{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T11:09:51Z","timestamp":1791544191727,"version":"4.3.4"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000139","name":"U.S. Environmental Protection Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000139","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003303","name":"Research Foundation for Health and Environmental Effects","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100003303","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.scitotenv.2019.135772","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T07:20:24Z","timestamp":1575271224000},"page":"135772","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":66,"special_numbering":"C","title":["Health effects from freshly emitted versus oxidatively or photochemically aged air pollutants"],"prefix":"10.1016","volume":"704","author":[{"given":"Chelsea A.","family":"Weitekamp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Bhave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3070-6704","authenticated-orcid":false,"given":"M. Ian","family":"Gilmour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2019.135772_bb0005","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.tiv.2012.11.017","article-title":"Toxicological analysis of limonene reaction products using an in vitro exposure system","volume":"27","author":"Anderson","year":"2013","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0010","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.5194\/acp-5-2497-2005","article-title":"Modelling the evolution of organic carbon during its gas-phase tropospheric oxidation: development of an explicit model based on a self generating approach","volume":"5","author":"Aumont","year":"2005","journal-title":"Atmos. Chem. Phys."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0015","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1080\/00039896.1972.10666102","article-title":"Cardiovascular status of female beagles exposed to air pollutants","volume":"24","author":"Bloch","year":"1972","journal-title":"Arch. Environ. Occup. Health"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0020","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/0041-008X(73)90027-6","article-title":"Blood rheology of dogs chronically exposed to air pollutants","volume":"25","author":"Bloch","year":"1973","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0025","series-title":"Particulate Matter Air Pollution and Cardiovascular Disease an Update to the Scientific Statement from the American Heart Association. Circulation","first-page":"2331","volume":"121","author":"Brook","year":"2010"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0030","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.tox.2015.07.007","article-title":"Conceptual model for assessing criteria air pollutants in a multipollutant context: a modified adverse outcome pathway approach","volume":"335","author":"Buckley","year":"2015","journal-title":"Toxicology"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0035","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1021\/acs.estlett.8b00256","article-title":"Exposure of lung epithelial cells to Photochemically aged secondary organic aerosol shows increased toxic effects","volume":"5","author":"Chowdhury","year":"2018","journal-title":"Environ Sci Tech Let"},{"issue":"Suppl. 2","key":"10.1016\/j.scitotenv.2019.135772_bb0040","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3109\/08958378.2010.578169","article-title":"Toxicological evaluation of realistic emission source aerosols (TERESA)--power plant studies: assessment of breathing pattern","volume":"23","author":"Diaz","year":"2011","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0045","doi-asserted-by":"crossref","first-page":"288","DOI":"10.3109\/08958378.2012.668572","article-title":"Effects of fresh and aged vehicular exhaust emissions on breathing pattern and cellular responses--pilot single vehicle study","volume":"24","author":"Diaz","year":"2012","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0050","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s11869-012-0179-2","article-title":"Effects of fresh and aged traffic-related particles on breathing pattern, cellular responses, and oxidative stress","volume":"6","author":"Diaz","year":"2013","journal-title":"Air Qual Atmos Hlth"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0055","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/EDE.0b013e3181cc86e8","article-title":"Protecting human health from air pollution: shifting from a single-pollutant to a multipollutant approach","volume":"21","author":"Dominici","year":"2010","journal-title":"Epidemiology"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0060","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1289\/ehp.7022","article-title":"Effects of 1,3-butadiene, isoprene, and their photochemical degradation products on human lung cells","volume":"112","author":"Doyle","year":"2004","journal-title":"Environ Health Persp"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0065","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.cbi.2006.05.016","article-title":"Atmospheric photochemical transformations enhance 1,3-butadiene-induced inflammatory responses in human epithelial cells: the role of ozone and other photochemical degradation products","volume":"166","author":"Doyle","year":"2007","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0070","first-page":"5065","article-title":"Gaseous VOCs rapidly modify particulate matter and its biological effects - part 1: simple VOCs and model PM","volume":"12","author":"Ebersviller","year":"2012","journal-title":"Atmospheric Chemistry and Physics Discussions"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0075","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1289\/ehp.8132","article-title":"Health effects of a mixture of indoor air volatile organics, their ozone oxidation products, and stress","volume":"113","author":"Fiedler","year":"2005","journal-title":"Environ Health Persp"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0080","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1021\/es902261m","article-title":"Cellular responses after exposure of lung cell cultures to secondary organic aerosol particles","volume":"44","author":"Gaschen","year":"2010","journal-title":"Environ Sci Technol"},{"issue":"Suppl. 2","key":"10.1016\/j.scitotenv.2019.135772_bb0085","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3109\/08958378.2010.563804","article-title":"Toxicological evaluation of realistic emission source aerosols (TERESA)-power plant studies: assessment of cellular responses","volume":"23","author":"Godleski","year":"2011","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0090","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1080\/15287394.2013.838915","article-title":"Adjuvant and inflammatory effects in mice after subchronic inhalation of allergen and ozone-initiated limonene reaction products","volume":"76","author":"Hansen","year":"2013","journal-title":"J Toxicol Env Heal A"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0095","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1080\/1547691X.2016.1195462","article-title":"Limonene and its ozone-initiated reaction products attenuate allergic lung inflammation in mice","volume":"13","author":"Hansen","year":"2016","journal-title":"J. Immunotoxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0100","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0165-7992(83)90006-4","article-title":"Mutagenicity of coal-pyrolyzed products and their photochemical reaction products with nitrogen oxides in Salmonella typhimurium TA98 and TA100","volume":"122","author":"Hirayama","year":"1983","journal-title":"Mutat. Res."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0105","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1080\/00039896.1966.10664432","article-title":"Biological effects of atmospheres contaminated by auto exhaust","volume":"12","author":"Hueter","year":"1966","journal-title":"Arch. Environ. Occup. Health"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0110","first-page":"455","article-title":"Morphometric and morphologic evaluation of pulmonary lesions in beagle dogs chronically exposed to high ambient levels of air pollutants","volume":"38","author":"Hyde","year":"1978","journal-title":"Lab. Investig."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0115","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1021\/tx0503597","article-title":"Exposure of BEAS-2B cells to secondary organic aerosol coated on magnetic nanoparticles","volume":"19","author":"Jang","year":"2006","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0120","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1021\/es00125a008","article-title":"Mutagenic changes in dilute wood smoke as it ages and reacts with ozone and nitrogen-dioxide - an outdoor chamber study","volume":"18","author":"Kamens","year":"1984","journal-title":"Environmental Science & Technology"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0125","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1289\/ehp.1002784","article-title":"Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosol","volume":"119","author":"Kipen","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0130","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1021\/es00147a009","article-title":"Wood smoke: measurement of the mutagenic activities of its gas- and particulate-phase photooxidation products","volume":"20","author":"Kleindienst","year":"1986","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0135","doi-asserted-by":"crossref","first-page":"3039","DOI":"10.1016\/0960-1686(92)90294-U","article-title":"The photo-oxidation of automobile emissions: measurements of the transformation products and their mutagenic activity","volume":"26","author":"Kleindienst","year":"1992","journal-title":"Atmos. Environ. Part A"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0140","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s00420-003-0502-1","article-title":"Changes in eye blink frequency as a measure of trigeminal stimulation by exposure to limonene oxidation products, isoprene oxidation products and nitrate radicals","volume":"77","author":"Kleno","year":"2004","journal-title":"Int. Arch. Occup. Environ. Health"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0145","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1016\/j.atmosenv.2008.01.003","article-title":"Chemistry of secondary organic aerosol: formation and evolution of low-volatility organics in the atmosphere","volume":"42","author":"Kroll","year":"2008","journal-title":"Atmos. Environ."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0150","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s11869-012-0177-4","article-title":"Effects of fresh and aged vehicular particulate emissions on blood pressure in normal adult male rats","volume":"6","author":"Lamoureux","year":"2013","journal-title":"Air Qual Atmos Hlth"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0155","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/S0140-6736(17)32345-0","article-title":"The Lancet commission on pollution and health","volume":"391","author":"Landrigan","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0160","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1097\/01.jom.0000183338.95778.f0","article-title":"Nasal effects of a mixture of volatile organic compounds and their ozone oxidation products","volume":"47","author":"Laumbach","year":"2005","journal-title":"J. Occup. Environ. Med."},{"issue":"Suppl. 2","key":"10.1016\/j.scitotenv.2019.135772_bb0165","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3109\/08958378.2011.601433","article-title":"Cardiac and pulmonary oxidative stress in rats exposed to realistic emissions of source aerosols","volume":"23","author":"Lemos","year":"2011","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0170","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1080\/00039896.1974.10666541","article-title":"Long-term exposure to auto exhaust and other pollutant mixtures: effects on pulmonary function in the beagle","volume":"29","author":"Lewis","year":"1974","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0175","doi-asserted-by":"crossref","first-page":"596","DOI":"10.12688\/f1000research.14836.2","article-title":"Diurnal variation in the proinflammatory activity of urban fine particulate matter (PM 2.5) by in vitro assays","volume":"7","author":"Lovett","year":"2018","journal-title":"F1000Research"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0180","doi-asserted-by":"crossref","first-page":"309","DOI":"10.3109\/08958378.2013.782080","article-title":"The effects of \u03b1-pinene versus toluene-derived secondary organic aerosol exposure on the expression of markers associated with vascular disease","volume":"25","author":"Lund","year":"2013","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0185","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/0004-6981(67)90026-1","article-title":"Lead from auto exhaust: effect on mouse bone lead concentration","volume":"1","author":"Lutmer","year":"1967","journal-title":"Atmospheric Environment (1967)"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0190","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1006\/taap.2000.9024","article-title":"Effect of ozone on diesel exhaust particle toxicity in rat lung","volume":"168","author":"Madden","year":"2000","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0195","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3109\/08958370903148114","article-title":"Cardiopulmonary response to inhalation of biogenic secondary organic aerosol","volume":"22","author":"McDonald","year":"2010","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0200","doi-asserted-by":"crossref","first-page":"689","DOI":"10.3109\/08958378.2012.712164","article-title":"Cardiopulmonary response to inhalation of secondary organic aerosol derived from gas-phase oxidation of toluene","volume":"24","author":"McDonald","year":"2012","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0205","first-page":"66","article-title":"Effects on animals of exposure to auto exhaust","volume":"7","author":"Murphy","year":"1963","journal-title":"Arch. Environ. Occup. Health"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0210","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1513\/AnnalsATS.201706-478MG","article-title":"Toxic and genomic influences of inhaled nanomaterials as a basis for predicting adverse outcome","volume":"15","author":"Nymark","year":"2018","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0215","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0013-9351(76)90039-6","article-title":"Collagen and prolyl hydroxylase levels in lungs of beagles exposed to air pollutants","volume":"12","author":"Orthoefer","year":"1976","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0220","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3109\/08958378.2011.587034","article-title":"Laboratory evaluation of a prototype photochemical chamber designed to investigate the health effects of fresh and aged vehicular exhaust emissions","volume":"23","author":"Papapostolou","year":"2011","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0225","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s11869-012-0178-3","article-title":"Development and characterization of an exposure generation system to investigate the health effects of particles from fresh and aged traffic emissions","volume":"6","author":"Papapostolou","year":"2013","journal-title":"Air Qual Atmos Hlth"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0230","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1289\/ehp.1003323","article-title":"A toxicogenomic comparison of primary and photochemically altered air pollutant mixtures","volume":"119","author":"Rager","year":"2011","journal-title":"Environ Health Persp"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0235","series-title":"2008 National Emissions Inventory: Review, Analysis and Highlightsed","first-page":"69","author":"Rao","year":"2013"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0240","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.atmosenv.2018.01.052","article-title":"Mutagenic atmospheres resulting from the photooxidation of aromatic hydrocarbon and NOx mixtures","volume":"178","author":"Riedel","year":"2018","journal-title":"Atmos. Environ."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0245","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.envint.2013.08.002","article-title":"The health significance of gas- and particle-phase terpene oxidation products: a review","volume":"60","author":"Rohr","year":"2013","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0250","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1080\/08958370290084575","article-title":"Upper airway and pulmonary effects of oxidation products of (+)-alpha-pinene, d-limonene, and isoprene in BALB\/c mice","volume":"14","author":"Rohr","year":"2002","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0255","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1289\/EHP408","article-title":"Comparison of points of departure for health risk assessment based on high-throughput screening data","volume":"125","author":"Sand","year":"2017","journal-title":"Environ Health Persp"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0260","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1080\/00022470.1959.10467858","article-title":"Eye irritation from irradiated automobile exhaust (effect of irradiation intensity; half-life studies )","volume":"8","author":"Schuck","year":"1959","journal-title":"Journal of the Air Pollution Control Association"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0265","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1080\/08958370490443196","article-title":"Photochemical products in urban mixtures enhance inflammatory responses in lung cells","volume":"1","author":"Sexton","year":"2004","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0270","doi-asserted-by":"crossref","first-page":"196","DOI":"10.5094\/APR.2010.026","article-title":"The development and uses of EPA\u2019s SPECIATE database","volume":"1","author":"Simon","year":"2010","journal-title":"Atmos Pollut Res"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0275","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.cbi.2010.02.044","article-title":"Benzo[a]pyrene exposed to solar-simulated light inhibits apoptosis and augments carcinogenicity","volume":"185","author":"Teranishi","year":"2010","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0280","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1080\/00039896.1969.10666803","article-title":"Long-term exposure to low levels of air pollutants: effects on pulmonary function in the beagle","volume":"19","author":"Vaughan","year":"1969","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0285","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1289\/ehp.01109937","article-title":"Formation of strong airway irritants in mixtures of isoprene\/ozone and isoprene\/ozone\/nitrogen dioxide","volume":"109","author":"Wilkins","year":"2001","journal-title":"Environ Health Persp"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0290","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0378-4274(03)00115-2","article-title":"Upper airway irritation of terpene\/ozone oxidation products (TOPS). Dependence on reaction time, relative humidity and initial ozone concentration","volume":"143","author":"Wilkins","year":"2003","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0295","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2131\/jts.38.71","article-title":"Effects of acute single intranasal instillation of secondary organic aerosol on neurological and immunological biomarkers in the brain and lung of BALB\/c mice","volume":"38","author":"Win-Shwe","year":"2013","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0300","doi-asserted-by":"crossref","first-page":"11286","DOI":"10.3390\/ijerph111111286","article-title":"Effects of diesel engine exhaust origin secondary organic aerosols on novel object recognition ability and maternal behavior in BALB\/C mice","volume":"11","author":"Win-Shwe","year":"2014","journal-title":"Int J Env Res Pub He"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0305","article-title":"Exposure of BALB\/c mice to diesel engine exhaust origin secondary organic aerosol (DE-SOA) during the developmental stages impairs the social behavior in adult life of the males","volume":"9","author":"Win-Shwe","year":"2016","journal-title":"Front Neurosci-Switz"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0310","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1034\/j.1600-0668.2000.010002082.x","article-title":"Formation of strong airway irritants in terpene\/ozone mixtures","volume":"10","author":"Wolkoff","year":"2000","journal-title":"Indoor Air"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0315","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.toxlet.2011.12.008","article-title":"Airway effects of repeated exposures to ozone-initiated limonene oxidation products as model of indoor air mixtures","volume":"209","author":"Wolkoff","year":"2012","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.scitotenv.2019.135772_bb0320","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.1021\/acs.est.8b00613","article-title":"Evaluation of an air quality health index for predicting the mutagenicity of simulated atmospheres","volume":"52","author":"Zavala","year":"2018","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0325","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2018.00261","article-title":"Bridging the data gap from in vitro toxicity testing to chemical safety assessment through computational modeling","volume":"6","author":"Zhang","year":"2018","journal-title":"Front. Public Health"},{"key":"10.1016\/j.scitotenv.2019.135772_bb0330","series-title":"Atmospheric Transformation of Diesel Emissionsed","first-page":"5","author":"Zielinska","year":"2010"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969719357675?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969719357675?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T13:25:42Z","timestamp":1787232342000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969719357675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":66,"alternative-id":["S0048969719357675"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2019.135772","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Health effects from freshly emitted versus oxidatively or photochemically aged air pollutants","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2019.135772","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"135772"}}