{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:46:25Z","timestamp":1777581985623,"version":"3.51.4"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T00:00:00Z","timestamp":1637107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014440","name":"Gobierno de Espa\u00f1a Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["CGL2017-92160-EXP"],"award-info":[{"award-number":["CGL2017-92160-EXP"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Gobierno de Espa\u00f1a Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PID2019-105868RA-I00"],"award-info":[{"award-number":["PID2019-105868RA-I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Gobierno de Espa\u00f1a Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["RYC-2017-22324"],"award-info":[{"award-number":["RYC-2017-22324"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BD\/135793\/2018"],"award-info":[{"award-number":["SFRH\/BD\/135793\/2018"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["2017-92160-EXP"],"award-info":[{"award-number":["2017-92160-EXP"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["2019-105868RA-I00"],"award-info":[{"award-number":["2019-105868RA-I00"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009091","name":"Fundaci\u00f3 Catalana de Trasplantament","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009091","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.scitotenv.2021.151713","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T05:26:32Z","timestamp":1637126792000},"page":"151713","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Are habitable clean areas in heterogeneously contaminated landscapes functioning as escape zones for fish populations to alleviate stress?"],"prefix":"10.1016","volume":"818","author":[{"given":"Cristiano V.M.","family":"Ara\u00fajo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Sendra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Rodolfo S.","family":"Pontes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Trombini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juli\u00e1n","family":"Blasco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2021.151713_bb0005","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.envpol.2005.04.020","article-title":"Island biogeography and landscape structure: integrating ecological concepts in a landscape perspective of anthropogenic impacts in temporary wetlands","volume":"138","author":"Angeler","year":"2005","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0010","series-title":"Standard Methods for the Examination of Water and Wastewater","first-page":"386","author":"APHA","year":"1995"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0015","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.scitotenv.2018.06.264","article-title":"Stressor-driven emigration and recolonisation patterns in disturbed habitats","volume":"643","author":"Ara\u00fajo","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114545","article-title":"Contamination may induce behavioural plasticity in the habitat selection by shrimps: a cost-benefits balance involving contamination, shelter and predation","volume":"263","author":"Ara\u00fajo","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0025","doi-asserted-by":"crossref","first-page":"790","DOI":"10.2307\/2269484","article-title":"Developing a field of landscape ecotoxicology","volume":"6","author":"Cairns","year":"1996","journal-title":"Ecol. Appl."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0030","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1897\/02-202","article-title":"The spatial extent of contaminants and the landscape scale: an analysis of the wildlife, conservation biology, and population modeling literature","volume":"23","author":"Carlsen","year":"2004","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0035","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1897\/09-140.1","article-title":"Community responses to contaminants: using basic ecological principles to predict ecotoxicological effects","volume":"28","author":"Clements","year":"2009","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0040","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1023\/B:HYDR.0000041606.80236.d6","volume":"526","author":"Dawidowicz","year":"2004","journal-title":"Hydrobiologia"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0045","doi-asserted-by":"crossref","first-page":"3871","DOI":"10.1016\/j.scitotenv.2009.11.009","article-title":"Ecological vulnerability in risk assessment - a review and perspectives","volume":"408","author":"De Lange","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0050","series-title":"Behavioral Ecology","first-page":"1810","article-title":"Habitat selection and habitat suitability preferences","author":"Doligez","year":"2008"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0055","first-page":"502","article-title":"Why conservation biology can benefit from sensory ecology","volume":"4","author":"Dominoni","year":"2020"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0060","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0048-9697(03)00141-4","article-title":"Indirect effects of contaminants in aquatic ecosystems","volume":"317","author":"Fleeger","year":"2003","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0065","first-page":"41","article-title":"Metapopulation dynamics","volume":"396","author":"Hanski","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0070","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/BF00212086","article-title":"Impaired cortisol stress response in fish from environments polluted by PAHs, PCBs, and mercury","volume":"22","author":"Hontela","year":"1992","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0075","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.scitotenv.2018.10.375","article-title":"Spatial avoidance, inhibition of recolonization and population isolation in zebrafish (Danio rerio) caused by copper exposure under a non-forced approach","volume":"653","author":"Islam","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0080","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1080\/20028091056773","article-title":"Landscape ecotoxicology and assessment of risk at multiple scales","volume":"8","author":"Johnson","year":"2002","journal-title":"Hum. Ecol. Risk. Assess."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0085","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1139\/f00-118","article-title":"Interrenal metallothionein and cortisol secretion in relation to Cd, Cu, and Zn exposure in yellow perch, Perca flavescens, from Abitibi lakes","volume":"57","author":"Laflamme","year":"2000","journal-title":"Can. J. Fish. Aquat. Sci."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0090","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1897\/03-231","article-title":"Avoidance of copper contamination by field populations of Daphnia longispina","volume":"23","author":"Lopes","year":"2004","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0095","series-title":"The Theory of Island Biogeography","author":"MacArthur","year":"1967"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0100","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/etc.2045","article-title":"Combined and interactive effects of global climate change and toxicants on populations and communities","volume":"32","author":"Moe","year":"2013","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0105","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1023\/A:1008924418720","article-title":"Cortisol in teleosts: dynamics, mechanisms of action, and metabolic regulation","volume":"9","author":"Mommsen","year":"1999","journal-title":"Rev. Fish Biol. Fish."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0110","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1897\/07-094.1","article-title":"Avoidance tests with small fish: determination of the median avoidance concentration and of the lowest observed-effect gradient","volume":"27","author":"Moreira-Santos","year":"2008","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0115","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1080\/10643389.2018.1564507","article-title":"What if aquatic animals move away from pesticide-contaminated habitats before suffering adverse physiological effects? A critical review","volume":"49","author":"Moreira-Santos","year":"2019","journal-title":"Crit. Rev. Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0120","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/cz\/zox010","article-title":"Integrative behavioral ecotoxicology: bringing together fields to establish new insight to behavioral ecology, toxicology, and conservation","volume":"63","author":"Peterson","year":"2017","journal-title":"Curr. Zool."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0125","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1007\/s10646-013-1070-0","article-title":"Contaminant driven genetic erosion and associated hypotheses on alleles loss, reduced population growth rate and increased susceptibility to future stressors: an essay","volume":"22","author":"Ribeiro","year":"2013","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0130","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/ieam.1839","article-title":"Latin America protected areas: protected from chemical pollution?","volume":"13","author":"Rodr\u00edguez-Jorquera","year":"2017","journal-title":"Integr. Environ. Assess. Manag."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0135","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1303\/aez.33.339","article-title":"Probit analysis of preference data","volume":"3","author":"Sakuma","year":"1998","journal-title":"Appl. Entomol. Zool."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0140","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1111\/1365-2664.13054","article-title":"Metacommunities, metaecosystems and the environmental fate of chemical contaminants","volume":"55","author":"Schiesari","year":"2018","journal-title":"J. Appl. Ecol."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0145","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.scitotenv.2018.06.127","article-title":"Influence of interspecific interactions on avoidance response to contamination","volume":"642","author":"Silva","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0150","first-page":"189","article-title":"Development of a whole-body cortisol extraction procedure for determination of stress in golden shiners,Notemigonus crysoleucas","volume":"33","author":"Sink","year":"2007"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0155","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1002\/etc.5620170828","article-title":"Metapopulation dynamics: indirect effects and multiple distinct outcomes in ecological risk assessment","volume":"17","author":"Spromberg","year":"1998","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0160","first-page":"281","article-title":"Effects of copper on the acute cortisol response and associated physiology in rainbow trout","volume":"155","author":"Tellis","year":"2012"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0165","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.aquatox.2016.02.021","article-title":"Chemical avoidance responses of fishes","volume":"174","author":"Tierney","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0170","first-page":"1","article-title":"Evidence for behavioral preference toward environmental concentrations of urban-use herbicides in a model adult fish","volume":"9999","author":"Tierney","year":"2011","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0175","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.scitotenv.2019.01.304","article-title":"Habitat selection response of the freshwater shrimp Atyaephyra desmarestii experimentally exposed to heterogeneous copper contamination scenarios","volume":"662","author":"Vera-Vera","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.151713_bb0180","series-title":"Environmental Physiology of Animals","first-page":"644","author":"Willmer","year":"2000"},{"key":"10.1016\/j.scitotenv.2021.151713_bb0185","first-page":"10","article-title":"Impairment of the cortisol stress response mediated by thehypothalamus\u2013pituitary\u2013interrenal (HPI) axis in zebrafish (Danio rerio) exposed to monocrotophos pesticide","volume":"176\u2013177","author":"Zhang","year":"2015"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721067899?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721067899?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T13:46:35Z","timestamp":1758721595000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969721067899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":37,"alternative-id":["S0048969721067899"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.151713","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Are habitable clean areas in heterogeneously contaminated landscapes functioning as escape zones for fish populations to alleviate stress?","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.151713","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"151713"}}