{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T13:21:59Z","timestamp":1792934519336,"version":"4.5.0"},"reference-count":100,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100008248","name":"Department of Zoology, University of Otago","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008248","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.scitotenv.2020.141941","type":"journal-article","created":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T03:30:16Z","timestamp":1598671816000},"page":"141941","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Time-cumulative effects of neonicotinoid exposure, heatwaves and food limitation on stream mayfly nymphs: A multiple-stressor experiment"],"prefix":"10.1016","volume":"754","author":[{"given":"Samuel J.","family":"Macaulay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly J.","family":"Hageman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy J.","family":"Piggott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph D.","family":"Matthaei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2020.141941_bb0005","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1603\/EN11188","article-title":"Climate change and temperate zone insects: the tyranny of thermodynamics meets the world of limited resources","volume":"41","author":"Adamo","year":"2012","journal-title":"Environ. Entomol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0010","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1897\/07-015R.1","article-title":"Effects of insecticide exposure on feeding inhibition in mayflies and oligochaetes","volume":"26","author":"Alexander","year":"2007","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0015","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.chemosphere.2015.01.044","article-title":"Combined effects of larval exposure to a heat wave and chlorpyrifos in northern and southern populations of the damselfly Ischnura elegans","volume":"128","author":"Arambourou","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0020","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.envpol.2018.03.004","article-title":"Lethal and sublethal toxicity of neonicotinoid and butenolide insecticides to the mayfly, Hexagenia spp","volume":"238","author":"Bartlett","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0025","doi-asserted-by":"crossref","first-page":"e39","DOI":"10.1002\/ieam.1444","article-title":"More ecological ERA: incorporating natural environmental factors and animal behavior","volume":"9","author":"Bednarska","year":"2013","journal-title":"Integr. Environ. Assess. Manag."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0030","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00244-007-9104-3","article-title":"Potential of 11 pesticides to initiate downstream drift of stream macroinvertebrates","volume":"55","author":"Beketov","year":"2008","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0035","doi-asserted-by":"crossref","first-page":"11039","DOI":"10.1073\/pnas.1305618110","article-title":"Pesticides reduce regional biodiversity of stream invertebrates","volume":"110","author":"Beketov","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0040","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1046\/j.1365-2664.2002.00745.x","article-title":"Linking agricultural practice to insect and bird populations: a historical study over three decades","volume":"39","author":"Benton","year":"2002","journal-title":"J. Appl. Ecol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0045","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1002\/ece3.1403","article-title":"Physiological ecology meets climate change","volume":"5","author":"Bozinovic","year":"2015","journal-title":"Ecology and Evolution"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0050","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF00017485","article-title":"Invertebrate drift \u2014 a review","volume":"166","author":"Brittain","year":"1988","journal-title":"Hydrobiologia"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0055","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1897\/09-108.1","article-title":"Sublethal effects and predator-prey interactions: implications for ecological risk assessment","volume":"28","author":"Brooks","year":"2009","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0060","doi-asserted-by":"crossref","DOI":"10.3389\/fenvs.2019.00059","article-title":"The importance of ecological networks in multiple-stressor research and management","volume":"7","author":"Bruder","year":"2019","journal-title":"Frontiers in Environmental Science"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0065","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.aquatox.2016.07.011","article-title":"Can\u2019t take the heat: temperature-enhanced toxicity in the mayfly Isonychia bicolor exposed to the neonicotinoid insecticide imidacloprid","volume":"178","author":"Camp","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0070","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1002\/etc.3536","article-title":"Comparative chronic toxicity of imidacloprid, clothianidin, and thiamethoxam to Chironomus dilutus and estimation of toxic equivalency factors","volume":"36","author":"Cavallaro","year":"2017","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0075","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1002\/etc.4187","article-title":"Community-level and phenological responses of emerging aquatic insects exposed to 3 neonicotinoid insecticides: an in situ wetland limnocorral approach","volume":"37","author":"Cavallaro","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0080","series-title":"Canadian Environmental Quality Guidelines","author":"CCME","year":"2018"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0085","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s11356-014-3277-x","article-title":"Risks of large-scale use of systemic insecticides to ecosystem functioning and services","volume":"22","author":"Chagnon","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0090","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1242\/jeb.02093","article-title":"Effects of acclimation temperature and cadmium exposure on cellular energy budgets in the marine mollusk Crassostrea virginica: linking cellular and mitochondrial responses","volume":"209","author":"Cherkasov","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0095","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/etc.5620020408","article-title":"Effects of temperature and nutritional state on the acute toxicity of acridine to the calanoid copepod, Diaptomus clavipes Schacht","volume":"2","author":"Cooney","year":"1983","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0100","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1080\/00288330.2000.9516926","article-title":"Thermal tolerances of two stream invertebrates exposed to diumally varying temperature","volume":"34","author":"Cox","year":"2000","journal-title":"N. Z. J. Mar. Freshw. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0105","first-page":"81","article-title":"The sublethal effects of pesticides on beneficial arthropods","volume":"52","author":"Desneux","year":"2007"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0110","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1111\/gcb.13415","article-title":"Exposure to a heat wave under food limitation makes an agricultural insecticide lethal: a mechanistic laboratory experiment","volume":"22","author":"Dinh","year":"2016","journal-title":"Glob. Chang. Biol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0115","series-title":"Aquatic Life Benchmarks and Ecological Risk Assessments for Registered Pesticides","author":"EPA","year":"2018"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0120","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1146\/annurev.physiol.61.1.243","article-title":"Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology","volume":"61","author":"Feder","year":"1999","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0125","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.1002\/etc.3846","article-title":"Comprehensive characterization of the acute and chronic toxicity of the neonicotinoid insecticide thiamethoxam to a suite of aquatic primary producers, invertebrates, and fish","volume":"36","author":"Finnegan","year":"2017","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0130","doi-asserted-by":"crossref","first-page":"864","DOI":"10.4319\/lo.1999.44.3_part_2.0864","article-title":"Synergism and antagonism among multiple stressors","volume":"44","author":"Folt","year":"1999","journal-title":"Limnol. Oceanogr."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0135","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1111\/1365-2664.12111","article-title":"Review: an overview of the environmental risks posed by neonicotinoid insecticides","volume":"50","author":"Goulson","year":"2013","journal-title":"J. Appl. Ecol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0140","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/nature13531","article-title":"Declines in insectivorous birds are associated with high neonicotinoid concentrations","volume":"511","author":"Hallmann","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0185809","article-title":"More than 75 percent decline over 27 years in total flying insect biomass in protected areas","volume":"12","author":"Hallmann","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0150","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10452-012-9388-x","article-title":"Incorporating invertebrate predators into theory regarding the timing of invertebrate drift","volume":"46","author":"Hammock","year":"2012","journal-title":"Aquat. Ecol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0155","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s10646-011-0778-y","article-title":"Differences in ecological impacts of systemic insecticides with different physicochemical properties on biocenosis of experimental paddy fields","volume":"21","author":"Hayasaka","year":"2012","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0160","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ecoenv.2012.04.004","article-title":"Cumulative ecological impacts of two successive annual treatments of imidacloprid and fipronil on aquatic communities of paddy mesocosms","volume":"80","author":"Hayasaka","year":"2012","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0165","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/20014091111695","article-title":"A review of the effects of multiple stressors on aquatic organisms and analysis of uncertainty factors for use in risk assessment","volume":"31","author":"Heugens","year":"2001","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0170","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1021\/acs.est.7b06388","article-title":"Environmental risks and challenges associated with neonicotinoid insecticides","volume":"52","author":"Hladik","year":"2018","journal-title":"Environmental Science & Technology"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0175","doi-asserted-by":"crossref","first-page":"3746","DOI":"10.1016\/j.scitotenv.2009.10.067","article-title":"Interactions between effects of environmental chemicals and natural stressors: a review","volume":"408","author":"Holmstrup","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0180","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/etc.2043","article-title":"Interactions between chemical and climate stressors: a role for mechanistic toxicology in assessing climate change risks","volume":"32","author":"Hooper","year":"2013","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0185","doi-asserted-by":"crossref","DOI":"10.3390\/w11102142","article-title":"Food shortage amplifies negative sublethal impacts of low-level exposure to the neonicotinoid insecticide imidacloprid on stream mayfly nymphs","volume":"11","author":"Hunn","year":"2019","journal-title":"Water"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0190","series-title":"Summary for Policymakers","author":"IPCC","year":"2014"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0195","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0068107","article-title":"Fitness effects of chlorpyrifos in the damselfly Enallagma cyathigerum strongly depend upon temperature and food level and can bridge metamorphosis","volume":"8","author":"Janssens","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0200","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.aquatox.2014.01.002","article-title":"Extreme temperatures in the adult stage shape delayed effects of larval pesticide stress: a comparison between latitudes","volume":"148","author":"Janssens","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0205","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.envpol.2017.06.082","article-title":"Testing the time-scale dependence of delayed interactions: a heat wave during the egg stage shapes how a pesticide interacts with a successive heat wave in the larval stage","volume":"230","author":"Janssens","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0210","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1021\/jf101303g","article-title":"Overview of the status and global strategy for neonicotinoids","volume":"59","author":"Jeschke","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0215","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cois.2016.07.001","article-title":"Can we predict the effects of multiple stressors on insects in a changing climate?","volume":"17","author":"Kaunisto","year":"2016","journal-title":"Current Opinion in Insect Science"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0220","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/ele.12193","article-title":"Beyond realism in climate change experiments: gradient approaches identify thresholds and tipping points","volume":"17","author":"Kreyling","year":"2014","journal-title":"Ecol. Lett."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0225","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1111\/faf.12305","article-title":"Multiple-stressor effects on freshwater fish: importance of taxonomy and life stage","volume":"19","author":"Lange","year":"2018","journal-title":"Fish Fish."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0230","doi-asserted-by":"crossref","first-page":"3763","DOI":"10.1016\/j.scitotenv.2010.01.043","article-title":"Interactions between toxic chemicals and natural environmental factors \u2014 a meta-analysis and case studies","volume":"408","author":"Laskowski","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0235","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1002\/etc.198","article-title":"Toxicity of three binary mixtures to Daphnia magna: comparing chemical modes of action and deviations from conceptual models","volume":"29","author":"Loureiro","year":"2010","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0240","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1002\/etc.4556","article-title":"Chronic toxicities of neonicotinoids to nymphs of the common New Zealand mayfly Deleatidium spp","volume":"38","author":"Macaulay","year":"2019","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0245","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/00288330.2019.1614961","article-title":"Water temperature interacts with the insecticide imidacloprid to alter acute lethal and sublethal toxicity to mayfly larvae","volume":"54","author":"Macaulay","year":"2020","journal-title":"N. Z. J. Mar. Freshw. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0250","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ecolind.2015.08.024","article-title":"Multiple-stressor effects on stream invertebrates: DNA barcoding reveals contrasting responses of cryptic mayfly species","volume":"61","author":"Macher","year":"2016","journal-title":"Ecol. Indic."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0255","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.ecoenv.2018.03.003","article-title":"Can chronic exposure to imidacloprid, clothianidin, and thiamethoxam mixtures exert greater than additive toxicity in Chironomus dilutus?","volume":"156","author":"Maloney","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0260","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.2307\/1941612","article-title":"Interpopulation variation in mayfly antipredator tactics: differential effects of contrasting predatory fish","volume":"75","author":"McIntosh","year":"1994","journal-title":"Ecology"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0265","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1126\/science.1098704","article-title":"More intense, more frequent, and longer lasting heat waves in the 21st century","volume":"305","author":"Meehl","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0270","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0169-5347(01)02124-3","article-title":"Compensation for a bad start: grow now, pay later?","volume":"16","author":"Metcalfe","year":"2001","journal-title":"Trends Ecol. Evol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0275","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.envint.2014.10.024","article-title":"Neonicotinoid contamination of global surface waters and associated risk to aquatic invertebrates: a review","volume":"74","author":"Morrissey","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0280","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1111\/j.1469-185X.2007.00027.x","article-title":"Effect size, confidence interval and statistical significance: a practical guide for biologists","volume":"82","author":"Nakagawa","year":"2007","journal-title":"Biol. Rev."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0285","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.chemosphere.2018.06.102","article-title":"Acute and (sub)chronic toxicity of the neonicotinoid imidacloprid on Chironomus riparius","volume":"209","author":"Naveen","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0290","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1093\/czoolo\/61.4.614","article-title":"Heating up the environmental context of chemical pollution: ecotoxicology in a changing global climate","volume":"61","author":"Noyes","year":"2015","journal-title":"Current Zoology"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0295","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.envint.2009.02.006","article-title":"The toxicology of climate change: environmental contaminants in a warming world","volume":"35","author":"Noyes","year":"2009","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0300","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0062472","article-title":"The insecticide imidacloprid causes mortality of the freshwater amphipod Gammarus pulex by interfering with feeding behavior","volume":"8","author":"Nyman","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0305","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1126\/science.1257259","article-title":"Extinctions of aculeate pollinators in Britain and the role of large-scale agricultural changes","volume":"346","author":"Ollerton","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0310","article-title":"Towards a unified study of multiple stressors: divisions and common goals across research disciplines","volume":"287","author":"Orr","year":"2020","journal-title":"Proc. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0315","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s004420050410","article-title":"Fitness and community consequences of avoiding multiple predators","volume":"113","author":"Peckarsky","year":"1998","journal-title":"Oecologia"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0320","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.aquatox.2009.04.008","article-title":"Fear and loathing in the benthos: responses of aquatic insect larvae to the pesticide imidacloprid in the presence of chemical signals of predation risk","volume":"93","author":"Pestana","year":"2009","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0325","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1002\/ece3.1465","article-title":"Reconceptualizing synergism and antagonism among multiple stressors","volume":"5","author":"Piggott","year":"2015","journal-title":"Ecology and Evolution"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0330","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s001140100216","article-title":"Climate change and temperature-dependent biogeography: oxygen limitation of thermal tolerance in animals","volume":"88","author":"P\u00f6rtner","year":"2001","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0335","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.tree.2010.01.007","article-title":"Global pollinator declines: trends, impacts and drivers","volume":"25","author":"Potts","year":"2010","journal-title":"Trends Ecol. Evol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0340","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1080\/00288330.1990.9516432","article-title":"Characterisation and classification of benthic invertebrate communities in 88 New Zealand rivers in relation to environmental factors","volume":"24","author":"Quinn","year":"1990","journal-title":"N. Z. J. Mar. Freshw. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0345","series-title":"Experimental Design and Data Analysis for Biologists","author":"Quinn","year":"2002"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0350","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1080\/00288330.1994.9516629","article-title":"Upper thermal tolerances of twelve New Zealand stream invertebrate species","volume":"28","author":"Quinn","year":"1994","journal-title":"N. Z. J. Mar. Freshw. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb2005","series-title":"R: A language and environment for statistical computing","year":"2019"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0355","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1002\/etc.4088","article-title":"Acute toxicity of 6 neonicotinoid insecticides to freshwater invertebrates","volume":"37","author":"Raby","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0360","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.1002\/etc.4234","article-title":"Chronic toxicity of 6 neonicotinoid insecticides to Chironomus dilutus and Neocloeon triangulifer","volume":"37","author":"Raby","year":"2018","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0365","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1002\/etc.2201","article-title":"The neonicotinoid imidacloprid shows high chronic toxicity to mayfly nymphs","volume":"32","author":"Roessink","year":"2013","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0370","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1071\/MF04120","article-title":"Effects of patchy shade on stream water temperature: how quickly do small streams heat and cool?","volume":"55","author":"Rutherford","year":"2004","journal-title":"Mar. Freshw. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0375","series-title":"Toxicity and Hazard of Agrochemicals. CC BY 3.0 License","article-title":"Environmental risk assessment of agrochemicals \u2014 a critical appraisal of current approaches","author":"S\u00e1nchez-Bayo","year":"2015"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0380","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.3390\/ijerph17051629","article-title":"Time-cumulative toxicity of neonicotinoids: experimental evidence and implications for environmental risk assessments","volume":"17","author":"S\u00e1nchez-Bayo","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0385","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.biocon.2019.01.020","article-title":"Worldwide decline of the entomofauna: a review of its drivers","volume":"232","author":"S\u00e1nchez-Bayo","year":"2019","journal-title":"Biol. Conserv."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0390","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fenvs.2016.00071","article-title":"Contamination of the aquatic environment with neonicotinoids and its implication for ecosystems","volume":"4","author":"S\u00e1nchez-Bayo","year":"2016","journal-title":"Frontiers in Environmental Science"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0395","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.ecoenv.2016.12.009","article-title":"Assessment of thiamethoxam toxicity to Chironomus riparius","volume":"137","author":"Saraiva","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0400","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1111\/gcb.14073","article-title":"Advancing understanding and prediction in multiple stressor research through a mechanistic basis for null models","volume":"24","author":"Sch\u00e4fer","year":"2018","journal-title":"Glob. Chang. Biol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0405","series-title":"Ecological Impacts of Toxic Chemicals","first-page":"111","article-title":"Impacts of pesticides on freshwater ecosystems","author":"Sch\u00e4fer","year":"2011"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0410","doi-asserted-by":"crossref","first-page":"6167","DOI":"10.1021\/es2013006","article-title":"Occurrence and toxicity of 331 organic pollutants in large rivers of North Germany over a decade (1994 to 2004)","volume":"45","author":"Sch\u00e4fer","year":"2011","journal-title":"Environmental Science & Technology"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0415","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/00288330.1991.9516457","article-title":"Life history and production of Deleatidium (Ephemeroptera: Leptophlebiidae) in an unstable New Zealand river","volume":"25","author":"Scrimgeour","year":"1991","journal-title":"N. Z. J. Mar. Freshw. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0420","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.aquatox.2011.06.016","article-title":"Moving beyond a descriptive aquatic toxicology: the value of biological process and trait information","volume":"105","author":"Segner","year":"2011","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0425","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1080\/10807039.2014.964071","article-title":"Ecotoxicity of imidacloprid to aquatic organisms: derivation of water quality standards for peak and long-term exposure","volume":"21","author":"Smit","year":"2015","journal-title":"Human and Ecological Risk Assessment: An International Journal"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0430","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3354\/cr00764","article-title":"Interactive effects of metal pollution and temperature on metabolism in aquatic ectotherms: implications of global climate change","volume":"37","author":"Sokolova","year":"2008","journal-title":"Clim. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0435","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.1002\/etc.5620161209","article-title":"Comparative toxicity of four insecticides, including imidacloprid and tebufenozide, to four aquatic arthropods","volume":"16","author":"Song","year":"1997","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0440","doi-asserted-by":"crossref","first-page":"5750","DOI":"10.1073\/pnas.1500232112","article-title":"Agricultural insecticides threaten surface waters at the global scale","volume":"112","author":"Stehle","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0445","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1126\/science.200.4340.444","article-title":"Size variation and the distribution of hemimetabolous aquatic insects: two thermal equilibrium hypotheses","volume":"200","author":"Sweeney","year":"1978","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0450","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1139\/f00-255","article-title":"Sampling stream invertebrates using electroshocking techniques: implications for basic and applied research","volume":"58","author":"Taylor","year":"2001","journal-title":"Can. J. Fish. Aquat. Sci."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0455","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/ele.12095","article-title":"Means and extremes: building variability into community-level climate change experiments","volume":"16","author":"Thompson","year":"2013","journal-title":"Ecol. Lett."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0460","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1126\/science.1057544","article-title":"Forecasting agriculturally driven global environmental change","volume":"292","author":"Tilman","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0465","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.134811","article-title":"The effect of warming on pesticide toxicity is reversed between developmental stages in the mosquito Culex pipiens","volume":"717","author":"Tran","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0470","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/etc.3152","article-title":"Acute and chronic toxicity of neonicotinoids to nymphs of a mayfly species and some notes on seasonal differences","volume":"35","author":"Van den Brink","year":"2016","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0475","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11356-014-3220-1","article-title":"Worldwide integrated assessment on systemic pesticides","volume":"22","author":"Van Lexmond","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0480","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1086\/283591","article-title":"Geographic analysis of thermal equilibria - a conceptual-model for evaluating the effect of natural and modified thermal regimes on aquatic insect communities","volume":"115","author":"Vannote","year":"1980","journal-title":"Am. Nat."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0485","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1897\/IEAM_2007-056.1","article-title":"Comparison of a score-based approach with risk-based ranking of in-use agricultural pesticides in Canada to aquatic receptors","volume":"4","author":"Whiteside","year":"2008","journal-title":"Integr. Environ. Assess. Manag."},{"key":"10.1016\/j.scitotenv.2020.141941_bb0490","doi-asserted-by":"crossref","first-page":"4971","DOI":"10.1021\/acs.est.6b00315","article-title":"Trait characteristics determine pyrethroid sensitivity in nonstandard test species of freshwater macroinvertebrates: a reality check","volume":"50","author":"Wiberg-Larsen","year":"2016","journal-title":"Environmental Science & Technology"},{"key":"10.1016\/j.scitotenv.2020.141941_bb0495","doi-asserted-by":"crossref","first-page":"17285","DOI":"10.1007\/s11356-017-9240-x","article-title":"The environmental risks of neonicotinoid pesticides: a review of the evidence post 2013","volume":"24","author":"Wood","year":"2017","journal-title":"Environ. Sci. Pollut. Res. Int."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896972035470X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896972035470X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:01:57Z","timestamp":1790258517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004896972035470X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":100,"alternative-id":["S004896972035470X"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2020.141941","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Time-cumulative effects of neonicotinoid exposure, heatwaves and food limitation on stream mayfly nymphs: A multiple-stressor experiment","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2020.141941","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"141941"}}