{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T19:39:36Z","timestamp":1792697976221,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T00:00:00Z","timestamp":1643760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill & Melinda Gates Foundation","doi-asserted-by":"publisher","award":["INV-016826"],"award-info":[{"award-number":["INV-016826"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["19ykzd16"],"award-info":[{"award-number":["19ykzd16"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013804","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013804","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.scitotenv.2021.152789","type":"journal-article","created":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T06:51:24Z","timestamp":1641279084000},"page":"152789","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"special_numbering":"C","title":["Interactive effects of cold spell and air pollution on outpatient visits for anxiety in three subtropical Chinese cities"],"prefix":"10.1016","volume":"817","author":[{"given":"Huan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengmin (Min)","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zilong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chongjian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren D.","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen Edward","family":"McMillin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaowei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hualiang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2021.152789_bb0005","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.scitotenv.2016.06.030","article-title":"The cold effects on circulatory inflammation, thrombosis and vasoconstriction in type 2 diabetic patients","volume":"568","author":"Cai","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0010","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.envint.2018.04.021","article-title":"Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight european urban areas","volume":"116","author":"Chen","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0015","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.envint.2019.04.049","article-title":"Cold spell and mortality in 31 Chinese capital cities: definitions, vulnerability and implications","volume":"128","author":"Chen","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143218","article-title":"Associations of adverse pregnancy outcomes with high ambient air pollution exposure: results from the project ELEFANT","volume":"761","author":"Chen","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.136315","article-title":"Short-term effects of traffic noise on suicides and emergency hospital admissions due to anxiety and depression in Madrid (Spain)","volume":"710","author":"Diaz","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0030","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/00016480252814207","article-title":"An explanation for the seasonality of acute upper respiratory tract viral infections","volume":"122","author":"Eccles","year":"2002","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0035","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.eurpsy.2017.02.492","article-title":"Particulate matter air pollution associated with hospital admissions for mental disorders: a time-series study in Beijing","volume":"44","author":"Gao","year":"2017","journal-title":"China. Eur Psychiatry"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0040","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/S0140-6736(20)30925-9","article-title":"Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"396","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0045","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1176\/appi.ajp.2020.19070748","article-title":"Association between ambient air pollution and daily hospital admissions for depression in 75 Chinese cities","volume":"177","author":"Gu","year":"2020","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0050","doi-asserted-by":"crossref","first-page":"28033","DOI":"10.1038\/srep28033","article-title":"Meta-analysis of the prevalence of anxiety disorders in mainland China from 2000 to 2015","volume":"6","author":"Guo","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0055","doi-asserted-by":"crossref","DOI":"10.1289\/EHP1026","article-title":"Heat wave and mortality: a multicountry, multicommunity study","volume":"125","author":"Guo","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0060","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1289\/ehp.11339","article-title":"The effect of heat waves on mental health in a temperate Australian city","volume":"116","author":"Hansen","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0065","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1152\/japplphysiol.00916.2004","article-title":"Inhibition of the preoptic area and anterior hypothalamus by tetrodotoxin alters thermoregulatory functions in exercising rats","volume":"98","author":"Hasegawa","year":"2005","journal-title":"J. Appl. Physiol. (1985)"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0070","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-009172","article-title":"Individual-level and community-level effect modifiers of the temperature-mortality relationship in 66 chinese communities","volume":"5","author":"Huang","year":"2015","journal-title":"BMJ Open"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0075","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1289\/ehp.1307262","article-title":"Heat waves and health outcomes in Alabama (USA): the importance of heat wave definition","volume":"122","author":"Kent","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0080","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1093\/ije\/dyr218","article-title":"Recommendations for presenting analyses of effect modification and interaction","volume":"41","author":"Knol","year":"2012","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0085","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1093\/ije\/dym157","article-title":"Estimating interaction on an additive scale between continuous determinants in a logistic regression model","volume":"36","author":"Knol","year":"2007","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0090","doi-asserted-by":"crossref","first-page":"529","DOI":"10.5194\/essd-13-529-2021","article-title":"A 6-year-long (2013\u20132018) high-resolution air quality reanalysis dataset in China based on the assimilation of surface observations from CNEMC","volume":"13","author":"Kong","year":"2021","journal-title":"Earth Syst. Sci. Data"},{"issue":"Suppl. 14","key":"10.1016\/j.scitotenv.2021.152789_bb0095","first-page":"4","article-title":"The epidemiology of anxiety disorders: prevalence and societal costs","volume":"63","author":"L\u00e9pine","year":"2002","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.110214","article-title":"Short-term effects of air pollution on cause-specific mental disorders in three subtropical Chinese cities","volume":"191","author":"Li","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0105","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.scitotenv.2018.06.026","article-title":"Effect of the 2008 cold spell on preterm births in two subtropical cities of Guangdong Province, southern China","volume":"642","author":"Liang","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0110","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1164\/rccm.201810-1823OC","article-title":"Short-term exposure to ambient air pollution and asthma mortality","volume":"200","author":"Liu","year":"2019","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0115","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jacc.2020.11.033","article-title":"Short-term exposure to ambient air pollution and mortality from myocardial infarction","volume":"77","author":"Liu","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113030","article-title":"Short-term exposure to air pollution and conjunctivitis outpatient visits: a multi-city study in China","volume":"254","author":"Lu","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105906","article-title":"Attributable risks associated with hospital outpatient visits for mental disorders due to air pollution: A multi-city study in China","volume":"143","author":"Lu","year":"2020","journal-title":"Environment international"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0130","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1080\/00140139.2012.665497","article-title":"Acute cold exposure and cognitive function: evidence for sustained impairment","volume":"55","author":"Muller","year":"2012","journal-title":"Ergonomics"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0135","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.envres.2018.12.019","article-title":"Attributable risk of hospital admissions for overall and specific mental disorders due to particulate matter pollution: a time-series study in ChengduChina","volume":"170","author":"Qiu","year":"2019","journal-title":"Environ Res"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0140","series-title":"Epidemiology: An Introduction","author":"Rothman","year":"2002"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0145","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1192\/bjp.2020.73","article-title":"Extending the vulnerability-stress model of mental disorders: three-dimensional NPSR1 \u00d7 environment \u00d7 coping interaction study in anxiety","volume":"217","author":"Schiele","year":"2020","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0150","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.scitotenv.2018.04.187","article-title":"Acute effects of ambient particulate matter pollution on hospital admissions for mental and behavioral disorders: a time-series study in ShijiazhuangChina.","volume":"636","author":"Song","year":"2018","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0155","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.scitotenv.2011.09.028","article-title":"Relationship between mean daily ambient temperature range and hospital admissions for schizophrenia: results from a national cohort of psychiatric inpatients","volume":"410\u2013411","author":"Sung","year":"2011","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0160","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.scitotenv.2015.09.066","article-title":"Season, sex and age as modifiers in the association of psychosis morbidity with air pollutants: a rising problem in a chinese metropolis","volume":"541","author":"Tong","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0165","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jad.2013.10.042","article-title":"Acute impacts of extreme temperature exposure on emergency room admissions related to mental and behavior disorders in TorontoCanada","volume":"155","author":"Wang","year":"2014","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0170","doi-asserted-by":"crossref","first-page":"17006","DOI":"10.1289\/EHP5117","article-title":"Independent and combined effects of heatwaves and PM2.5 on preterm birth in Guangzhou, China: a survival analysis","volume":"128","author":"Wang","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002950","article-title":"The association between heat exposure and hospitalization for undernutrition in Brazil during 2000\u20132015: a nationwide case-crossover study","volume":"16","author":"Xu","year":"2019","journal-title":"PLoS Med."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0180","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.scitotenv.2018.08.332","article-title":"Heatwave and mortality in 31 major Chinese cities: definition, vulnerability and implications","volume":"649","author":"Yang","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105589","article-title":"Associations of long-term exposure to ambient PM(2.5) with mortality in chinese adults: a pooled analysis of cohorts in the China-PAR project","volume":"138","author":"Yang","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2021.152789_bb0190","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijheh.2019.09.006","article-title":"Association between ambient particulate matter and hospitalization for anxiety in China: a multicity case-crossover study","volume":"223","author":"Yue","year":"2020","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.scitotenv.2021.152789_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105938","article-title":"The effect of temperature on cause-specific mental disorders in three subtropical cities: a case-crossover study in China","volume":"143","author":"Zhang","year":"2020","journal-title":"Environ. Int."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721078682?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969721078682?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T16:25:43Z","timestamp":1750782343000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969721078682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":39,"alternative-id":["S0048969721078682"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.152789","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interactive effects of cold spell and air pollution on outpatient visits for anxiety in three subtropical Chinese cities","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2021.152789","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"152789"}}