{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:29:21Z","timestamp":1792103361695,"version":"4.4.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["41661144033"],"award-info":[{"award-number":["41661144033"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42207437"],"award-info":[{"award-number":["42207437"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["71961137007"],"award-info":[{"award-number":["71961137007"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.scitotenv.2023.165029","type":"journal-article","created":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T21:30:36Z","timestamp":1687383036000},"page":"165029","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Spectrum of pharmaceutical residues in commercial manure-based organic fertilizers from multi-provinces of China mainland in relation to animal farming and possible environmental risks of fertilization"],"prefix":"10.1016","volume":"894","author":[{"given":"Bing","family":"Hong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shen","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2023.165029_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109565","article-title":"Adsorption-desorption of doxycycline in agricultural soils: batch and stirred-flow-chamber experiments","volume":"186","author":"\u00c1lvarez-Esmor\u00eds","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0010","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1002\/jssc.201700883","article-title":"Analysis of emerging organic contaminants in poultry manure by gas chromatography-tandem mass spectrometry","volume":"41","author":"Aznar","year":"2017","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0015","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.envint.2015.10.015","article-title":"Concentrations of antibiotics predicted to select for resistant bacteria: proposed limits for environmental regulation","volume":"86","author":"Bengtsson-Palme","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0020","doi-asserted-by":"crossref","first-page":"5444","DOI":"10.1016\/j.biortech.2008.11.027","article-title":"Composting of animal manures and chemical criteria for compost maturity assessment. A review","volume":"100","author":"Bernal","year":"2009","journal-title":"Bioresource Technol."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0025","author":"European Commission","year":"2003"},{"key":"10.1016\/j.scitotenv.2023.165029_bb0030","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.jhazmat.2018.07.092","article-title":"Human and veterinary antibiotics during composting of sludge or manure: global perspectives on persistence, degradation, and resistance genes","volume":"359","author":"Ezzariai","year":"2018","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2021.125069","article-title":"A review targeting veterinary antibiotics removal from livestock manure management systems and future outlook","volume":"333","author":"Gaballah","year":"2021","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0040","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.scitotenv.2018.11.061","article-title":"Veterinary pharmaceuticals and antibiotics in manure and slurry and their fate in amended agricultural soils: findings from an experimental field site (Baix Empord\u00e0, NE Catalonia)","volume":"654","author":"Gros","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0045","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.biortech.2012.12.194","article-title":"Degradation of veterinary antibiotics and hormone during broiler manure composting","volume":"131","author":"Ho","year":"2013","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.121594","article-title":"Spectrum and environmental risks of residual pharmaceuticals in stream water with emphasis on its relation to epidemic infectious disease and anthropogenic activity in watershed","volume":"385","author":"Hong","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.152979","article-title":"Sedimentary spectrum and potential ecological risks of residual pharmaceuticals in relation to sediment-water partitioning and land uses in a watershed","volume":"817","author":"Hong","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0060","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1080\/10643389.2020.1753634","article-title":"Pharmaceutical and personal care products (PPCPs) in the environment: plant uptake, translocation, bioaccumulation, and human health risks","volume":"51","author":"Keerthanan","year":"2020","journal-title":"Crit. Rev. Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0065","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3390\/toxics10050213","article-title":"Bioaccumulation and mass balance analysis of veterinary antibiotics in an agricultural environment","volume":"10","author":"Kim","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.scitotenv.2023.165029_bb0070","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.wasman.2011.07.026","article-title":"Decline in extractable antibiotics in manure-based composts during composting","volume":"32","author":"Kim","year":"2012","journal-title":"Waste Manag."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2113(05)87001-4","article-title":"Antibiotic use in agriculture and their impact on the terrestrial environment","volume":"87","author":"Kumar","year":"2005","journal-title":"Adv. Agron."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0080","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1080\/10934529.2019.1655368","article-title":"The xenobiotic doxycycline affects nitrogen transformations in soil and impacts earthworms and cultivated plants","volume":"54","author":"Litskas","year":"2019","journal-title":"J. Environ. Sci. Health. Part A"},{"key":"10.1016\/j.scitotenv.2023.165029_bb0085","first-page":"640","article-title":"Nutrient and heavy metal contents in organic fertilizers produced in Fujian. Fujian","volume":"35","author":"Liu","year":"2020","journal-title":"J. Agri. Sci."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0090","unstructured":"MA (Ministry of Agriculture of the People's Republic of China), 2005. Announcement No. 560 for the banning list of veterinary pharmaceuticals. http:\/\/www.moa.gov.cn\/nybgb\/2005\/dsyq\/201806\/t20180618_6152552.htm (accessed 11 April 2023)."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0095","unstructured":"MA (Ministry of Agriculture of the People's Republic of China), 2015. Announcement No. 2292 for banning fluoroquinolones uses in animal farming\/meat productions. http:\/\/www.moa.gov.cn\/gk\/tzgg_1\/gg\/201509\/t20150907_4819267.htm (accessed 11 April 2023)."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0100","unstructured":"MARA (Ministry of Agriculture and Rural Affairs of the People's Republic of China), 2019. Report on the use of veterinary antibiotics of China by 2018. Official Veterinary Bulletin 21, 57\u201359. http:\/\/www.moa.gov.cn\/gk\/sygb\/201911\/P020191108590803635472.pdf (accessed 11 April 2023)."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0105","unstructured":"MARA (Ministry of Agriculture and Rural Affairs of the People's Republic of China), 2020. Annual report on the use of veterinary antibiotics in China by 2019. Official Veterinary Bulletin 22, 31\u201334. http:\/\/www.moa.gov.cn\/gk\/sygb\/202012\/P020201214509059672681.pdf (accessed 11 April 2023)."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0110","unstructured":"MARA (Ministry of Agriculture and Rural Affairs of the People's Republic of China), 2021. Annual report on the use of veterinary antibiotics in China by 2020. Official Veterinary Bulletin 23, 33\u201336. http:\/\/www.moa.gov.cn\/gk\/sygb\/202111\/P020211104353940540082.pdf (accessed 11 April 2023)."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0115","series-title":"Announcement No. 573 for Revision on the List of Animal Epidemic Diseases","author":"MARA","year":"2022"},{"key":"10.1016\/j.scitotenv.2023.165029_bb0120","article-title":"Antimicrobial resistance: a one health perspective","volume":"6","author":"McEwen","year":"2017","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0125","doi-asserted-by":"crossref","first-page":"S93","DOI":"10.1086\/340246","article-title":"Antimicrobial use and resistance in animals","volume":"34","author":"McEwen","year":"2002","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0130","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.chemosphere.2011.03.048","article-title":"Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level","volume":"84","author":"Motoyama","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.165029_bb0135","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1021\/jf960215l","article-title":"Binding of fluoroquinolone carboxylic acid derivatives to clay minerals","volume":"45","author":"Nowara","year":"1997","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0140","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.scitotenv.2016.03.123","article-title":"Occurrence of trace elements and antibiotics in manure-based fertilizers from the Zhejiang Province of China","volume":"559","author":"Qian","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0145","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S0045-6535(99)00442-7","article-title":"Sorption and mobility of metronidazole, olaquindox, oxytetracycline and tylosin in soil","volume":"40","author":"Rab\u00f8lle","year":"2000","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.165029_bb0150","unstructured":"Rashidi, H., 2016. Breeding against Infectious Diseases in Animals. Wageningen University, Wageningen, Netherlands. http:\/\/edepot.wur.nl\/373810 (accessed 11 April 2023)."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0155","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.biortech.2011.12.073","article-title":"Composting of swine manure spiked with sulfadiazine, chlortetracycline and ciprofloxacin","volume":"126","author":"Selvam","year":"2012","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149205","article-title":"A systematic review on antibiotics misuse in livestock and aquaculture and regulation implications in China","volume":"798","author":"Shao","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0165","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.1073\/pnas.1503141112","article-title":"Global trends in antimicrobial use in food animals","volume":"112","author":"Van Boeckel","year":"2015","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.150086","article-title":"Response of antibiotic resistance to the co-exposure of sulfamethoxazole and copper during swine manure composting","volume":"805","author":"Wu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0175","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.envpol.2016.10.044","article-title":"Changes in antibiotic concentrations and antibiotic resistome during commercial composting of animal manures","volume":"219","author":"Xie","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0180","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/j.scitotenv.2018.09.147","article-title":"Fate of veterinary antibiotics during animal manure composting","volume":"650","author":"Zhang","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105458","article-title":"Variation of antibiotic resistome during commercial livestock manure composting","volume":"136","author":"Zhang","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0190","doi-asserted-by":"crossref","first-page":"6772","DOI":"10.1021\/acs.est.5b00729","article-title":"Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling, and linkage to bacterial resistance","volume":"49","author":"Zhang","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2022.115320","article-title":"Environmental risks caused by livestock and poultry farms to the soils: comparison of swine, chicken, and cattle farms","volume":"317","author":"Zhang","year":"2022","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0200","doi-asserted-by":"crossref","first-page":"5827","DOI":"10.1007\/s11356-014-2493-8","article-title":"Sorption-desorption and transport of trimethoprim and sulfonamide antibiotics in agricultural soil: effect of soil type, dissolved organic matter, and pH","volume":"21","author":"Zhang","year":"2014","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0205","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.scitotenv.2009.11.014","article-title":"Residues of veterinary antibiotics in manures from feedlot livestock in eight provinces of China","volume":"408","author":"Zhao","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.153356","article-title":"Fingerprinting pharmaceuticals of multiple sources at a provincial watershed scale","volume":"820","author":"Zhou","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.164046","article-title":"Co-proliferation of antimicrobial resistance genes in tilapia farming ponds associated with use of antimicrobials","volume":"887","author":"Zhou","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.165029_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127006","article-title":"Antibiotics in animal manure and manure-based fertilizers: occurrence and ecological risk assessment","volume":"255","author":"Zhou","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.165029_bb0225","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1073\/pnas.1222743110","article-title":"Diverse and abundant antibiotic resistance genes in Chinese swine farms","volume":"110","author":"Zhu","year":"2013","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723036525?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723036525?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T20:43:43Z","timestamp":1786913023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969723036525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":45,"alternative-id":["S0048969723036525"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.165029","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spectrum of pharmaceutical residues in commercial manure-based organic fertilizers from multi-provinces of China mainland in relation to animal farming and possible environmental risks of fertilization","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.165029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"165029"}}