{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T20:51:52Z","timestamp":1785790312632,"version":"3.56.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000737","name":"University of Exeter","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000737","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.scitotenv.2020.141370","type":"journal-article","created":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T03:13:52Z","timestamp":1595992432000},"page":"141370","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Fluctuating seawater pCO2\/pH induces opposing interactions with copper toxicity for two intertidal invertebrates"],"prefix":"10.1016","volume":"748","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0571-6094","authenticated-orcid":false,"given":"Alice","family":"Wilson-McNeal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Hird","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Hobbs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Nielson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn E.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rod W.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ceri","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2020.141370_bb0005","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/10236244.2012.727235","article-title":"Effects of pH variability on the intertidal isopod, Paradella dianae","volume":"45","author":"Alenius","year":"2012","journal-title":"Mar. Freshw. Behav. Physiol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0010","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1139\/cjz-2018-0198","article-title":"Experimental assessments of marine species sensitivities to ocean acidification and co-stressors: how far have we come?","volume":"97","author":"Baumann","year":"2019","journal-title":"Can. J. Zool."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0015","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.5194\/bg-10-6225-2013","article-title":"Multiple stressors of ocean ecosystems in the 21st century: projections with CMIP5 models","volume":"10","author":"Bopp","year":"2013","journal-title":"Biogeosciences"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0020","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0025","series-title":"Heavy Metals in the Fal Estuary, Cornwall: A Study of Long Term Contamination by Mining Waste and Its Effects on Estuarine Organisms","author":"Bryan","year":"1983"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0030","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0269-7491(92)90099-V","article-title":"Bioavailability, accumulation and effects of heavy metals in sediments with special reference to United Kingdom estuaries: a review","volume":"76","author":"Bryan","year":"1992","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0035","series-title":"Free Radical and Antioxidant Protocols","author":"Camejo","year":"1999"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0040","doi-asserted-by":"crossref","first-page":"9745","DOI":"10.1021\/es502739m","article-title":"Ocean acidification increases copper toxicity to the early life history stages of the polychaete Arenicola marina in artificial seawater","volume":"48","author":"Campbell","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0045","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.aquatox.2019.03.002","article-title":"Seawater acidification increases copper toxicity: a multi-biomarker approach with a key marine invertebrate, the Pacific oyster Crassostrea gigas","volume":"210","author":"Cao","year":"2019","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3354\/meps11852","article-title":"Diurnal fluctuations in CO2and dissolved oxygen concentrations do not provide a refuge from hypoxia and acidification for early-life-stage bivalves","volume":"558","author":"Clark","year":"2016","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0055","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1242\/jeb.015586","article-title":"Post-prandial alkaline tide in freshwater rainbow trout: effects of meal anticipation on recovery from acid-base and ion regulatory disturbances","volume":"211","author":"Cooper","year":"2008","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0060","series-title":"The ABC of Acid-Base Chemistry: The Elements of Physiological Blood-Gas Chemistry for Medical Students and Physicians","author":"Davenport","year":"1974"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0065","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0305-0491(76)90247-9","article-title":"Anaerobic metabolism in bivalvia (Mollusca): characteristics of anaerobic metabolism","volume":"54","author":"de Zwaan","year":"1976","journal-title":"Comp. Biochem. Physiol. Part B Comp. Biochem."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0070","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/0198-0149(90)90004-F","article-title":"Thermodynamics of the dissociation of boric acid in synthetic seawater from 273.15 to 318.15 K","volume":"37","author":"Dickson","year":"1990","journal-title":"Deep Sea Res. Part A, Oceanogr. Res. Pap."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0075","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1016\/0198-0149(87)90021-5","article-title":"A comparison of the equilibrium constants for the dissociation of carbonic acid in seawater media","volume":"34","author":"Dickson","year":"1987","journal-title":"Deep Sea Res. Part A, Oceanogr. Res. Pap."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0080","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jenvrad.2018.04.017","article-title":"Ocean acidification modulates the incorporation of radio-labeled heavy metals in the larvae of the Mediterranean sea urchin Paracentrotus lividus","volume":"190\u2013191","author":"Dorey","year":"2018","journal-title":"J. Environ. Radioact."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0085","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s12237-013-9594-3","article-title":"Is ocean acidification an open-ocean syndrome? Understanding anthropogenic impacts on seawater pH","volume":"36","author":"Duarte","year":"2013","journal-title":"Estuar. Coasts"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0090","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.aquatox.2016.11.014","article-title":"Responses of the sea anemone, Exaiptasia pallida, to ocean acidification conditions and zinc or nickel exposure","volume":"182","author":"Duckworth","year":"2017","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0095","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1093\/icesjms\/fsn048","article-title":"Impacts of ocean acidification on marine fauna and ecosystem processes","volume":"65","author":"Fabry","year":"2008","journal-title":"ICES J. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0105","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1111\/gcb.12485","article-title":"Can variable pH and low oxygen moderate ocean acidification outcomes for mussel larvae?","volume":"20","author":"Frieder","year":"2014","journal-title":"Glob. Chang. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0110","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1007\/s00227-013-2219-3","article-title":"Impacts of ocean acidification on marine shelled molluscs","volume":"160","author":"Gazeau","year":"2013","journal-title":"Mar. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0115","series-title":"Biology of the Integument","first-page":"323","article-title":"Permeability and epidermal transport","author":"Gomme","year":"1984"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0120","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.aquatox.2014.01.027","article-title":"Interactive effects of CO2 and trace metals on the proteasome activity and cellular stress response of marine bivalves Crassostrea virginica and Mercenaria mercenaria","volume":"149","author":"G\u00f6tze","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0125","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.aquatox.2007.03.026","article-title":"Physiology is pivotal for interactions between salinity and acute copper toxicity to fish and invertebrates","volume":"84","author":"Grosell","year":"2007","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0130","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1289\/ehp.02110s5797","article-title":"Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms","volume":"110","author":"Hartwig","year":"2002","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0135","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ajme.2017.09.001","article-title":"First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid","volume":"54","author":"Ighodaro","year":"2018","journal-title":"Alexandria J. Med."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0145","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.aquatox.2013.05.019","article-title":"Short-term acute hypercapnia affects cellular responses to trace metals in the hard clams Mercenaria mercenaria","volume":"140\u2013141","author":"Ivanina","year":"2013","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0150","first-page":"1","article-title":"Ocean acidification refugia in variable environments","volume":"00","author":"Kapsenberg","year":"2019","journal-title":"Glob. Chang. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0155","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1002\/jps.24108","article-title":"In vivo predictive dissolution: transport analysis of the CO2, bicarbonate in vivo buffer system","volume":"103","author":"Krieg","year":"2014","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0160","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/s41558-017-0054-0","article-title":"Diverging seasonal extremes for ocean acidification during the twenty-first century","volume":"8","author":"Kwiatkowski","year":"2018","journal-title":"Nat. Clim. Chang."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0165","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1242\/jeb.204.1.157","article-title":"Oxidative stress, DNA damage and p53 expression in the larvae of Atlantic cod (Gadus morhua) exposed to ultraviolet (290\u2013400 nm) radiation","volume":"204","author":"Lesser","year":"2001","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0170","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.mrgentox.2008.05.008","article-title":"Genotoxic damage in polychaetes: a study of species and cell-type sensitivities","volume":"654","author":"Lewis","year":"2008","journal-title":"Mutat. Res. - Genet. Toxicol. Environ. Mutagen."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0175","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1007\/s00227-012-2081-8","article-title":"Metal contamination increases the sensitivity of larvae but not gametes to ocean acidification in the polychaete Pomatoceros lamarckii (Quatrefages)","volume":"160","author":"Lewis","year":"2013","journal-title":"Mar. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0180","doi-asserted-by":"crossref","DOI":"10.1038\/srep21554","article-title":"Ocean acidification increases copper toxicity differentially in two key marine invertebrates with distinct acid-base responses","volume":"6","author":"Lewis","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0185","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.marchem.2004.12.001","article-title":"Continuous colorimetric determination of trace ammonium in seawater with a long-path liquid waveguide capillary cell","volume":"96","author":"Li","year":"2005","journal-title":"Mar. Chem."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0190","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.cbpc.2014.12.002","article-title":"Acute exposure to waterborne copper inhibits both the excretion and uptake of ammonia in freshwater rainbow trout (Oncorhynchus mykiss)","volume":"168","author":"Lim","year":"2015","journal-title":"Comp. Biochem. Physiol. Part C Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0195","first-page":"83","article-title":"The relationship of copper to DNA damage and damage prevention in humans","volume":"733","author":"Linder","year":"2012","journal-title":"Mutat. Res. - Fundam. Mol. Mech. Mutagen."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0200","first-page":"371","article-title":"Acid-base balance in the sea mussel, Mytilus edulis. III. Effects of environmental hypercapnia on intra- and extracellular acid-base balance","volume":"5","author":"Lindinger","year":"1984","journal-title":"Mar. Biol. Lett"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0205","first-page":"284","article-title":"Fluctuating seawater pH\/pCO2 regimes are more energetically expensive than static pH\/pCO2 levels in the mussel Mytilus edulis","author":"Mangan","year":"2017","journal-title":"Proc. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0210","doi-asserted-by":"crossref","first-page":"20182863","DOI":"10.1098\/rspb.2018.2863","article-title":"Acid\u2013base physiology over tidal periods in the mussel Mytilus edulis: size and temperature are more influential than seawater pH","volume":"286","author":"Mangan","year":"2019","journal-title":"Proc. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0220","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/nature16156","article-title":"Future ocean hypercapnia driven by anthropogenic amplification of the natural CO2 cycle","volume":"529","author":"McNeil","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0225","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.5194\/bg-6-2313-2009","article-title":"Physiological basis for high CO2 tolerance in marine ectothermic animals: pre-adaptation through lifestyle and ontogeny?","volume":"6","author":"Melzner","year":"2009","journal-title":"Biogeosciences"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0230","doi-asserted-by":"crossref","first-page":"109","DOI":"10.3354\/meps293109","article-title":"Effects of long-term moderate hypercapnia on acid-base balance and growth rate in marine mussels Mytilus galloprovincialis","volume":"293","author":"Michaelidis","year":"2005","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0235","doi-asserted-by":"crossref","first-page":"72","DOI":"10.5670\/oceanog.2009.98","article-title":"Effect of ocean acidification on the speciation of metals in seawater","volume":"22","author":"Millero","year":"2009","journal-title":"Oceanography"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0240","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.scitotenv.2015.12.029","article-title":"The effects of arsenic and seawater acidification on antioxidant and biomineralization responses in two closely related Crassostrea species","volume":"545\u2013546","author":"Moreira","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0245","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.aquatox.2019.05.003","article-title":"Ocean acidification buffers the physiological responses of the king ragworm Alitta virens to the common pollutant copper","volume":"212","author":"Nielson","year":"2019","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0250","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/333134a0","article-title":"Quantitative assessment of worldwide contamination of air, water and soils by trace metals","volume":"333","author":"Nriagu","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0255","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.marenvres.2017.12.015","article-title":"Effects of ocean acidification with pCO2 diurnal fluctuations on survival and larval shell formation of Ezo abalone, Haliotis discus hannai","volume":"134","author":"Onitsuka","year":"2018","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0260","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.aquatox.2004.06.003","article-title":"Interactive effects of temperature and copper on immunocompetence and disease susceptibility in mussels (Mytilus edulis)","volume":"69","author":"Parry","year":"2004","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb5005","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jcat.2013.01.025","article-title":"Fenton-like copper redox chemistry revisited: Hydrogen peroxide and superoxide mediation of copper-catalyzed oxidant production","volume":"301","author":"Pham","year":"2013","journal-title":"J. Catal."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0265","series-title":"MS Excel Program Developed for CO2 System Calculations","author":"Pierrot","year":"2006"},{"key":"10.1016\/j.scitotenv.2020.141370_bb0270","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.marpolbul.2015.03.042","article-title":"Metal bioavailability and bioaccumulation in the polychaete Nereis (Alitta) virens (Sars): the effects of site-specific sediment characteristics","volume":"95","author":"Pini","year":"2015","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0275","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1242\/jeb.203.16.2417","article-title":"Modulation of the cost of pHi regulation during metabolic depression: a 31P-NMR study in invertebrate (Sipunculus nudus) isolated muscle","volume":"203","author":"Portner","year":"2000","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0280","doi-asserted-by":"crossref","first-page":"826S","DOI":"10.1093\/ajcn\/88.3.826S","article-title":"Role of copper transporters in copper homeostasis","volume":"88","author":"Prohaska","year":"2008","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0285","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1242\/jeb.02100","article-title":"Tribute to R. G. Boutilier: acid-base transfer across fish gills","volume":"209","author":"Randall","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0290","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.aquatox.2018.07.020","article-title":"Copper and ocean acidification interact to lower maternal investment, but have little effect on adult physiology of the Sydney rock oyster Saccostrea glomerata","volume":"203","author":"Scanes","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0300","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3354\/meps07973","article-title":"Seagrass photosynthesis controls rates of calcification and photosynthesis of calcareous macroalgae in a tropical seagrass meadow","volume":"382","author":"Semesi","year":"2009","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0305","doi-asserted-by":"crossref","first-page":"138001","DOI":"10.1016\/j.scitotenv.2020.138001","article-title":"Diel-cycling seawater acidification and hypoxia impair the physiological and growth performance of marine mussels","volume":"722","author":"Shang","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0310","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/s41598-017-18736-6","article-title":"Biophysical feedbacks mediate carbonate chemistry in coastal ecosystems across spatiotemporal gradients","volume":"8","author":"Silbiger","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0315","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1093\/icesjms\/fsv232","article-title":"Temporal fluctuations in seawater pCO2 may be as important as mean differences when determining physiological sensitivity in natural systems","volume":"73","author":"Small","year":"2016","journal-title":"ICES J. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0320","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0043-1354(71)90049-2","article-title":"Copper\/bicarbonate equilibria in solutions of bicarbonate ion at concentrations similar to those found in natural water","volume":"5","author":"Stiff","year":"1971","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0325","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1021\/acs.est.5b05624","article-title":"Effect of ocean acidification on organic and inorganic speciation of trace metals","volume":"50","author":"Stockdale","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0330","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3389\/fmicb.2012.00204","article-title":"Feedback interactions between trace metal nutrients and phytoplankton in the ocean","volume":"3","author":"Sunda","year":"2012","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0335","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1111\/gcb.12109","article-title":"Food availability outweighs ocean acidification effects in juvenile Mytilus edulis: laboratory and field experiments","volume":"19","author":"Thomsen","year":"2013","journal-title":"Glob. Chang. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0340","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1242\/jeb.139550","article-title":"Ammonia excretion in mytilid mussels is facilitated by ciliary beating","volume":"219","author":"Thomsen","year":"2016","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0345","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1242\/jeb.64.1.45","article-title":"Carbon dioxide combining properties of the blood of the shore crab Carcinus maenas (L): carbon dioxide solubility coefficient and carbonic acid dissociation constants","volume":"64","author":"Truchot","year":"1976","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0350","first-page":"421","article-title":"In vivo effects of copper on the calcium homeostasis mechanisms of mussel gill cell plasma membranes","volume":"113","author":"Viarengo","year":"1996","journal-title":"Comp. Biochem. Physiol. Part C Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb5000","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/j.envpol.2018.09.091","article-title":"Chronic exposure to copper and zinc induces DNA damage in the polychaete Alitta virens and the implications for future toxicity of coastal sites","volume":"243","author":"Watson","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0355","article-title":"Ammonia excretion in aquatic invertebrates: new insights and questions","volume":"221","author":"Weihrauch","year":"2018","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0360","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/nclimate1982","article-title":"Sensitivities of extant animal taxa to ocean acidification","volume":"3","author":"Wittmann","year":"2013","journal-title":"Nat. Clim. Chang."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0365","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0022-0981(86)90265-0","article-title":"Factors affecting short-term variability in sediment pH as a function of marsh elevation in a Virginia mesohaline marsh","volume":"101","author":"Wolaver","year":"1986","journal-title":"J. Exp. Mar. Bio. Ecol."},{"key":"10.1016\/j.scitotenv.2020.141370_bb0370","doi-asserted-by":"crossref","first-page":"18848","DOI":"10.1073\/pnas.0810079105","article-title":"Dynamic patterns and ecological impacts of declining ocean pH in a high-resolution multi-year dataset","volume":"105","author":"Wootton","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969720348993?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969720348993?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T20:24:49Z","timestamp":1785788689000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969720348993"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":72,"alternative-id":["S0048969720348993"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2020.141370","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fluctuating seawater pCO2\/pH induces opposing interactions with copper toxicity for two intertidal invertebrates","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2020.141370","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"141370"}}