{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:18:31Z","timestamp":1790083111478,"version":"4.0.1"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.scitotenv.2022.157025","type":"journal-article","created":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T02:00:47Z","timestamp":1656381647000},"page":"157025","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Differential biochemical and behavioral responses induced by cocaine and benzoylecgonine exposure to the red swamp crayfish Procambarus clarkii"],"prefix":"10.1016","volume":"844","author":[{"given":"Beatrice","family":"De Felice","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"De Pascalis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raoul","family":"Manenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radmila","family":"Pavlovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"di Cesare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Nasti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giangiacomo","family":"Beretta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Parolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2022.157025_bb0005","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1101\/gr.268037.120","article-title":"The Drosophila brain on cocaine at single-cell resolution","volume":"31","author":"Baker","year":"2021","journal-title":"Genome Res."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0010","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF00427356","article-title":"Effect of cocaine on food intake in rats","volume":"64","author":"Balopole","year":"1979","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0015","series-title":"Package \u2018lme4\u2019. Linear Mixed-effects Models Using S4 Classes. R Package Version","first-page":"6","volume":"1","author":"Bates","year":"2011"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0020","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/BF00350681","article-title":"Effect of the neurotransmitters dopamine, serotonin and norepinephrine on the ciliary activity of mussel (Mytilus edulis) larvae","volume":"122","author":"Beiras","year":"1995","journal-title":"Mar. Biol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0025","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.chemosphere.2011.10.056","article-title":"Illicit drugs as a new environmental pollutant: cyto-genotoxic effects of cocaine on the biological model Dreissena polymorpha","volume":"86","author":"Binelli","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0030","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0035","series-title":"Package \u2018visreg\u2019","author":"Breheny","year":"2020"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0040","doi-asserted-by":"crossref","first-page":"20130580","DOI":"10.1098\/rstb.2013.0580","article-title":"Ecological effects of pharmaceuticals in aquatic systems - impacts through behavioural alterations","volume":"369","author":"Brodin","year":"2014","journal-title":"Philos. Trans. R. Soc. Lond. B"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0045","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/S0022-3565(24)29587-2","article-title":"Electrophysiological effects of cocaethylene, cocaine, and ethanol on dopaminergic neurons of the ventral tegmental area","volume":"297","author":"Bunney","year":"2001","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0050","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.scitotenv.2018.05.357","article-title":"Effects of environmental cocaine concentrations on the skeletal muscle of the European eel (Anguilla anguilla)","volume":"640\u2013641","author":"Capaldo","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0055","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ecoenv.2018.11.010","article-title":"Changes in the gills of the european eel (Anguilla anguilla) after chronic exposure to environmental cocaine concentration","volume":"169","author":"Capaldo","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2022.157025_bb1000","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.scitotenv.2013.10.034","article-title":"Testing wastewater to detect illicit drugs: State of the art, potential and research needs","author":"Castiglioni","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0060","doi-asserted-by":"crossref","first-page":"248","DOI":"10.2307\/1548953","article-title":"Burrowing behavior of the introduced red swamp crayfish Procambarus clarkii (Decapoda: Cambaridae) in Portugal","volume":"15","author":"Correia","year":"1995","journal-title":"J. Crustac. Bio."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2020.103475","article-title":"Effects of single and combined exposure to cocaine and benzoylecgonine on the oxidative status of Mytilus galloprovincialis","volume":"80","author":"De Felice","year":"2020","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0070","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.scitotenv.2019.06.383","article-title":"Biochemical and behavioral effects induced by cocaine exposure to Daphnia magna","volume":"689","author":"De Felice","year":"2019","journal-title":"Sci. Tot. Environ."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.137728","article-title":"Methamphetamine exposure modulated oxidative status and altered the reproductive output in Daphnia magna","volume":"721","author":"De Felice","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.129430","article-title":"Dietary exposure to polyethylene terephthalate microplastics (PET-MPs) induces faster growth but not oxidative stress in the giant snail Achatina reticulata","volume":"270","author":"De Felice","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0085","series-title":"Behavioural Ecotoxicology","author":"Dell'Omo","year":"2002"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12302-020-00304-x","article-title":"Occurrence and removal of illicit drugs in different wastewater treatment plants with different treatment techniques","volume":"32","author":"Deng","year":"2020","journal-title":"Environ. Sci. Eur."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0095","first-page":"1","article-title":"Detoxification, oxidative stress, and cytogenotoxicity of crack cocaine in the brown mussel Perna perna","author":"dos Santos Barbosa Ortega","year":"2019","journal-title":"Environ. Sci. Poll. Res."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0100","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1071\/AM00125","article-title":"Observations of the behavior of ree-living bush rat, Rattus fuscipes and southern Brown Bandicoot, Isoodon obesulus at buried bait stations","volume":"22","author":"Fairbridge","year":"2000","journal-title":"Mamm. Austral."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0105","doi-asserted-by":"crossref","first-page":"30998","DOI":"10.1007\/s11356-020-08375-2","article-title":"Review on the occurrence and biological effects of illicit drugs in aquatic ecosystems","volume":"27","author":"Fontes","year":"2020","journal-title":"Environ. Sci. Pollut."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0110","doi-asserted-by":"crossref","first-page":"5620","DOI":"10.1021\/acs.est.0c06493","article-title":"The role of behavioral ecotoxicology in environmental protection","volume":"55","author":"Ford","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0115","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0197-0186(02)00080-3","article-title":"Effects of chronic variate stress on feeding behavior and on monoamine levels in different rat brain structures","volume":"42","author":"Gamaro","year":"2003","journal-title":"Neurochem. Internat."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0120","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.jhazmat.2015.08.019","article-title":"Environmental concentrations of the cocaine metabolite benzoylecgonine induced sublethal toxicity in the development of plants but not in a zebrafish embryo e larval model","volume":"300","author":"Garc\u00eda-Cambero","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0125","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1007\/s11270-013-1579-0","article-title":"Endocrine disruption in the european eel, Anguilla Anguilla, exposed to an environmental cocaine concentration","volume":"224","author":"Gay","year":"2013","journal-title":"Water Air Soil Poll."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0130","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/jfd.12362","article-title":"Histological and hormonal changes in the European eel (Anguilla anguilla) after exposure to environmental cocaine concentration","volume":"39","author":"Gay","year":"2016","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0135","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1111\/j.1365-2427.2007.01760.x","article-title":"Invasive crayfish in Europe: the impact of Procambarus clarkii on the littoral community of a Mediterranean lake","volume":"52","author":"Gherardi","year":"2007","journal-title":"Freshwater Bio."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0140","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s12021-016-9303-z","article-title":"AnimalTracker: an ImageJ-based tracking API to create a customized behaviour analyser program","volume":"14","author":"Guly\u00e0s","year":"2016","journal-title":"Neuroinf."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0145","first-page":"1","article-title":"Behavioral components of social interactions in the crayfish Procambarus gracilis (Bundy)(Decapoda: Cambaridae)","author":"Hayes","year":"1975","journal-title":"Proc. Oklahoma Acad. Sci."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.141383","article-title":"A combination of six psychoactive pharmaceuticals at environmental concentrations alter the locomotory behavior of clonal marbled crayfish","volume":"751","author":"Hossain","year":"2021","journal-title":"Sci. Tot. Environ."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0155","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.bbr.2017.05.069","article-title":"Effects of chronic cocaine, morphine and methamphetamine on the mobility, immobility and stereotyped behaviors in crayfish","volume":"332","author":"Imenh-Nathaniel","year":"2017","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0160","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.neures.2011.11.009","article-title":"Alteration of c-fos mRNA in the accessory lobe of crayfish is associated with a conditioned-cocaine induced reward","volume":"72","author":"Imenh-Nathaniel","year":"2012","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0165","series-title":"Oxidative Stress","author":"Kappus","year":"1985"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0170","article-title":"Thirty years of invasion: the distribution of the invasive crayfish Procambarus clarkii in Italy","volume":"35","author":"Lo Parrino","year":"2020","journal-title":"Biogeo. J. Integrat. Biogeo."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0175","doi-asserted-by":"crossref","first-page":"4465","DOI":"10.1021\/es062146p","article-title":"Behavioral and physiological changes in Daphnia magna when exposed to nanoparticle suspensions (titanium dioxide, nano-C60, and C60HxC70Hx)","volume":"41","author":"Lovern","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0180","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1179\/147683010X12611460764723","article-title":"Modulatory role of serotonin on feeding behavior","volume":"13","author":"Magalh\u00e3es","year":"2010","journal-title":"Nut. Neurosci."},{"issue":"2","key":"10.1016\/j.scitotenv.2022.157025_bb0185","article-title":"Package \u2018glmmTMB\u2019","author":"Magnusson","year":"2017","journal-title":"R Package Version"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0190","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.jnc.2014.09.001","article-title":"Austropotamobius pallipes reduction vs. Procambarus clarkii spreading: management implications","volume":"22","author":"Manenti","year":"2014","journal-title":"J. Nat. Conservat."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0195","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/01.ftd.0000211812.27558.6e","article-title":"Toxicokinetics of drugs of abuse: current knowledge of the isoenzymes involved in the human metabolism of tetrahydrocannabinola, cocaine, heroin, morphine, and codeine","volume":"28","author":"Maurer","year":"2006","journal-title":"Drug Monit."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0200","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1016\/j.chemosphere.2013.07.036","article-title":"The utility of behavioral studies for aquatic toxicology testing: a meta-analysis","volume":"93","author":"Melvin","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0205","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1080\/24750263.2020.1717653","article-title":"Accumulation of trace metals in crayfish tissues: is Procambarus clarkii a vector of pollutants in Po Delta inland waters?","volume":"87","author":"Mistri","year":"2020","journal-title":"Europ. Zool. J."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0210","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Biochemist"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0215","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.scitotenv.2012.05.086","article-title":"Illicit drugs and the environment","volume":"463\u2013464","author":"Pal","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0220","first-page":"41","article-title":"A pharmacological study of cocaine activity in planaria","volume":"115","author":"Palladini","year":"1996","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0225","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.tins.2007.06.004","article-title":"Is dopamine a physiologically relevant mediator of feeding behavior?","volume":"30","author":"Palmiter","year":"2007","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0230","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.scitotenv.2012.11.076","article-title":"Sub-lethal effects caused by the cocaine metabolite benzoylecgonine to the freshwater mussel Dreissena polymorpha","volume":"444","author":"Parolini","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0235","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.envpol.2017.04.046","article-title":"Environmental concentrations of cocaine and its main metabolites modulated antioxidant response and caused cyto-genotoxic effects in zebrafish embryo cells","volume":"226","author":"Parolini","year":"2017","journal-title":"Environ. Poll."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0240","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.envpol.2017.09.097","article-title":"Exposure to cocaine and its main metabolites altered the protein profile of zebrafish embryos","volume":"232","author":"Parolini","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0245","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.envpol.2017.09.038","article-title":"Benzoylecgonine exposure induced oxidative stress and altered swimming behavior and reproduction in Daphnia magna","volume":"232","author":"Parolini","year":"2018","journal-title":"Environ. Poll."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0250","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/dta.1409","article-title":"A redox proteomic investigation of oxidative stress caused by benzoylecgonine in the freshwater bivalve Dreissena polymorpha","volume":"5","author":"Pedriali","year":"2013","journal-title":"Drug Test. Anal."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0255","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s12640-015-9536-x","article-title":"A comprehensive view of the neurotoxicity mechanisms of cocaine and ethanol","volume":"28","author":"Pereira","year":"2015","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0260","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.aquatox.2016.11.008","article-title":"Behaviour revised: contaminant effects on aquatic animal behaviour","volume":"182","author":"Pyle","year":"2017","journal-title":"Aquatic Toxicol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0265","doi-asserted-by":"crossref","first-page":"4717","DOI":"10.1074\/jbc.M008067200","article-title":"Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter","volume":"276","author":"Rasmussen","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scitotenv.2022.157025_bb2000","series-title":"R Foundation for Statistical Computing","article-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2020"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0270","doi-asserted-by":"crossref","first-page":"5624","DOI":"10.2174\/092986712803988893","article-title":"Side effects of cocaine abuse: multiorgan toxicity and pathological consequences","volume":"19","author":"Riezzo","year":"2012","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0275","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s11064-018-2485-z","article-title":"The leptin, dopamine and serotonin receptors in hypothalamic POMC-neurons of normal and obese rodents","volume":"43","author":"Romanova","year":"2018","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0280","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jhazmat.2014.06.062","article-title":"A review of ecological effects and environmental fate of illicit drugs in aquatic ecosystems","volume":"282","author":"Rosi-Marshall","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0285","first-page":"85","article-title":"Evaluation of acute toxicity of triazophos and deltamethrin and their inhibitory effect on AChE activity in Channa punctatus","volume":"5","author":"Singh","year":"2018","journal-title":"Toxic. Rep."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0290","first-page":"9","article-title":"Evaluation of the effect of eggplant flour (Solanum melongena, L.) on rodents (Rattus norvergicus) on the levels of glucose, total cholesterol and triglycerides","volume":"16","author":"Soares","year":"2012","journal-title":"Essays Sci Bio Agrar. Health Sci."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0295","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/S0006-8993(00)03312-6","article-title":"Actions of cocaine-and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo\u2013pituitary axes in vitro and in vivo in male rats","volume":"893","author":"Stanley","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0300","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.aquatox.2013.12.010","article-title":"The apparently very variable potency of the anti-depressant fluoxetine","volume":"151","author":"Sumpter","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0305","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.fsi.2019.11.060","article-title":"Comparative transcriptome analysis of the gills of Procambarus clarkii provides novel insights into the immune-related mechanism of copper stress tolerance","volume":"96","author":"Tang","year":"2020","journal-title":"Fish & shellfish immun."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0310","first-page":"20201386","article-title":"Feeding, hunger, satiety and serotonin in invertebrates","volume":"287","author":"Tierney","year":"2020","journal-title":"Proc. R. Soc. Lond. B"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0315","series-title":"World Drug Report 2021","year":"2021"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0320","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1124\/jpet.105.091512","article-title":"The CART (cocaine-and amphetamine-regulated transcript) system in appetite and drug addiction","volume":"320","author":"Vicentic","year":"2007","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0325","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.ejphar.2005.11.041","article-title":"CART (cocaine-and amphetamine-regulated transcript) peptide receptors: specific binding in AtT20 cells","volume":"528","author":"Vicentic","year":"2005","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0330","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.neuropharm.2014.11.010","article-title":"Stereochemistry and neuropharmacology of a \u2018bath salt\u2019cathinone: S-enantiomer of mephedrone reduces cocaine-induced reward and withdrawal in invertebrates","volume":"91","author":"Vouga","year":"2015","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.scitotenv.2022.157025_bb0335","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.tree.2012.05.001","article-title":"Animal personalities: consequences for ecology and evolution","volume":"27","author":"Wolf","year":"2012","journal-title":"Trends Ecol. Evol."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0340","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.watres.2017.07.068","article-title":"Occurrence of illicit drugs in water and wastewater and their removal during wastewater treatment","volume":"124","author":"Yadav","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2022.157025_bb0345","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/npp.2009.149","article-title":"Fos after single and repeated self-administration of cocaine and saline in the rat: emphasis on the basal forebrain and recalibration of expression","volume":"35","author":"Zahm","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.scitotenv.2022.157025_bb3000","doi-asserted-by":"crossref","DOI":"10.1289\/ehp.11022","article-title":"Estimating community drug abuse by wastewater analysis","author":"Zuccato","year":"2008","journal-title":"Environ. Health Perspect."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969722041225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969722041225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T14:53:42Z","timestamp":1758725622000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969722041225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":72,"alternative-id":["S0048969722041225"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2022.157025","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential biochemical and behavioral responses induced by cocaine and benzoylecgonine exposure to the red swamp crayfish Procambarus clarkii","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2022.157025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"157025"}}