{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:38:24Z","timestamp":1788482304366,"version":"build-2803163510"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.scitotenv.2021.148259","type":"journal-article","created":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T08:17:01Z","timestamp":1623917821000},"page":"148259","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"special_numbering":"C","title":["Co-occurrence of antimicrobial and metal resistance genes in pig feces and agricultural fields fertilized with slurry"],"prefix":"10.1016","volume":"792","author":[{"given":"Shifu","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Herrero-Fresno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Dalsgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2021.148259_bb0010","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1089\/fpd.2014.1851","article-title":"Nasal carriage of mecA-positive methicillin-resistant Staphylococcus aureus in pigs exhibits dose-response to zinc supplementation","volume":"12","author":"Amachawadi","year":"2015","journal-title":"Foodborne Pathog. Dis."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0015","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.tim.2006.02.006","article-title":"Co-selection of antibiotic and metal resistance","volume":"14","author":"Baker-Austin","year":"2006","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0020","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1128\/CMR.00059-12","article-title":"Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?","volume":"26","author":"Beceiro","year":"2013","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0025","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.ijmm.2013.06.004","article-title":"The broader context of antibiotic resistance: zinc feed supplementation of piglets increases the proportion of multi-resistant Escherichia coli in vivo","volume":"303","author":"Bednorz","year":"2013","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0030","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/nrmicro3439","article-title":"Tackling antibiotic resistance: the environmental framework","volume":"13","author":"Berendonk","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0035","doi-asserted-by":"crossref","first-page":"4544","DOI":"10.1039\/C4CC10174J","article-title":"Advances in the molecular understanding of biological zinc transport","volume":"51","author":"Blindauer","year":"2015","journal-title":"Chem. Commun. (Camb.)"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0040","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.tim.2007.05.004","article-title":"Integrons: mobilizable platforms that promote genetic diversity in bacteria","volume":"15","author":"Boucher","year":"2007","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0045","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.scitotenv.2005.10.007","article-title":"Occurrence of antibiotics in hospital, residential, and dairy effluent, municipal wastewater, and the Rio Grande in New Mexico","volume":"366","author":"Brown","year":"2006","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0050","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1017\/S0007087498003318","article-title":"Penicillin and the new Elizabethans","volume":"31","author":"Bud","year":"1998","journal-title":"Br. J. Hist. Sci."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0055","doi-asserted-by":"crossref","first-page":"3895","DOI":"10.1128\/AAC.02412-14","article-title":"In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing","volume":"58","author":"Carattoli","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0060","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s12866-019-1537-0","article-title":"Molecular characteristics of oxazolidinone resistance in enterococci from a multicenter study in China","volume":"19","author":"Chen","year":"2019","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0065","unstructured":"Chen, N., 2015. Maps reveal extent of China's antibiotics pollution [Online]. Available: http:\/\/english.cas.cn\/newsroom\/news\/201507\/t20150715_150362.shtml [Accessed]."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0070","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.envint.2018.12.055","article-title":"A comparative metagenomic and spectroscopic analysis of soils from an international point of entry between the US and Mexico","volume":"123","author":"Cota-Ruiz","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0075","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1128\/MMBR.00016-10","article-title":"Origins and evolution of antibiotic resistance","volume":"74","author":"Davies","year":"2010","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0080","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1126\/science.1120800","article-title":"Sampling the antibiotic resistome","volume":"311","author":"D'costa","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105117","article-title":"Heavy metal pollution and co-selection for antibiotic resistance: a microbial palaeontology approach","volume":"132","author":"Dickinson","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0090","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/S0140-6736(00)04519-0","article-title":"Persistence of sulphonamide resistance in Escherichia coli in the UK despite national prescribing restriction","volume":"357","author":"Enne","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0095","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.vetmic.2017.07.030","article-title":"Distribution of optrA and cfr in florfenicol-resistant Staphylococcus sciuri of pig origin","volume":"210","author":"Fan","year":"2017","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0100","doi-asserted-by":"crossref","first-page":"3150","DOI":"10.1093\/bioinformatics\/bts565","article-title":"CD-HIT: accelerated for clustering the next-generation sequencing data","volume":"28","author":"Fu","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0105","doi-asserted-by":"crossref","first-page":"D261","DOI":"10.1093\/nar\/gku1223","article-title":"Expanded microbial genome coverage and improved protein family annotation in the COG database","volume":"43","author":"Galperin","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0110","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.scitotenv.2018.02.122","article-title":"Diverse and abundant antibiotic resistance genes from mariculture sites of China\u2019s coastline","volume":"630","author":"Gao","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0115","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.scitotenv.2017.11.221","article-title":"Mobile genetic elements and antibiotic resistance in mine soil amended with organic wastes","volume":"621","author":"Garbisu","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0120","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0022-2836(02)01271-8","article-title":"Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with d-captopril","volume":"325","author":"Garcia-Saez","year":"2003","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0125","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1080\/03601234.2016.1142743","article-title":"Pollution characteristics of 23 veterinary antibiotics in livestock manure and manure-amended soils in Jiangsu province, China","volume":"51","author":"Guo","year":"2016","journal-title":"J. Environ. Sci. Health B"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1004957","article-title":"MEGAN community edition - interactive exploration and analysis of large-scale microbiome sequencing data","volume":"12","author":"Huson","year":"2016","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0135","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.bbagen.2013.10.010","article-title":"The Salmonella enterica ZinT structure, zinc affinity and interaction with the high-affinity uptake protein ZnuA provide insight into the management of periplasmic zinc","volume":"1840","author":"Ilari","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0140","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.biortech.2017.10.073","article-title":"Fate of antibiotic resistance genes and metal resistance genes during thermophilic aerobic digestion of sewage sludge","volume":"249","author":"Jang","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0145","first-page":"420","article-title":"Widespread dissemination of class 1 integron components in soils and related ecosystems as revealed by cultivation-independent analysis","volume":"4","author":"Jechalke","year":"2013","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0150","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jhazmat.2012.07.040","article-title":"Antibiotic resistance gene abundances associated with antibiotics and heavy metals in animal manures and agricultural soils adjacent to feedlots in Shanghai; China","volume":"235-236","author":"Ji","year":"2012","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0155","doi-asserted-by":"crossref","first-page":"D566","DOI":"10.1093\/nar\/gkw1004","article-title":"CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database","volume":"45","author":"Jia","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027300","article-title":"Antibiotic resistance gene abundances correlate with metal and geochemical conditions in archived Scottish soils","volume":"6","author":"Knapp","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0165","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1007\/s11356-016-7997-y","article-title":"Relationship between antibiotic resistance genes and metals in residential soil samples from Western Australia","volume":"24","author":"Knapp","year":"2017","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0139437","article-title":"Assessment of bacterial community assembly patterns and processes in pig manure slurry","volume":"10","author":"Kumari","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0175","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2015.00536","article-title":"Spread of tetracycline resistance genes at a conventional dairy farm","volume":"6","author":"Kyselkova","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0180","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1128\/JB.187.3.1124-1134.2005","article-title":"Genome-wide transcriptional response of chemostat-cultured Escherichia coli to zinc","volume":"187","author":"Lee","year":"2005","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0185","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ymeth.2016.02.020","article-title":"MEGAHIT v1.0: a fast and scalable metagenome assembler driven by advanced methodologies and community practices","volume":"102","author":"Li","year":"2016","journal-title":"Methods"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0190","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1093\/jac\/dkw040","article-title":"Co-location of the oxazolidinone resistance genes optrA and cfr on a multiresistance plasmid from Staphylococcus sciuri","volume":"71","author":"Li","year":"2016","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0195","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.scitotenv.2017.01.124","article-title":"Sources and fate of antimicrobials in integrated fish-pig and non-integrated tilapia farms","volume":"595","author":"Li","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0200","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/ismej.2016.155","article-title":"Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection","volume":"11","author":"Li","year":"2017","journal-title":"ISME J."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0205","first-page":"809","article-title":"Determination of 9 heavy metal elements in sediment by ICP-MS using microwave digestion for sample preparation","volume":"32","author":"Liang","year":"2012","journal-title":"Guang Pu Xue Yu Guang Pu Fen Xi"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0210","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1039\/b802311e","article-title":"Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols","volume":"6","author":"Lienard","year":"2008","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0215","doi-asserted-by":"crossref","first-page":"4046","DOI":"10.1021\/es400238g","article-title":"Tetracycline resistance and class 1 integron genes associated with indoor and outdoor aerosols","volume":"47","author":"Ling","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0220","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1177\/2042098614554919","article-title":"Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem","volume":"5","author":"Llor","year":"2014","journal-title":"Ther. Adv. Drug. Saf."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0225","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1186\/s12859-014-0366-2","article-title":"Rapid evaluation and quality control of next generation sequencing data with FaQCs","volume":"15","author":"Lo","year":"2014","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0230","doi-asserted-by":"crossref","first-page":"D490","DOI":"10.1093\/nar\/gkt1178","article-title":"The carbohydrate-active enzymes database (CAZy) in 2013","volume":"42","author":"Lombard","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0235","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.scitotenv.2016.01.132","article-title":"Fate and transport of tylosin-resistant bacteria and macrolide resistance genes in artificially drained agricultural fields receiving swine manure","volume":"550","author":"Luby","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0240","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1021\/acs.est.6b05100","article-title":"Antibiotic resistance genes and correlations with microbial community and metal resistance genes in full-scale biogas reactors as revealed by metagenomic analysis","volume":"51","author":"Luo","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0245","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1126\/science.1159483","article-title":"Antibiotics and antibiotic resistance genes in natural environments","volume":"321","author":"Martinez","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0250","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00587-17","article-title":"Zinc acquisition mechanisms differ between environmental and virulent Francisella species","volume":"200","author":"Moreau","year":"2018","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0255","doi-asserted-by":"crossref","first-page":"W182","DOI":"10.1093\/nar\/gkm321","article-title":"KAAS: an automatic genome annotation and pathway reconstruction server","volume":"35","author":"Moriya","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0260","first-page":"3192","article-title":"Determination of heavy metal elements in diatomite filter aid by inductively coupled plasma mass spectrometry","volume":"35","author":"Nie","year":"2015","journal-title":"Guang Pu Xue Yu Guang Pu Fen Xi"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0265","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.molmed.2012.03.003","article-title":"Carbapenem resistance in Enterobacteriaceae: here is the storm!","volume":"18","author":"Nordmann","year":"2012","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0270","doi-asserted-by":"crossref","first-page":"584","DOI":"10.5713\/ajas.14.0651","article-title":"Characterization of the fecal microbial communities of duroc pigs using 16S rRNA gene pyrosequencing","volume":"28","author":"Pajarillo","year":"2015","journal-title":"Asian Australas. J. Anim. Sci."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0275","doi-asserted-by":"crossref","first-page":"D737","DOI":"10.1093\/nar\/gkt1252","article-title":"BacMet: antibacterial biocide and metal resistance genes database","volume":"42","author":"Pal","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0280","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1186\/s12864-015-2153-5","article-title":"Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential","volume":"16","author":"Pal","year":"2015","journal-title":"BMC Genomics"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0285","doi-asserted-by":"crossref","unstructured":"Pan, L.B., Ma, J., Wang, X.L., Hou, H., 2016. Heavy metals in soils from a typical county in Shanxi Province, China: levels, sources and spatial distribution. Chemosphere vol. 148, 248\u2013254.","DOI":"10.1016\/j.chemosphere.2015.12.049"},{"issue":"1","key":"10.1016\/j.scitotenv.2021.148259_bb0005","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.1038\/s41467-018-06393-w","article-title":"Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements","volume":"9","author":"Parnanen","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0290","doi-asserted-by":"crossref","first-page":"3753","DOI":"10.1128\/AEM.03080-09","article-title":"Identification of diverse antimicrobial resistance determinants carried on bacterial, plasmid, or viral metagenomes from an activated sludge microbial assemblage","volume":"76","author":"Parsley","year":"2010","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0295","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00088-17","article-title":"Mobile genetic elements associated with antimicrobial resistance","volume":"31","author":"Partridge","year":"2018","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0300","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.3389\/fmicb.2018.01669","article-title":"Comparative transcriptome analysis of Pseudomonas putida KT2440 revealed its response mechanisms to elevated levels of zinc stress","volume":"9","author":"Peng","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0305","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.jgar.2020.06.004","article-title":"Influence of zinc on CTX-M-1 beta-lactamase expression in Escherichia coli","volume":"22","author":"Peng","year":"2020","journal-title":"J. Glob. Antimicrob. Resist."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0310","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1128\/JB.01310-09","article-title":"The Zur-regulated ZinT protein is an auxiliary component of the high-affinity ZnuABC zinc transporter that facilitates metal recruitment during severe zinc shortage","volume":"192","author":"Petrarca","year":"2010","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0315","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0046505","article-title":"When does overuse of antibiotics become a tragedy of the commons?","volume":"7","author":"Porco","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0320","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.envpol.2014.02.031","article-title":"Bacterial metal resistance genes and metal bioavailability in contaminated sediments","volume":"189","author":"Roosa","year":"2014","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0325","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.chemosphere.2006.03.026","article-title":"A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment","volume":"65","author":"Sarmah","year":"2006","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0330","doi-asserted-by":"crossref","first-page":"399","DOI":"10.3389\/fmicb.2012.00399","article-title":"Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture","volume":"3","author":"Seiler","year":"2012","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0335","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.3390\/w12123313","article-title":"Antimicrobials and antibiotic-resistant bacteria: a risk to the environment and to public health","volume":"12","author":"Serweci\u0144ska","year":"2020","journal-title":"Water"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0340","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/zph.12150","article-title":"Zinc oxide therapy increases prevalence and persistence of methicillin-resistant Staphylococcus aureus in pigs: a randomized controlled trial","volume":"62","author":"Slifierz","year":"2015","journal-title":"Zoonoses Public Health"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0345","doi-asserted-by":"crossref","first-page":"3040","DOI":"10.1021\/acs.est.6b05342","article-title":"Comparison of metals and tetracycline as selective agents for development of tetracycline resistant bacterial communities in agricultural soil","volume":"51","author":"Song","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0350","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1111\/1574-6941.12233","article-title":"The impact of high dietary zinc oxide on the development of the intestinal microbiota in weaned piglets","volume":"87","author":"Starke","year":"2014","journal-title":"FEMS Microbiol. Ecol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0355","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.envpol.2018.11.003","article-title":"Fate of microbial pollutants and evolution of antibiotic resistance in three types of soil amended with swine slurry","volume":"245","author":"Sui","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0360","doi-asserted-by":"crossref","first-page":"990","DOI":"10.3389\/fpls.2016.00990","article-title":"Response of soil properties and microbial communities to agriculture: implications for primary productivity and soil health indicators","volume":"7","author":"Trivedi","year":"2016","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0365","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s13099-015-0071-3","article-title":"High dietary zinc supplementation increases the occurrence of tetracycline and sulfonamide resistance genes in the intestine of weaned pigs","volume":"7","author":"Vahjen","year":"2015","journal-title":"Gut. Pathog."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0370","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.1073\/pnas.1503141112","article-title":"Global trends in antimicrobial use in food animals","volume":"112","author":"Van Boeckel","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0375","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.envpol.2018.02.073","article-title":"Antibiotic and heavy metal resistance in enterococci from coastal marine sediment","volume":"237","author":"Vignaroli","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0380","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1039\/c3mt20217h","article-title":"The BaeSR regulon is involved in defense against zinc toxicity in E. coli","volume":"5","author":"Wang","year":"2013","journal-title":"Metallomics"},{"key":"10.1016\/j.scitotenv.2021.148259_bb0385","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1093\/jac\/dkv116","article-title":"A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin","volume":"70","author":"Wang","year":"2015","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0390","doi-asserted-by":"crossref","first-page":"6933","DOI":"10.1021\/es1007802","article-title":"Abundance and diversity of tetracycline resistance genes in soils adjacent to representative swine feedlots in China","volume":"44","author":"Wu","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0395","doi-asserted-by":"crossref","first-page":"13956","DOI":"10.1007\/s11356-018-1598-x","article-title":"Fate of antibiotic and metal resistance genes during two-phase anaerobic digestion of residue sludge revealed by metagenomic approach","volume":"25","author":"Wu","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0400","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.apsoil.2018.04.001","article-title":"Soil bacterial community composition and diversity in relation to edaphic properties and plant traits in grasslands of southern China","volume":"128","author":"Yang","year":"2018","journal-title":"Appl. Soil Ecol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0405","article-title":"Zinc and copper in animal feed - development of resistance and co-resistance to antimicrobial agents in bacteria of animal origin","volume":"25","author":"Yazdankhah","year":"2014","journal-title":"Microb. Ecol. Health Dis."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0410","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.fm.2016.12.009","article-title":"Antimicrobial resistance and its association with tolerance to heavy metals in agriculture production","volume":"64","author":"Yu","year":"2017","journal-title":"Food Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0415","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ecoenv.2018.05.049","article-title":"Antibiotic resistance genes and intI1 prevalence in a swine wastewater treatment plant and correlation with metal resistance, bacterial community and wastewater parameters","volume":"161","author":"Yuan","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0420","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.scitotenv.2018.11.372","article-title":"Evidence for co-selection of antibiotic resistance genes and mobile genetic elements in metal polluted urban soils","volume":"656","author":"Zhao","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0425","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1128\/aem.62.2.316-322.1996","article-title":"DNA recovery from soils of diverse composition","volume":"62","author":"Zhou","year":"1996","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0430","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkq275","article-title":"Ab initio gene identification in metagenomic sequences","volume":"38","author":"Zhu","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0435","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1073\/pnas.1222743110","article-title":"Diverse and abundant antibiotic resistance genes in Chinese swine farms","volume":"110","author":"Zhu","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2021.148259_bb0440","doi-asserted-by":"crossref","first-page":"E84","DOI":"10.2527\/jas.2009-2331","article-title":"Fate and transport of zoonotic, bacterial, viral, and parasitic pathogens during swine manure treatment, storage, and land application","volume":"88","author":"Ziemer","year":"2010","journal-title":"J. Anim. Sci."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721033301?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721033301?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T13:47:36Z","timestamp":1785937656000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969721033301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":88,"alternative-id":["S0048969721033301"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.148259","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Co-occurrence of antimicrobial and metal resistance genes in pig feces and agricultural fields fertilized with slurry","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.148259","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"148259"}}