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Biol."},{"key":"10.1016\/j.scitotenv.2020.138317_bb0410","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.foodchem.2013.09.128","article-title":"1H NMR-based metabolomics studies on the effect of sesamin in Atlantic salmon (Salmo salar)","volume":"147","author":"Wagner","year":"2014","journal-title":"Food Chem."},{"key":"10.1016\/j.scitotenv.2020.138317_bb0415","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1007\/s11306-015-0789-4","article-title":"Application of NMR-based metabolomics for environmental assessment in the Great Lakes using zebra mussel (Dreissena polymorpha)","volume":"11","author":"Watanabe","year":"2015","journal-title":"Metabolomics"},{"key":"10.1016\/j.scitotenv.2020.138317_bb0420","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1242\/jeb.138.1.17","article-title":"Respiratory and cardiac performance in Lolliguncula brevis (Cephalopoda, Myopsida): the effects of activity, temperature and hypoxia","volume":"138","author":"Wells","year":"1988","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.138317_bb0425","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1002\/glia.20139","article-title":"Glial glutamate transporter expression patterns in brains from multiple mammalian species","volume":"49","author":"Williams","year":"2005","journal-title":"Glia"},{"key":"10.1016\/j.scitotenv.2020.138317_bb0430","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1242\/jeb.01730","article-title":"Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses","volume":"208","author":"Yancey","year":"2005","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.138317_bb0435","doi-asserted-by":"crossref","first-page":"8356","DOI":"10.1021\/jf402749a","article-title":"Metabolic phenotypes associated with high-temperature tolerance of Porphyra haitanensis strains","volume":"61","author":"Ye","year":"2013","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2020.138317_bb0440","doi-asserted-by":"crossref","first-page":"3496","DOI":"10.1021\/jf405668a","article-title":"Strategy of metabolic phenotype modulation in Portunus trituberculatus exposed to low salinity","volume":"62","author":"Ye","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2020.138317_bb0445","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.aquaculture.2016.05.041","article-title":"Acute metabolic response of Portunus trituberculatus to Vibrio alginolyticus infection","volume":"463","author":"Ye","year":"2016","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2020.138317_bb0450","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.aquaculture.2013.03.018","article-title":"The respiration, excretion and biochemical response of the juvenile common Chinese cuttlefish, Sepiella maindroni at different temperatures","volume":"402","author":"Yin","year":"2013","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2020.138317_bb0455","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.ijbiomac.2018.03.036","article-title":"Metabolic responses and arginine kinase expression of juvenile cuttlefish (Sepia pharaonis) under salinity stress","volume":"13","author":"Yin","year":"2018","journal-title":"Int. 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