{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:28:24Z","timestamp":1791390504157,"version":"4.3.3"},"reference-count":79,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T00:00:00Z","timestamp":1628467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["267820"],"award-info":[{"award-number":["267820"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016931","name":"Havforskningsinstituttet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016931","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.scitotenv.2021.149460","type":"journal-article","created":{"date-parts":[[2021,8,5]],"date-time":"2021-08-05T07:09:09Z","timestamp":1628147349000},"page":"149460","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Cardiac dysfunction affects eye development and vision by reducing supply of lipids in fish"],"prefix":"10.1016","volume":"800","author":[{"given":"Elin","family":"S\u00f8rhus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonnich","family":"Meier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carey E.","family":"Donald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Furmanek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf B.","family":"Edvardsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai K.","family":"Lie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2021.149460_bb0005","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1194\/jlr.R005025","article-title":"Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein","volume":"51","author":"Agbaga","year":"2010","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.124608","article-title":"Understanding the cardiac toxicity of the anthropogenic pollutant phenanthrene on the freshwater indicator species, the brown trout (Salmo trutta): from whole heart to cardiomyocytes","volume":"239","author":"Ainerua","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0015","doi-asserted-by":"crossref","first-page":"6290","DOI":"10.1021\/es049765n","article-title":"Dietary retinoic acid induces hindlimb and eye deformities in Xenopus laevis","volume":"38","author":"Alsop","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0020","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/j.1095-8649.1996.tb00091.x","article-title":"Deficit of didocosahexaenoyl phospholipid in the eyes of larval sea bass fed an essential fatty acid deficient diet","volume":"49","author":"Bell","year":"1996","journal-title":"J. Fish Biol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0025","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/anu.12309","article-title":"Polyaromatic hydrocarbons in aquafeeds, source, effects and potential implications for vitamin status of farmed fish species: a review","volume":"21","author":"Berntssen","year":"2015","journal-title":"Aquac. Nutr."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0030","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.aquatox.2016.03.016","article-title":"Dietary vitamin a supplementation ameliorates the effects of poly-aromatic hydrocarbons in Atlantic salmon (Salmo salar)","volume":"175","author":"Berntssen","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0035","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1126\/science.1242747","article-title":"Crude oil impairs cardiac excitation-contraction coupling in fish","volume":"343","author":"Brette","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0040","doi-asserted-by":"crossref","first-page":"41476","DOI":"10.1038\/srep41476","article-title":"A novel cardiotoxic mechanism for a pervasive global pollutant","volume":"7","author":"Brette","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0045","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1016\/j.bbamem.2017.09.017","article-title":"Polycyclic aromatic hydrocarbons in model bacterial membranes - langmuir monolayer studies","volume":"1859","author":"Broniatowski","year":"2017","journal-title":"Bba-Biomembranes"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0050","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1016\/j.bpj.2009.06.037","article-title":"RGS9 concentration matters in rod phototransduction","volume":"97","author":"Burns","year":"2009","journal-title":"Biophys. J."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0055","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1242\/dev.02815","article-title":"RALDH-independent generation of retinoic acid during vertebrate embryogenesis by CYP1B1","volume":"134","author":"Chambers","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0060","series-title":"Effects of exposure to low concentrations of oil on expression of cytochrome P4501a and routine swimming speed of Atlantic haddock (Melanogrammus aeglefinus) larvae in situ","author":"Cresci","year":"2020"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0065","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.exer.2009.04.012","article-title":"Retinoic acid signaling in mammalian eye development","volume":"89","author":"Cvekl","year":"2009","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0070","unstructured":"Drugbank.com, 2020. Nicardipine. Drugbank, https:\/\/go.drugbank.com\/drugs\/DB00622"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0075","article-title":"Cell Mol","author":"Ehab","year":"2021","journal-title":"Life Sci."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0080","series-title":"Cardiac remodeling in response to embryonic crude oil exposure involves unconventional NKX family members and innate immunity genes","first-page":"222","author":"Gardner","year":"2019"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0085","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.bone.2015.04.014","article-title":"Bone and skeletal muscle: key players in mechanotransduction and potential overlapping mechanisms","volume":"80","author":"Goodman","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0090","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1194\/jlr.P065540","article-title":"Associations of human retinal very long-chain polyunsaturated fatty acids with dietary lipid biomarkers","volume":"57","author":"Gorusupudi","year":"2016","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0095","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/jmor.10222","article-title":"Stages of embryonic development in the Atlantic cod Gadus morhua","volume":"259","author":"Hall","year":"2004","journal-title":"J. Morphol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0100","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2020.591406","article-title":"ReCodLiver0.9: overcoming challenges in genome-scale metabolic reconstruction of a non-model species","volume":"7","author":"Hanna","year":"2020","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0105","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1002\/etc.5620210912","article-title":"Altering cytochrome P4501A activity affects polycyclic aromatic hydrocarbon metabolism and toxicity in rainbow trout (Oncorhynchus mykiss)","volume":"21","author":"Hawkins","year":"2002","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0110","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1002\/etc.5620180318","article-title":"Sensitivity of fish embryos to weathered crude oil: part II. increased mortality of pink salmon (Oncorhynchus gorbuscha) embryos incubating downstream from weathered exxon Valdez crude oil","volume":"18","author":"Heintz","year":"1999","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0115","first-page":"9","article-title":"Functional development of the liver and exocrine pancreas","volume":"40","author":"Hoehne-Reitan","year":"2004","journal-title":"Am. Fish. Soc. Symp."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0120","doi-asserted-by":"crossref","first-page":"9797","DOI":"10.1021\/es502221g","article-title":"Lipophilic contaminants influence cold tolerance of invertebrates through changes in cell membrane fluidity","volume":"48","author":"Holmstrup","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0125","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.aquatox.2016.06.016","article-title":"The influence of heart developmental anatomy on cardiotoxicity-based adverse outcome pathways in fish","volume":"177","author":"Incardona","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0130","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.taap.2003.11.026","article-title":"Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons","volume":"196","author":"Incardona","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0135","doi-asserted-by":"crossref","first-page":"13499","DOI":"10.1038\/srep13499","article-title":"Very low embryonic crude oil exposures cause lasting cardiac defects in salmon and herring","volume":"5","author":"Incardona","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0140","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s11160-007-9070-x","article-title":"Resource allocation in yolk-feeding fish","volume":"18","author":"Kamler","year":"2008","journal-title":"Rev. Fish Biol. Fisher."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0145","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/978-0-387-46954-6_7","article-title":"Cranial neural crest and development of the head skeleton","volume":"589","author":"Knight","year":"2006","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0150","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/0006-2952(83)90532-4","article-title":"Activation of glycogenolysis by the reduction in the extracellular calcium-concentration in verapamil-perfused rat-liver","volume":"32","author":"Koide","year":"1983","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0155","series-title":"Phenanthrene impacts zebrafish cardiomyocyte excitability by inhibiting I-kr and shortening action potential duration","first-page":"153","author":"Kompella","year":"2021"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0160","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.aquaculture.2017.09.039","article-title":"The effect of dietary DHA and taurine on rotifer capture success, growth, survival and vision in the larvae of Atlantic bluefin tuna (Thunnus thynnus)","volume":"482","author":"Koven","year":"2018","journal-title":"Aquaculture"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0165","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2009-10-3-r25","article-title":"Ultrafast and memory-efficient alignment of short DNA sequences to the human genome","volume":"10","author":"Langmead","year":"2009","journal-title":"Genome Biol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0170","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1017\/S0952523812000296","article-title":"Early retinoic acid deprivation in developing zebrafish results in microphthalmia","volume":"29","author":"Le","year":"2012","journal-title":"Vis. Neurosci."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0175","series-title":"Offshore crude oil disrupts retinoid signaling and eye development in larval Atlantic haddock","first-page":"6","author":"Lie","year":"2019"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0180","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.chemphyslip.2014.08.004","article-title":"Polyaromatic hydrocarbons do not disturb liquid-liquid phase coexistence, but increase the fluidity of model membranes","volume":"184","author":"Liland","year":"2014","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0185","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ecoenv.2018.09.087","article-title":"Effects of Deepwater horizon crude oil on ocular development in two estuarine fish species, red drum (Sciaenops ocellatus) and sheepshead minnow (Cyprinodon variegatus)","volume":"166","author":"Magnuson","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0190","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1113\/JP278885","article-title":"Polyaromatic hydrocarbons in pollution: a heart-breaking matter","volume":"598","author":"Marris","year":"2019","journal-title":"J. Physiol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0195","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s00109-009-0449-0","article-title":"Elovl6: a new player in fatty acid metabolism and insulin sensitivity","volume":"87","author":"Matsuzaka","year":"2009","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0200","series-title":"Effects of phenanthrene exposure on cholesterol homeostasis and cardiotoxicity in zebrafish embryos","author":"McGruer","year":"2021"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0205","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.chroma.2005.11.045","article-title":"Validation of a one-step extraction\/methylation method for determination of fatty acids and cholesterol in marine tissues","volume":"1104","author":"Meier","year":"2006","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0210","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.cbpc.2007.01.012","article-title":"Effects of alkylphenols on glycerophospholipids and cholesterol in liver and brain from female Atlantic cod (Gadus morhua)","volume":"145","author":"Meier","year":"2007","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0215","series-title":"Kaplan\u2019s Essentials of Cardiac Anesthesia","first-page":"322","article-title":"Chapter 14 - anesthesia for myocardial revascularization","author":"Mittnacht","year":"2018"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0220","series-title":"Molecular and functional characterization of Elovl4 genes in Sparus aurata and Solea senegalensis pointing to a critical role in very long-chain (>C(24)) fatty acid synthesis during early neural development of fish","first-page":"21","author":"Morais","year":"2020"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0225","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0083-6729(06)75002-6","article-title":"The intersection between the aryl hydrocarbon receptor (AhR)- and retinoic acid-signaling pathways","volume":"75","author":"Murphy","year":"2007","journal-title":"Vitam. Horm."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0230","series-title":"Second messengers","first-page":"8","author":"Newton","year":"2016"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0235","series-title":"Combined effects of elevated temperature and Deepwater horizon oil exposure on the cardiac performance of larval mahi-mahi","first-page":"13","author":"Perrichon","year":"2018"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.145349","article-title":"Differential developmental toxicity of crude oil in early life stages of Atlantic halibut (Hippoglossus hippoglossus)","volume":"770","author":"Perrichon","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0245","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1021\/tx9003165","article-title":"2,3,7,8-tetrachlorodibenzo-p-dioxin upregulates FoxQ1b in zebrafish jaw primordium","volume":"23","author":"Planchart","year":"2010","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb2015","series-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2013"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0250","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/oby.21035","article-title":"Polyunsaturated fatty acid regulation of adipocyte FADS1 and FADS2 expression and function","volume":"23","author":"Ralston","year":"2015","journal-title":"Obesity"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0255","doi-asserted-by":"crossref","first-page":"R425","DOI":"10.1016\/S0960-9822(03)00358-0","article-title":"Calcium-induced calcium release","volume":"13","author":"Roderick","year":"2003","journal-title":"Curr. Biol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0260","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1152\/physrev.2000.80.3.1021","article-title":"Retinoids in embryonal development","volume":"80","author":"Ross","year":"2000","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0265","doi-asserted-by":"crossref","first-page":"668","DOI":"10.3390\/nu10060668","article-title":"The eye, oxidative damage and polyunsaturated fatty acids","volume":"10","author":"Sacc\u00e0","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0270","doi-asserted-by":"crossref","first-page":"93","DOI":"10.2170\/jjphysiol.37.93","article-title":"Inhibition of excitation-contraction coupling by a ca channel blocker nicardipine at low-temperature in frog twitch fibers","volume":"37","author":"Sato","year":"1987","journal-title":"Jpn. J. Physiol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb2010","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0275","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00216-020-03062-0","article-title":"Identification of new, very long-chain polyunsaturated fatty acids in fish by gas chromatography coupled to quadrupole\/time-of-flight mass spectrometry with atmospheric pressure chemical ionization","volume":"413","author":"Serrano","year":"2021","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0280","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ydbio.2012.07.026","article-title":"Muscle contraction controls skeletal morphogenesis through regulation of chondrocyte convergent extension","volume":"370","author":"Shwartz","year":"2012","journal-title":"Dev. Biol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0285","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1002\/rcm.7688","article-title":"Application of gas chromatography\/tandem mass spectrometry to determine a wide range of petrogenic alkylated polycyclic aromatic hydrocarbons in biotic samples","volume":"30","author":"S\u00f8rensen","year":"2016","journal-title":"Rapid Commun Mass Sp"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0180048","article-title":"Oil droplet fouling and differential toxicokinetics of polycyclic aromatic hydrocarbons in embryos of Atlantic haddock and cod","volume":"12","author":"S\u00f8rensen","year":"2017","journal-title":"Plos One"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.133682","article-title":"Establishing a link between composition and toxicity of offshore produced waters using comprehensive analysis techniques - a way forward for discharge monitoring?","volume":"694","author":"S\u00f8rensen","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.149460_bb2005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0124376","article-title":"Unexpected interaction with dispersed crude oil droplets drives severe toxicity in Atlantic haddock embryo","volume":"10","author":"S\u00f8rhus","year":"2015","journal-title":"Plos One"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0300","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.ydbio.2016.02.012","article-title":"Developmental transcriptomics in Atlantic haddock: illuminating pattern formation and organogenesis in non-model vertebrates","volume":"411","author":"S\u00f8rhus","year":"2016","journal-title":"Dev. Biol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0305","doi-asserted-by":"crossref","first-page":"31058","DOI":"10.1038\/srep31058","article-title":"Crude oil exposures reveal roles for intracellular calcium cycling in haddock craniofacial and cardiac development","volume":"6","author":"S\u00f8rhus","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0310","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.20707","article-title":"Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish","volume":"6","author":"S\u00f8rhus","year":"2017","journal-title":"elife"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143896","article-title":"Untangling mechanisms of crude oil toxicity: linking gene expression, morphology and PAHs at two developmental stages in a cold-water fish","volume":"757","author":"S\u00f8rhus","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0320","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nature10342","article-title":"The genome sequence of Atlantic cod reveals a unique immune system","volume":"477","author":"Star","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0325","first-page":"1","article-title":"Motor neurons and the generation of spinal motor neuron diversity","volume":"8","author":"Stifani","year":"2014","journal-title":"Cell Neurosci."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0330","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.cbpc.2004.03.009","article-title":"Fatty acid and lipid class composition in eyes and brain from teleosts and elasmobranchs","volume":"138","author":"Stoknes","year":"2004","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0335","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1194\/jlr.M800170-JLR200","article-title":"High levels of retinal membrane docosahexaenoic acid increase susceptibility to stress-induced degeneration","volume":"50","author":"Tanito","year":"2009","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0340","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1186\/gb-2005-6-3-213","article-title":"The opsins","volume":"6","author":"Terakita","year":"2005","journal-title":"Genome Biol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0345","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.chemosphere.2015.05.041","article-title":"A high throughput passive dosing format for the fish embryo acute toxicity test","volume":"139","author":"Vergauwen","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0350","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/BF02537193","article-title":"Thermal adaptation affects the fatty acid composition of plasma phospholipids in trout","volume":"29","author":"Wallaert","year":"1994","journal-title":"Lipids"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0355","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.chroma.2013.05.056","article-title":"A database of chromatographic properties and mass spectra of fatty acid methyl esters from omega-3 products","volume":"1299","author":"Wasta","year":"2013","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0360","series-title":"Cyp1b1 regulates ocular fissure closure through a retinoic acid-independent pathway","first-page":"58","author":"Williams","year":"2017"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0365","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1124\/mol.108.050435","article-title":"Aryl hydrocarbon receptor-mediated Down-regulation of Sox9b causes jaw malformation in zebrafish embryos","volume":"74","author":"Xiong","year":"2008","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0370","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1096\/fj.00-0061com","article-title":"Regulation of CYP26 (cytochrome P450RAI) mRNA expression and retinoic acid metabolism by retinoids and dietary vitamin a in liver of mice and rats","volume":"14","author":"Yamamoto","year":"2000","journal-title":"FASEB J."},{"key":"10.1016\/j.scitotenv.2021.149460_bb0375","first-page":"11","article-title":"New insights into cholesterol functions: a friend or an Enemy?","author":"Zampelas","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.scitotenv.2021.149460_bb0380","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.aquatox.2013.07.014","article-title":"Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling","volume":"142","author":"Zhang","year":"2013","journal-title":"Aquat. Toxicol."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721045344?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721045344?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T12:56:34Z","timestamp":1758718594000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969721045344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":79,"alternative-id":["S0048969721045344"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.149460","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.05.11.443591","asserted-by":"object"}]},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiac dysfunction affects eye development and vision by reducing supply of lipids in fish","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.149460","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"149460"}}