{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T07:43:52Z","timestamp":1781855032004,"version":"3.54.5"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.scitotenv.2021.151023","type":"journal-article","created":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T17:26:13Z","timestamp":1634577973000},"page":"151023","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"P3","title":["Galleria mellonella for systemic assessment of anti-Candida auris using amphotericin B loaded in nanoemulsion"],"prefix":"10.1016","volume":"807","author":[{"given":"Gabriel Davi","family":"Marena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus Aparecido Dos Santos","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Caminitti","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlus","family":"Chorilli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tais Maria","family":"Bauab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2021.151023_bb0005","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.chemosphere.2018.01.175","article-title":"Galleria mellonella larvae allow the discrimination of toxic and non-toxic chemicals","volume":"198","author":"Allegra","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0455","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ejps.2008.06.002","article-title":"Determination of factors controlling the particle size in nanoemulsions using Artificial Neural Networks","volume":"35","author":"Amani","year":"2008","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0010","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1080\/21505594.2017.1347744","article-title":"Galleria mellonella as a host model to study Candida glabrata virulence and antifungal efficacy","volume":"8","author":"Ames","year":"2017","journal-title":"Virulence"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0015","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0168-1656(98)00139-4","article-title":"Lipophilic compounds in biotechnology - interactions with cells and technological problems","volume":"67","author":"Angelova","year":"1999","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0020","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ejim.2016.06.029","article-title":"Candidemia and invasive candidiasis in adults: a narrative review","volume":"34","author":"Antinori","year":"2016","journal-title":"Eur. J. Intern. Med."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0420","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1080\/1040841X.2020.1803208","article-title":"Nanosystems against candidiasis: a review of studies performed over the last two decades","volume":"46","author":"Araujo","year":"2020","journal-title":"Crit. Rev. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0460","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/1040841X.2020.1843399","article-title":"Exploiting solid lipid nanoparticles and nanostructured lipid carriers for drug delivery against cutaneous fungal infections","volume":"47","author":"Araujo","year":"2021","journal-title":"Crit. Rev. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0025","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1097\/QCO.0000000000000111","article-title":"Echinocandin resistance: an emerging clinical problem?","volume":"27","author":"Arendrup","year":"2014","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/AAC.00476-20","article-title":"Chitosan ameliorates Candida auris virulence in a galleria mellonella infection model","volume":"64","author":"Arias","year":"2020","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0040","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1016\/j.bbadis.2013.03.008","article-title":"Invertebrate models of fungal infection","volume":"1832","author":"Arvanitis","year":"2013","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-41513-6","article-title":"Gene duplication associated with increased fluconazole tolerance in Candida auris cells of advanced generational age","volume":"9","author":"Bhattacharya","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0055","first-page":"1","article-title":"Nanotechnology-based drug delivery systems and herbal medicines: a review","volume":"9","author":"Bonif\u00e1cio","year":"2015","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0060","doi-asserted-by":"crossref","first-page":"5081","DOI":"10.2147\/IJN.S79684","article-title":"Nanostructured lipid system as a strategy to improve the anti-Candida albicans activity of astronium sp","volume":"10","author":"Bonif\u00e1cio","year":"2015","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/mSphere.00189-16","article-title":"Comparative pathogenicity of United Kingdom isolates of the emerging","volume":"1","author":"Borman","year":"2016","journal-title":"mSphere"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0075","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1021\/acs.molpharmaceut.9b01264","article-title":"New Silver(I) coordination compound loaded into polymeric nanoparticles as a strategy to improve in vitro anti- helicobacter pylori activity","volume":"17","author":"Camargo","year":"2020","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0080","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1080\/21505594.2016.1203486","article-title":"Galleria mellonella as a model host for microbiological and toxin research","volume":"7","author":"Champion","year":"2016","journal-title":"Virulence"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.ppat.1006290","article-title":"Candida auris: a rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally","volume":"13","author":"Chowdhary","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0465","series-title":"Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts","author":"Clinical and Laboratory Standards Institute","year":"2017"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0090","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1080\/21505594.2019.1621649","article-title":"Galleria mellonella as a consolidated in vivo model hosts: new developments in antibacterial strategies and novel drug testing","volume":"10","author":"Cutuli","year":"2019","journal-title":"Virulence"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.ppat.1008921","article-title":"Candida auris: epidemiology, biology, antifungal resistance, and virulence","volume":"16","author":"Du","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0475","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1080\/21505594.2021.1928410","article-title":"A biological and genomic comparison of a drug-resistant and a drug-susceptible strain of Candida auris isolated from Beijing, China","volume":"12","author":"Fan","year":"2021","journal-title":"Virulence"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/Spectrum.00013-21","article-title":"Characterization of the differential pathogenicity of Candida auris in a galleria mellonella infection model","volume":"9","author":"Garcia-Bustos","year":"2021","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0115","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1242\/dmm.006619","article-title":"Wild-type Drosophila melanogaster as an alternative model system for investigating the pathogenicity of Candida albicans","volume":"4","author":"Glittenberg","year":"2011","journal-title":"DMM Dis. Model. Mech."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0120","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1007\/s11999-016-5211-7","article-title":"Phosphatidylcholine coatings deliver local antimicrobials and reduce infection in a murine model: a preliminary study","volume":"475","author":"Harris","year":"2017","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0480","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3109\/15563650.2016.1151528","article-title":"Systematic review of clinical adverse events reported after acute intravenous lipid emulsion administration","volume":"54","author":"Hayes","year":"2016","journal-title":"Clin. Toxicol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0125","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jim.2014.03.022","article-title":"Overview of vertebrate animal models of fungal infection","volume":"410","author":"Hohl","year":"2014","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0130","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00029-17","article-title":"Candida auris: a review of the literature","author":"Jeffery-Smith","year":"2018","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0135","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms8030390","article-title":"Galleria mellonella for the evaluation of antifungal efficacy against medically important fungi, a narrative review","volume":"8","author":"Jemel","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0140","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.femsre.2003.09.002","article-title":"Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens","volume":"28","author":"Kavanagh","year":"2004","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0145","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S1773-2247(11)50006-1","article-title":"Lecithin-based nanoemulsions","volume":"21","author":"Klang","year":"2011","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0150","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.micron.2011.07.014","article-title":"Electron microscopy of nanoemulsions: an essential tool for characterisation and stability assessment","volume":"43","author":"Klang","year":"2012","journal-title":"Micron"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0155","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00238-18","article-title":"Understanding echinocandin resistance in the emerging pathogen Candida auris","volume":"62","author":"Kordalewska","year":"2018","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0160","doi-asserted-by":"crossref","first-page":"10369","DOI":"10.1039\/C7CP07626F","article-title":"Nanoemulsions stabilized by non-ionic surfactants: stability and degradation mechanisms","volume":"20","author":"Koroleva","year":"2018","journal-title":"Phys. Chem. Chem. Phys."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0490","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1080\/01932691.2015.1038351","article-title":"Evaluation and optimization of water-in-oil microemulsion using ternary phase diagram and central composite design","volume":"37","author":"Kumar","year":"2016","journal-title":"J. Dispers. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0495","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1080\/21505594.2019.1614382","article-title":"Cryptic species of Aspergillus section Terrei display essential physiological features to cause infection and are similar in their virulence potential in Galleria mellonella","volume":"10","author":"Lackner","year":"2019","journal-title":"Virulence"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0170","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.2174\/1381612826666200317131041","article-title":"Syngonanthus nitens (Bong.) Ruhland derivatives loaded into a lipid nanoemulsion for enhanced antifungal activity against Candida parapsilosis","volume":"26","author":"Lima","year":"2020","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0175","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.jcma.2015.07.008","article-title":"Nanotechnology-based drug delivery treatments and specific targeting therapy for age-related macular degeneration","volume":"78","author":"Lin","year":"2015","journal-title":"J. Chin. Med. Assoc."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0185","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/cid\/ciw691","article-title":"Simultaneous emergence of multidrug-resistant candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses","volume":"64","author":"Lockhart","year":"2017","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0500","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1166\/jpsp.2017.1082","article-title":"Nanoemulsion as targeted drug delivery system for cancer therapeutics","volume":"3","author":"Mahato","year":"2017","journal-title":"J. Pharm. Sci. Pharmacol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0200","article-title":"Incorporation of ursolic acid in liquid crystalline systems improves the antifungal activity against Candida sp","volume":"1\u201311","author":"Marena","year":"2020","journal-title":"J. Pharm. Innov."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0205","first-page":"1","article-title":"Biological properties and analytical methods for micafungin: a critical review","volume":"1","author":"Marena","year":"2020","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0210","first-page":"1","article-title":"A critical review of analytical methods for quantification of amphotericin B in biological samples and pharmaceutical formulations","volume":"1","author":"Marena","year":"2020","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0215","article-title":"Hydroalcoholic extract of Myrcia bella loaded into a microemulsion system: a study of antifungal and mutagenic potential","volume":"1\u201312","author":"Marena","year":"2021","journal-title":"Planta Med."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0225","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1088\/0953-8984\/18\/41\/R01","article-title":"Nanoemulsions: formation, structure, and physical properties","volume":"18","author":"Mason","year":"2006","journal-title":"J. Phys. Condens. Matter"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0230","doi-asserted-by":"crossref","first-page":"21","DOI":"10.2217\/fmb-2019-0095","article-title":"Antifungal activity of 2\u2032-hydroxychalcone loaded in nanoemulsion against paracoccidioides spp","volume":"15","author":"Medina-Alarc\u00f3n","year":"2020","journal-title":"Future Microbiol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0235","doi-asserted-by":"crossref","first-page":"461","DOI":"10.3109\/13693786.2012.737031","article-title":"The non-mammalian host galleria mellonella can be used to study the virulence of the fungal pathogen Candida tropicalis and the efficacy of antifungal drugs during infection by this pathogenic yeast","volume":"51","author":"Mesa-Arango","year":"2013","journal-title":"Med. Mycol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104346","article-title":"Effect of phenotypic switching on biofilm traits in Candida tropicalis","volume":"149","author":"Moralez","year":"2020","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2020.00957","article-title":"In vitro and in vivo effect of exogenous farnesol exposure against Candida auris","volume":"11","author":"Nagy","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0470","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ejpb.2010.05.001","article-title":"Preservation of nanostructured lipid carriers (NLC)","volume":"76","author":"Obeidat","year":"2010","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0265","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cofs.2017.06.003","article-title":"Nanoemulsions: stability and physical properties","volume":"16","author":"Oca-\u00c1valos","year":"2017","journal-title":"Curr. Opin. Food Sci."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0275","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1111\/jphp.12780","article-title":"Echinocandins in antifungal pharmacotherapy","volume":"69","author":"Patil","year":"2017","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0280","first-page":"4","article-title":"Recent advances in the use of Galleria mellonella model to study immune responses against human pathogens","author":"Pereira","year":"2018","journal-title":"J. Fungi"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0285","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1080\/10717544.2016.1228715","article-title":"Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats","volume":"24","author":"Radwan","year":"2017","journal-title":"Drug Deliv."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0295","doi-asserted-by":"crossref","first-page":"7455","DOI":"10.2147\/IJN.S92638","article-title":"Liquid crystal precursor mucoadhesive system as a strategy to improve the prophylactic action of Syngonanthus nitens (bong.) Ruhland against infection by Candida krusei","volume":"10","author":"Ramos","year":"2015","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0305","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.2147\/IJN.S146195","article-title":"Nanotechnology-based drug delivery systems for control of microbial biofilms: a review","volume":"13","author":"Ramos","year":"2018","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0310","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1166\/jbn.2019.2750","article-title":"Intravaginal delivery of Syngonanthus nitens (Bong.) Ruhland fraction based on a nanoemulsion system applied to vulvovaginal candidiasis treatment","volume":"15","author":"Ramos","year":"2019","journal-title":"J. Biomed. Nanotechnol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0315","first-page":"1","article-title":"Nanotechnological strategies for systemic microbial infections treatment: a review","volume":"589","author":"Ramos","year":"2020","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0320","article-title":"Nanotechnology-based lipid systems applied to resistant bacterial control: a review of their use in the past two decades","volume":"603","author":"Ramos","year":"2021","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0485","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.mib.2019.05.008","article-title":"Global epidemiology of emerging Candida auris","volume":"52","author":"Rhodes","year":"2019","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0330","article-title":"The multifunctional fungal ergostero","volume":"1\u20135","author":"Rodrigues","year":"2018","journal-title":"Am. Soc. Microbiol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0335","first-page":"51","article-title":"Galleria mellonella infection model as a system to investigate the virulence of Candida auris strains","volume":"78","author":"Romera","year":"2012","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0340","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/femspd\/ftaa067","article-title":"The galleria mellonella infection model as a system to investigate the virulence of Candida auris strains","volume":"78","author":"Romera","year":"2020","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0345","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3390\/microorganisms8020181","article-title":"Candida auris, an agent of hospital-associated outbreaks: which challenging issues do we need to have in mind?","volume":"8","author":"Sabino","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0360","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1021\/j100155a091","article-title":"Lecithin-based microemulsions: phase behavior and microstructure","volume":"95","author":"Shinoda","year":"1991","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0365","doi-asserted-by":"crossref","first-page":"22534","DOI":"10.3390\/molecules201219822","article-title":"A nanostructured lipid system as a strategy to improve the in vitro antibacterial activity of copper(II) complexes","volume":"20","author":"Silva","year":"2015","journal-title":"Molecules"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0375","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jconrel.2017.03.008","article-title":"Nanoemulsion: concepts, development and applications in drug delivery","volume":"252","author":"Singh","year":"2017","journal-title":"J. Control. Release"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0380","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1016\/j.nano.2017.06.021","article-title":"Amphotericin B releasing topical nanoemulsion for the treatment of candidiasis and aspergillosis","volume":"13","author":"Sosa","year":"2017","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0390","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1080\/10837450.2016.1221431","article-title":"Nonionic surfactant structure on the drug release, formulation and physical properties of ethylcellulose microspheres","volume":"22","author":"Thakare","year":"2017","journal-title":"Pharm. Dev. Technol."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0400","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1080\/21505594.2015.1135289","article-title":"Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing","volume":"7","author":"Tsai","year":"2016","journal-title":"Virulence"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0405","doi-asserted-by":"crossref","first-page":"495","DOI":"10.2174\/1381612822666161027111957","article-title":"Challenges and future prospects of nanoemulsion as a drug delivery system","volume":"23","author":"Yukuyama","year":"2016","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.scitotenv.2021.151023_bb0410","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1208\/s12249-021-02006-w","article-title":"[10]-gingerol-loaded nanoemulsion and its biological effects on triple-negative breast cancer cells","volume":"22","author":"Zanesco-Fontes","year":"2021","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.scitotenv.2021.151023_bb0415","series-title":"Overview of Nanoemulsion Properties: Stability, Rheology, and Appearance, Nanoemulsions: Formulation, Applications, and Characterization","author":"Zhang","year":"2018"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721061015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721061015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T13:37:05Z","timestamp":1758721025000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969721061015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":72,"alternative-id":["S0048969721061015"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.151023","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Galleria mellonella for systemic assessment of anti-Candida auris using amphotericin B loaded in nanoemulsion","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.151023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"151023"}}