{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:21:43Z","timestamp":1791390103735,"version":"4.3.3"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"China Environmental Protection Foundation","award":["CEPF2008-123-1-5"],"award-info":[{"award-number":["CEPF2008-123-1-5"]}]},{"name":"Guangdong Province Natural Science Foundation","award":["1431520600005"],"award-info":[{"award-number":["1431520600005"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.scitotenv.2015.05.041","type":"journal-article","created":{"date-parts":[[2015,5,25]],"date-time":"2015-05-25T20:47:19Z","timestamp":1432586839000},"page":"243-248","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"special_numbering":"C","title":["Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study"],"prefix":"10.1016","volume":"529","author":[{"given":"Xiao-Di","family":"Qin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengmin","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Vaughn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Trevathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett","family":"Emo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunther","family":"Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Hui","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Tao","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-Hui","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2015.05.041_bb0035","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1289\/ehp.0901396","article-title":"Traffic-related air pollution and QT interval: modification by diabetes, obesity, and oxidative stress gene polymorphisms in the normative aging study","volume":"118","author":"Baja","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0125","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1152\/japplphysiol.01403.2003","article-title":"Effect of body size on breathing pattern and fine-particle deposition in children","volume":"97","author":"Bennett","year":"2004","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0040","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1056\/NEJMoa1000367","article-title":"Body-mass index and mortality among 1.46 million white adults","volume":"363","author":"Berrington de Gonzalez","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0130","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/risa.12125","article-title":"Physiological daily inhalation rates for health risk assessment in overweight\/obese children, adults, and elderly","volume":"34","author":"Brochu","year":"2014","journal-title":"Risk Anal."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0020","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1161\/CIR.0b013e3181dbece1","article-title":"Particulate matter air pollution and cardiovascular disease an update to the scientific statement from the American Heart Association","volume":"121","author":"Brook","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0095","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1289\/ehp.1306595","article-title":"Hemodynamic, autonomic, and vascular effects of exposure to coarse particulate matter air pollution from a rural location","volume":"122","author":"Brook","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0085","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1289\/ehp.9609","article-title":"Obesity is a modifier of autonomic cardiac responses to fine metal particulates","volume":"115","author":"Chen","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0025","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1161\/STROKEAHA.111.673442","article-title":"Acute effect of air pollution on stroke mortality in the China air pollution and health effects study","volume":"44","author":"Chen","year":"2013","journal-title":"Stroke"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0140","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1289\/ehp.0900994","article-title":"A growing role for gender analysis in air pollution epidemiology","volume":"118","author":"Clougherty","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0055","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1161\/HYPERTENSIONAHA.111.00003","article-title":"Association between long-term air pollution and increased blood pressure and hypertension in China","volume":"61","author":"Dong","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0120","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1289\/ehp.8469","article-title":"Diabetes, obesity, and hypertension may enhance associations between air pollution and markers of systemic inflammation","volume":"114","author":"Dubowsky","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0100","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.jaci.2005.02.023","article-title":"Adipose tissue, adipokines, and inflammation","volume":"115","author":"Fantuzzi","year":"2005","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0010","first-page":"251","article-title":"Outline of the report on cardiovascular disease in China, 2010","volume":"25","author":"Hu","year":"2012","journal-title":"Biomed. Environ. Sci."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0080","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/aje\/kwr511","article-title":"Air pollution and autonomic and vascular dysfunction in patients with cardiovascular disease: interactions of systemic inflammation, overweight, and gender","volume":"176","author":"Huang","year":"2012","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0145","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1289\/ehp.10851","article-title":"Season, sex, age, and education as modifiers of the effects of outdoor air pollution on daily mortality in Shanghai, China: the Public Health and Air Pollution in Asia (PAPA) Study","volume":"116","author":"Kan","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0155","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1289\/ehp.6714","article-title":"Understanding sex differences in environmental health: a thought leaders' roundtable","volume":"112","author":"Keitt","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0160","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1152\/jappl.1998.84.6.1834","article-title":"Regional deposition of inhaled particles in human lungs: comparison between men and women","volume":"84","author":"Kim","year":"1998","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0165","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1164\/ajrccm.159.3.9805036","article-title":"Increased fine particle deposition in women with asymptomatic nonspecific airway hyperresponsiveness","volume":"159","author":"Kohlh\u00e4ufl","year":"1999","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11154-013-9271-7","article-title":"Roles of adiponectin and oxidative stress in obesity-associated metabolic and cardiovascular diseases","volume":"15","author":"Matsuda","year":"2014","journal-title":"Rev. Endocr. Metab. Disord."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0005","series-title":"Global Atlas on Cardiovascular Disease Prevention and Control. World Health Organization in Collaboration with the World Heart Federation and the World Strike Organization","author":"Mendis","year":"2011"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0075","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1056\/NEJMoa054409","article-title":"Long-term exposure to air pollution and incidence of cardiovascular events in women","volume":"356","author":"Miller","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0110","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1056\/NEJMoa040967","article-title":"Inflammatory markers and the risk of coronary heart disease in men and women","volume":"351","author":"Pai","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0090","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1001\/jama.2012.3488","article-title":"Association between changes in air pollution levels during the Beijing Olympics and biomarkers of inflammation and thrombosis in healthy young adults","volume":"307","author":"Rich","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0105","doi-asserted-by":"crossref","first-page":"10497","DOI":"10.3390\/ijms140510497","article-title":"Obesity-associated oxidative stress: strategies finalized to improve redox state","volume":"14","author":"Savini","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0070","series-title":"Standardized Environmental Monitoring and Analysis Methods","author":"State Environmental Protection Administration of China (SEPA)","year":"1992"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0050","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1161\/CIRCULATIONAHA.108.799015","article-title":"Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity","volume":"119","author":"Sun","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0030","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1743-8977-9-24","article-title":"Effects of particulate matter on inflammatory markers in the general adult population","volume":"9","author":"Tsai","year":"2012","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0115","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1002\/oby.20748","article-title":"Obesity and the cardiovascular health effects of fine particulate air pollution","volume":"22","author":"Weichenthal","year":"2014","journal-title":"Obesity"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0135","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1289\/ehp.1307277","article-title":"Long-term exposure to fine particulate matter: association with nonaccidental and cardiovascular mortality in the agricultural health study cohort","volume":"122","author":"Weichenthal","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0065","series-title":"Physical Status: The Use and Interpretation of Anthropometry","author":"World Health Organization","year":"1995"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0015","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1161\/hc4601.099487","article-title":"Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization","volume":"104","author":"Yusuf","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0150","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1097\/00043764-200005000-00002","article-title":"Race, gender, and social status as modifiers of the effects of PM10 on mortality","volume":"42","author":"Zanobetti","year":"2000","journal-title":"J. Occup. Environ. Med."},{"key":"10.1016\/j.scitotenv.2015.05.041_bb0060","doi-asserted-by":"crossref","first-page":"e148","DOI":"10.1016\/j.ijcard.2013.08.071","article-title":"Does obesity amplify the association between ambient air pollution and increased blood pressure and hypertension in adults? Findings from the 33 Communities Chinese Health Study","volume":"168","author":"Zhao","year":"2013","journal-title":"Int. J. Cardiol."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969715300991?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969715300991?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,25]],"date-time":"2019-08-25T10:34:41Z","timestamp":1566729281000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969715300991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":33,"alternative-id":["S0048969715300991"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2015.05.041","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gender-specific differences of interaction between obesity and air pollution on stroke and cardiovascular diseases in Chinese adults from a high pollution range area: A large population based cross sectional study","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2015.05.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}