{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T22:23:39Z","timestamp":1778711019671,"version":"3.51.4"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100005047","name":"Liaoning Natural Science Foundation","doi-asserted-by":"publisher","award":["20170540101"],"award-info":[{"award-number":["20170540101"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.scitotenv.2018.06.315","type":"journal-article","created":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T11:42:06Z","timestamp":1530704526000},"page":"1419-1426","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Toxic effects of copper sulfate on diploid and triploid fin cell lines in Misgurnus anguillicaudatus"],"prefix":"10.1016","volume":"643","author":[{"given":"Yanjie","family":"Qin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuangzhuang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2018.06.315_bb0005","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0048-9697(99)00484-2","article-title":"In vitro response of the brown bullhead catfish BB and rainbow trout (RTG-2) cell lines to benzo [a] pyrene","volume":"247","author":"Araujo","year":"2000","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0010","series-title":"In Vitro Toxic Studies of Cupric Sulfate and Zinc Chloride on Kidney Fin Cell Line in Trachidermus fasciatus","author":"Bai","year":"2015"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0015","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/10641269991319162","article-title":"The physiology and behavior of triploid fishes","volume":"7","author":"Benfey","year":"1999","journal-title":"Rev. Fish. Sci."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0020","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1002\/jsfa.1656","article-title":"Temporal variation in muscle fibre area, gaping, texture, colour and collagen in triploid and diploid Atlantic salmon (Salmo salar L)","volume":"84","author":"Bj\u00f8rnevik","year":"2004","journal-title":"J. Sci. Food Agric."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0025","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0009-2797(01)00287-3","article-title":"Copper ion redox state is critical for its effects on ion transport pathways and met-haemoglobin formation in trout erythrocytes","volume":"139","author":"Bogdanova","year":"2002","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0030","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S1873-0140(05)80005-0","article-title":"Use of fish cell lines in the toxicology and ecotoxicology of fish. Piscine cell lines in environmental toxicology","volume":"6","author":"Bols","year":"2005","journal-title":"Biochem. Mol. Biol. Fish."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0035","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1080\/03067310903033659","article-title":"Genotoxicity assessment of two vineyard pesticides in zebrafish","volume":"90","author":"Bony","year":"2010","journal-title":"Int. J. Environ. Anal. Chem."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0040","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/BF00212430","article-title":"Inhibitory effects of heavy metals on cytochrome P4501A in permanent fish hepatoma cells","volume":"31","author":"Brtischweile","year":"1996","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0045","first-page":"45","article-title":"Susceptibility of diploid and triploid Atlantic salmon, Salmo salar L., to challenge by Renibacterium salmoninarum","volume":"10","author":"Bruno","year":"1990","journal-title":"Bull. Eur. Assoc. Fish Pathol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0050","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.cbpa.2006.05.007","article-title":"The activity of several components of the innate immune system in diploid and triploid turbot","volume":"145","author":"Budi\u00f1o","year":"2006","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"issue":"1","key":"10.1016\/j.scitotenv.2018.06.315_bb0055","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.aquaculture.2010.05.002","article-title":"The effect of triploidy on juvenile Atlantic salmon (Salmo salar) response to varying levels of dietary phosphorus","volume":"306","author":"Burke","year":"2010","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0060","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1042\/bj3130163","article-title":"1,10-Phenanthroline stimulates internucleosomal DNA fragmentation in isolated rat-liver nuclei by promoting the redox activity of endogenous copper ions","volume":"313","author":"Burkitt","year":"1996","journal-title":"Biochem. J."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0065","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.aquaculture.2014.05.032","article-title":"Dietary copper requirements of juvenile large yellow croaker Larimichthys croceus","volume":"432","author":"Cao","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0070","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/hdy.2009.108","article-title":"Transcriptional differences between triploid and diploid Chinook salmon (Oncorhynchus tshawytscha) during live Vibrio anguillarum challenge","volume":"104","author":"Ching","year":"2009","journal-title":"Heredity"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0075","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1095-8312.2004.00330.x","article-title":"Polyploidy in fishes: patterns and processes","volume":"82","author":"Comber","year":"2004","journal-title":"Biol. J. Linn. Soc."},{"issue":"2","key":"10.1016\/j.scitotenv.2018.06.315_bb0080","first-page":"89","article-title":"Acute toxicity of copper sulfate to goldfish and effects on ultrastructure of liver cell","volume":"26","author":"Cong","year":"2005","journal-title":"J. Yangzhou Univ. (Agricultural and Life Science Edition)"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0085","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF00021879","article-title":"Enhancing the productivity of secondary metabolites via induced polyploidy: a review","volume":"87","author":"Dhawan","year":"1996","journal-title":"Euphytica"},{"issue":"3","key":"10.1016\/j.scitotenv.2018.06.315_bb0090","first-page":"81","article-title":"Acute toxicity and genetic toxicity test of lemon on dabryanus","volume":"2","author":"Du","year":"2009","journal-title":"J. Hydroecology"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0095","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1508\/cytologia.65.235","article-title":"Potential genotoxicity in copper sulfate treated mice","volume":"65","author":"Fahmy","year":"2000","journal-title":"Cytologia"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0100","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.ecoenv.2008.04.006","article-title":"Responses of biochemical markers in carp Cyprinus carpio from two field sites in Western Ukraine","volume":"72","author":"Falfushynska","year":"2009","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0105","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.fsi.2012.04.001","article-title":"The effect of triploidy and vaccination on neutrophils and B cells in the peripheral blood and head kidney of 0+ and 1+ Atlantic salmon (Salmo salar L.) post-smolts","volume":"33","author":"Fraser","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0110","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.toxicon.2009.06.019","article-title":"Limited uptake of the cyanobacterial toxin cylindrospermopsin by vero cell","volume":"54","author":"Froscio","year":"2009","journal-title":"Toxicon"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0115","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S1095-6433(02)00245-3","article-title":"The physiological response of diploid and triploid brook trout to exhaustive exercise","volume":"134","author":"Hyndman","year":"2003","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"issue":"5","key":"10.1016\/j.scitotenv.2018.06.315_bb0120","first-page":"556","article-title":"Effect of four kinds of heavy metal on respiration intensity of juvenile Misgurnus anguillicaudatus","volume":"27","author":"Jia","year":"2001","journal-title":"J. Zhejiang Univ."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0125","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.aquatox.2011.08.012","article-title":"Myo-inositol prevents copper-induced oxidative damage and changes inantioxidant capacity in various organs and the enterocytes of juvenile Jian carp (Cyprinus carpio var. Jian)","volume":"105","author":"Jiang","year":"2011","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0130","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.aquatox.2014.12.020","article-title":"Copper exposure induces toxicity to the antioxidant system via the destruction of Nrf2\/ARE signaling and caspase-3-regulated DNA damage in fish muscle: amelioration by myo-inositol","volume":"159","author":"Jiang","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10661-015-4906-7","article-title":"Glutathione S-transferase activities in African catfish injected with b-naphthoflavone: effects of ploidy, gender, dose, and sampling time","volume":"187","author":"Karami","year":"2015","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0140","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jes.2015.05.009","article-title":"Ploidy-, gender-, and dosedependent alteration of selected biomarkers in Clarias gariepinus treated with benzo[a]pyrene","volume":"38","author":"Karami","year":"2015","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0145","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.envpol.2016.05.014","article-title":"Alterations in juvenile diploid and triploid African catfish skin gelatin yield and amino acid composition: effects of chlorpyrifos and butachlor exposures","volume":"215","author":"Karami","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0150","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.envpol.2016.01.055","article-title":"Acute phenanthrene toxicity to juvenile diploid and triploid African catfish (Clarias gariepinus): molecular, biochemical, and histopathological alterations","volume":"212","author":"Karami","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0155","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1006\/fsim.2000.0319","article-title":"The kinetics of the hypoferraemic response and changes in levels of alternative complement activity in diploid and triploid Atlantic salmon, following injection of lipopolysaccharide","volume":"11","author":"Langston","year":"2001","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0160","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.aquaculture.2010.01.029","article-title":"Body size dimorphism of seareared Atlantic salmon (Salmo salar L.): implications for the management of sexual maturation and harvest quality","volume":"301","author":"Leclercq","year":"2010","journal-title":"Aquaculture"},{"issue":"6","key":"10.1016\/j.scitotenv.2018.06.315_bb0165","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0887-2333(01)00090-X","article-title":"In vitro cytotoxicity of the organophosphorus pesticide parathion to FG-9307 cells","volume":"15","author":"Li","year":"2001","journal-title":"Toxicol. in Vitro"},{"issue":"4","key":"10.1016\/j.scitotenv.2018.06.315_bb0170","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1023\/A:1016050911012","article-title":"In vitro cytotoxicity of the organophosphorus insecticide methylparathion to FG-9307, the gill cell line of flounder (Paralichthys olivaceus)","volume":"18","author":"Li","year":"2004","journal-title":"Cell Biol. Toxicol."},{"issue":"5","key":"10.1016\/j.scitotenv.2018.06.315_bb0175","first-page":"107","article-title":"Fish cell culture and its application in the study of virology","volume":"31","author":"Li","year":"2010","journal-title":"Prog. Vet. Med."},{"issue":"1","key":"10.1016\/j.scitotenv.2018.06.315_bb0180","first-page":"150","article-title":"Establishment and characterization of fin cell lines from different ploidy oriental weatherfish, Misgurnus angullicaudatus","volume":"38","author":"Li","year":"2014","journal-title":"Acta Hydrobiologica Sinica"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0185","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s10695-015-0036-y","article-title":"Establishment and characterization of fin cell lines from diploid, triploid, and tetraploid oriental weathrfish (Misgurnus anguillicaudatus)","volume":"41","author":"Li","year":"2015","journal-title":"Fish Physiol. Biochem."},{"issue":"1","key":"10.1016\/j.scitotenv.2018.06.315_bb0190","first-page":"80","article-title":"The establishment and biological characteristics of carp (Cyprinus carpio) analysis","volume":"38","author":"Meng","year":"2005","journal-title":"Exp. Biol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0195","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.etap.2013.02.005","article-title":"Genetoxic effects of 8-hydroxylquinoline in loach (Misgurnus anguillicaudatus) assessed by the micronucleus test, comet assay and RAPD analysis","volume":"35","author":"Nan","year":"2013","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0200","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jes.2015.10.017","article-title":"Distribution and assessment of heavy metals in the surface sediment of Yellow River, China","volume":"39","author":"Nan","year":"2016","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0205","doi-asserted-by":"crossref","DOI":"10.1002\/9780813807379.ch8","article-title":"Clonal lines and chromosome manipulation for aquaculture research and production","volume":"195-216","author":"Nichols","year":"2009","journal-title":"Mol. Res. Aquac."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0210","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.proenv.2011.09.146","article-title":"Heavy metal pollution in surface water of Linglong gold mining area, China","volume":"10","author":"Ning","year":"2011","journal-title":"Procedia Environ Sci"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0215","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1016\/S1054-3139(97)80022-7","article-title":"Comparisons of cultured triploid and diploid Atlantic salmon (Salmo salar L.)","volume":"54","author":"O'Flynn","year":"1997","journal-title":"ICES J. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2008.09.050","article-title":"Acute copper exposure induces oxidative stress and cell death in lateral line hair cells of zebrafish larvae","volume":"1244","author":"Olivari","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0225","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0044-8486(02)00223-5","article-title":"Growth performance and sexual maturation in diploid and triploid Atlantic salmon (Salmo salar L.) in seawater tanks exposed to continuous light or simulated photoperiod","volume":"215","author":"Oppedal","year":"2003","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0230","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0013-9327(77)90047-7","article-title":"The use of biological indicator organisms to monitor trace metal pollution in marine and estuarine environments-a review","volume":"13","author":"Phillips","year":"1977","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0235","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1439-0426.2007.00843.x","article-title":"Flesh qualities and muscle fiber characteristics in triploid and diploid rainbow trout","volume":"23","author":"Poontawee","year":"2007","journal-title":"J. Appl. Ichthyol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0240","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/BF00485721","article-title":"Diploid and tetraploid clonal cells in culture: gene ploidy and synthesis of collagen","volume":"3","author":"Priest","year":"1969","journal-title":"Biochem. Genet."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0245","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/S1001-0742(08)62475-4","article-title":"Ecotoxicological effects of mixed pollutants resulted from e-wastes recycling and bioaccumulation of polybrominated diphenyl ethers in Chinese loach (Misgurnus anguillicaudatus)","volume":"21","author":"Qin","year":"2009","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0250","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.chemosphere.2017.03.098","article-title":"Toxic effects of glyphosate on diploid and triploid fin cell lines from Misgurnus anguillicaudatus","volume":"180","author":"Qin","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0255","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0044-8486(99)00369-5","article-title":"Triploid catarina scallop (Argopecten ventricosus Sowerby II, 1842): growth, gametogenesis, and suppression of functional hermaphroditism","volume":"186","author":"Ruiz-Verdugo","year":"2000","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0260","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ecoenv.2013.12.014","article-title":"First evidence of fish genotoxicity induced by heavy metals from landfill leachates: the advantage of using the RAPD-PCR technique","volume":"101","author":"Salem","year":"2014","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0265","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.anireprosci.2015.12.002","article-title":"Effects of triploidy induction on physiological and immunological characteristics of rainbow trout (Oncorhynchus mykiss) at early developmental stages (fertilized eggs, eyed eggs and fry)","volume":"165","author":"Salimian","year":"2016","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0270","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.scitotenv.2012.06.058","article-title":"Metal accumulation and oxidative stress biomarkers in octopus (Octopus vulgaris) from Northwest Atlantic","volume":"433","author":"Semedo","year":"2012","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0275","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S1001-6279(14)60051-2","article-title":"Geoaccumulation and distribution of heavy metals in the urban river sediment","volume":"29","author":"Shafie","year":"2014","journal-title":"Int. J. Sediment Res."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0280","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.aquaculture.2010.07.021","article-title":"Effects of dietary copper sources and levels on performance, copper status, plasma antioxidant activities and relative copper bioavailability in Carassius auratus gibelio","volume":"308","author":"Shao","year":"2010","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0285","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/etc.5620150323","article-title":"Effects of water pH on copper toxicity to early life stages of the common carp (Cyprinus carpio)","volume":"15","author":"Stouthart","year":"1996","journal-title":"Environ. Toxicol. Chem."},{"issue":"3","key":"10.1016\/j.scitotenv.2018.06.315_bb0290","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1080\/15376520590945621","article-title":"In vitro cytotoxicity of the organotin compound bis-(trin-butyltin)oxide to FG cells","volume":"15","author":"Su","year":"2005","journal-title":"Toxicol. Mech. Methods"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0295","series-title":"Three Strains of Fish Cell Lines Established and Susceptibility of Fish Cell Lines and Twelve Strains of Heavy Metal Toxicity","author":"Tan","year":"2012"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0300","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.tiv.2007.08.020","article-title":"Comparative evaluation of the cytotoxicity sensitivity of six fish cell lines to four heavy metals in vitro","volume":"22","author":"Tan","year":"2008","journal-title":"Toxicol. in Vitro"},{"issue":"2","key":"10.1016\/j.scitotenv.2018.06.315_bb0305","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1021\/es303505z","article-title":"Predicting fish acute toxicity using a fish gill cell line-based toxicity assay","volume":"47","author":"Tanneberger","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0310","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.ygcen.2007.02.029","article-title":"The influence of ploidy on saltwater adaptation, acute stress response and immune function following seawater transfer in non-smolting rainbow trout","volume":"152","author":"Taylor","year":"2007","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0315","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.aquaculture.2013.06.004","article-title":"Ploidy and family effects on Atlantic salmon (Salmo salar) growth, deformity and harvest quality during a full commercial production cycle","volume":"410-411","author":"Taylor","year":"2013","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0320","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.aquaculture.2014.05.014","article-title":"Triploid Atlantic salmon growth is negatively affected by communal ploidy rearing during seawater grow-out in tanks","volume":"432","author":"Taylor","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0325","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ecoenv.2014.01.018","article-title":"In vitro effect of cadmium and copper on separated blood leukocytes of Dicentrarchus labrax","volume":"102","author":"Vazzana","year":"2014","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0330","first-page":"572","article-title":"Heavy metal and growth hormone pathways in metallothionein regulation in fish RTH-149 cell line","volume":"149","author":"Vergani","year":"2009","journal-title":"Comp. Biochem. Physiol. C"},{"issue":"4","key":"10.1016\/j.scitotenv.2018.06.315_bb0335","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s10695-010-9402-y","article-title":"Development and characterization of a new marine fish cell line from turbot (Scophthalmus maximus)","volume":"36","author":"Wang","year":"2010","journal-title":"Fish Physiol. Biochem."},{"issue":"1","key":"10.1016\/j.scitotenv.2018.06.315_bb0340","first-page":"173","article-title":"Toxic effects of potassium dichromate on loach fin cell lines with different ploidies in vitro","volume":"24","author":"Wu","year":"2017","journal-title":"J. Fish. Sci. China"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0345","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.etap.2016.05.030","article-title":"Toxic effects of imidacloprid on adult loach (Misgurnus anguillicaudatus)","volume":"45","author":"Xia","year":"2016","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0350","first-page":"308","article-title":"In vitro cytotoxicity test of monosultap using different ploidy loach fin cell lines","volume":"3","author":"Xiang","year":"2016","journal-title":"Asian J. Ecotoxicol."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0355","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.chemosphere.2009.10.022","article-title":"Sublethal exposure of heavy metals induces micronuclei in fish, Channa punctata","volume":"77","author":"Yadav","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0360","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.foodchem.2005.09.020","article-title":"Heavy metal levels in two fish species Leuciscus cephalus and Lepomis gibbosus","volume":"100","author":"Yilmaz","year":"2007","journal-title":"Food Chem."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0365","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.chemosphere.2015.07.060","article-title":"Heavy metal pollution in the surface water of the Yangtze Estuary: a 5-year follow-up study","volume":"138","author":"Yin","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0370","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.marpolbul.2012.03.023","article-title":"Role of living environments in the accumulation characteristics of heavy metals in fishes and crabs in the Yangtze River Estuary, China","volume":"64","author":"Zhao","year":"2012","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.scitotenv.2018.06.315_bb0375","doi-asserted-by":"crossref","first-page":"105","DOI":"10.33549\/physiolres.930000.50.105","article-title":"Activities of superoxide dismutase and catalase in erythrocytes and plasma transaminases of goldfish (Carassius auratus gibelio Bloch.) exposed to cadmium","volume":"50","author":"Zikic","year":"2001","journal-title":"Physiol. Res."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896971832391X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896971832391X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,5]],"date-time":"2025-07-05T15:19:20Z","timestamp":1751728760000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004896971832391X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":75,"alternative-id":["S004896971832391X"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2018.06.315","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Toxic effects of copper sulfate on diploid and triploid fin cell lines in Misgurnus anguillicaudatus","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2018.06.315","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}