{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T04:08:45Z","timestamp":1793678925407,"version":"4.5.1"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010009","name":"Heilongjiang Provincial Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["LBH-Z21073"],"award-info":[{"award-number":["LBH-Z21073"]}],"id":[{"id":"10.13039\/501100010009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2021M701021"],"award-info":[{"award-number":["2021M701021"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.scitotenv.2023.162101","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T02:15:30Z","timestamp":1675822530000},"page":"162101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Dysregulation of the microbiota-brain axis during long-term exposure to polystyrene nanoplastics in rats and the protective role of dihydrocaffeic acid"],"prefix":"10.1016","volume":"874","author":[{"given":"Wenbo","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanyu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiming","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwei","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengru","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changhao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianshu","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2023.162101_bb0005","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1136\/gutjnl-2020-323071","article-title":"Gut microbiota-derived metabolites as central regulators in metabolic disorders","volume":"70","author":"Agus","year":"2021","journal-title":"Gut"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0010","doi-asserted-by":"crossref","first-page":"37678","DOI":"10.1074\/jbc.M703416200","article-title":"Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase a in parotid acinar cells","volume":"282","author":"Baggaley","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"Pt 2","key":"10.1016\/j.scitotenv.2023.162101_bb0015","article-title":"Micro- and nanoplastic induced cellular toxicity in mammals: a review","volume":"755","author":"Banerjee","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0020","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1093\/advances\/nmaa016","article-title":"The role of the gut microbiota in dietary interventions for depression and anxiety","volume":"11","author":"Bear","year":"2020","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.113433","article-title":"Nanoplastics are bioaccumulated in fish liver and muscle and cause DNA damage after a chronic exposure","volume":"212","author":"Brandts","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0030","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.neuro.2013.11.003","article-title":"Downregulation of PMCA2 increases the vulnerability of midbrain neurons to mitochondrial complex I inhibition","volume":"40","author":"Brendel","year":"2014","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0035","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1113\/EP087404","article-title":"Gut microbiota diversity is associated with cardiorespiratory fitness in post-primary treatment breast cancer survivors","volume":"104","author":"Carter","year":"2019","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2020.112895","article-title":"Heat stress induced oxidative damage and perturbation in BDNF\/ERK1\/2\/CREB axis in hippocampus impairs spatial memory","volume":"396","author":"Chauhan","year":"2021","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0045","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1001\/archsurg.1970.01340280030009","article-title":"Intestinal mucosal lesion in low-flow states. I. A morphological, hemo -dynamic, and metabolic reappraisal","volume":"101","author":"Chiu","year":"1970","journal-title":"Arch. Surg."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0050","first-page":"11","article-title":"Probiotics, prebiotics and postbiotics on mitigation of depression symptoms: modulation of the brain-gut-microbiome axis","author":"Chudzik","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0055","first-page":"12","article-title":"Microbiota-orientated treatments for major depression and schizophrenia","author":"Fond","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.138792","article-title":"Nano-plastics and their analytical characterisation and fate in the marine environment: from source to sea","volume":"732","author":"Gangadoo","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0065","first-page":"26","article-title":"Caffeic and dihydrocaffeic acids promote longevity and increase stress resistance in Caenorhabditis elegans by modulating expression of stress-related genes","author":"Gutierrez-Zetina","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0070","doi-asserted-by":"crossref","first-page":"12300","DOI":"10.1021\/acs.est.9b02540","article-title":"Plastic teabags release billions of microparticles and nanoparticles into tea","volume":"53","author":"Hernandez","year":"2019","journal-title":"Environ.Sci.Technol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0075","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s12989-020-00387-7","article-title":"Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature","volume":"17","author":"Hirt","year":"2020","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0080","first-page":"23","article-title":"Size-dependent effects of polystyrene nanoparticles (PS-NPs) on behaviors and endogenous neurochemicals in zebrafish larvae","author":"Hwang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0085","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3109\/10253890.2014.910650","article-title":"Social defeat stress induces a depression-like phenotype in adolescent male c57BL\/6 mice","volume":"17","author":"I\u00f1iguez","year":"2014","journal-title":"Stress"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0090","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.neuroimage.2015.11.018","article-title":"Magnetic resonance spectroscopy reveals oral lactobacillus promotion of increases in brain GABA,N-acetyl aspartate and glutamate","volume":"125","author":"Janik","year":"2016","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.scitotenv.2023.162101_bb0095","first-page":"137","article-title":"Cryptdin-2 predicts intestinal injury during heatstroke in mice","volume":"41","author":"Ji","year":"2018","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0100","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1039\/C7MB00246G","article-title":"DBA-induced caspase-3-dependent apoptosis occurs through mitochondrial translocation of cyt-c in the rat hippocampus","volume":"13","author":"Jiang","year":"2017","journal-title":"Mol. BioSyst."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0105","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12199-020-00870-9","article-title":"Health impacts of environmental contamination of micro- and nanoplastics: a review","volume":"25","author":"Jiang","year":"2020","journal-title":"Environ. Health Prev. Med."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0110","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/978-1-4939-8994-2_4","article-title":"The elevated plus maze test for measuring anxiety-like behavior in rodents","volume":"1916","author":"Kraeuter","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.134267","article-title":"Micro(nano)plastics pollution and human health: how plastics can induce carcinogenesis to humans?","volume":"298","author":"Kumar","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0120","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neures.2017.04.012","article-title":"Early deprivation increases high-leaning behavior, a novel anxiety-like behavior, in the open field test in rats","volume":"123","author":"Kuniishi","year":"2017","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0125","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.chemosphere.2015.11.078","article-title":"Characterisation of nanoplastics during the degradation of polystyrene","volume":"145","author":"Lambert","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0130","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.phymed.2013.06.002","article-title":"Cerebral metabonomics study on Parkinson's disease mice treated with extract of Acanthopanax senticosus harms","volume":"20","author":"Li","year":"2013","journal-title":"Phytomedicine"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0135","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12989-021-00414-1","article-title":"Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis","volume":"18","author":"Liang","year":"2021","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.150027","article-title":"Polystyrene nanoplastics exacerbated the ecotoxicological and potential carcinogenic effects of tetracycline in juvenile grass carp (Ctenopharyngodon idella)","volume":"803","author":"Liu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0145","doi-asserted-by":"crossref","first-page":"8228","DOI":"10.1128\/AEM.71.12.8228-8235.2005","article-title":"UniFrac: a new phylogenetic method for comparing microbial communities","volume":"71","author":"Lozupone","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0150","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.neuron.2021.11.025","article-title":"Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca(2+) homeostasis and network synchrony via PMCA2\/ATP2B2","volume":"110","author":"Mart\u00edn-de-Saavedra","year":"2022","journal-title":"Neuron"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0155","doi-asserted-by":"crossref","first-page":"3919","DOI":"10.1021\/acs.jafc.9b00522","article-title":"Antiproliferative activity and cell metabolism of hydroxycinnamic acids in human colon adenocarcinoma cell lines","volume":"67","author":"Martini","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.132631","article-title":"Effects of nano- and microplastics on kidney: physicochemical properties, bioaccumulation, oxidative stress and immunoreaction","volume":"288","author":"Meng","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0165","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1186\/s12974-019-1585-2","article-title":"Pathological pain processing in mouse models of multiple sclerosis and spinal cord injury: contribution of plasma membrane calcium ATPase 2 (PMCA2)","volume":"16","author":"Mirabelli","year":"2019","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0170","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/s41579-020-00460-0","article-title":"The gut microbiota-brain axis in behaviour and brain disorders","volume":"19","author":"Morais","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0175","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/2419096","article-title":"Dihydrocaffeic acid prevents UVB-induced oxidative stress leading to the inhibition of apoptosis and MMP-1 expression via p38 signaling pathway","volume":"2019","author":"Oliveira","year":"2019","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"4","key":"10.1016\/j.scitotenv.2023.162101_bb0180","doi-asserted-by":"crossref","first-page":"208","DOI":"10.3109\/08941931003623622","article-title":"Quantification of ischemia-reperfusion injury to the small intestine using a macroscopic score","volume":"23","author":"Petrat","year":"2010","journal-title":"J.Investig.Surg."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0185","doi-asserted-by":"crossref","first-page":"8806","DOI":"10.1039\/D1NR00038A","article-title":"Perturbation of gut microbiota plays an important role in micro\/nanoplastics-induced gut barrier dysfunction","volume":"13","author":"Qiao","year":"2021","journal-title":"Nanoscale"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0190","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1007\/s11910-017-0802-6","article-title":"Microbiota-brain-gut axis and neurodegenerative diseases","volume":"17","author":"Quigley","year":"2017","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0195","doi-asserted-by":"crossref","first-page":"G263","DOI":"10.1152\/ajpgi.00275.2018","article-title":"Cyclic AMP-dependent protein kinase a and EPAC mediate VIP and secretin stimulation of PAK4 and activation of Na(+), K(+)-ATPase in pancreatic acinar cells","volume":"316","author":"Ramos-Alvarez","year":"2019","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0200","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.bbi.2019.03.006","article-title":"Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner","volume":"80","author":"Rincel","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0205","first-page":"10","article-title":"Scientific evidence about the risks of micro and nanoplastics (MNPLs) to human health and their exposure routes through the environment","author":"Rodrigues","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0210","first-page":"11","article-title":"Understanding emotions: origins and roles of the amygdala","author":"\u0160imi\u0107","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0215","doi-asserted-by":"crossref","first-page":"3085181","DOI":"10.1155\/2019\/3085181","article-title":"Dangerous liaison: Helicobacter pylori, ganglionitis, and myenteric gastric neurons: a histopathological study","volume":"2019","author":"Sticlaru","year":"2019","journal-title":"Anal. Cell. Pathol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2020.105021","article-title":"Uptake and cellular effects of PE, PP, PET and PVC microplastic particles","volume":"70","author":"Stock","year":"2021","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0225","doi-asserted-by":"crossref","DOI":"10.1021\/acsnano.2c01872","article-title":"Polystyrene nanoplastics toxicity to zebrafish: dysregulation of the brain-intestine-microbiota axis","author":"Teng","year":"2022","journal-title":"ACS Nano"},{"key":"10.1016\/j.scitotenv.2023.162101_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107340","article-title":"Experimental evidence that polystyrene nanoplastics cross the intestinal barrier of European seabass","volume":"166","author":"Vagner","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0235","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.1801","article-title":"Fetal exposure to dichloroacetic acid and impaired cognitive function in the adulthood","volume":"10","author":"Wang","year":"2020","journal-title":"Brain Behav."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0240","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1007\/s00128-021-03348-8","article-title":"Nanoplastics induce more serious microbiota dysbiosis and inflammation in the gut of adult zebrafish than microplastics","volume":"107","author":"Xie","year":"2021","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126092","article-title":"Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco-2 cells","volume":"417","author":"Xu","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0250","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jss.2020.11.041","article-title":"Dexmedetomidine resists intestinal ischemia-reperfusion injury by inhibiting TLR4\/MyD88\/NF-\u03baB signaling","volume":"260","author":"Yang","year":"2021","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.156917","article-title":"Combined effects of micro-\/nano-plastics and oxytetracycline on the intestinal histopathology and microbiome in zebrafish (Danio rerio)","volume":"843","author":"Yu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.162101_bb0260","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.cmet.2020.11.017","article-title":"Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism","volume":"33","author":"Zheng","year":"2021","journal-title":"Cell Metab."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723007179?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723007179?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T15:03:35Z","timestamp":1793631815000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969723007179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":52,"alternative-id":["S0048969723007179"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.162101","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dysregulation of the microbiota-brain axis during long-term exposure to polystyrene nanoplastics in rats and the protective role of dihydrocaffeic acid","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.162101","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"162101"}}