{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:45:28Z","timestamp":1793148328719,"version":"4.5.0"},"reference-count":87,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31972754"],"award-info":[{"award-number":["31972754"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.scitotenv.2023.164172","type":"journal-article","created":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T03:47:25Z","timestamp":1684208845000},"page":"164172","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"special_numbering":"C","title":["Chronic arsenic exposure induces ferroptosis via enhancing ferritinophagy in chicken livers"],"prefix":"10.1016","volume":"890","author":[{"given":"Lu","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanjun","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijie","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biqi","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2023.164172_bb0005","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.tips.2017.02.005","article-title":"Ferroptosis inhibition: mechanisms and opportunities","volume":"38","author":"Angeli","year":"2017","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0010","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.3390\/molecules27072129","article-title":"Ferroptosis: a new road towards cancer management","volume":"27","author":"Bano","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0015","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1038\/s41418-020-00685-9","article-title":"Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer\u2019s disease","volume":"28","author":"Bao","year":"2021","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0020","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1089\/ars.2014.6166","article-title":"Role of 4-hydroxynonenal-protein adducts in human diseases","volume":"22","author":"Barrera","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0025","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1146\/annurev-pharmtox-030220-013418","article-title":"Arsenic: a global environmental challenge","volume":"61","author":"Chen","year":"2021","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0030","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1146\/annurev-pharmtox-010818-021031","article-title":"Metals and mechanisms of carcinogenesis","volume":"59","author":"Chen","year":"2019","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0035","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.scitotenv.2019.01.361","article-title":"The toxic potentials and focus of disinfection byproducts based on the human embryonic kidney (HEK293) cell model","volume":"664","author":"Chen","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0040","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1146\/annurev-arplant-043015-112301","article-title":"Toxic heavy metal and metalloid accumulation in crop plants and foods","volume":"67","author":"Clemens","year":"2016","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0045","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1080\/15287394.2017.1376405","article-title":"Arsenic trioxide exposure impairs testicular morphology in adult male mice and consequent fetus viability","volume":"80","author":"da Silva","year":"2017","journal-title":"J. Toxicol. Environ. Health A."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0050","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0055","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1161\/CIRCRESAHA.120.316509","article-title":"Loss of cardiac ferritin H facilitates cardiomyopathy via slc7a11-mediated ferroptosis","volume":"127","author":"Fang","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0060","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/s41573-021-00233-1","article-title":"Targeting oxidative stress in disease: promise and limitations of antioxidant therapy","volume":"20","author":"Forman","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0065","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1038\/ncb3064","article-title":"Inactivation of the ferroptosis regulator GPX4 triggers acute renal failure in mice","volume":"16","author":"Friedmann Angeli","year":"2014","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0070","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/cr.2016.95","article-title":"Ferroptosis is an autophagic cell death process","volume":"26","author":"Gao","year":"2016","journal-title":"Cell Res."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0075","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.envint.2019.02.058","article-title":"Pathways of arsenic uptake and efflux","volume":"126","author":"Garbinski","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2023.164172_bb5000","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130082","article-title":"Effects of thiacloprid exposure on microbiota-gut-liver axis: multiomics mechanistic analysis in Japanese quails","volume":"442","author":"Han","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.164172_bb5005","doi-asserted-by":"crossref","first-page":"5555","DOI":"10.1039\/C9FO01152H","article-title":"Dietary melatonin attenuates chromium-induced lung injury via activating the Sirt1\/Pgc-1\u03b1\/Nrf2 pathway","volume":"10","author":"Han","year":"2019","journal-title":"Food Funct."},{"key":"10.1016\/j.scitotenv.2023.164172_bb5010","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113870","article-title":"Deltamethrin induces liver fibrosis in quails via activation of the TGF-\u03b21\/Smad signaling pathway","volume":"259","author":"Han","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125984","article-title":"Pulmonary inflammatory and fibrogenic response induced by graphitized multi-walled carbon nanotube involved in cGAS-STING signaling pathway","volume":"417","author":"Han","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0085","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1007\/s12011-021-02766-3","article-title":"Harmful effects of inorganic mercury exposure on kidney cells: mitochondrial dynamics disorder and excessive oxidative stress","volume":"200","author":"Han","year":"2021","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0090","doi-asserted-by":"crossref","DOI":"10.1289\/EHP1878","article-title":"Effects of orally ingested arsenic on respiratory epithelial permeability to bacteria and small molecules in mice","volume":"125","author":"Henderson","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0095","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nrm.2017.95","article-title":"AMPK: Guardian of metabolism and mitochondrial homeostasis","volume":"19","author":"Herzig","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0100","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1080\/15548627.2016.1187366","article-title":"Autophagy promotes ferroptosis by degradation of ferritin","volume":"12","author":"Hou","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0105","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1093\/toxsci\/kfr184","article-title":"Arsenic exposure and toxicology: a historical perspective","volume":"123","author":"Hughes","year":"2011","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0110","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3390\/nu9070671","article-title":"Antioxidants mediate both iron homeostasis and oxidative stress","volume":"9","author":"Imam","year":"2017","journal-title":"Nutrients"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0115","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/nm.2613","article-title":"Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export","volume":"18","author":"Lei","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117319","article-title":"Toxicological effects of deltamethrin on quail cerebrum: weakened antioxidant defense and enhanced apoptosis","volume":"286","author":"Li","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0125","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1007\/s12035-022-02744-3","article-title":"Activation of the GPX4\/TLR4 signaling pathway participates in the alleviation of selenium yeast on deltamethrin-provoked cerebrum injury in quails","volume":"59","author":"Li","year":"2022","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0130","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.freeradbiomed.2020.08.009","article-title":"Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury","volume":"160","author":"Li","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0135","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.chemosphere.2019.06.096","article-title":"Exploring the kidney hazard of exposure to mercuric chloride in mice: disorder of mitochondrial dynamics induces oxidative stress and results in apoptosis","volume":"234","author":"Li","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111501","article-title":"Exploring the liver fibrosis induced by deltamethrin exposure in quails and elucidating the protective mechanism of resveratrol","volume":"207","author":"Li","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0145","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1002\/tox.23548","article-title":"Deltamethrin induces apoptosis in cerebrum neurons of quail via promoting endoplasmic reticulum stress and mitochondrial dysfunction","volume":"37","author":"Li","year":"2022","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0150","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12943-020-1138-4","article-title":"Autophagy and autophagy-related proteins in cancer","volume":"19","author":"Li","year":"2020","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124337","article-title":"Land-use change caused by anthropogenic activities increase fluoride and arsenic pollution in groundwater and human health risk","volume":"406","author":"Li","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0160","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1093\/humrep\/deaa363","article-title":"Erastin induces ferroptosis via ferroportin-mediated iron accumulation in endometriosis","volume":"36","author":"Li","year":"2021","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0165","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/s41589-018-0072-x","article-title":"Scavenging of superoxide by a membrane-bound superoxide oxidase","volume":"14","author":"Lundgren","year":"2018","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113812","article-title":"Sulforaphane prevents chromium-induced lung injury in rats via activation of the Akt\/GSK-3\u03b2\/Fyn pathway","volume":"259","author":"Lv","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135915","article-title":"Imidacloprid-induced liver fibrosis in quails via activation of the TGF-\u03b21\/Smad pathway","volume":"705","author":"Lv","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0180","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/nature13148","article-title":"Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy","volume":"509","author":"Mancias","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0185","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0039-9140(02)00268-0","article-title":"Arsenic round the world: a review","volume":"58","author":"Mandal","year":"2002","journal-title":"Talanta."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0190","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.redox.2017.08.015","article-title":"Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis","volume":"14","author":"Masaldan","year":"2018","journal-title":"Redox Biol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0195","doi-asserted-by":"crossref","first-page":"93","DOI":"10.17843\/rpmesp.2018.351.3604","article-title":"Arsenic intake: impact in human nutrition and health","volume":"35","author":"Medina-Pizzali","year":"2018","journal-title":"Rev. Peru. Med. Exp. Salud Publica"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101328","article-title":"Insight into the mechanism of ferroptosis inhibition by ferrostatin-1","volume":"28","author":"Miotto","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0205","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.cell.2011.10.026","article-title":"Autophagy: renovation of cells and tissues","volume":"147","author":"Mizushima","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0210","doi-asserted-by":"crossref","first-page":"619","DOI":"10.4315\/0362-028X.JFP-17-086","article-title":"Antibiotic residues in chicken meat: global prevalence, threats, and decontamination strategies: a Rreview","volume":"81","author":"Muaz","year":"2018","journal-title":"J. Food Prot."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0215","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.cell.2016.12.034","article-title":"A red carpet for iron metabolism","volume":"168","author":"Muckenthaler","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.yrtph.2019.104539","article-title":"Arsenic exposure: a public health problem leading to several cancers","volume":"110","author":"Palma-Lara","year":"2020","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0225","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1126\/science.aba1510","article-title":"Global threat of arsenic in groundwater","volume":"368","author":"Podgorski","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0230","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1002\/hep.31328","article-title":"Iron chaperone poly rC binding protein 1 protects mouse liver from lipid peroxidation and steatosis","volume":"73","author":"Protchenko","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0235","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1091\/mbc.e10-06-0551","article-title":"Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo","volume":"22","author":"Qi","year":"2011","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2021.100973","article-title":"Autophagy in liver diseases: a review","volume":"82","author":"Qian","year":"2021","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0245","doi-asserted-by":"crossref","first-page":"4266","DOI":"10.1080\/15548627.2021.1911016","article-title":"Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells","volume":"17","author":"Qin","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111872","article-title":"Ferritinophagy and ferroptosis in cardiovascular disease: mechanisms and potential applications","volume":"141","author":"Qin","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0255","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.cell.2012.05.009","article-title":"Ironing out cell death mechanisms","volume":"149","author":"Reed","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118438","article-title":"An appraisal on molecular and biochemical signalling cascades during arsenic-induced hepatotoxicity","volume":"260","author":"Renu","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0265","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.cell.2017.02.004","article-title":"mTOR signaling in growth, metabolism, and disease","volume":"168","author":"Saxton","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0270","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.2174\/1389557522666220218123404","article-title":"Ferroptosis inhibitors as potential new therapeutic targets for cardiovascular disease","volume":"22","author":"Shaghaghi","year":"2022","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0275","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12610-021-00125-9","article-title":"Is ferroptosis involved in ROS-induced testicular lesions in a varicocele rat model?","volume":"31","author":"Shaygannia","year":"2021","journal-title":"Basic Clin. Androl."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0280","article-title":"Emerging strategies of cancer therapy based on ferroptosis","volume":"30","author":"Shen","year":"2018","journal-title":"Adv. Mater."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0285","doi-asserted-by":"crossref","first-page":"814","DOI":"10.3390\/genes10100814","article-title":"Genomics of avian viral infections","volume":"10","author":"Smith","year":"2019","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0290","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.tcb.2020.02.009","article-title":"Emerging mechanisms and disease relevance of ferroptosis","volume":"30","author":"Stockwell","year":"2020","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0295","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.envres.2005.07.009","article-title":"After the Aznalc\u00f3llar mine spill: arsenic, zinc, selenium, lead and copper levels in the livers and bones of five waterfowl species","volume":"100","author":"Taggart","year":"2006","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0300","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.freeradbiomed.2019.01.052","article-title":"Ferritinophagy activation and sideroflexin1-dependent mitochondria iron overload is involved in apelin-13-induced cardiomyocytes hypertrophy","volume":"134","author":"Tang","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0305","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuro.2018.04.012","article-title":"Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure","volume":"67","author":"Tang","year":"2018","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0310","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.124959","article-title":"Autophagic-CTSB-inflammasome axis modulates hepatic stellate cells activation in arsenic-induced liver fibrosis","volume":"242","author":"Tao","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0315","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev.bi.56.070187.001445","article-title":"Ferritin: structure, gene regulation, and cellular function in animals, plants, and microorganisms","volume":"56","author":"Theil","year":"1987","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0320","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.freeradbiomed.2020.02.027","article-title":"Lipid peroxidation and ferroptosis: the role of GSH and GPX4","volume":"152","author":"Ursini","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0325","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ejphar.2019.01.043","article-title":"Betaine modulates oxidative stress, inflammation, apoptosis, autophagy, and Akt\/mTOR signaling in methionine-choline deficiency-induced fatty liver disease","volume":"848","author":"Veskovic","year":"2019","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0330","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.envres.2014.08.034","article-title":"Association of inorganic arsenic exposure with liver cancer mortality: a meta-analysis","volume":"135","author":"Wang","year":"2014","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0335","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.121390","article-title":"Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway","volume":"384","author":"Wei","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0340","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.cmet.2015.06.006","article-title":"Redox homeostasis and mitochondrial dynamics","volume":"22","author":"Willems","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130276","article-title":"The lncRNA HOTAIR via miR-17-5p is involved in arsenite-induced hepatic fibrosis through regulation of Th17 cell differentiation","volume":"443","author":"Wu","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112114","article-title":"Arsenite induces ferroptosis in the neuronal cells via activation of ferritinophagy","volume":"151","author":"Xiao","year":"2021","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0355","doi-asserted-by":"crossref","unstructured":"Xiao, T., Zou, Z., Xue, J., Syed, BM., Sun, J., Dai, X., Shi, M., Li, J., Wei, S., Tang, H., Zhang, A., Liu, Q., 2021b. LncRNA H19-mediated M2 polarization of macrophages promotes myofibroblast differentiation in pulmonary fibrosis induced by arsenic exposure. Environ. Pollut. 268, 115810. doi:https:\/\/doi.org\/10.1016\/j.envpol.2020.115810.","DOI":"10.1016\/j.envpol.2020.115810"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0360","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10571-022-01196-6","article-title":"Role of ferroptosis in stroke","volume":"43","author":"Xu","year":"2023","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0365","doi-asserted-by":"crossref","first-page":"37157","DOI":"10.1038\/srep37157","article-title":"Regulation of Sirt1\/Nrf2\/TNF-\u03b1 signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity","volume":"6","author":"Yang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0375","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jare.2021.04.002","article-title":"The link between deacetylation and hepatotoxicity induced by exposure to hexavalent chromium","volume":"35","author":"Yang","year":"2022","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114855","article-title":"Hexavalent chromium induces mitochondrial dynamics disorder in rat liver by inhibiting AMPK\/PGC-1\u03b1 signaling pathway","volume":"265","author":"Yang","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0380","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.cell.2013.12.010","article-title":"Regulation of ferroptotic cancer cell death by GPX4","volume":"156","author":"Yang","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.scitotenv.2023.164172_bb0385","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1038\/s41467-019-10991-7","article-title":"Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis","volume":"10","author":"Yoshida","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0390","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1038\/nrn1537","article-title":"Iron, brain ageing and neurodegenerative disorders","volume":"5","author":"Zecca","year":"2004","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0395","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1007\/s12035-020-02277-7","article-title":"New insights into the role of ferritin in iron homeostasis and neurodegenerative diseases","volume":"58","author":"Zhang","year":"2021","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0400","doi-asserted-by":"crossref","first-page":"9252","DOI":"10.1039\/D0FO01223H","article-title":"Inflammation response after the cessation of chronic arsenic exposure and post-treatment of natural astaxanthin in liver: potential role of cytokine-mediated cell-cell interactions","volume":"11","author":"Zhang","year":"2020","journal-title":"Food Funct."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0405","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112320","article-title":"Selenium mitigated aflatoxin B1-induced cardiotoxicity with potential regulation of 4 selenoproteins and ferroptosis signaling in chicks","volume":"154","author":"Zhao","year":"2021","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0410","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111061","article-title":"Hexavalent chromium induces renal apoptosis and autophagy via disordering the balance of mitochondrial dynamics in rats","volume":"204","author":"Zheng","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0415","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.semcancer.2019.03.002","article-title":"Ferroptosis is a type of autophagy-dependent cell death","volume":"266","author":"Zhou","year":"2020","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.scitotenv.2023.164172_bb0420","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1080\/15548627.2021.1984656","article-title":"Full-coverage regulations of autophagy by ROS: from induction to maturation","volume":"18","author":"Zhou","year":"2022","journal-title":"Autophagy"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723027936?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723027936?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T15:54:16Z","timestamp":1758729256000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969723027936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":87,"alternative-id":["S0048969723027936"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.164172","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic arsenic exposure induces ferroptosis via enhancing ferritinophagy in chicken livers","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.164172","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"164172"}}