{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:07:08Z","timestamp":1792602428249,"version":"4.5.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003141","name":"National Council on Science and Technology","doi-asserted-by":"publisher","award":["300727"],"award-info":[{"award-number":["300727"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.scitotenv.2022.154689","type":"journal-article","created":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T20:19:46Z","timestamp":1647634786000},"page":"154689","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Acute exposure to environmentally relevant concentrations of sucralose disrupts embryonic development and leads to an oxidative stress response in Danio rerio"],"prefix":"10.1016","volume":"829","author":[{"given":"Karla","family":"Col\u00edn-Garc\u00eda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Axel","family":"Elizalde-Vel\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leobardo Manuel","family":"G\u00f3mez-Oliv\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hariz","family":"Islas-Flores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Garc\u00eda-Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Galar-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.scitotenv.2022.154689_bb0005","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1016\/j.biocel.2010.06.001","article-title":"The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes","volume":"42","author":"Al-Gubory","year":"2010","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0010","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.chroma.2015.03.035","article-title":"Determination of high-intensity sweeteners in river water and wastewater by solid-phase extraction and liquid chromatography\u2013tandem mass spectrometry","volume":"1393","author":"Arbel\u00e1ez","year":"2015","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0015","series-title":"The Effect of Sugar and Sucralose on the Embryonic Development of Zebrafish","author":"Arndorfer","year":"2018"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0020","first-page":"1","article-title":"Nrf2 and oxidative stress in hepatic ischemia\/reperfusion injury","author":"Bardallo","year":"2021","journal-title":"FEBS J."},{"issue":"5","key":"10.1016\/j.scitotenv.2022.154689_bb0025","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.chemosphere.2012.03.030","article-title":"Stability considerations of aspartame in the direct analysis of artificial sweeteners in water samples using high-performance liquid chromatography\u2013tandem mass spectrometry (HPLC\u2013MS\/MS)","volume":"88","author":"Berset","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0030","doi-asserted-by":"crossref","first-page":"487","DOI":"10.3389\/fphys.2017.00487","article-title":"Gut microbiome response to sucralose and its potential role in inducing liver inflammation in mice","volume":"8","author":"Bian","year":"2017","journal-title":"Front. Physiol."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0035","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.scitotenv.2019.02.279","article-title":"Sorption and degradation of contaminants of emerging concern in soils under aerobic and anaerobic conditions","volume":"666","author":"Biel-Maeso","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0040","article-title":"Sucralose stimulates mitochondrial bioenergetics in Caco-2 cells","volume":"361","author":"B\u00f3rquez","year":"2021","journal-title":"FrontiersNutrition"},{"issue":"1\u20132","key":"10.1016\/j.scitotenv.2022.154689_bb2000","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0045","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0076-6879(78)52032-6","article-title":"[30] Microsomal lipid peroxidation","volume":"52","author":"Buege","year":"1978"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0050","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.marpolbul.2019.07.036","article-title":"Evaluation of the artificial sweetener sucralose as a sanitary wastewater tracer in Narragansett Bay, Rhode Island, USA","volume":"146","author":"Cantwell","year":"2019","journal-title":"Mar. Pollut. Bull."},{"issue":"3","key":"10.1016\/j.scitotenv.2022.154689_bb0060","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/bdrc.20098","article-title":"Effects of oxidative stress on embryonic development","volume":"81","author":"Dennery","year":"2007","journal-title":"Birth Defects Res. C Embryo Today"},{"issue":"338","key":"10.1016\/j.scitotenv.2022.154689_bb0065","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.morpho.2018.07.003","article-title":"A histological assessment of effects of sucralose on liver of albino rats","volume":"102","author":"Dhurandhar","year":"2018","journal-title":"Morphologie"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131213","article-title":"Antidiabetic drug metformin disrupts the embryogenesis in zebrafish through an oxidative stress mechanism","volume":"285","author":"Elizalde-Vel\u00e1zquez","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149432","article-title":"Oxidative stress as a potential mechanism by which guanylurea disrupts the embryogenesis of Danio rerio","volume":"799","author":"Elizalde-Vel\u00e1zquez","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"819","key":"10.1016\/j.scitotenv.2022.154689_bb3000","article-title":"Chronic exposure to environmentally relevant concentrations of guanylurea induces neurotoxicity of Danio rerio adults","author":"Elizalde-Vel\u00e1zquez","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"4","key":"10.1016\/j.scitotenv.2022.154689_bb0085","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0092771","article-title":"Sucralose induces biochemical responses in Daphnia magna","volume":"9","author":"Eriksson Wiklund","year":"2014","journal-title":"PloS one"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0090","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.chemosphere.2018.03.049","article-title":"Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos","volume":"201","author":"F\u00e9lix","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2019.109980","article-title":"Sucralose and acesulfame as an indicator of domestic wastewater contamination in Wuhan surface water","volume":"189","author":"Fu","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0100","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.chroma.2012.11.081","article-title":"A novel solid-phase extraction for the concentration of sweeteners in water and analysis by ion-pair liquid chromatography\u2013triple quadrupole mass spectrometry","volume":"1274","author":"Gan","year":"2013","journal-title":"J. Chromatogr. A"},{"issue":"14","key":"10.1016\/j.scitotenv.2022.154689_bb0105","doi-asserted-by":"crossref","first-page":"4928","DOI":"10.1016\/j.watres.2013.05.038","article-title":"Occurrence of seven artificial sweeteners in the aquatic environment and precipitation of Tianjin China","volume":"47","author":"Gan","year":"2013","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0115","doi-asserted-by":"crossref","first-page":"435","DOI":"10.3389\/fgene.2019.00435","article-title":"Regulation of mitochondrial biogenesis as a way for active longevity: interaction between the Nrf2 and PGC-1\u03b1 signaling pathways","volume":"10","author":"Gureev","year":"2019","journal-title":"Front. Genet."},{"issue":"4","key":"10.1016\/j.scitotenv.2022.154689_bb9000","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/bdrc.20085","article-title":"Oxidative stress as a mechanism of teratogenesis","volume":"78","author":"Hansen","year":"2006","journal-title":"Birth Defects Res. C Embryo Today"},{"issue":"15","key":"10.1016\/j.scitotenv.2022.154689_bb0120","doi-asserted-by":"crossref","first-page":"5378","DOI":"10.3390\/ijms21155378","article-title":"Molecular mechanisms underlying hepatocellular carcinoma induction by aberrant NRF2 activation-mediated transcription networks: interaction of NRF2-KEAP1 controls the fate of hepatocarcinogenesis","volume":"21","author":"Haque","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0125","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.scitotenv.2019.07.165","article-title":"Alterations to DNA, apoptosis and oxidative damage induced by sucralose in blood cells of Cyprinus Carpio","volume":"692","author":"Heredia-Garc\u00eda","year":"2019","journal-title":"Sci. Total Environ."},{"issue":"2","key":"10.1016\/j.scitotenv.2022.154689_bb0130","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/0003-2697(92)90122-N","article-title":"Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein","volume":"202","author":"Jiang","year":"1992","journal-title":"Anal. Biochem."},{"issue":"2","key":"10.1016\/j.scitotenv.2022.154689_bb4000","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.fsi.2014.09.037","article-title":"Embryonic exposure to carbendazim induces the transcription of genes related to apoptosis, immunotoxicity and endocrine disruption in zebrafish (Danio rerio)","volume":"41","author":"Jiang","year":"2014","journal-title":"Fish Shellfish Immunol."},{"issue":"13","key":"10.1016\/j.scitotenv.2022.154689_bb0135","doi-asserted-by":"crossref","first-page":"6799","DOI":"10.1021\/es304339u","article-title":"Re-engineering an artificial sweetener: transforming sucralose residuals in water via advanced oxidation","volume":"47","author":"Keen","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2022.154689_bb5000","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0140","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S0076-6879(94)33040-9","article-title":"[37] carbonyl assays for determination of oxidatively modified proteins","volume":"233","author":"Levine","year":"1994","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.142438","article-title":"Trends in artificial sweetener consumption: a 7-year wastewater-based epidemiology study in Queensland Australia","volume":"754","author":"Li","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"4","key":"10.1016\/j.scitotenv.2022.154689_bb0160","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2-\u0394 \u0394Ct method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0165","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.scitotenv.2018.10.445","article-title":"Ecotoxicity and environmental fates of newly recognized contaminants-artificial sweeteners: a review","volume":"653","author":"Luo","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0170","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.fct.2017.05.047","article-title":"Critical review of the current literature on the safety of sucralose","volume":"106","author":"Magnuson","year":"2017","journal-title":"Food Chem. Toxicol."},{"issue":"10","key":"10.1016\/j.scitotenv.2022.154689_bb0175","doi-asserted-by":"crossref","first-page":"3170","DOI":"10.1016\/S0021-9258(19)45228-9","article-title":"The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase","volume":"247","author":"Misra","year":"1972","journal-title":"J. Biol. Chem."},{"issue":"13","key":"10.1016\/j.scitotenv.2022.154689_bb0185","doi-asserted-by":"crossref","first-page":"4019","DOI":"10.1016\/j.watres.2011.05.014","article-title":"Occurrence and suitability of sucralose as an indicator compound of wastewater loading to surface waters in urbanized regions","volume":"45","author":"Oppenheimer","year":"2011","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0190","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.chroma.2012.07.073","article-title":"Determination of artificial sweeteners in water samples by solid-phase extraction and liquid chromatography\u2013tandem mass spectrometry","volume":"1256","author":"Ord\u00f3\u00f1ez","year":"2012","journal-title":"J. Chromatogr. A"},{"issue":"10","key":"10.1016\/j.scitotenv.2022.154689_bb0195","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1111\/1440-1681.13362","article-title":"Sucralose causes non-selective CD4 and CD8 lymphotoxicity via probable regulation of the MAPK8\/APTX\/EID1 genes: An in vitro\/in silico study","volume":"47","author":"Pasqualli","year":"2020","journal-title":"Clinical and Experimental Pharmacology and Physiology"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0200","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.envpol.2013.09.017","article-title":"Quantification of four artificial sweeteners in finnish surface waters with isotope-dilution mass spectrometry","volume":"184","author":"Perkola","year":"2014","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0205","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.ecoenv.2018.12.048","article-title":"Non-nutritive artificial sweeteners as an emerging contaminant in environment: a global review and risks perspectives","volume":"170","author":"Praveena","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"32","key":"10.1016\/j.scitotenv.2022.154689_bb0210","doi-asserted-by":"crossref","first-page":"22028","DOI":"10.1016\/S0021-9258(18)54740-2","article-title":"Detection of catalase in rat heart mitochondria","volume":"266","author":"Radi","year":"1991","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.scitotenv.2022.154689_bb0215","doi-asserted-by":"crossref","first-page":"538","DOI":"10.2174\/1568009617666171002144228","article-title":"Oxidative stress and cancer: the role of Nrf2","volume":"18","author":"Sajadimajd","year":"2018","journal-title":"Curr. Cancer Drug Targets"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0225","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.watres.2013.11.002","article-title":"Evaluating the environmental impact of artificial sweeteners: a study of their distributions, photodegradation and toxicities","volume":"52","author":"Sang","year":"2014","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0230","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.redox.2017.05.023","article-title":"The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo","volume":"13","author":"Sant","year":"2017","journal-title":"Redox Biol."},{"issue":"6","key":"10.1016\/j.scitotenv.2022.154689_bb0235","doi-asserted-by":"crossref","first-page":"548","DOI":"10.3390\/biology10060548","article-title":"Acute and sub-chronic exposure to artificial sweeteners at the highest environmentally relevant concentration induce less cardiovascular physiology alterations in zebrafish larvae","volume":"10","author":"Saputra","year":"2021","journal-title":"Biology"},{"key":"10.1016\/j.scitotenv.2022.154689_bb0240","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.scitotenv.2016.09.230","article-title":"Toxicological hazard induced by sucralose to environmentally relevant concentrations in common carp (Cyprinus carpio)","volume":"575","author":"Saucedo-Vence","year":"2017","journal-title":"Sci. Total Environ."},{"issue":"12","key":"10.1016\/j.scitotenv.2022.154689_bb0245","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.watres.2010.04.005","article-title":"Performance of conventional multi-barrier drinking water treatment plants for the removal of four artificial sweeteners","volume":"44","author":"Scheurer","year":"2010","journal-title":"Water Res."},{"issue":"7","key":"10.1016\/j.scitotenv.2022.154689_bb6000","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/10937404.2013.842523","article-title":"Sucralose, a synthetic organochlorine sweetener: overview of biological issues","volume":"16","author":"Schiffman","year":"2013","journal-title":"J. Toxicol. Environ. Health, Part B"},{"issue":"3","key":"10.1016\/j.scitotenv.2022.154689_bb0250","doi-asserted-by":"crossref","first-page":"541","DOI":"10.3390\/cancers13030541","article-title":"Roles of CNC transcription factors NRF1 and NRF2 in cancer","volume":"13","author":"Sekine","year":"2021","journal-title":"Cancers"},{"issue":"4","key":"10.1016\/j.scitotenv.2022.154689_bb0255","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1021\/es102719d","article-title":"Fate of sucralose through environmental and water treatment processes and impact on plant indicator species","volume":"45","author":"Soh","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0260","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.chemosphere.2019.06.041","article-title":"Mass loads, source apportionment, and risk estimation of organic micropollutants from hospital and municipal wastewater in recipient catchments","volume":"234","author":"S\u00f6reng\u00e5rd","year":"2019","journal-title":"Chemosphere"},{"issue":"4","key":"10.1016\/j.scitotenv.2022.154689_bb0265","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s00128-014-1348-9","article-title":"Early life stage (ELS) toxicity of sucralose to fathead minnows, Pimephales promelas","volume":"93","author":"Stoddard","year":"2014","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0270","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.scitotenv.2012.08.060","article-title":"Presence, fate and effects of the intense sweetener sucralose in the aquatic environment","volume":"438","author":"Tollefsen","year":"2012","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0275","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.talanta.2013.03.072","article-title":"Simultaneous determination of PPCPs, EDCs, and artificial sweeteners in environmental water samples using a single-step SPE coupled with HPLC\u2013MS\/MS and isotope dilution","volume":"113","author":"Tran","year":"2013","journal-title":"Talanta"},{"issue":"1","key":"10.1016\/j.scitotenv.2022.154689_bb0280","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/vjch.202000094","article-title":"Effect of stabilizing and brightening agents and some operated conditions on electroplating kinetics of NiCu alloys from citrate-sulfate solutions","volume":"59","author":"Van Vy","year":"2021","journal-title":"Vietnam J. Chem."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0285","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/B978-0-12-374814-0.00024-0","article-title":"Aquaculture and husbandry at the zebrafish international resource center","volume":"104","author":"Varga","year":"2011","journal-title":"Methods Cell Biol."},{"issue":"1","key":"10.1016\/j.scitotenv.2022.154689_bb0290","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.cmet.2016.06.010","article-title":"Sucralose promotes food intake through NPY and a neuronal fasting response","volume":"24","author":"Wang","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.scitotenv.2022.154689_bb0295","series-title":"The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish Danio (\"Brachydanio Rerio\")","author":"Westerfield","year":"2007"},{"issue":"1","key":"10.1016\/j.scitotenv.2022.154689_bb0300","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.chemosphere.2011.08.049","article-title":"Sucralose\u2013an ecotoxicological challenger?","volume":"86","author":"Wiklund","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.154689_bb7000","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.cej.2018.07.090","article-title":"Performance of artificial sweetener sucralose mineralization via UV\/O3 process: kinetics, toxicity and intermediates","volume":"353","author":"Xu","year":"2018","journal-title":"Chem. Eng. J."},{"issue":"4","key":"10.1016\/j.scitotenv.2022.154689_bb0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.jece.2021.105293","article-title":"Sucralose, a persistent artificial sweetener in the urban water cycle: insights into occurrence, chlorinated byproducts formation, and human exposure","volume":"9","author":"Yang","year":"2021","journal-title":"J. Environ. Chem. Eng."},{"issue":"134","key":"10.1016\/j.scitotenv.2022.154689_bb1000","article-title":"Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction","volume":"13","author":"Ye","year":"2012","journal-title":"BMC Bioinf."},{"issue":"4","key":"10.1016\/j.scitotenv.2022.154689_bb0310","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/cr.2009.19","article-title":"Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1","volume":"19","author":"Zuo","year":"2009","journal-title":"Cell Res."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896972201782X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896972201782X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T17:01:49Z","timestamp":1785430909000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004896972201782X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":63,"alternative-id":["S004896972201782X"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2022.154689","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute exposure to environmentally relevant concentrations of sucralose disrupts embryonic development and leads to an oxidative stress response in Danio rerio","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2022.154689","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"154689"}}