{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:46:58Z","timestamp":1790624818447,"version":"4.1.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31372497"],"award-info":[{"award-number":["31372497"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31672623"],"award-info":[{"award-number":["31672623"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.scitotenv.2023.163616","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T16:27:35Z","timestamp":1682008055000},"page":"163616","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Interleukin-17A knockout or self-recovery alleviated autoimmune reaction induced by fluoride in mouse testis"],"prefix":"10.1016","volume":"884","author":[{"given":"Panhong","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaidong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zilong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangfei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram Kumar","family":"Manthari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jundong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinling","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2023.163616_bb0005","doi-asserted-by":"crossref","first-page":"540","DOI":"10.4049\/jimmunol.1400931","article-title":"IL-17 promotes murine lupus","volume":"193","author":"Amarilyo","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0010","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.jclepro.2019.04.325","article-title":"Efficient phosphate removal from water for controlling eutrophication using novel composite adsorbent","volume":"228","author":"Awual","year":"2019","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0015","doi-asserted-by":"crossref","first-page":"5541","DOI":"10.1016\/j.watres.2012.07.038","article-title":"Efficient arsenic(V) removal from water by ligand exchange fibrous adsorbent","volume":"46","author":"Awual","year":"2012","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0020","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.cej.2019.01.125","article-title":"Assessment of enhanced nitrite removal and monitoring using ligand modified stable conjugate materials","volume":"363","author":"Awual","year":"2019","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0025","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.compositesb.2019.05.078","article-title":"Cleaning the arsenic(V) contaminated water for safe-guarding the public health using novel composite material","volume":"171","author":"Awual","year":"2019","journal-title":"Compos. Part B-Eng."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0030","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.jclepro.2019.04.280","article-title":"Introducing an amine functionalized novel conjugate material for toxic nitrite detection and adsorption from wastewater","volume":"228","author":"Awual","year":"2019","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0035","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1080\/10643380701413310","article-title":"A conceptual overview on sustainable technologies for the defluoridation of drinking water","volume":"38","author":"Ayoob","year":"2008","journal-title":"Crit. Rev. Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0040","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.3390\/nu12072074","article-title":"Relevance of essential trace elements in nutrition and drinking water for human health and autoimmune disease risk","volume":"12","author":"Cannas","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0045","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s12011-019-01994-y","article-title":"A comparative analysis of fluoride-contaminated groundwater and sodium fluoride-induced reproductive toxicity and its reversibility in male rats","volume":"197","author":"Chaithra","year":"2020","journal-title":"Biol. Trace. Elem. Res."},{"key":"10.1016\/j.scitotenv.2023.163616_bb3525","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.semcdb.2016.01.019","article-title":"Testicular immunoregulation and spermatogenesis","volume":"59","author":"Chen","year":"2016","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0050","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s12011-018-1458-z","article-title":"Sodium fluoride (NaF) induces inflammatory responses via activating MAPKs\/NF-kappaB signaling pathway and reducing anti-inflammatory cytokine expression in the mouse liver","volume":"189","author":"Chen","year":"2019","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0055","doi-asserted-by":"crossref","first-page":"e94","DOI":"10.1016\/S2542-5196(20)30060-7","article-title":"Fluorosis: an ongoing challenge for India","volume":"4","author":"Del-Bello","year":"2020","journal-title":"Lancet. Planet. Health."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0060","first-page":"543","article-title":"IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients","volume":"116","author":"Dong","year":"2003","journal-title":"Chin. Med. J-Peking"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0065","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/7403796","article-title":"Regulation of inflammation in autoimmune disease","volume":"2019","author":"Duan","year":"2019","journal-title":"J Immunol Res"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0070","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1177\/00220345950740011201","article-title":"Effect of aging on animal response to chronic fluoride exposure","volume":"74","author":"Dunipace","year":"1995","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0075","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/s41573-020-0081-9","article-title":"Targeting co-stimulatory molecules in autoimmune disease","volume":"19","author":"Edner","year":"2020","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0080","doi-asserted-by":"crossref","first-page":"330","DOI":"10.18632\/aging.100459","article-title":"Role of apoptosis in disease","volume":"4","author":"Favaloro","year":"2012","journal-title":"Aging-Us"},{"key":"10.1016\/j.scitotenv.2023.163616_bb3515","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s11157-017-9449-7","article-title":"Desalination and water reuse to address global water scarcity","volume":"16","author":"Gude","year":"2017","journal-title":"Rev. Environ. Sci. Bio-technol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0085","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1177\/0748233708089041","article-title":"The toxic effects of sodium fluoride on the reproductive system of male rats","volume":"23","author":"Gupta","year":"2007","journal-title":"Toxicol. Ind. Health"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0090","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.envpol.2019.06.107","article-title":"Fluoride-induced unrestored arrest during haploid period of spermatogenesis via the regulation of DDX25 in rats","volume":"253","author":"Han","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0095","doi-asserted-by":"crossref","first-page":"4678","DOI":"10.1021\/acs.chemrev.0c01263","article-title":"Chemical aspects of human and environmental overload with fluorine","volume":"121","author":"Han","year":"2021","journal-title":"Chem. Rev."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0100","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.chemosphere.2018.08.009","article-title":"Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1\u03b1","volume":"211","author":"He","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0105","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s12403-020-00347-8","article-title":"Groundwater arsenic and fluoride and associated arsenicosis and fluorosis in China: occurrence, distribution and management","volume":"12","author":"He","year":"2020","journal-title":"Expos. Health"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0110","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1038\/s41423-022-00874-1","article-title":"The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription","volume":"19","author":"Hisada","year":"2022","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0115","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1038\/s41577-021-00598-9","article-title":"FOXP3 as a master regulator of treg cells","volume":"21","author":"Hori","year":"2021","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0120","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1749-6632.2010.05825.x","article-title":"The IL-17 pathway as a major therapeutic target in autoimmune diseases","volume":"1217","author":"Hu","year":"2011","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0125","doi-asserted-by":"crossref","first-page":"32173","DOI":"10.1038\/srep32173","article-title":"Role of IL-17 pathways in immune privilege: a RNA deep sequencing analysis of the mice testis exposure to fluoride","volume":"6","author":"Huo","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0130","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1600-065X.2008.00699.x","article-title":"The roles of IL-17A in inflammatory immune responses and host defense against pathogens","volume":"226","author":"Iwakura","year":"2008","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0135","doi-asserted-by":"crossref","DOI":"10.1111\/and.13092","article-title":"The role of regulatory T cells in autoimmune orchitis","volume":"50","author":"Jacobo","year":"2018","journal-title":"Andrologia"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0140","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12916-020-1503-6","article-title":"Remission of autoimmune diabetes by anti-TCR combination therapies with anti-IL-17A or\/and anti-IL-6 in the IDDM rat model of type 1 diabetes","volume":"18","author":"Jorns","year":"2020","journal-title":"BMC Med."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0145","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1080\/10643389.2019.1647028","article-title":"Fluoride and human health: systematic appraisal of sources, exposures, metabolism, and toxicity","volume":"50","author":"Kabir","year":"2019","journal-title":"Crit. Rev. Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0150","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.molliq.2019.04.060","article-title":"Efficient toxic nitrite monitoring and removal from aqueous media with ligand based conjugate materials","volume":"285","author":"Kamel","year":"2019","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0155","doi-asserted-by":"crossref","first-page":"824","DOI":"10.2164\/jandrol.111.015529","article-title":"Involvement of Fas\/Fas-L and Bax\/Bcl-2 systems in germ cell death following immunization with syngeneic testicular germ cells in mice","volume":"33","author":"Kuerban","year":"2012","journal-title":"J. Androl."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0160","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/humupd\/dmac035","article-title":"Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries","volume":"29","author":"Levine","year":"2023","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.140533","article-title":"Self-recovery study of the adverse effects of fluoride on small intestine: involvement of pyroptosis induced inflammation","volume":"742","author":"Li","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128178","article-title":"Interleukin 17A deficiency alleviates fluoride-induced testicular injury by inhibiting the immune response and apoptosis","volume":"263","author":"Li","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0175","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.chemosphere.2018.04.144","article-title":"Mus musculus bone fluoride concentration as a useful biomarker for risk assessment of skeletal fluorosis in volcanic areas","volume":"205","author":"Linhares","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112506","article-title":"Co-exposure to fluoride and arsenic disrupts intestinal flora balance and induces testicular autophagy in offspring rats","volume":"222","author":"Liu","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jhazmat.2012.12.043","article-title":"Defluoridation of drinking water using adsorption processes","volume":"248\u2013249","author":"Loganathan","year":"2013","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0190","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1262\/jrd.2012-121","article-title":"The effects of adjuvants on autoimmune responses against testicular antigens in mice","volume":"59","author":"Musha","year":"2013","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0195","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s00795-011-0539-2","article-title":"Postinflammation stage of autoimmune orchitis induced by immunization with syngeneic testicular germ cells alone in mice","volume":"45","author":"Naito","year":"2012","journal-title":"Med. Mol. Morphol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0200","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1080\/15548627.2020.1810920","article-title":"IRGM links autoimmunity to autophagy","volume":"17","author":"Nath","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0205","doi-asserted-by":"crossref","first-page":"42391","DOI":"10.1038\/srep42391","article-title":"Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice","volume":"7","author":"Nicolas","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0210","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/andr.12954","article-title":"Sperm immunization and rat spermatogenesis: dysfunctional blood-testis barrier and perturbed sertoli cell cytoskeleton","volume":"9","author":"Noguchi","year":"2020","journal-title":"Andrology"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0220","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.tox.2018.05.012","article-title":"Fluoride induced tissue hypercalcemia, IL-17 mediated inflammation and apoptosis lead to cardiomyopathy: ultrastructural and biochemical findings","volume":"406","author":"Quadri","year":"2018","journal-title":"Toxicology"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0225","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.1074\/mcp.M115.052951","article-title":"Autoimmune regulator (AIRE) is expressed in spermatogenic cells, and it altered the expression of several nucleic-acid-binding and cytoskeletal proteins in germ cell 1 spermatogonial (GC1-spg) cells","volume":"15","author":"Radhakrishnan","year":"2016","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0230","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.cej.2017.08.037","article-title":"Novel nano-conjugate materials for effective arsenic(V) and phosphate capturing in aqueous media","volume":"331","author":"Shahat","year":"2018","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0235","first-page":"907","article-title":"Potential ameliorative effect of artemisia absinthium supplement against sodium fluoride-induced prostatic toxicity in rats","volume":"77","author":"Shakir-Saleh","year":"2022","journal-title":"Arch. Razi Inst."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0240","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3390\/ijms21010055","article-title":"DNA damage response and oxidative stress in systemic autoimmunity","volume":"21","author":"Souliotis","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0245","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s40572-020-00270-9","article-title":"Fluoride in drinking water and skeletal fluorosis: a review of the global impact","volume":"7","author":"Srivastava","year":"2020","journal-title":"Curr. Environ. Health Rep."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0250","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/cei.12287","article-title":"Endogenous interleukin (IL)-17A promotes pristane-induced systemic autoimmunity and lupus nephritis induced by pristane","volume":"176","author":"Summers","year":"2014","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0255","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.chemosphere.2015.09.061","article-title":"Fluoride decreased the sperm ATP of mice through inhabiting mitochondrial respiration","volume":"144","author":"Sun","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0260","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1007\/s12011-017-1181-1","article-title":"Effects of fluoride on SOD and CAT in testis and epididymis of mice","volume":"184","author":"Sun","year":"2018","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0265","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s00204-017-2054-2","article-title":"Alterations in epididymal proteomics and antioxidant activity of mice exposed to fluoride","volume":"92","author":"Sun","year":"2018","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0270","first-page":"573","article-title":"Early diagnosis and complete recovery from fluorosis through practice of interventions","volume":"62","author":"Susheela","year":"2014","journal-title":"JAPI"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0275","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s00005-015-0344-z","article-title":"The role of IL-17 and Th17 lymphocytes in autoimmune diseases","volume":"63","author":"Tabarkiewicz","year":"2015","journal-title":"Arch. Immunol. Ther. Exp."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0280","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1172\/JCI89927","article-title":"Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance","volume":"127","author":"Tung","year":"2017","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0285","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1016\/j.ajpath.2021.05.021","article-title":"Multiple lesions contribute to infertility in males lacking autoimmune regulator","volume":"191","author":"Warren","year":"2021","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0290","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.chemosphere.2016.03.045","article-title":"Chronic fluoride exposure-induced testicular toxicity is associated with inflammatory response in mice","volume":"153","author":"Wei","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0295","series-title":"Guidelines for Drinking-Water Quality","author":"WHO","year":"2011"},{"key":"10.1016\/j.scitotenv.2023.163616_bb0300","doi-asserted-by":"crossref","first-page":"292","DOI":"10.3389\/fimmu.2017.00292","article-title":"Major histocompatibility complex (MHC) class I and MHC class II proteins: conformational plasticity in antigen presentation","volume":"8","author":"Wieczorek","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0305","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201745553","article-title":"Chemical and genetic control of IFNgamma-induced MHCII expression","volume":"19","author":"Wijdeven","year":"2018","journal-title":"EMBO Rep."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0310","doi-asserted-by":"crossref","first-page":"13333","DOI":"10.1021\/acs.jafc.9b05789","article-title":"Fluoride induces autoimmune orchitis involved with enhanced IL-17A secretion in mice testis","volume":"67","author":"Wu","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0315","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.taap.2013.04.033","article-title":"Fluoride-elicited developmental testicular toxicity in rats: roles of endoplasmic reticulum stress and inflammatory response","volume":"271","author":"Zhang","year":"2013","journal-title":"Toxicol. Appl. Pharm."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0320","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.fct.2016.05.017","article-title":"Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice","volume":"94","author":"Zhang","year":"2016","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0325","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.taap.2016.09.018","article-title":"Choline supplementation alleviates fluoride-induced testicular toxicity by restoring the NGF and MEK expression in mice","volume":"310","author":"Zhang","year":"2016","journal-title":"Toxicol. Appl. Pharm."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0330","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.envpol.2016.01.059","article-title":"Excessive apoptosis and defective autophagy contribute to developmental testicular toxicity induced by fluoride","volume":"212","author":"Zhang","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0335","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1007\/s00204-018-2305-x","article-title":"Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes","volume":"92","author":"Zhao","year":"2018","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0340","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.150184","article-title":"Fluoride exposure induces mitochondrial damage and mitophagy via activation of the IL-17A pathway in hepatocytes","volume":"804","author":"Zhao","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0345","doi-asserted-by":"crossref","first-page":"11350","DOI":"10.1038\/ncomms11350","article-title":"Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator","volume":"7","author":"Zhu","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.scitotenv.2023.163616_bb0350","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.641164","article-title":"The role of AIRE deficiency in infertility and its potential pathogenesis","volume":"12","author":"Zou","year":"2021","journal-title":"Front. Immunol."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723022350?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723022350?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T16:18:13Z","timestamp":1785255493000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969723022350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":71,"alternative-id":["S0048969723022350"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.163616","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interleukin-17A knockout or self-recovery alleviated autoimmune reaction induced by fluoride in mouse testis","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.163616","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"163616"}}