{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:16:04Z","timestamp":1791090964380,"version":"4.1.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000139","name":"U.S. Environmental Protection Agency","doi-asserted-by":"publisher","award":["R835829"],"award-info":[{"award-number":["R835829"]}],"id":[{"id":"10.13039\/100000139","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.scitotenv.2018.08.346","type":"journal-article","created":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T18:58:40Z","timestamp":1535396320000},"page":"431-439","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":71,"special_numbering":"C","title":["Acetaminophen detoxification in cucumber plants via induction of glutathione S-transferases"],"prefix":"10.1016","volume":"649","author":[{"given":"Chengliang","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacia","family":"Dudley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"McGinnis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Trumble","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Gan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2018.08.346_bb0005","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.jhazmat.2009.04.011","article-title":"Ecotoxicological effects of paracetamol on seed germination and seedling development of wheat (Triticum aestivum L.)","volume":"169","author":"An","year":"2009","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0010","series-title":"Proceedings of the National Academy of Sciences of the United States of America, 201700558","article-title":"Discovery of a widespread metabolic pathway within and among phenolic xenobiotics","author":"Ashrap","year":"2017"},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0015","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1007\/s11356-010-0342-y","article-title":"Effects of acetaminophen in Brassica juncea L. Czern.: investigation of uptake, translocation, detoxification, and the induced defense pathways","volume":"17","author":"Bartha","year":"2010","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0020","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.plantsci.2014.06.001","article-title":"Uptake and metabolism of diclofenac in Typha latifolia-how plants cope with human pharmaceutical pollution","volume":"227","author":"Bartha","year":"2014","journal-title":"Plant Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0025","first-page":"374","article-title":"Xenobiotic-metabolizing enzymes in plants and their role in uptake and biotransformation of veterinary drugs in the environment","volume":"47","author":"B\u00e1rt\u00edkov\u00e1","year":"2015","journal-title":"Drug Metab. Rev."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0030","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.tplants.2016.12.010","article-title":"Pharmaceuticals and personal-care products in plants","volume":"22","author":"Bartrons","year":"2017","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0035","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/0048-3575(87)90068-X","article-title":"Soybean metabolism of chlorimuron ethyl: physiological basis for soybean selectivity","volume":"29","author":"Brown","year":"1987","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0040","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1042\/bj1620099","article-title":"The metabolism of benzyl isothiocyanate and its cysteine conjugate","volume":"162","author":"Br\u00fcsewitz","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0045","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1021\/jf404282y","article-title":"Fate and uptake of pharmaceuticals in soil-plant systems","volume":"62","author":"Carter","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0050","doi-asserted-by":"crossref","first-page":"12509","DOI":"10.1021\/acs.est.5b03468","article-title":"Uptake of pharmaceuticals influences plant development and affects nutrient and hormone homeostases","volume":"49","author":"Carter","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0055","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1002\/ps.4863","article-title":"Fenoxaprop-P-ethyl resistance conferred by cytochrome P450s and target site mutation in Alopecurus japonicus","volume":"74","author":"Chen","year":"2018","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0060","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.scitotenv.2016.03.054","article-title":"Stress-related phenomena and detoxification mechanisms induced by common pharmaceuticals in alfalfa (Medicago sativa L.) plants","volume":"557","author":"Christou","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0065","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S1360-1385(97)01019-4","article-title":"Detoxification of xenobiotics by plants: chemical modification and vacuolar compartmentation","volume":"2","author":"Coleman","year":"1997","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0070","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1017\/S0043174500051742","article-title":"Basis of differential tolerance of two corn hybrids (Zea mays) to metolachlor","volume":"40","author":"Cottingham","year":"1992","journal-title":"Weed Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0075","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.scitotenv.2006.04.010","article-title":"Chronic aquatic environmental risks from exposure to human pharmaceuticals","volume":"367","author":"Crane","year":"2006","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0080","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1104\/pp.010066","article-title":"Induction of glutathione S-transferases in Arabidopsis by herbicide safeners","volume":"130","author":"DeRidder","year":"2002","journal-title":"Plant Physiol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0085","series-title":"Genome Biology 3, reviews3004-1","article-title":"Plant glutathione transferases","author":"Dixon","year":"2002"},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0090","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1469-8137.2008.02446.x","article-title":"Enhancing phytoremediation through the use of transgenics and endophytes","volume":"179","author":"Doty","year":"2008","journal-title":"New Phytol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0095","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1021\/es061651j","article-title":"Chlortetracycline detoxification in maize via induction of glutathione S-transferases after antibiotic exposure","volume":"41","author":"Farkas","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0100","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1021\/es950287d","article-title":"Glutathione conjugation and contaminant transformation","volume":"30","author":"Field","year":"1996","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0105","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.envpol.2016.12.022","article-title":"Diclofenac in Arabidopsis cells: rapid formation of conjugates","volume":"222","author":"Fu","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0110","doi-asserted-by":"crossref","first-page":"6071","DOI":"10.1021\/acs.est.6b06266","article-title":"Direct conjugation of emerging contaminants in Arabidopsis: indication for an overlooked risk in plants?","volume":"51","author":"Fu","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0115","doi-asserted-by":"crossref","first-page":"5001","DOI":"10.1073\/pnas.96.9.5001","article-title":"Pathways of As (III) detoxification in Saccharomyces cerevisiae","volume":"96","author":"Ghosh","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0120","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1111\/j.1365-3040.2010.02169.x","article-title":"Co-occurring increases of calcium and organellar reactive oxygen species determine differential activation of antioxidant and defense enzymes in Ulva compressa (Chlorophyta) exposed to copper excess","volume":"33","author":"Gonzalez","year":"2010","journal-title":"Plant Cell Environ."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0125","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/0031-9422(79)80005-9","article-title":"Purification and properties of a glutathione-S-transferase from corn which conjugates s-triazine herbicides","volume":"18","author":"Guddewar","year":"1979","journal-title":"Phytochemistry"},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0130","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.scitotenv.2013.12.008","article-title":"Occurrence and fate of antibiotic, analgesic\/anti-inflammatory, and antifungal compounds in five wastewater treatment processes","volume":"473","author":"Guerra","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0135","doi-asserted-by":"crossref","first-page":"4576","DOI":"10.1021\/acs.est.7b00458","article-title":"Metabolism of ibuprofen by Phragmites australis: uptake and phytodegradation","volume":"51","author":"He","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0140","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/s11356-008-0095-z","article-title":"Metabolism of acetaminophen (paracetamol) in plants-two independent pathways result in the formation of a glutathione and a glucose conjugate","volume":"16","author":"Huber","year":"2009","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0145","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jhazmat.2012.10.023","article-title":"Metabolism of diclofenac in plants-hydroxylation is followed by glucose conjugation","volume":"243","author":"Huber","year":"2012","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0150","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1111\/j.1469-8137.2012.04111.x","article-title":"Cellular glutathione redox homeostasis plays an important role in the brassinosteroid-induced increase in CO2 assimilation in Cucumis sativus","volume":"194","author":"Jiang","year":"2012","journal-title":"New Phytol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0155","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1614\/WS-D-10-00120.1","article-title":"Selection of a sunflower line with multiple herbicide tolerance that is reversed by the P450 inhibitor malathion","volume":"59","author":"Kaspar","year":"2011","journal-title":"Weed Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0160","doi-asserted-by":"crossref","first-page":"3498","DOI":"10.1016\/j.watres.2008.04.026","article-title":"The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK","volume":"42","author":"Kasprzyk-Hordern","year":"2008","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0165","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1007\/s11626-011-9457-9","article-title":"Hepatoprotective activity of Tribulus terrestris extract against acetaminophen-induced toxicity in a freshwater fish (Oreochromis mossambicus)","volume":"47","author":"Kavitha","year":"2011","journal-title":"In Vitro Cellular & Developmental Biology"},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0170","doi-asserted-by":"crossref","first-page":"10959","DOI":"10.1021\/acs.est.5b02749","article-title":"Rapid phytotransformation of benzotriazole generates synthetic tryptophan and auxin analogs in Arabidopsis","volume":"49","author":"Lefevre","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0175","doi-asserted-by":"crossref","first-page":"10797","DOI":"10.1021\/es3028378","article-title":"Metabolization of the bacteriostatic agent triclosan in edible plants and its consequences for plant uptake assessment","volume":"46","author":"Macherius","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0180","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0168-9452(90)90114-4","article-title":"Correlation between CuZn superoxide dismutase and glutathione reductase, and environmental and xenobiotic stress tolerance in maize inbreds","volume":"69","author":"Malan","year":"1990","journal-title":"Plant Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0185","doi-asserted-by":"crossref","first-page":"9325","DOI":"10.1021\/es5017894","article-title":"Irrigation of root vegetables with treated wastewater: evaluating uptake of pharmaceuticals and the associated human health risks","volume":"48","author":"Malchi","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0190","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1146\/annurev.arplant.47.1.127","article-title":"The functions and regulation of glutathione S-transferases in plants","volume":"47","author":"Marrs","year":"1996","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0195","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.envpol.2016.09.074","article-title":"Metabolism of ibuprofen in higher plants: a model Arabidopsis thaliana cell suspension culture system","volume":"220","author":"Marsik","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0200","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1104\/pp.124.3.1105","article-title":"A genomics approach to the comprehensive analysis of the glutathione S-transferase gene family in soybean and maize","volume":"124","author":"McGonigle","year":"2000","journal-title":"Plant Physiol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0205","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1021\/acs.est.5b01546","article-title":"Root uptake of pharmaceuticals and personal care product ingredients","volume":"50","author":"Miller","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0210","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.ecoenv.2014.05.027","article-title":"Toxic potential of paracetamol to freshwater organisms: a headache to environmental regulators?","volume":"107","author":"Nunes","year":"2014","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0215","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/S0021-9258(19)75735-4","article-title":"Mechanisms of acetaminophen oxidation to N-acetyl-P-benzoquinone imine by horseradish peroxidase and cytochrome P450","volume":"262","author":"Potter","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0220","doi-asserted-by":"crossref","first-page":"6100","DOI":"10.1021\/acs.est.6b06485","article-title":"Extensive transformation of the pharmaceutical carbamazepine following uptake into intact tomato plants","volume":"51","author":"Riemenschneider","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0225","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/0968-0004(92)90507-6","article-title":"Plant metabolism of xenobiotics","volume":"17","author":"Sandermann","year":"1992","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0230","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/15226510208500086","article-title":"Conjugating enzymes involved in xenobiotic metabolism of organic xenobiotics in plants","volume":"4","author":"Schr\u00f6der","year":"2002","journal-title":"International Journal of Phytoremediation"},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0235","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.plantsci.2009.11.002","article-title":"Jasmonic acid regulates ascorbate and glutathione metabolism in Agropyron cristatum leaves under water stress","volume":"178","author":"Shan","year":"2010","journal-title":"Plant Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0240","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1111\/nph.12597","article-title":"Nitrate reductase-mediated early nitric oxide burst alleviates oxidative damage induced by aluminum through enhancement of antioxidant defenses in roots of wheat (Triticum aestivum)","volume":"201","author":"Sun","year":"2014","journal-title":"New Phytol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0245","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.envpol.2017.11.041","article-title":"Pharmaceutical and personal care products-induced stress symptoms and detoxification mechanisms in cucumber plants","volume":"234","author":"Sun","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0250","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.tplants.2003.11.009","article-title":"Vacuolar compartmentalization: a second-generation approach to engineering plants for phytoremediation","volume":"9","author":"Tong","year":"2004","journal-title":"Trends Plant Sci."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0255","series-title":"EPA 712\u2013C\u201396-154. Washington, DC","article-title":"Ecological effects testguidelines (OPPTS 850.4200): Seed germination\/root elongationtoxicity test","author":"U.S. Environmental Protection Agency","year":"1996"},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0260","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.pbi.2009.05.001","article-title":"Mechanisms to cope with arsenic or cadmium excess in plants","volume":"12","author":"Verbruggen","year":"2009","journal-title":"Curr. Opin. Plant Biol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0265","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1042\/bj3570065","article-title":"Glutathione S-transferases as antioxidant defence agents confer pyrethroid resistance in Nilaparvata lugens","volume":"357","author":"Vontas","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0270","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.chemosphere.2010.02.020","article-title":"The different responses of glutathione-dependent detoxification pathway to fungicide chlorothalonil and carbendazim in tomato leaves","volume":"79","author":"Wang","year":"2010","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0275","doi-asserted-by":"crossref","first-page":"11286","DOI":"10.1021\/es502868k","article-title":"Treated wastewater irrigation: uptake of pharmaceutical and personal care products by common vegetables under field conditions","volume":"48","author":"Wu","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2018.08.346_bb0280","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1093\/jxb\/eri319","article-title":"Nitric oxide is involved in abscisic acid-induced antioxidant activities in Stylosanthes guianensis","volume":"56","author":"Zhou","year":"2005","journal-title":"J. Exp. Bot."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969718333175?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969718333175?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T20:06:05Z","timestamp":1758657965000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969718333175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":56,"alternative-id":["S0048969718333175"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2018.08.346","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acetaminophen detoxification in cucumber plants via induction of glutathione S-transferases","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2018.08.346","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}