{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:35:40Z","timestamp":1790829340196,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003329","name":"Ministry of Economy and Competitiveness","doi-asserted-by":"publisher","award":["JPIW2013-129"],"award-info":[{"award-number":["JPIW2013-129"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["2014 SGR 291"],"award-info":[{"award-number":["2014 SGR 291"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.scitotenv.2017.05.174","type":"journal-article","created":{"date-parts":[[2017,5,28]],"date-time":"2017-05-28T22:00:31Z","timestamp":1496008831000},"page":"206-209","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":114,"special_numbering":"C","title":["Contribution of bacteriophage and plasmid DNA to the mobilization of antibiotic resistance genes in a river receiving treated wastewater discharges"],"prefix":"10.1016","volume":"601-602","author":[{"given":"Itziar","family":"Lekunberri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Villagrasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6866-9347","authenticated-orcid":false,"given":"Jos\u00e9 Luis","family":"Balc\u00e1zar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carles M.","family":"Borrego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2017.05.174_bb0005","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1093\/jac\/dku079","article-title":"Waste water effluent contributes to the dissemination of CTX-M-15 in the natural environment","volume":"69","author":"Amos","year":"2014","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0010","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/etc.2784","article-title":"Urban wastewater effluent increases antibiotic resistance gene concentrations in a receiving northern European river","volume":"34","author":"Berglund","year":"2015","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0015","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/nrmicro3380","article-title":"Molecular mechanisms of antibiotic resistance","volume":"13","author":"Blair","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017549","article-title":"Antibiotic resistance genes in the bacteriophage DNA fraction of environmental samples","volume":"6","author":"Colomer-Lluch","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0025","first-page":"1684","article-title":"Degradation of \u03b2-lactam antibiotics","volume":"87","author":"Deshpande","year":"2004","journal-title":"Curr. Sci."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0030","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/nrmicro1235","article-title":"Mobile genetic elements: the agents of open source evolution","volume":"3","author":"Frost","year":"2005","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0035","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fmicb.2013.00004","article-title":"Evolutionary consequences of antibiotic use for the resistome, mobilome and microbial pangenome","volume":"4","author":"Gillings","year":"2013","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0040","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.chroma.2012.12.072","article-title":"Rapid analysis of multiclass antibiotic residues and some of their metabolites in hospital, urban wastewater and river water by ultra-high- performance liquid chromatography coupled to quadrupole- linear ion trap tandem mass spectrometry","volume":"1292","author":"Gros","year":"2013","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0045","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.scitotenv.2013.03.071","article-title":"Exploring the links between antibiotic occurrence, antibiotic resistance, and bacterial communities in water supply reservoirs","volume":"456\u2013457","author":"Huerta","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0050","doi-asserted-by":"crossref","first-page":"4285","DOI":"10.1021\/ac9001386","article-title":"Fully automated analysis of beta-lactams in bovine milk by online solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry","volume":"81","author":"Kantiani","year":"2009","journal-title":"Anal. Chem."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017038","article-title":"Pyrosequencing of antibiotic-contaminated river sediments reveals high levels of resistance and gene transfer elements","volume":"6","author":"Kristiansson","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0060","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.chemosphere.2008.11.086","article-title":"Antibiotics in the aquatic environment - a review - part I","volume":"75","author":"K\u00fcmmerer","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0065","doi-asserted-by":"crossref","first-page":"9543","DOI":"10.1021\/es202775r","article-title":"Tertiary-treated municipal wastewater is a significant point source of antibiotic resistance genes into Duluth-Superior Harbor","volume":"45","author":"LaPara","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0070","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.envpol.2016.11.059","article-title":"Exploring the contribution of bacteriophages to antibiotic resistance","volume":"220","author":"Lekunberri","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0075","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1086\/432056","article-title":"Hospital and community fluoroquinolone use and resistance in Staphylococcus aureus and Escherichia coli in 17 US hospitals","volume":"41","author":"MacDougall","year":"2005","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078906","article-title":"Prevalence of antibiotic resistance genes and bacterial community composition in a river influenced by a wastewater treatment plant","volume":"8","author":"Marti","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0085","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1093\/gbe\/evu214","article-title":"Extensive horizontal gene transfer during Staphylococcus aureus co-colonization in vivo","volume":"6","author":"McCarthy","year":"2014","journal-title":"Genome Biol. Evol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0090","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1186\/s12864-015-1407-6","article-title":"Investigating the mobilome in clinically important lineages of Enterococcus faecium and Enterococcus faecalis","volume":"16","author":"Mikalsen","year":"2015","journal-title":"BMC Genomics"},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0095","doi-asserted-by":"crossref","first-page":"3753","DOI":"10.1128\/AEM.03080-09","article-title":"Identification of diverse antimicrobial resistance determinants carried on bacterial, plasmid, or viral metagenomes from an activated sludge microbial assemblage","volume":"76","author":"Parsley","year":"2010","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0105","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3389\/fmicb.2013.00138","article-title":"The antibiotic resistance \u201cmobilome\u201d: searching for the link between environment and clinic","volume":"4","author":"Perry","year":"2013","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0110","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.3201\/eid2106.141504","article-title":"KPC and NDM-1 genes in related Enterobacteriaceae strains and plasmids from Pakistan and the United States","volume":"21","author":"Pesesky","year":"2015","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0115","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.envpol.2015.11.035","article-title":"Occurrence and persistence of antibiotic resistance genes in river biofilms after wastewater inputs in small rivers","volume":"210","author":"Proia","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0120","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1021\/es403883p","article-title":"Balancing water sustainability and public health goals in the face of growing concerns about antibiotic resistance","volume":"48","author":"Pruden","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0125","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.scitotenv.2013.01.032","article-title":"Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: a review","volume":"447","author":"Rizzo","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0130","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.watres.2014.11.021","article-title":"Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river","volume":"69","author":"Rodriguez-Mozaz","year":"2015","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0135","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1021\/es902893f","article-title":"Identification of antibiotic-resistance-gene molecular signatures suitable as tracers of pristine river, urban, and agricultural sources","volume":"44","author":"Storteboom","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0140","doi-asserted-by":"crossref","first-page":"6710","DOI":"10.1007\/s11356-017-8426-6","article-title":"Real-time PCR assays for the detection and quantification of carbapenemase genes (blaKPC, blaNDM and blaOXA-48) in environmental samples","volume":"24","author":"Subirats","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0145","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/jac\/dkq455","article-title":"Host range of enterococcal vanA plasmids among Gram-positive intestinal bacteria","volume":"66","author":"Werner","year":"2011","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jac\/dkw385","article-title":"Role of cephalosporins in the era of Clostridium difficile infection","volume":"72","author":"Wilcox","year":"2017","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0155","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.chemosphere.2014.02.040","article-title":"Occurrence of antibiotics and antibiotic resistance genes in a sewage treatment plant and its effluent-receiving river","volume":"119","author":"Xu","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0160","doi-asserted-by":"crossref","first-page":"3702","DOI":"10.1016\/j.scitotenv.2009.02.013","article-title":"Wastewater treatment contributes to selective increase of antibiotic resistance among Acinetobacter spp","volume":"407","author":"Zhang","year":"2009","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2017.05.174_bb0165","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1038\/nmicrobiol.2016.270","article-title":"Continental-scale pollution of estuaries with antibiotic resistance genes","volume":"2","author":"Zhu","year":"2017","journal-title":"Nat. Microbiol."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969717312810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969717312810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T08:08:09Z","timestamp":1535789289000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969717312810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":32,"alternative-id":["S0048969717312810"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2017.05.174","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.727663826.793532775","asserted-by":"object"}]},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Contribution of bacteriophage and plasmid DNA to the mobilization of antibiotic resistance genes in a river receiving treated wastewater discharges","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2017.05.174","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}