence of acidic drugs and caffeine in sewage effluents and receiving waters from three coastal watersheds in Atlantic Canada","volume":"396","author":"Comeau","year":"2008","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0110","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/j.chemosphere.2008.09.020","article-title":"Reduction of pharmaceutically active compounds by a lagoon wetland wastewater system in southeast Louisiana","volume":"13","author":"Conkle","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0115","doi-asserted-by":"crossref","first-page":"261","DOI":"10.2134\/jeq1998.00472425002700020004x","article-title":"The role of phosphorus in the eutrophication of receiving waters: a review","volume":"27","author":"Correll","year":"1998","journal-title":"J Environ Qual"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0120","series-title":"Standard methods for the examination of water and wastewater","year":"2005"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0125","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1016\/j.chemosphere.2004.07.017","article-title":"Evaluation of antimicrobial agents for veterinary use in the ecotoxicity test using microalgae","volume":"57","author":"Eguchi","year":"2004","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0130","first-page":"170","article-title":"Aquatic toxicity of various pharmaceuticals on some isolated plankton species","volume":"3","author":"El-Bassat","year":"2011","journal-title":"Int J Med Med Sci"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0135","series-title":"Municipal Water Use Database (MUD)","author":"Environment Canada","year":"1999"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0140","author":"Environment Canada"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0145","author":"Environment Canada and Manitoba Water Stewardship"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0150","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.aquatox.2005.09.009","article-title":"Ecotoxicology of pharmaceuticals","volume":"76","author":"Fent","year":"2006","journal-title":"Aquat Toxicol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0155","doi-asserted-by":"crossref","first-page":"7257","DOI":"10.1021\/es061308e","article-title":"Attenuation of wastewater-derived contaminants in an effluent-dominated river","volume":"40","author":"Fono","year":"2006","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0160","series-title":"Atrazine in North American surface waters: a probabilistic aquatic ecological risk assessment","author":"Giddings","year":"2005"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0165","series-title":"Surface Water Management Section, Manitoba Water Stewardship. PRAC Workshop, Winnipeg MB Sept. 20\u201321, 2011","article-title":"Update on Manitoba drought management plan","author":"Government of Manitoba","year":"2011"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0170","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1899\/0887-3593(2005)024<0029:NRIAPS>2.0.CO;2","article-title":"Nutrient retention in a point-source-enriched system","volume":"24","author":"Haggard","year":"2005","journal-title":"J N Am Benthol Soc"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0175","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.envpol.2003.12.017","article-title":"Haloacetic acids in the aquatic environment. Part II: ecological risk assessment","volume":"130","author":"Hanson","year":"2004","journal-title":"Environ Pollut"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0180","first-page":"689","article-title":"Cumulative uncertainty in measured streamflow and water quality data for small watersheds","volume":"49","author":"Harmel","year":"2006","journal-title":"Trans Am Soc Agric Biol Eng"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0185","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3329\/bjm.v23i2.869","article-title":"Load of heterotrophic and nitrifying bacteria in the sewage lagoon and receiving river Buriganga","volume":"23","author":"Hasan","year":"2006","journal-title":"Bangladesh J Microbiol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0190","author":"Health Canada"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0195","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0378-4274(02)00041-3","article-title":"Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data","volume":"131","author":"Heberer","year":"2002","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0200","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2166\/wst.2002.0060","article-title":"From municipal sewage to drinking water: fate and removal of pharmaceutical residues in the aquatic environment in urban areas","volume":"46","author":"Heberer","year":"2002","journal-title":"Water Sci Technol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0205","doi-asserted-by":"crossref","first-page":"796","DOI":"10.4319\/lo.1988.33.4_part_2.0796","article-title":"Nutrient limitation of phytoplankton in freshwater and marine environments: a recent review of evidence on the effects of enrichment","volume":"33","author":"Hecky","year":"1988","journal-title":"Limnol Oceanogr"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0210","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.scitotenv.2006.02.055","article-title":"How green is my river? A new paradigm of eutrophication in rivers","volume":"365","author":"Hilton","year":"2006","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0215","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0048-9697(98)00337-4","article-title":"Occurrence of antibiotics in the aquatic environment","volume":"225","author":"Hirsch","year":"1999","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0220","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.scitotenv.2004.11.017","article-title":"Toxic and genotoxic evaluation of six antibiotics on non-target organisms","volume":"346","author":"Isidori","year":"2005","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0225","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.scitotenv.2005.08.038","article-title":"Sewage effluent phosphorus: a greater risk to river eutrophication than agricultural phosphorus?","volume":"360","author":"Jarvie","year":"2006","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0230","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1080\/10643380590956966","article-title":"Human pharmaceuticals in wastewater treatment processes","volume":"353","author":"Jones","year":"2005","journal-title":"Crit Rev Environ Sci Technol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0235","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1111\/j.1745-6584.1984.tb01443.x","article-title":"Hydrogeochemical interaction between a municipal waste stabilization lagoon and a shallow aquifer","volume":"22","author":"Kehew","year":"1984","journal-title":"Ground Water"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0240","series-title":"Techniques of Water-Resources Investigations of the United States Geological Survey","article-title":"Book 3, chapter A10: discharge ratings at gauging stations","author":"Kennedy","year":"1984"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0245","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.envint.2006.11.017","article-title":"Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem, and six major sulfonamides, and their potential ecological risks in Korea","volume":"33","author":"Kim","year":"2007","journal-title":"Environ Int"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0250","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1021\/es011055j","article-title":"Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999\u20132000: a national reconnaissance","volume":"36","author":"Kolpin","year":"2002","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0255","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1897\/IEAM_2009-050.1","article-title":"Environmental risk assessment of human pharmaceuticals n the European Union: a case study with the \u03b2-blocker atenolol","volume":"6","author":"Kuster","year":"2009","journal-title":"Integr Environ Assess Manag"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0260","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.chemosphere.2010.12.071","article-title":"The effects of dissolved organic matter and pH on sampling rates for polar organic chemical integrative samplers (POCIS)","volume":"83","author":"Li","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0265","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.2134\/jeq2011.0054","article-title":"The effects of multiple beneficial management practices on hydrology and nutrient losses in a small watershed in the Canadian prairies","volume":"40","author":"Li","year":"2011","journal-title":"J Environ Qual"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0270","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.scitotenv.2006.03.021","article-title":"Occurrence and reductions of pharmaceuticals and personal care products and estrogens by municipal wastewater treatment plants in Ontario, Canada","volume":"367","author":"Lishman","year":"2006","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0275","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/BF01054982","article-title":"Behavioral indicators of sublethal toxicity in rainbow trout","volume":"19","author":"Little","year":"1990","journal-title":"Arch Environ Contam Toxicol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0280","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.watres.2009.09.056","article-title":"Loadings, trends, comparisons, and fate of achiral and chiral pharmaceuticals in wastewaters from urban tertiary and rural aerated lagoon treatments","volume":"44","author":"MacLeod","year":"2010","journal-title":"Water Res"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0285","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1897\/07-238.1","article-title":"Laboratory calibration and field deployment of the Polar Organic Chemical Integrative Sampler for pharmaceuticals and personal care products in wastewater and surface water","volume":"26","author":"MacLeod","year":"2007","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0290","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.trac.2007.01.002","article-title":"Water sampling: traditional methods and new approaches in water sampling strategy","volume":"26","author":"Madrid","year":"2007","journal-title":"Trends Anal Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0295","author":"Manitoba Agricultural Services Corporation"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0300","doi-asserted-by":"crossref","first-page":"85","DOI":"10.5004\/dwt.2009.359","article-title":"Waste stabilization ponds: past, present, future","volume":"4","author":"Mara","year":"2009","journal-title":"Desalin Water Treat"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0305","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.envint.2006.12.006","article-title":"Assays with Daphnia magna and Danio rerio as alert systems in aquatic toxicology","volume":"33","author":"Martins","year":"2007","journal-title":"Environ Int"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0310","doi-asserted-by":"crossref","first-page":"2872","DOI":"10.1897\/02-469","article-title":"Occurrence of neutral and acidic drugs in the effluents of Canadian sewage treatment plants","volume":"22","author":"Metcalfe","year":"2003","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0315","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s00216-006-0773-y","article-title":"Trends in monitoring pharmaceuticals and personal-care products in the aquatic environment by use of passive sampling devices","volume":"387","author":"Mills","year":"2007","journal-title":"Anal Bioanal Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0320","doi-asserted-by":"crossref","first-page":"964","DOI":"10.2175\/106143095X133194","article-title":"Modeling the fate of pesticides in municipal wastewater treatment","volume":"67","author":"Monteith","year":"1995","journal-title":"Water Environ Res"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0325","author":"Natural Resources Canada (NRCAN)"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0330","doi-asserted-by":"crossref","first-page":"6024","DOI":"10.1021\/es100779n","article-title":"Sampling for pharmaceuticals and personal care products (PPCPs) and illicit drugs in wastewater systems: are your results valid? A critical review","volume":"44","author":"Ort","year":"2010","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0335","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.4319\/lo.2011.56.4.1545","article-title":"Comment: Lake 227 shows clearly that controlling inputs of nitrogen will not reduce or prevent eutrophication of lakes","volume":"56","author":"Paterson","year":"2011","journal-title":"Limnol Oceanogr"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0340","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1139\/l88-109","article-title":"Uncertainties in the single determination of river discharge: a literature review","volume":"15","author":"Pelletier","year":"1988","journal-title":"Can J Civ Eng"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0345","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s00244-003-2313-5","article-title":"Toxicity of atrazine and molinate to the cladoceran Daphnia carinata and the effects of river water and bottom sediment on their bioavailability","volume":"46","author":"Phyu","year":"2004","journal-title":"Arch Environ Contam Toxicol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0350","doi-asserted-by":"crossref","first-page":"4474","DOI":"10.1021\/es000989p","article-title":"Seasonal and long-term nutrient trend decomposition along a spatial gradient in the Neuse River watershed","volume":"34","author":"Qian","year":"2000","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0355","series-title":"Measurement and Computation of Streamflow: Volumes I and II, USGS Water Supply Paper 2175","author":"Rantz","year":"1982"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0360","article-title":"The influence of organisms on the composition of sea water","volume":"Vol. 2","author":"Redfield","year":"1963"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0365","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1021\/es903068h","article-title":"Application and evaluation of a new passive sampler for measuring average solute concentrations in a catchment scale water quality monitoring study","volume":"44","author":"Rozemeijer","year":"2010","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0370","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0378-4274(03)00257-1","article-title":"Probabilistic hazard assessment of environmentally occurring pharmaceuticals toxicity to fish, daphnids, and algae by ECOSAR screening","volume":"144","author":"Sanderson","year":"2003","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0375","series-title":"USGS Open File Report 92\u2013144","doi-asserted-by":"crossref","DOI":"10.3133\/ofr92144","article-title":"Determination of error in individual discharge measurements","author":"Sauer","year":"1992"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0380","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1126\/science.184.4139.897","article-title":"Eutrophication and recovery in experimental lakes: implications for lake management","volume":"184","author":"Schindler","year":"1974","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0385","first-page":"317","article-title":"Effects of pesticides on blue-green algae","volume":"89","author":"Singh","year":"1973","journal-title":"Arch Microbiol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0390","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1065\/espr2002.12.142","article-title":"Eutrophication of freshwater and coastal marine ecosystems: a global problem","volume":"10","author":"Smith","year":"2003","journal-title":"Environ Sci Pollut Res"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0395","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0269-7491(99)00091-3","article-title":"Eutrophication: impacts of excess nutrient inputs on freshwater, marine, and terrestrial ecosystems","volume":"100","author":"Smith","year":"1999","journal-title":"Environ Pollut"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0400","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/etc.5620150105","article-title":"Annual review: ecological assessment of atrazine in North American surface waters","volume":"15","author":"Solomon","year":"1996","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0405","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1007\/s00244-007-9073-6","article-title":"Acute and chronic toxicity of imadocloprid to the aquatic invertebrates Chironomus tentans and Hyalalla azteca under constant- and pulse-exposure conditions","volume":"54","author":"Stoughton","year":"2008","journal-title":"Arch Environ Contam Toxicol"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0410","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1897\/06-212R.1","article-title":"Deterministic and probabilistic acute-based environmental risk assessment for naproxen for Western Europe","volume":"26","author":"Straub","year":"2007","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0415","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1002\/etc.5620190309","article-title":"Variables determining the impact of diazinon on aquatic insects: taxon, developmental stage, and exposure time","volume":"19","author":"Stuijfzand","year":"2000","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0420","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/etc.748","article-title":"Myriophyllum aquaticum versus Lemna minor: sensitivity and recovery potential after exposure to atrazine","volume":"31","author":"Teodorovi\u0107","year":"2012","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0425","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.1016\/S0043-1354(98)00099-2","article-title":"Occurrence of drugs in German sewage treatment plants and rivers","volume":"32","author":"Ternes","year":"1998","journal-title":"Water Res"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0430","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.chemosphere.2009.05.002","article-title":"Hazard identification of imidacloprid to aquatic environment","volume":"76","author":"Ti\u0161ler","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0435","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.2307\/1938119","article-title":"Retention and transport of nutrients in a third-order stream: channel processes","volume":"70","author":"Triska","year":"1989","journal-title":"Ecology"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0440","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1016\/j.ecoenv.2010.08.031","article-title":"Fish embryo toxicity of carbamazepine, diclofenac, and metaprolol","volume":"73","author":"Van den Brandhof","year":"2010","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0445","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/978-3-540-33187-2_5","article-title":"Constructed wetlands for wastewater treatment","volume":"190","author":"Vymazal","year":"2006","journal-title":"Ecol Stud"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0450","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/etc.399","article-title":"Effluent-dominated streams, Part I: presence and effects of excess nitrogen and phosphorus in Wascana Creek, Saskatchewan, Canada","volume":"30","author":"Waiser","year":"2011","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0455","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/etc.398","article-title":"Effluent-dominated streams, Part II: presence and possible effects of pharmaceuticals and personal care products in Wascana Creek, Saskatchewan, Canada","volume":"30","author":"Waiser","year":"2011","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0460","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1039\/b819464e","article-title":"JEM Spotlight: recent advances in analysis of pharmaceuticals in the environment","volume":"11","author":"Wong","year":"2009","journal-title":"J Environ Monit"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0465","first-page":"10","article-title":"Intersex and other reproductive disruption of fish in wastewater effluent dominated Colorado streams","volume":"144","author":"Woodling","year":"2006","journal-title":"Comp Biochem Physiol C"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0470","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1897\/07-471.1","article-title":"Growth-inhibiting effects of 12 antibacterial agents and their mixtures on the freshwater microalga Pseudokirchneriella subcapitata","volume":"27","author":"Yang","year":"2008","journal-title":"Environ Toxicol Chem"},{"key":"10.1016\/j.scitotenv.2012.11.100_bb0475","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1039\/b904548a","article-title":"Occurrence and removal of pharmaceutically active compounds in sewage treatment plants with different technologies","volume":"11","author":"Ying","year":"2009","journal-title":"J Environ Monit"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969712015331?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969712015331?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T16:09:19Z","timestamp":1714838959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969712015331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":95,"alternative-id":["S0048969712015331"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2012.11.100","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}