{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T07:37:32Z","timestamp":1772609852782,"version":"3.50.1"},"reference-count":87,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.scitotenv.2022.157922","type":"journal-article","created":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T11:09:04Z","timestamp":1660043344000},"page":"157922","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"P1","title":["Morphological and behavioral alterations in zebrafish larvae after exposure to contaminated river sediments collected in different weather conditions"],"prefix":"10.1016","volume":"851","author":[{"given":"Aliaksandra","family":"Shuliakevich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Nagengast","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melis","family":"Muz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Pipal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira","family":"Br\u00fcckner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klara","family":"Hilscherova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Werner","family":"Brack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Schiwy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henner","family":"Hollert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2022.157922_bb0005","series-title":"Ozonung von gereinigtem Abwasser: Schlussbericht Pilotversuch Regensdorf","author":"Abegglen","year":"2009"},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0015","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1039\/C9EM00463G","article-title":"Emerging investigator series: use of behavioural endpoints in the regulation of chemicals","volume":"22","author":"\u00c5gerstrand","year":"2020","journal-title":"Environ Sci Process Impacts"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0020","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.envint.2019.03.060","article-title":"Characterization of wastewater effluents in the Danube River basin with chemical screening, in vitro bioassays and antibiotic resistant genes analysis","volume":"127","author":"Alygizakis","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/372395","article-title":"Polycyclic aromatic hydrocarbons in urban stream sediments","volume":"2012","author":"Bathi","year":"2012","journal-title":"Adv. Civ. Eng."},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.cub.2021.11.038","article-title":"Micropollutants","volume":"32","author":"Bertram","year":"2022","journal-title":"Curr. Biol."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0035","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1111\/brv.12844","article-title":"Frontiers in quantifying wildlife behavioural responses to chemical pollution","volume":"97","author":"Bertram","year":"2022","journal-title":"Biol. Rev."},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0040","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S1383-5742(00)00004-1","article-title":"Effects of chemical contaminants on genetic diversity in natural populations: implications for biomonitoring and ecotoxicology","volume":"463","author":"Bickham","year":"2000","journal-title":"Mutat. Res. Rev. Mutat. Res."},{"issue":"8","key":"10.1016\/j.scitotenv.2022.157922_bb0045","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.envint.2010.06.011","article-title":"5th international PCB workshop\u2013summary and implications","volume":"36","author":"Birnbaum","year":"2010","journal-title":"Environ. Int."},{"issue":"11-12","key":"10.1016\/j.scitotenv.2022.157922_bb3500","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1177\/0748233719893198","article-title":"Inventory and evaluation of publicly available sources of information on hazards and risks of industrial chemicals","volume":"35","author":"Bond","year":"2019","journal-title":"Toxicol. Ind. Health"},{"issue":"1\u20132","key":"10.1016\/j.scitotenv.2022.157922_bb0050","doi-asserted-by":"crossref","first-page":"337","DOI":"10.2166\/wst.2017.548","article-title":"Status quo report on wastewater treatment plant, receiving water's biocoenosis and quality as basis for evaluation of large-scale ozonation process","volume":"77","author":"Br\u00fcckner","year":"2018","journal-title":"Water Sci. Technol. J. Int. Assoc. Water Pollut. Res."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0055","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ecoenv.2016.04.013","article-title":"The mode of bioturbation triggers pesticide remobilization from aquatic sediments","volume":"130","author":"Bundschuh","year":"2016","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0060","series-title":"European Overview - River Basin Management Plans: Accompanying the document 'Implementation of the Water Framework Directive (2000\/60\/EC) and the Floods Directive (2007\/60\/EC), Second River Basin Management Plans, First Flood Risk Management Plans'","first-page":"30","author":"Commission of the European Parliament","year":"2019"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0065","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1186\/s40064-016-1753-0","article-title":"Using genotoxic and haematological biomarkers as an evidence of environmental contamination in the Ocoa River native fish, Villavicencio-Meta, Colombia","volume":"5","author":"Corredor-Santamar\u00eda","year":"2016","journal-title":"SpringerPlus"},{"key":"10.1016\/j.scitotenv.2022.157922_bb3530","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126691","article-title":"Remobilization of pollutants during extreme flood events poses severe risks to human and environmental health","volume":"421","author":"Crawford","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0070","series-title":"Optimization of Accelerated Solvant Extraction (ASE) of Wide Range of Endocrine Disrupting Chemicals (EDC) in Sediment; 15-19 May","author":"Creusot","year":"2011"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0075","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.toxlet.2020.01.017","article-title":"Differences in biological activities between recombinant human paraoxonase 1 (rhPON1) subtype isozemys R\/Q as antidotes against organophosphorus poisonings","volume":"325","author":"Cui","year":"2020","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105913","article-title":"Mixture effects of oxygenated PAHs and benzoapyrene on cardiovascular development and function in zebrafish embryos","volume":"143","author":"Cunha","year":"2020","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0085","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/BF01055567","article-title":"Toxicity of mercury, copper, nickel, lead, and cobalt to embryos and larvae of zebrafish, Brachydanio rerio","volume":"21","author":"Dave","year":"1991","journal-title":"Arch. Environ. Contam. Toxicol."},{"issue":"1\u20132","key":"10.1016\/j.scitotenv.2022.157922_bb3505","first-page":"1","article-title":"Comparison of two extraction procedures for the assessment of sediment genotoxicity: implication of polar organic compounds","volume":"725","author":"Di Giorgio","year":"2011","journal-title":"Mutat. Res."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0095","series-title":"Wasserbeschaffenheit: Bestimmung der akuten Toxizit\u00e4t auf Zebrafisch-Eier (Danio rerio)","author":"DIN","year":"2009"},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0100","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/etc.13","article-title":"Distribution and toxicity of sediment-associated pesticides in urban and agricultural waterways from Illinois, USA","volume":"29","author":"Ding","year":"2010","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0105","series-title":"Heat Transfer in the Chemical, Food and Pharmaceutical Industries","article-title":"Freeze-drying","author":"Duroudier","year":"2016"},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0110","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0141-1136(00)00035-0","article-title":"Anthropogenic organic contaminants in the effluent of a combined sewer overflow: impact on Boston Harbor","volume":"51","author":"Eganhouse","year":"2001","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0115","author":"ELWAS-WEB"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0120","author":"ELWAS-WEB"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0125","series-title":"Karten. Wasserrahmenrichtlinie. Oberfl\u00e4chengew\u00e4sser. Bewertung","author":"ELWAS-WEB","year":"2021"},{"issue":"5","key":"10.1016\/j.scitotenv.2022.157922_bb0130","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1065\/espr2005.08.003","article-title":"The SeKT joint research project: definition of reference conditions, control sediments and toxicity thresholds for limnic sediment contact tests","volume":"12","author":"Feiler","year":"2005","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"9","key":"10.1016\/j.scitotenv.2022.157922_bb0140","doi-asserted-by":"crossref","first-page":"5620","DOI":"10.1021\/acs.est.0c06493","article-title":"The role of behavioral ecotoxicology in environmental protection","volume":"55","author":"Ford","year":"2021","journal-title":"Environ. Sci. Technol."},{"issue":"15","key":"10.1016\/j.scitotenv.2022.157922_bb0145","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1016\/S0883-2927(01)00063-4","article-title":"Historical record of polycyclic aromatic hydrocarbons (PAH) and heavy metals in floodplain sediments from the Rhine River (Hessisches ried, Germany)","volume":"16","author":"Gocht","year":"2001","journal-title":"Appl. Geochem."},{"issue":"9553","key":"10.1016\/j.scitotenv.2022.157922_bb0150","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1016\/S0140-6736(06)69665-7","article-title":"Developmental neurotoxicity of industrial chemicals","volume":"368","author":"Grandjean","year":"2006","journal-title":"Lancet"},{"issue":"7\u20139","key":"10.1016\/j.scitotenv.2022.157922_bb3510","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1080\/15287394.2011.550555","article-title":"Effects-directed analysis of sediments from polluted marine sites in Norway","volume":"74","author":"Grung","year":"2011","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.145702","article-title":"Shoaling, boldness, anxiety-like behavior and locomotion in zebrafish (Danio rerio) are altered by acute benzoapyrene exposure","volume":"774","author":"Hamilton","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"7","key":"10.1016\/j.scitotenv.2022.157922_bb0160","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1002\/cne.23240","article-title":"Phylogeny and expression divergence of metabotropic glutamate receptor genes in the brain of zebrafish (Danio rerio)","volume":"521","author":"Haug","year":"2013","journal-title":"J. Comp. Neurol."},{"issue":"5","key":"10.1016\/j.scitotenv.2022.157922_bb0165","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1289\/ehp.0901340","article-title":"Prenatal exposure to PBDEs and neurodevelopment","volume":"118","author":"Herbstman","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0170","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1023\/A:1020549103898","article-title":"Biological and chemical determination of dioxin-like compounds in sediments by means of a sediment triad approach in the catchment area of the river Neckar","volume":"11","author":"Hollert","year":"2002","journal-title":"Ecotoxicology"},{"issue":"197","key":"10.1016\/j.scitotenv.2022.157922_bb0175","article-title":"A new sediment contact assay to assess particle-bound pollutants using zebrafish (danio rerio) embryos","volume":"3","author":"Hollert","year":"2003","journal-title":"J. Soils Sediments"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.136174","article-title":"Differences in biomarker and behavioral responses to native and chemically dispersed crude and refined fossil oils in zebrafish early life stages","volume":"709","author":"Johann","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.110909","article-title":"Larval zebrafish as an in vitro model for evaluating toxicological effects of mycotoxins","volume":"202","author":"Juan-Garc\u00eda","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"12","key":"10.1016\/j.scitotenv.2022.157922_bb0200","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1002\/glia.23849","article-title":"Radial glia in the zebrafish brain: functional, structural, and physiological comparison with the mammalian glia","volume":"68","author":"Jurisch-Yaksi","year":"2020","journal-title":"Glia"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0205","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.scitotenv.2017.02.236","article-title":"In vivo EROD assays with the zebrafish (Danio rerio) as rapid screening tools for the detection of dioxin-like activity","volume":"590\u2013591","author":"Kais","year":"2017","journal-title":"Sci. Total Environ."},{"issue":"5","key":"10.1016\/j.scitotenv.2022.157922_bb0210","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1065\/espr2006.04.300","article-title":"Ecotoxicological assessment of sediment, suspended matter and water samples in the upper Danube River. A pilot study in search for the causes for the decline of fish catches (12 pp)","volume":"13","author":"Keiter","year":"2006","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"8","key":"10.1016\/j.scitotenv.2022.157922_bb0215","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1007\/s00216-007-1652-x","article-title":"Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river","volume":"390","author":"Keiter","year":"2008","journal-title":"Anal. Bioanal. Chem."},{"issue":"4","key":"10.1016\/j.scitotenv.2022.157922_bb0220","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1007\/s11368-010-0221-7","article-title":"DanTox\u2014a novel joint research project using zebrafish (Danio rerio) to identify specific toxicity and molecular modes of action of sediment-bound pollutants","volume":"10","author":"Keiter","year":"2010","journal-title":"J. Soils Sediments"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2019.105345","article-title":"Nitroaromatic compounds damage the DNA of zebrafish embryos (Danio rerio)","volume":"217","author":"Koske","year":"2019","journal-title":"Aquat. Toxicol."},{"issue":"8","key":"10.1016\/j.scitotenv.2022.157922_bb0235","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1897\/05-460R.1","article-title":"A novel contact assay for testing genotoxicity of chemicals and whole sediments in zebrafish embryos","volume":"25","author":"Kosmehl","year":"2006","journal-title":"Environ. Toxicol. Chem."},{"issue":"Pt A","key":"10.1016\/j.scitotenv.2022.157922_bb0240","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.jhazmat.2016.08.001","article-title":"Occurrence of UV filters, fragrances and organophosphate flame retardants in municipal WWTP effluents and their removal during membrane post-treatment","volume":"323","author":"Krzeminski","year":"2017","journal-title":"J. Hazard. Mater."},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0250","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s12302-018-0173-x","article-title":"An ecotoxicological view on neurotoxicity assessment","volume":"30","author":"Legradi","year":"2018","journal-title":"Environ. Sci. Eur."},{"key":"10.1016\/j.scitotenv.2022.157922_bb3515","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.envint.2012.01.010","article-title":"Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments","volume":"44","author":"L\u00fcbcke-von Varel","year":"2012","journal-title":"Environ. Int."},{"issue":"7","key":"10.1016\/j.scitotenv.2022.157922_bb0255","doi-asserted-by":"crossref","first-page":"5007","DOI":"10.1007\/s11356-013-2429-8","article-title":"Longer-term and short-term variability in pollution of fluvial sediments by dioxin-like and endocrine disruptive compounds","volume":"21","author":"Macikova","year":"2014","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0265","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.envres.2014.08.014","article-title":"Bioavailability, oxidative stress, neurotoxicity and genotoxicity of pharmaceuticals bound to marine sediments. The use of the polychaete Hediste diversicolor as bioindicator species","volume":"134","author":"Maranho","year":"2014","journal-title":"Environ. Res."},{"issue":"8","key":"10.1016\/j.scitotenv.2022.157922_bb0270","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.envint.2009.01.015","article-title":"Polychlorinated biphenyls in the surficial sediment of Indiana Harbor and Ship Canal, Lake Michigan","volume":"36","author":"Martinez","year":"2010","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb3520","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00216-017-0708-9","article-title":"A sediment extraction and cleanup method for wide-scope multitarget screening by liquid chromatography-high-resolution mass spectrometry","volume":"410","author":"Massei","year":"2018","journal-title":"Anal. Bioanal. Chem."},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0280","doi-asserted-by":"crossref","DOI":"10.1186\/s12302-019-0188-y","article-title":"Toxicity and neurotoxicity profiling of contaminated sediments from Gulf of Bothnia (Sweden): a multi-endpoint assay with zebrafish embryos","volume":"31","author":"Massei","year":"2019","journal-title":"Environ. Sci. Eur."},{"issue":"10","key":"10.1016\/j.scitotenv.2022.157922_bb0285","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1016\/j.chemosphere.2013.07.036","article-title":"The utility of behavioral studies for aquatic toxicology testing: a meta-analysis","volume":"93","author":"Melvin","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0290","series-title":"Study for the Strategy for a Non-toxic Environment of the 7th Environment Action Programme","author":"Milieu Ltd","year":"2017"},{"issue":"1","key":"10.1016\/j.scitotenv.2022.157922_bb0295","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1177\/0192623310385255","article-title":"Functional assays for neurotoxicity testing","volume":"39","author":"Moser","year":"2011","journal-title":"Toxicol. Pathol."},{"issue":"3","key":"10.1016\/j.scitotenv.2022.157922_bb3525","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1021\/acs.est.6b05468","article-title":"Mutagenicity in surface waters: synergistic effects of carboline alkaloids and aromatic amines","volume":"51","author":"Muz","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0305","series-title":"Test No. 236: Fish Embryo Acute Toxicity (FET) Test","author":"OECD","year":"2013"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.ntt.2020.106902","article-title":"Developmental exposure of zebrafish to vitamin D receptor acting drugs and environmental toxicants disrupts behavioral function","volume":"81","author":"Oliveri","year":"2020","journal-title":"Neurotoxicol. Teratol."},{"issue":"24","key":"10.1016\/j.scitotenv.2022.157922_bb0320","doi-asserted-by":"crossref","first-page":"13703","DOI":"10.1007\/s11356-014-3502-7","article-title":"Influence of sediment composition on PAH toxicity using zebrafish (Danio rerio) and Japanese medaka (Oryzias latipes) embryo-larval assays","volume":"21","author":"Perrichon","year":"2014","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125061","article-title":"Field cyanobacterial blooms producing retinoid compounds cause teratogenicity in zebrafish embryos","volume":"241","author":"Pipal","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2020.105613","article-title":"Neurobehavioral effects of cyanobacterial biomass field extracts on zebrafish embryos and potential role of retinoids","volume":"228","author":"P\u00edpal","year":"2020","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0335","series-title":"R: A Language and Environment for Statistical Computing","year":"2021"},{"issue":"28","key":"10.1016\/j.scitotenv.2022.157922_bb0340","doi-asserted-by":"crossref","first-page":"37534","DOI":"10.1007\/s11356-021-13370-2","article-title":"Synthetic organic chemicals (flame retardants and pesticides) with neurotoxic potential induced behavioral impairment on zebrafish (Danio rerio): a non-invasive approach for neurotoxicology","volume":"28","author":"Ren","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0350","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.envpol.2019.02.079","article-title":"Predicted sediment toxicity downstream of combined sewer overflows corresponds with effects measured in two sediment contact bioassays","volume":"248","author":"Schertzinger","year":"2019","journal-title":"Environ. Pollut."},{"issue":"21","key":"10.1016\/j.scitotenv.2022.157922_bb0355","doi-asserted-by":"crossref","first-page":"16305","DOI":"10.1007\/s11356-014-3185-0","article-title":"A novel contact assay for testing aryl hydrocarbon receptor (AhR)-mediated toxicity of chemicals and whole sediments in zebrafish (Danio rerio) embryos","volume":"22","author":"Schiwy","year":"2015","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116104","article-title":"Post-treatment of ozonated wastewater with activated carbon and biofiltration compared to membrane bioreactors: toxicity removal in vitro and in Potamopyrgus antipodarum","volume":"185","author":"Schneider","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0365","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.chemosphere.2014.02.064","article-title":"PAH toxicity at aqueous solubility in the fish embryo test with Danio rerio using passive dosing","volume":"112","author":"Seiler","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0375","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.117921","article-title":"Assessing the genotoxic potential of freshwater sediments after extensive rain events - lessons learned from a case study in an effluent-dominated river in Germany","volume":"209","author":"Shuliakevich","year":"2022","journal-title":"Water Res."},{"issue":"Pt 2","key":"10.1016\/j.scitotenv.2022.157922_bb0380","article-title":"Extensive rain events have a more substantial impact than advanced effluent treatment on the endocrine-disrupting activity in an effluent-dominated small river","volume":"807","author":"Shuliakevich","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"8","key":"10.1016\/j.scitotenv.2022.157922_bb0385","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.1016\/j.watres.2010.01.023","article-title":"Comparative toxicity assessment of ozone and activated carbon treated sewage effluents using an in vivo test battery","volume":"44","author":"Stalter","year":"2010","journal-title":"Water Res."},{"issue":"2","key":"10.1016\/j.scitotenv.2022.157922_bb0390","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.watres.2009.07.025","article-title":"Toxication or detoxication? In vivo toxicity assessment of ozonation as advanced wastewater treatment with the rainbow trout","volume":"44","author":"Stalter","year":"2010","journal-title":"Water Res."},{"issue":"6","key":"10.1016\/j.scitotenv.2022.157922_bb0395","first-page":"2341","article-title":"Mixture effects of drinking water disinfection by-products: implications for risk assessment","volume":"9","author":"Stalter","year":"2020","journal-title":"Environ. Sci.: Water Res. Technol."},{"issue":"2","key":"10.1016\/j.scitotenv.2022.157922_bb0400","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.reprotox.2011.06.121","article-title":"Zebrafish embryos as an alternative to animal experiments\u2013a commentary on the definition of the onset of protected life stages in animal welfare regulations","volume":"33","author":"Str\u00e4hle","year":"2012","journal-title":"Reprod. Toxicol."},{"issue":"10\u201312","key":"10.1016\/j.scitotenv.2022.157922_bb0405","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1163\/1568539X-00003020","article-title":"Zebrafish embryos and larvae in behavioural assays","volume":"149","author":"Tegelenbosch","year":"2012","journal-title":"Behav"},{"issue":"21","key":"10.1016\/j.scitotenv.2022.157922_bb0410","doi-asserted-by":"crossref","first-page":"16405","DOI":"10.1007\/s11356-014-3785-8","article-title":"Fish embryo tests with Danio rerio as a tool to evaluate surface water and sediment quality in rivers influenced by wastewater treatment plants using different treatment technologies","volume":"22","author":"Thellmann","year":"2015","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"4","key":"10.1016\/j.scitotenv.2022.157922_bb0415","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1023\/A:1016677629442","article-title":"Integration of genotoxic and population genetic endpoints in biomonitoring and risk assessment","volume":"10","author":"Theodorakis","year":"2001","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0420","series-title":"Weitergehende Abwasserreinigung: Ein wirksames und bezahlbares Instrument zur Verminderung von Spurenstoffen und Keimen im Wasserkreislauf: Gemeinsamer Schlussbericht der Projekte SchussenAktiv, SchussenAktivplus und SchussenAktivplus+","author":"Triebskorn","year":"2017"},{"issue":"4","key":"10.1016\/j.scitotenv.2022.157922_bb0425","doi-asserted-by":"crossref","first-page":"985","DOI":"10.2166\/wst.2010.004","article-title":"Efficiency, costs and benefits of AOPs for removal of pharmaceuticals from the water cycle","volume":"61","author":"Tuerk","year":"2010","journal-title":"Water Sci. Technol. J. Int. Assoc. Water Pollut. Res."},{"issue":"24","key":"10.1016\/j.scitotenv.2022.157922_bb0435","doi-asserted-by":"crossref","first-page":"13877","DOI":"10.1007\/s11356-014-2585-5","article-title":"Long-term disruption of growth, reproduction, and behavior after embryonic exposure of zebrafish to PAH-spiked sediment","volume":"21","author":"Vignet","year":"2014","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0450","author":"WetterKontor GmbH"},{"key":"10.1016\/j.scitotenv.2022.157922_bb0455","author":"WetterKontor GmbH"},{"issue":"2","key":"10.1016\/j.scitotenv.2022.157922_bb0460","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0304-3940(97)00488-6","article-title":"Serotonin as a regulator of hypothalamic-pituitary-interrenal activity in teleost fish","volume":"230","author":"Winberg","year":"1997","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0485","series-title":"7 Mechanisms of Hatching in Fish","first-page":"447","volume":"11","author":"Yamagami","year":"1988"},{"issue":"15","key":"10.1016\/j.scitotenv.2022.157922_bb0490","doi-asserted-by":"crossref","first-page":"5291","DOI":"10.1021\/es062917p","article-title":"Dioxin chronology and fluxes in sediments of the Houston Ship Channel, Texas: influences of non-steady-state sediment transport and total organic carbon","volume":"41","author":"Yeager","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2022.157922_bb0495","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125299","article-title":"Effect of suspended particles with different grain sizes on the bioaccumulation of PAHs by zebrafish (Danio rerio)","volume":"242","author":"Zhai","year":"2020","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.scitotenv.2022.157922_bb0500","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1007\/s11368-010-0317-0","article-title":"The impact of extraction methodologies on the toxicity of sediments in the zebrafish (Danio rerio) embryo test","volume":"11","author":"Zielke","year":"2011","journal-title":"J. Soils Sediments"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969722050215?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969722050215?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T14:56:57Z","timestamp":1758725817000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969722050215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":87,"alternative-id":["S0048969722050215"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2022.157922","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Morphological and behavioral alterations in zebrafish larvae after exposure to contaminated river sediments collected in different weather conditions","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2022.157922","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"157922"}}