{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:36:44Z","timestamp":1787841404211,"version":"build-2784847793"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42107290"],"award-info":[{"award-number":["42107290"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2021NTST24"],"award-info":[{"award-number":["2021NTST24"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.scitotenv.2023.167057","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T21:02:33Z","timestamp":1694552553000},"page":"167057","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Synergistic\/antagonistic toxicity characterization and source-apportionment of heavy metals and organophosphorus pesticides by the biospectroscopy-bioreporter-coupling approach"],"prefix":"10.1016","volume":"905","author":[{"given":"Qiuyuan","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanghe","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naifu","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dayi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2023.167057_bb0005","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1080\/02772248.2015.1092541","article-title":"Bacterial degradation of monocrotophos and phyto- and cyto-toxicological evaluation of metabolites","volume":"97","author":"Abraham","year":"2015","journal-title":"Toxicol. Environ. Chem."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0010","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3390\/toxics9030042","article-title":"Heavy metals and pesticides toxicity in agricultural soil and plants: ecological risks and human health implications","volume":"9","author":"Alengebawy","year":"2021","journal-title":"Toxics"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0015","first-page":"603","article-title":"Cytotoxicity assessment of monocrotophos in Paramecium caudatum and Oxytricha fallax","volume":"31","author":"Amanchi","year":"2010","journal-title":"J. Environ. Biol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0020","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1080\/15287394.2015.1079582","article-title":"Oxidative stress, cytotoxicity, and genotoxicity induced by methyl parathion in human gingival fibroblasts: protective role of epigallocatechin-3-gallate","volume":"78","author":"Argentin","year":"2015","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0025","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1038\/nprot.2014.110","article-title":"Using Fourier transform IR spectroscopy to analyze biological materials","volume":"9","author":"Baker","year":"2014","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0030","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1152\/physrev.00044.2005","article-title":"The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology","volume":"87","author":"Bedard","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0035","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S1369-5274(03)00059-6","article-title":"Microbial whole-cell sensing systems of environmental pollutants","volume":"6","author":"Belkin","year":"2003","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0040","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.biopha.2016.04.063","article-title":"Crocin, the main active saffron constituent, mitigates dichlorvos-induced oxidative stress and apoptosis in HCT-116 cells","volume":"82","author":"Ben Salem","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0045","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0300-483X(80)90097-9","article-title":"Mechanisms of chromium toxicity in mammalian cell cultures","volume":"17","author":"Bianchi","year":"1980","journal-title":"Toxicology"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0050","series-title":"EUR 27968 EN","article-title":"Review of case studies on the human and environmental risk assessment of chemical mixtures","author":"Bopp","year":"2016"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0055","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0925-4005(96)01906-5","article-title":"Whole cell biosensors","volume":"34","author":"Bousse","year":"1996","journal-title":"Sensors Actuators B Chem."},{"issue":"10","key":"10.1016\/j.scitotenv.2023.167057_bb0060","doi-asserted-by":"crossref","first-page":"4059","DOI":"10.1039\/C5AY00377F","article-title":"Application of vibrational spectroscopy techniques to non-destructively monitor plant health and development","volume":"7","author":"Butler","year":"2015","journal-title":"Anal. Methods"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0065","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/nprot.2016.036","article-title":"Using Raman spectroscopy to characterize biological materials","volume":"11","author":"Butler","year":"2016","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0070","doi-asserted-by":"crossref","first-page":"3066","DOI":"10.1016\/j.watres.2008.02.021","article-title":"The inhibitory effects of silver nanoparticles, silver ions, and silver chloride colloids on microbial growth","volume":"42","author":"Choi","year":"2008","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0075","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.chemosphere.2013.01.058","article-title":"The role of plant metabolism in the mutagenic and cytotoxic effects of four organophosphorus insecticides in Salmonella typhimurium and in human cell lines","volume":"92","author":"Cort\u00e9s-Eslava","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0080","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1177\/0748233708089040","article-title":"Genotoxicity induced by pesticide mixtures: in-vitro studies on human peripheral blood lymphocytes","volume":"23","author":"Das","year":"2007","journal-title":"Toxicol. Ind. Health"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0085","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1191\/096032701682693062","article-title":"Mechanisms of chromium toxicity, carcinogenicity and allergenicity: review of the literature from 1985 to 2000","volume":"20","author":"Dayan","year":"2001","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0090","first-page":"6185","article-title":"Cytotoxicity of monocrotophos on fresh water ciliate, Paramecium caudatum","volume":"8","author":"Dixit","year":"2019","journal-title":"J. Glob. Biosci."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0095","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1590\/S0103-50532010000600002","article-title":"Potential use of silver nanoparticles on pathogenic bacteria, their toxicity and possible mechanisms of action","volume":"21","author":"Dur\u00e1n","year":"2010","journal-title":"J. Braz. Chem. Soc."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0100","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/tox.22688","article-title":"Modulatory effect of Turnera diffusa against testicular toxicity induced by fenitrothion and\/or hexavalent chromium in rats","volume":"34","author":"El-Demerdash","year":"2019","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0105","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1083\/jcb.200409170","article-title":"Hydrogen peroxide as a signal controlling plant programmed cell death","volume":"168","author":"Gechev","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0110","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/03602530600570040","article-title":"Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells","volume":"38","author":"Hanukoglu","year":"2006","journal-title":"Drug Metab. Rev."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0115","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1039\/C3AN01649H","article-title":"Mid-infrared spectroscopic assessment of nanotoxicity in gram-negative vs. gram-positive bacteria","volume":"139","author":"Heys","year":"2014","journal-title":"Analyst"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0120","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.chemosphere.2011.11.061","article-title":"Alterations of protein profile in zebrafish liver cells exposed to methyl parathion: a membrane proteomics approach","volume":"87","author":"Huang","year":"2012","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0125","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9629102","article-title":"The possible role of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 on locomotor activity and oxidative stress in a rotenone-induced zebrafish model of Parkinson\u2019s disease","volume":"2021","author":"Ilie","year":"2021","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"10","key":"10.1016\/j.scitotenv.2023.167057_bb0130","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.3390\/antiox11102040","article-title":"Assessing the neurotoxicity of a sub-optimal dose of rotenone in zebrafish (Danio rerio) and the possible neuroactive potential of valproic acid, combination of levodopa and carbidopa, and lactic acid Bacteria strains","volume":"11","author":"Ilie","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0135","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1081\/DCT-120030725","article-title":"Effect of organophosphorus and organochlorine pesticides (monochrotophos, chlorpyriphos, dimethoate, and endosulfan) on human lymphocytes in-vitro","volume":"27","author":"Jamil","year":"2004","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0140","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s10529-014-1674-3","article-title":"Use of a whole-cell bioreporter, Acinetobacter baylyi, to estimate the genotoxicity and bioavailability of chromium(VI)-contaminated soils","volume":"37","author":"Jiang","year":"2015","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0145","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jhazmat.2018.08.060","article-title":"Impacts of heavy metals and soil properties at a Nigerian e-waste site on soil microbial community","volume":"362","author":"Jiang","year":"2019","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0150","doi-asserted-by":"crossref","first-page":"134299","DOI":"10.1016\/j.scitotenv.2019.134299","article-title":"Antagonistic effects in zebrafish (Danio rerio) behavior and oxidative stress induced by toxic metals and deltamethrin acute exposure","volume":"698","author":"Jijie","year":"2020","journal-title":"Sci. Total Environ."},{"issue":"5","key":"10.1016\/j.scitotenv.2023.167057_bb0155","doi-asserted-by":"crossref","first-page":"4952","DOI":"10.3390\/ijms24054952","article-title":"Effects of single and combined ciprofloxacin and lead treatments on zebrafish behavior, oxidative stress, and elements content","volume":"24","author":"Jijie","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0160","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1039\/c7ib00009j","article-title":"Fingerprinting microbiomes towards screening for microbial antibiotic resistance","volume":"9","author":"Jin","year":"2017","journal-title":"Integr. Biol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0165","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1039\/C8AY00011E","article-title":"Spectrochemical determination of unique bacterial responses following long-term low-level exposure to antimicrobials","volume":"10","author":"Jin","year":"2018","journal-title":"Anal. Methods"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0170","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1039\/C7AN01800B","article-title":"Spectrochemical analyses of growth phase-related bacterial responses to low (environmentally-relevant) concentrations of tetracycline and nanoparticulate silver","volume":"143","author":"Jin","year":"2018","journal-title":"Analyst"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0175","doi-asserted-by":"crossref","first-page":"4291","DOI":"10.1021\/acs.analchem.2c03908","article-title":"Toxicity characterization of environment-related pollutants using a biospectroscopy\u2013bioreporter-coupling approach: potential for real-world toxicity determination and source apportionment of multiple pollutants","volume":"95","author":"Jin","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0180","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.neuro.2007.08.001","article-title":"Impaired mitochondrial energy metabolism and neuronal apoptotic cell death after chronic dichlorvos (OP) exposure in rat brain","volume":"28","author":"Kaur","year":"2007","journal-title":"NeuroToxicology"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0185","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1021\/pr101067u","article-title":"Biospectroscopy to metabolically profile biomolecular structure: a multistage approach linking computational analysis with biomarkers","volume":"10","author":"Kelly","year":"2011","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0190","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.envpol.2007.06.056","article-title":"Health risks of heavy metals in contaminated soils and food crops irrigated with wastewater in Beijing, China","volume":"152","author":"Khan","year":"2008","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0195","doi-asserted-by":"crossref","first-page":"111922","DOI":"10.1016\/j.ecoenv.2021.111922","article-title":"Human health risk visualization of potentially toxic elements in farmland soil: a combined method of source and probability","volume":"211","author":"Kong","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0200","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0887-2333(01)00090-X","article-title":"In vitro cytotoxicity of the organophosphorus pesticide parathion to FG-9307 cells","volume":"15","author":"Li","year":"2001","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0205","doi-asserted-by":"crossref","first-page":"10005","DOI":"10.1021\/es4017848","article-title":"Dose-related alterations of carbon nanoparticles in mammalian cells detected using biospectroscopy: potential for real-world effects","volume":"47","author":"Li","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0210","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.scitotenv.2013.08.090","article-title":"A review of soil heavy metal pollution from mines in China: pollution and health risk assessment","volume":"468","author":"Li","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0215","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.envint.2005.05.042","article-title":"Impacts of sewage irrigation on heavy metal distribution and contamination in Beijing, China","volume":"31","author":"Liu","year":"2005","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0220","doi-asserted-by":"crossref","first-page":"10926","DOI":"10.1021\/acs.est.9b03237","article-title":"cDNA library for mining functional genes in Sedum alfredii Hance related to cadmium tolerance and characterization of the roles of a novel SaCTP2 gene in enhancing cadmium hyperaccumulation","volume":"53","author":"Liu","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0225","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1016\/j.scitotenv.2018.11.213","article-title":"Separate and combined effects of glyphosate and copper on growth and antioxidative enzymes in Salvinia natans (L.) All","volume":"655","author":"Liu","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0230","doi-asserted-by":"crossref","first-page":"121546","DOI":"10.1016\/j.envpol.2023.121546","article-title":"Functional characterization of a DNA-damage repair\/tolerance 100 (DRT100) gene in Sedum alfredii Hance for genome stability maintenance and Cd hypertolerance","volume":"327","author":"Liu","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0235","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.jes.2022.04.023","article-title":"Organophosphate pesticides an emerging environmental contaminant: pollution, toxicity, bioremediation progress, and remaining challenges","volume":"127","author":"Mali","year":"2023","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0240","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1089\/cmb.2007.0057","article-title":"Identifying variables responsible for clustering in discriminant analysis of data from infrared microspectroscopy of a biological sample","volume":"14","author":"Martin","year":"2007","journal-title":"J. Comput. Biol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0245","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1038\/nprot.2010.133","article-title":"Distinguishing cell types or populations based on the computational analysis of their infrared spectra","volume":"5","author":"Martin","year":"2010","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0250","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1038\/s41596-019-0150-x","article-title":"Standardization of complex biologically derived spectrochemical datasets","volume":"14","author":"Morais","year":"2019","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0255","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1080\/05704920701551530","article-title":"Raman spectroscopy of biological tissues","volume":"42","author":"Movasaghi","year":"2007","journal-title":"Appl. Spectrosc. Rev."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0260","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.chemosphere.2014.04.083","article-title":"Trace metals and persistent organic pollutants in sediments from river-reservoir systems in Democratic Republic of Congo (DRC): spatial distribution and potential ecotoxicological effects","volume":"111","author":"Mwanamoki","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0265","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0378-4274(01)00480-5","article-title":"Food contamination by metals and pesticides in the European Union. Should we worry?","volume":"127","author":"Nasreddine","year":"2002","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0270","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2478\/intox-2013-0014","article-title":"Assessment of genotoxic potential of the insecticide Dichlorvos using cytogenetic assay","volume":"6","author":"Nazam","year":"2013","journal-title":"Interdiscip. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0275","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1002\/tox.20748","article-title":"Evaluation of DNA damage and cytotoxicity induced by three commonly used organophosphate pesticides individually and in mixture, in rat tissues","volume":"28","author":"Ojha","year":"2013","journal-title":"Environ. Toxicol."},{"issue":"23","key":"10.1016\/j.scitotenv.2023.167057_bb0280","doi-asserted-by":"crossref","first-page":"12714","DOI":"10.3390\/ijms222312714","article-title":"Vitamin C mitigates oxidative stress and behavioral impairments induced by deltamethrin and lead toxicity in zebrafish","volume":"22","author":"Paduraru","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0285","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s11356-016-7664-3","article-title":"Organophosphate pesticide in agricultural soils from the Yangtze River Delta of China: concentration, distribution, and risk assessment","volume":"25","author":"Pan","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0290","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1016\/j.tiv.2007.05.009","article-title":"In vitro induction of cytotoxicity and DNA strand breaks in CHO cells exposed to cypermethrin, pendimethalin and dichlorvos","volume":"21","author":"Patel","year":"2007","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0295","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.envint.2019.01.067","article-title":"Heavy metals in food crops: health risks, fate, mechanisms, and management","volume":"125","author":"Rai","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0300","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ceb.2014.09.010","article-title":"ROS-dependent signal transduction","volume":"33","author":"Reczek","year":"2015","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0305","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.aca.2005.12.067","article-title":"Recent advances in biosensor techniques for environmental monitoring","volume":"568","author":"Rogers","year":"2006","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0310","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1007\/s00254-002-0694-9","article-title":"Heavy metals distribution in agricultural topsoils in urban area","volume":"43","author":"Romic","year":"2003","journal-title":"Environ. Geol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0315","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1080\/14634988.2013.858587","article-title":"Metal and pesticide pollution scenario in Ganga River system","volume":"16","author":"Samanta","year":"2013","journal-title":"Aquat. Ecosyst. Health Manag."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0320","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3126\/njst.v10i0.2959","article-title":"Oligodynamic action of silver, copper and brass on enteric bacteria isolated from water of Kathmandu Valley","volume":"10","author":"Shrestha","year":"2009","journal-title":"Nepal J. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0325","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3389\/fchem.2017.00070","article-title":"Synergistic effects of heavy metals and pesticides in living systems","volume":"5","author":"Singh","year":"2017","journal-title":"Front. Chem."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0330","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/BF01140573","article-title":"Bacterial interactions with silver","volume":"3","author":"Slawson","year":"1990","journal-title":"Biol. Met."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0335","doi-asserted-by":"crossref","first-page":"7931","DOI":"10.1021\/es901349r","article-title":"Optimization of bacterial whole cell bioreporters for toxicity assay of environmental samples","volume":"43","author":"Song","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0340","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.envpol.2014.08.024","article-title":"A whole-cell bioreporter approach for the genotoxicity assessment of bioavailability of toxic compounds in contaminated soil in China","volume":"195","author":"Song","year":"2014","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0345","first-page":"160","article-title":"Evaluation of cytotoxicity, oxidative stress, nuclear changes and proinflammatory cytokines induced by monocrotophos in human keratinocyte cells in vitro","volume":"7","author":"Soundararajan","year":"2015","journal-title":"Int. J. Pharm. Pharm. Sci."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0350","series-title":"Oxidative Mechanisms in the Toxicity of Chromium and Cadmium Ions","first-page":"12","volume":"20","author":"Stohs","year":"2001"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0355","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1093\/bioinformatics\/btt084","article-title":"IRootLab: a free and open-source MATLAB toolbox for vibrational biospectroscopy data analysis","volume":"29","author":"Trevisan","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0360","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s00204-004-0616-6","article-title":"Effects of pesticides on human peripheral lymphocytes in vitro: induction of DNA damage","volume":"79","author":"Undeger","year":"2005","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0365","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.cotox.2020.01.001","article-title":"Heavy metal and pesticide exposure: a mixture of potential toxicity and carcinogenicity","volume":"19","author":"Wallace","year":"2020","journal-title":"Curr. Opin. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0370","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jhazmat.2014.11.017","article-title":"Ternary toxicological interactions of insecticides, herbicides, and a heavy metal on the earthworm Eisenia fetida","volume":"284","author":"Wang","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0375","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.microc.2009.09.014","article-title":"A review of heavy metal contaminations in urban soils, urban road dusts and agricultural soils from China","volume":"94","author":"Wei","year":"2010","journal-title":"Microchem. J."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0380","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.tox.2017.04.008","article-title":"Metabolomic analysis for combined hepatotoxicity of chlorpyrifos and cadmium in rats","volume":"384","author":"Xu","year":"2017","journal-title":"Toxicology"},{"key":"10.1016\/j.scitotenv.2023.167057_bb0385","doi-asserted-by":"crossref","first-page":"120031","DOI":"10.1016\/j.envpol.2022.120031","article-title":"Bioremediation of hazardous pollutants from agricultural soils: a sustainable approach for waste management towards urban sustainability","volume":"312","author":"Yaashikaa","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0390","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.pestbp.2010.02.004","article-title":"Monocrotophos induced lipid peroxidation and oxidative DNA damage in rat tissues","volume":"97","author":"Yaduvanshi","year":"2010","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0395","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1751-7915.2010.00228.x","article-title":"Functionalization of whole-cell bacterial reporters with magnetic nanoparticles","volume":"4","author":"Zhang","year":"2011","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0400","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1751-7915.2011.00301.x","article-title":"Whole-cell bacterial bioreporter for actively searching and sensing of alkanes and oil spills","volume":"5","author":"Zhang","year":"2012","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0405","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.watres.2012.11.038","article-title":"Whole cell bioreporter application for rapid detection and evaluation of crude oil spill in seawater caused by Dalian oil tank explosion","volume":"47","author":"Zhang","year":"2013","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2023.167057_bb0410","doi-asserted-by":"crossref","first-page":"12165","DOI":"10.1038\/s41598-017-12437-w","article-title":"Uptake and translocation of polycyclic aromatic hydrocarbons (PAHs) and heavy metals by maize from soil irrigated with wastewater","volume":"7","author":"Zhang","year":"2017","journal-title":"Sci. Rep."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896972305684X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896972305684X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:53:27Z","timestamp":1787838807000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004896972305684X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":82,"alternative-id":["S004896972305684X"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.167057","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synergistic\/antagonistic toxicity characterization and source-apportionment of heavy metals and organophosphorus pesticides by the biospectroscopy-bioreporter-coupling approach","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.167057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"167057"}}