{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:07:55Z","timestamp":1793725675297,"version":"4.6.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100004421","name":"World Bank Group","doi-asserted-by":"publisher","award":["NCSCM\/PUB\/2022\/0009"],"award-info":[{"award-number":["NCSCM\/PUB\/2022\/0009"]}],"id":[{"id":"10.13039\/100004421","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007907","name":"Ministry of Environment, Forest and Climate Change","doi-asserted-by":"publisher","award":["IR 12003"],"award-info":[{"award-number":["IR 12003"]}],"id":[{"id":"10.13039\/501100007907","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.scitotenv.2022.159221","type":"journal-article","created":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T01:51:44Z","timestamp":1664934704000},"page":"159221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"P1","title":["Networking and co-occurrence of virulent and multidrug resistant environmental bacteria in different aquatic systems: A gap in MDR-virulence transfer?"],"prefix":"10.1016","volume":"857","author":[{"given":"C.","family":"Saravanakumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.S.","family":"Neethu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Purvaja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Sunantha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.S.","family":"Robin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Ramesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.scitotenv.2022.159221_bb0005","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.MTBP-0013-2016","article-title":"Selection and transmission of antibiotic-resistant bacteria","volume":"5","author":"Andersson","year":"2017","journal-title":"Microbiol. Spectr."},{"issue":"5","key":"10.1016\/j.scitotenv.2022.159221_bb0010","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1099\/mic.0.033472-0","article-title":"The outer membrane protein OprQ and adherence of Pseudomonas aeruginosa to human fibronectin","volume":"156","author":"Arhin","year":"2010","journal-title":"Microbiology"},{"issue":"9","key":"10.1016\/j.scitotenv.2022.159221_bb0015","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1289\/ehp.1206316","article-title":"Human health risk assessment (HHRA) for environmental development and transfer of antibiotic resistance","volume":"121","author":"Ashbolt","year":"2013","journal-title":"Environ. Health Perspect."},{"issue":"W1","key":"10.1016\/j.scitotenv.2022.159221_bb0020","doi-asserted-by":"crossref","first-page":"W147","DOI":"10.1093\/nar\/gkw419","article-title":"Heatmapper: web-enabled heat mapping for all","volume":"44","author":"Babicki","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0025","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s12665-015-4990-6","article-title":"Seasonal variation in heavy metal contaminations in water and sediments of Jamshedpur stretch of Subarnarekha river, India","volume":"75","author":"Banerjee","year":"2016","journal-title":"Environ. Earth Sci."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0030","series-title":"Proceedings of the Int. AAAI Conf. Web Soc. Media, Palo Alto, CA","author":"Bastian","year":"2009"},{"key":"10.1016\/j.scitotenv.2022.159221_bb0035","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/ajcp\/45.4_ts.493","article-title":"Antibiotic susceptibility testing by a standardized single disk method","volume":"45","author":"Bauer","year":"1966","journal-title":"Am. J. Clin. Pathol."},{"issue":"2","key":"10.1016\/j.scitotenv.2022.159221_bb0040","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1128\/CMR.00059-12","article-title":"Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?","volume":"26","author":"Beceiro","year":"2013","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.115699","article-title":"Efficient detection and assessment of human exposure to trace antibiotic residues in drinking water","volume":"175","author":"Ben","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0050","doi-asserted-by":"crossref","first-page":"805","DOI":"10.3389\/fmicb.2019.00805","article-title":"Prevalence of antibiotic and heavy metal resistance determinants and virulence-related genetic elements in plasmids of Staphylococcus aureus","volume":"10","author":"Bukowski","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0055","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s150100070013","article-title":"Community-acquired acinetobacter meningitis in adults","volume":"28","author":"Chang","year":"2000","journal-title":"Infection"},{"key":"10.1016\/j.scitotenv.2022.159221_bb0060","first-page":"631","article-title":"BF in the 96-well microtiter plate","volume":"1149","author":"Coffey","year":"2014","journal-title":"Methods Protoc."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0070","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/798304","article-title":"Production and characterization of APfrom a high yielding and moderately halophilic strain of SD11 marine bacteria","author":"Cui","year":"2015","journal-title":"J. Chem."},{"issue":"5","key":"10.1016\/j.scitotenv.2022.159221_bb0075","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1093\/femsre\/fux023","article-title":"Evolution of bacterial virulence","volume":"41","author":"Diard","year":"2017","journal-title":"FEMS Microbiol. Rev."},{"issue":"3","key":"10.1016\/j.scitotenv.2022.159221_bb0080","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1128\/IAI.00850-10","article-title":"Full virulence of Pseudomonas aeruginosa requires OprF","volume":"79","author":"Fito-Boncompte","year":"2011","journal-title":"Infect. Immun."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0085","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1111\/j.1420-9101.2008.01598.x","article-title":"Host\u2013parasite coevolution and patterns of adaptation across time and space","volume":"21","author":"Gandon","year":"2008","journal-title":"J. Evol. Biol."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0090","series-title":"A Study On Indigenous Rice Varieties in Sundarban Delta and Their Role In Ensuring Local Food Security in the Face of Climate Change Threats","author":"Ghosh","year":"2017"},{"issue":"21","key":"10.1016\/j.scitotenv.2022.159221_bb0095","doi-asserted-by":"crossref","first-page":"7593","DOI":"10.1128\/AEM.00736-15","article-title":"The ocean as a global reservoir of antibiotic resistance genes","volume":"81","author":"Hatosy","year":"2015","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0100","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1038\/s41467-019-08853-3","article-title":"Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage","volume":"10","author":"Hendriksen","year":"2019","journal-title":"Nat. Commun."},{"issue":"2\u20133","key":"10.1016\/j.scitotenv.2022.159221_bb0105","first-page":"823","article-title":"Bioavailability of heavy metals monitoring water, sediments and fish species from a polluted estuary","volume":"162","author":"Juan","year":"2009","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.116818","article-title":"Antibiotic resistance gene load and irrigation intensity determine the impact of wastewater irrigation on antimicrobial resistance in the soil microbiome","volume":"193","author":"Kampouris","year":"2021","journal-title":"Water Res.","ISSN":"https:\/\/id.crossref.org\/issn\/0043-1354","issn-type":"print"},{"issue":"12","key":"10.1016\/j.scitotenv.2022.159221_bb0115","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1111\/j.1469-0691.2010.03177.x","article-title":"Analysis of quorum sensing-dependent virulence factor production and its relationship with antimicrobial susceptibility in Pseudomonas aeruginosa respiratory isolates","volume":"16","author":"Karatuna","year":"2010","journal-title":"Clin. Microbiol. Infect."},{"issue":"24","key":"10.1016\/j.scitotenv.2022.159221_bb0120","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.tim.2016.02.001","article-title":"Involvement of bacteria other than Clostridium difficile in antibiotic-associated diarrhoea","volume":"6","author":"Larcombe","year":"2016","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0125","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ddtec.2014.02.001","article-title":"General principles of antibiotic resistance in bacteria","volume":"11","author":"Martinez","year":"2014","journal-title":"Drug Discov. Today Technol."},{"issue":"2","key":"10.1016\/j.scitotenv.2022.159221_bb0130","doi-asserted-by":"crossref","first-page":"432","DOI":"10.2134\/jeq2015.06.0317","article-title":"Culture-based methods for detection of antibiotic resistance in agroecosystems: advantages, challenges, and gaps in knowledge","volume":"45","author":"McLain","year":"2016","journal-title":"J. Environ. Qual."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0135","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s10529-008-9833-z","article-title":"Novel extracellular PL C purified from a marine bacterium, Pseudoalteromonas sp. J937","volume":"31","author":"Mo","year":"2009","journal-title":"Biotechnol. Lett."},{"issue":"4","key":"10.1016\/j.scitotenv.2022.159221_bb0140","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.polar.2015.10.002","article-title":"Relatively high antibiotic resistance among heterotrophic bacteria from arctic fjord sediments than water \u2013 evidence towards better selection pressure in the fjord sediments","volume":"9","author":"Mohamed Hatha","year":"2015","journal-title":"Polar Sci."},{"issue":"6","key":"10.1016\/j.scitotenv.2022.159221_bb0145","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1139\/cjm-2014-0803","article-title":"Heavy-metal resistance in gram-negative bacteria isolated from Kongsfjord, Arctic","volume":"61","author":"Neethu","year":"2015","journal-title":"Can. J. Microbiol."},{"issue":"3","key":"10.1016\/j.scitotenv.2022.159221_bb0150","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s11783-019-1121-8","article-title":"Culturomics and metagenomics: in understanding of environmental resistome","volume":"13","author":"Nowrotek","year":"2019","journal-title":"Front. Environ. Sci. Eng."},{"issue":"11","key":"10.1016\/j.scitotenv.2022.159221_bb0155","first-page":"10115","article-title":"Brackish water aquaculture development and its impacts on agriculture land: a case study on coastal blocks of Purba Medinipur District, West Bengal, India using multi-temporal satellite data and GIS techniques","volume":"13","author":"Ojha","year":"2018","journal-title":"Int. J. Appl. Eng. Res."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0160","series-title":"Tackling drug-resistant infections globally: final report and recommendations","author":"O'Neill","year":"2016"},{"issue":"9","key":"10.1016\/j.scitotenv.2022.159221_bb0165","doi-asserted-by":"crossref","first-page":"4987","DOI":"10.1128\/IAI.70.9.4987-4996.2002","article-title":"Virulent combinations of adhesin and toxin genes in natural populations of Staphylococcus aureus","volume":"70","author":"Peacock","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0170","doi-asserted-by":"crossref","first-page":"2928","DOI":"10.3389\/fmicb.2018.02928","article-title":"Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens","volume":"9","author":"Peterson","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0175","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/apm.12553","article-title":"Heavy metal resistance and virulence profile in Pseudomonas aeruginosa isolated from Brazilian soils","volume":"124","author":"Pitondo-Silva","year":"2016","journal-title":"APMIS"},{"key":"10.1016\/j.scitotenv.2022.159221_bb0180","doi-asserted-by":"crossref","first-page":"3523","DOI":"10.1128\/AAC.49.8.3523-3525.2005","article-title":"Origin of plasmid-mediated quinolone resistance determinant QnrA","volume":"49","author":"Poirel","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0185","first-page":"211","article-title":"Genomic science in understanding cholera outbreaks and evolution of Vibrio cholerae as a human pathogen","volume":"379","author":"Robins","year":"2014","journal-title":"Curr. Top. Microbiol. Immunol."},{"issue":"14","key":"10.1016\/j.scitotenv.2022.159221_bb0190","doi-asserted-by":"crossref","first-page":"4908","DOI":"10.1128\/JB.187.14.4908-4920.2005","article-title":"A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance","volume":"87","author":"Salunkhe","year":"2005","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0195","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s12665-017-6451-x","article-title":"Heavy metals in the Ganga (Hooghly) River estuary sediment column: evaluation of association, geochemical cycling and anthropogenic enrichment","volume":"76","author":"Samanta","year":"2017","journal-title":"Environ. Earth Sci."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0200","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jgar.2018.07.004","article-title":"Pseudomonas fluorescens tolerance to benzyldimethyldodecyl ammonium chloride: altered phenotype and cross-resistance","volume":"15","author":"Sousa-Silva","year":"2018","journal-title":"J. Glob. Antimicrob. Resist."},{"issue":"1","key":"10.1016\/j.scitotenv.2022.159221_bb0205","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.mib.2010.10.003","article-title":"Mechanisms controlling pathogen colonization of the gut","volume":"14","author":"Stecher","year":"2011","journal-title":"Curr. Opin. Microbiol."},{"issue":"1621","key":"10.1016\/j.scitotenv.2022.159221_bb0210","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1098\/rspb.2007.0245","article-title":"Grazing protozoa and the evolution of the Escherichia coli O157:H7 Shiga toxin-encoding prophage","volume":"274","author":"Steinberg","year":"2007","journal-title":"Proc. R. Soc. B."},{"issue":"3","key":"10.1016\/j.scitotenv.2022.159221_bb0215","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nrmicro2298","article-title":"The population genetics of commensal Escherichia coli","volume":"8","author":"Tenaillon","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"issue":"10","key":"10.1016\/j.scitotenv.2022.159221_bb0220","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1128\/JCM.40.10.3613-3619.2002","article-title":"Detection in Escherichia coli of the genes encoding the major virulence factors, the genes defining the O157:H7 serotype, and components of the type 2 Shiga toxin family by multiplex PCR","volume":"40","author":"Wang","year":"2002","journal-title":"J. Clin. Microbiol."},{"issue":"2","key":"10.1016\/j.scitotenv.2022.159221_bb0225","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1128\/jb.173.2.697-703.1991","article-title":"16S ribosomal DNA amplification for phylogenetic study","volume":"173","author":"Weisburg","year":"1991","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.scitotenv.2022.159221_bb0230","series-title":"Global Action Plan","year":"2016"},{"key":"10.1016\/j.scitotenv.2022.159221_bb0235","series-title":"Antimicrobial resistance","year":"2020"},{"key":"10.1016\/j.scitotenv.2022.159221_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.141948","article-title":"Microplastics in freshwater sediment: a review on methods, occurrence, and sources","volume":"754","author":"Yang","year":"2021","journal-title":"Sci. Total Environ."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969722063203?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969722063203?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T15:14:22Z","timestamp":1758726862000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969722063203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":47,"alternative-id":["S0048969722063203"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2022.159221","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Networking and co-occurrence of virulent and multidrug resistant environmental bacteria in different aquatic systems: A gap in MDR-virulence transfer?","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2022.159221","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"159221"}}