{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:50:08Z","timestamp":1792626608105,"version":"4.5.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,2,14]],"date-time":"2020-02-14T00:00:00Z","timestamp":1581638400000},"content-version":"am","delay-in-days":289,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000139","name":"U.S. Environmental Protection Agency","doi-asserted-by":"publisher","award":["DBI-1266377"],"award-info":[{"award-number":["DBI-1266377"]}],"id":[{"id":"10.13039\/100000139","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006545","name":"NIMHD","doi-asserted-by":"publisher","award":["2G12MD007592"],"award-info":[{"award-number":["2G12MD007592"]}],"id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"USDA","doi-asserted-by":"publisher","award":["2016-67021-24985"],"award-info":[{"award-number":["2016-67021-24985"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"NSF","doi-asserted-by":"publisher","award":["CHE-0840525"],"award-info":[{"award-number":["CHE-0840525"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"NSF","doi-asserted-by":"publisher","award":["DBI-1429708"],"award-info":[{"award-number":["DBI-1429708"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"NSF","doi-asserted-by":"publisher","award":["EEC-1449500"],"award-info":[{"award-number":["EEC-1449500"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.scitotenv.2019.02.029","type":"journal-article","created":{"date-parts":[[2019,2,9]],"date-time":"2019-02-09T20:07:17Z","timestamp":1549742837000},"page":"100-106","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Uptake, transport, and effects of nano-copper exposure in zucchini (Cucurbita pepo)"],"prefix":"10.1016","volume":"665","author":[{"given":"Carlos","family":"Tamez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Hernandez-Molina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose A.","family":"Hernandez-Viezcas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9467-0536","authenticated-orcid":false,"given":"Jorge L.","family":"Gardea-Torresdey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2019.02.029_bb0005","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1080\/01904167.2015.1044012","article-title":"Growth and enzymatic activity of maize (Zea mays L.) plant: solution culture test for copper dioxide nano particles","volume":"39","author":"Adhikari","year":"2016","journal-title":"J. Plant Nutr."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0010","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.envres.2015.02.019","article-title":"Nanoscale copper in the soil\u2013plant system \u2013 toxicity and underlying potential mechanisms","volume":"138","author":"Anjum","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0015","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1016\/j.scitotenv.2017.05.095","article-title":"Physiological and biochemical effects of nanoparticulate copper, bulk copper, copper chloride, and kinetin in kidney bean (Phaseolus vulgaris) plants","volume":"599\u2013600","author":"Apodaca","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0020","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.scitotenv.2015.11.143","article-title":"Effects of uncoated and citric acid coated cerium oxide nanoparticles, bulk cerium oxide, cerium acetate, and citric acid on tomato plants","volume":"563\u2013564","author":"Barrios","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0025","series-title":"Plant Micronutrient Use Efficiency","first-page":"181","article-title":"Chapter 10 - oxidative stress in relation with micronutrient deficiency or toxicity","author":"Blasco","year":"2018"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0030","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.plaphy.2016.04.008","article-title":"Zinc, copper, or cerium accumulation from metal oxide nanoparticles or ions in sweet potato: yield effects and projected dietary intake from consumption","volume":"110","author":"Bradfield","year":"2017","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0035","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s11099-015-0167-5","article-title":"Effect of copper oxide nanoparticles on growth, morphology, photosynthesis, and antioxidant response in Oryza sativa","volume":"54","author":"Da Costa","year":"2016","journal-title":"Photosynthetica"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0040","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.plaphy.2016.04.024","article-title":"Interaction of metal oxide nanoparticles with higher terrestrial plants: physiological and biochemical aspects","volume":"110","author":"Du","year":"2017","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0045","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.scitotenv.2017.11.042","article-title":"Differential effects of copper nanoparticles\/microparticles in agronomic and physiological parameters of oregano (Origanum vulgare)","volume":"618","author":"Du","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0050","author":"Food and Argiculture Organization"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0055","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0168-9452(96)04528-1","article-title":"Effect of heavy metal ion excess on sunflower leaves: evidence for involvement of oxidative stress","volume":"121","author":"Gallego","year":"1996","journal-title":"Plant Sci."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0060","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/jpln.200625161","article-title":"Boron in plants and animals: is there a role beyond cell-wall structure?","volume":"170","author":"Goldbach","year":"2007","journal-title":"J. Plant Nutr. Soil Sci."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0065","first-page":"374","article-title":"Role of zinc in plant nutrition-a review","volume":"3","author":"Hafeez","year":"2013","journal-title":"Am. J. Exp. Agric."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0070","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.jplph.2007.11.002","article-title":"Boron deficiency decreases growth and photosynthesis, and increases starch and hexoses in leaves of citrus seedlings","volume":"165","author":"Han","year":"2008","journal-title":"J. Plant Physiol."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0075","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1080\/15226514.2011.620903","article-title":"Accumulation and phytotoxicity of engineered nanoparticles to Cucurbita pepo","volume":"14","author":"Hawthorne","year":"2012","journal-title":"Int. J. Phytoremediation"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0080","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1039\/C4EM00551A","article-title":"Toxic effects of copper-based nanoparticles or compounds to lettuce (Lactuca sativa) and alfalfa (Medicago sativa)","volume":"17","author":"Hong","year":"2015","journal-title":"Environ. Sci. Processes Impacts"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0085","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0958-1669(95)80024-7","article-title":"Oxidative stress in plants","volume":"6","author":"Inz\u00e9","year":"1995","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0090","doi-asserted-by":"crossref","DOI":"10.1007\/s11051-013-1692-4","article-title":"Global life cycle releases of engineered nanomaterials","volume":"15","author":"Keller","year":"2013","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0095","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.scitotenv.2016.01.063","article-title":"Effect of cobalt ferrite (CoFe2O4) nanoparticles on the growth and development of Lycopersicon lycopersicum (tomato plants)","volume":"550","author":"L\u00f3pez-Moreno","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0100","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.jhazmat.2017.03.008","article-title":"Comparison of the effects of commercial coated and uncoated ZnO nanomaterials and Zn compounds in kidney bean (Phaseolus vulgaris) plants","volume":"332","author":"Medina-Velo","year":"2017","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0105","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1111\/j.1365-313X.2004.02092.x","article-title":"Arabidopsis thaliana plants overexpressing thylakoidal ascorbate peroxidase show increased resistance to Paraquat-induced photooxidative stress and to nitric oxide-induced cell death","volume":"38","author":"Murgia","year":"2004","journal-title":"Plant J."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0110","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1002\/tox.20667","article-title":"Toxicity of silver and copper to Cucurbita pepo: differential effects of nano and bulk-size particles","volume":"27","author":"Musante","year":"2010","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0115","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.scitotenv.2017.04.063","article-title":"Modulation of CuO nanoparticles toxicity to green pea (Pisum sativum Fabaceae) by the phytohormone indole-3-acetic acid","volume":"598","author":"Ochoa","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0120","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.envpol.2014.12.008","article-title":"Translocation and biotransformation of CuO nanoparticles in rice (Oryza sativa L.) plants","volume":"197","author":"Peng","year":"2015","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0125","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jcat.2013.01.025","article-title":"Fenton-like copper redox chemistry revisited: hydrogen peroxide and superoxide mediation of copper-catalyzed oxidant production","volume":"301","author":"Pham","year":"2013","journal-title":"J. Catal."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0130","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S0005-2728(89)80347-0","article-title":"Determination of accurate extinction coefficients and simultaneous equations for assaying chlorophylls a and b extracted with four different solvents: verification of the concentration of chlorophyll standards by atomic absorption spectroscopy","volume":"975","author":"Porra","year":"1989","journal-title":"BBA-Bioenergetics"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0135","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1039\/C7EN00697G","article-title":"Impacts of copper oxide nanoparticles on bell pepper (Capsicum annum L.) plants: a full life cycle study","volume":"5","author":"Rawat","year":"2018","journal-title":"Environ. Sci. Nano"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0140","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.aquatox.2009.10.002","article-title":"Effect of core-shell copper oxide nanoparticles on cell culture morphology and photosynthesis (photosystem II energy distribution) in the green alga, Chlamydomonas reinhardtii","volume":"96","author":"Saison","year":"2010","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0145","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1021\/acs.jafc.7b05921","article-title":"Application of copper-chitosan nanoparticles stimulate growth and induce resistance in finger millet (Eleusine coracana Gaertn.) plants against blast disease","volume":"66","author":"Sathiyabama","year":"2018","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0150","article-title":"Plant micronutrients","author":"Sharma","year":"2007","journal-title":"Exp. Agric."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0155","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.chemosphere.2013.05.044","article-title":"Impact of nano-CuO stress on rice (Oryza sativa L.) seedlings","volume":"93","author":"Shaw","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0160","doi-asserted-by":"crossref","first-page":"9473","DOI":"10.1021\/es901695c","article-title":"Assay-dependent phytotoxicity of nanoparticles to plants","volume":"43","author":"Stampoulis","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0165","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s11671-017-1839-9","article-title":"Effect of zinc and copper nanoparticles on drought resistance of wheat seedlings","volume":"12","author":"Taran","year":"2017","journal-title":"Nanoscale Res. Lett."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0170","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.plaphy.2016.09.013","article-title":"Physiological and biochemical responses of sunflower (Helianthus annuus L.) exposed to nano-CeO2 and excess boron: modulation of boron phytotoxicity","volume":"110","author":"Tassi","year":"2017","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0175","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jhazmat.2013.11.067","article-title":"Exposure studies of core\u2013shell Fe\/Fe3O4 and Cu\/CuO NPs to lettuce (Lactuca sativa) plants: are they a potential physiological and nutritional hazard?","volume":"267","author":"Trujillo-Reyes","year":"2014","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0180","doi-asserted-by":"crossref","first-page":"112","DOI":"10.12692\/ijb\/6.4.112-117","article-title":"Effect of silver, copper and iron nanoparticles on wheat germination","volume":"6","author":"Yasmeen","year":"2015","journal-title":"Int. J. Biosci."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0185","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1080\/01904169809365493","article-title":"Micronutrient deficiency changes activities of superoxide dismutase and ascorbate peroxidase in tobacco plants","volume":"21","author":"Yu","year":"1998","journal-title":"J. Plant Nutr."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0190","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1021\/es5060226","article-title":"Monitoring the environmental effects of CeO2 and ZnO nanoparticles through the life cycle of corn (Zea mays) plants and in situ \u03bc-XRF mapping of nutrients in kernels","volume":"49","author":"Zhao","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0195","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1021\/acs.est.5b05011","article-title":"1H NMR and GC-MS based metabolomics reveal defense and detoxification mechanism of cucumber plant under nano-Cu stress","volume":"50","author":"Zhao","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0200","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1039\/C5EM00329F","article-title":"Copper nanoparticles\/compounds impact agronomic and physiological parameters in cilantro (Coriandrum sativum)","volume":"17","author":"Zuverza-Mena","year":"2015","journal-title":"Environ. Sci. Processes Impacts"},{"key":"10.1016\/j.scitotenv.2019.02.029_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.plaphy.2016.05.037","article-title":"Exposure of engineered nanomaterials to plants: insights into the physiological and biochemical responses-a review","author":"Zuverza-Mena","year":"2017","journal-title":"Plant Physiol. Biochem."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896971930508X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896971930508X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T08:17:28Z","timestamp":1758701848000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004896971930508X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":41,"alternative-id":["S004896971930508X"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2019.02.029","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Uptake, transport, and effects of nano-copper exposure in zucchini (Cucurbita pepo)","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2019.02.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}