{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:15:01Z","timestamp":1790709301133,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21607108"],"award-info":[{"award-number":["21607108"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013804","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013804","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.scitotenv.2023.168240","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T23:25:25Z","timestamp":1698794725000},"page":"168240","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Distribution, fate and removal efficiency of anthelmintic drugs in wastewater treatment plants"],"prefix":"10.1016","volume":"908","author":[{"given":"Li","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Gan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijun","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2023.168240_bb0005","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s12917-015-0442-5","article-title":"Comparative pharmacokinetics and bioavailability of albendazole sulfoxide in sheep and goats, and dose-dependent plasma disposition in goats","volume":"11","author":"Aksit","year":"2015","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0010","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/698_2017_5","article-title":"Hospital wastewater treatments adopted in Asia, Africa, and Australia","volume":"60","author":"Al Aukidy","year":"2017","journal-title":"Hosp. Wastew."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0015","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s00216-010-4004-1","article-title":"Determination of multi-class pharmaceuticals in wastewater by liquid chromatography-tandem mass spectrometry (LC-MS-MS)","volume":"398","author":"Babi\u0107","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.116106","article-title":"Environmental risk assessment of the anthelmintic albendazole in eastern Africa, based on a systematic review","volume":"269","author":"Belew","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.jece.2021.105548","article-title":"Investigation of pharmaceuticals in a conventional wastewater treatment plant: removal efficiency, seasonal variation and impact of a nearby hospital","volume":"9","author":"Bijlsma","year":"2021","journal-title":"J. Environ. Chem. Eng."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0030","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.scitotenv.2018.10.290","article-title":"Pharmaceuticals as chemical markers of wastewater contamination in the vulnerable area of the Ebro Delta (Spain)","volume":"652","author":"\u010celi\u0107","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0035","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1007\/s00216-012-6444-2","article-title":"Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatography\u2013tandem mass spectrometry","volume":"404","author":"Chen","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112360","article-title":"Occurrence and risk assessment of anthelmintics in Tuojiang River in Sichuan, China","volume":"220","author":"Chen","year":"2021","journal-title":"Ecotoxicology and Environmental Safety"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0045","doi-asserted-by":"crossref","first-page":"20521","DOI":"10.1007\/s11356-017-9660-7","article-title":"Multi-class determination of pharmaceuticals in wastewaters by solid-phase extraction and liquid chromatography tandem mass spectrometry with matrix effect study","volume":"24","author":"\u010cizmi\u0107","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchromb.2006.07.046","article-title":"Review of methodology for the determination of benzimidazole residues in biological matrices","volume":"845","author":"Danaher","year":"2007","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0055","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.aca.2015.04.013","article-title":"Multi-residue determination of 115 veterinary drugs and pharmaceutical residues in milk powder, butter, fish tissue and eggs using liquid chromatography\u2013tandem mass spectrometry","volume":"880","author":"Dasenaki","year":"2015","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0060","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.scitotenv.2019.04.410","article-title":"Concentration and reduction of antibiotic residues in selected wastewater treatment plants and receiving waterbodies in Durban, South Africa","volume":"678","author":"Faleye","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114651","article-title":"Residues of an anthelmintic veterinary drug (closantel) detected in red foxes (Vulpes vulpes) in Scotland","volume":"253","author":"Giergiel","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0070","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.scitotenv.2006.07.039","article-title":"Fate of sulfonamides, macrolides, and trimethoprim in different wastewater treatment technologies","volume":"372","author":"G\u00f6bel","year":"2007","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0075","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.vetpar.2007.06.028","article-title":"Comparative plasma disposition of fenbendazole, oxfendazole and albendazole in dogs","volume":"148","author":"Gokbulut","year":"2007","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0080","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.jhazmat.2010.10.005","article-title":"Improved removal of estrogenic and pharmaceutical compounds in sewage effluent by full scale granular activated carbon: impact on receiving river water","volume":"185","author":"Grover","year":"2011","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jfca.2022.104959","article-title":"An ultrahigh-performance liquid chromatography-fluorescence detection (UHPLC-FLD) method for simultaneous determination of albendazole and its three metabolites in poultry eggs","volume":"115","author":"Guan","year":"2023","journal-title":"J. Food Compos. Anal."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0090","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1007\/s00128-012-0755-z","article-title":"Red fox (Vulpes vulpes Linnaeus, 1758) as biological Indicator for environmental pollution in Hungary","volume":"89","author":"Heltai","year":"2012","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0095","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.trac.2011.06.023","article-title":"Analysis, occurrence and fate of anthelmintics and their transformation products in the environment","volume":"31","author":"Horvat","year":"2012","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0100","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.watres.2010.11.010","article-title":"Occurrence, partition and removal of pharmaceuticals in sewage water and sludge during wastewater treatment","volume":"45","author":"Jelic","year":"2011","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0105","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.aca.2008.10.072","article-title":"New method for the analysis of flukicide and other anthelmintic residues in bovine milk and liver using liquid chromatography\u2013tandem mass spectrometry","volume":"637","author":"Kinsella","year":"2009","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0110","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.scitotenv.2018.12.258","article-title":"Occurrence and distribution of pharmaceutical and personal care products, artificial sweeteners, and pesticides in groundwater from an agricultural area in Korea","volume":"659","author":"Lee","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0115","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1002\/1097-0142(19801115)46:10<2185::AID-CNCR2820461015>3.0.CO;2-5","article-title":"Cellular immune modulation after a single high dose of levamisole in patients with carcinoma","volume":"46","author":"Lewinski","year":"1980","journal-title":"Cancer"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.137516","article-title":"Determination of 19 anthelmintics in environmental water and sediment using an optimized PLE and SPE method coupled with UHPLC-MS\/MS","volume":"719","author":"Li","year":"2020","journal-title":"Sci. Total Environ."},{"issue":"Suppl","key":"10.1016\/j.scitotenv.2023.168240_bb0125","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/ieam.96","article-title":"Environmental risk assessment of ivermectin: a case study","volume":"6","author":"Liebig","year":"2010","journal-title":"Integr. Environ. Assess. Manag."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0130","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.talanta.2011.11.082","article-title":"Development and validation of a multiclass method for the determination of veterinary drug residues in chicken by ultra high performance liquid chromatography\u2013tandem mass spectrometry","volume":"89","author":"Lopes","year":"2012","journal-title":"Talanta"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.144804","article-title":"An analysis of the spatio-temporal occurrence of anthelmintic veterinary drug residues in groundwater","volume":"769","author":"Mooney","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.138343","article-title":"Albendazole from ovine excrements in soil and plants under real agricultural conditions: distribution, persistence, and effects","volume":"324","author":"Navr\u00e1tilov\u00e1","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0145","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.jenvman.2018.11.121","article-title":"Benzimidazoles in wastewater: analytical method development, monitoring and degradation by photolysis and ozonation","volume":"232","author":"Porto","year":"2019","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0150","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3109\/00498254.2015.1060370","article-title":"Metabolism of drugs and other xenobiotics in giant liver fluke (Fascioloides magna)","volume":"46","author":"Prchal","year":"2016","journal-title":"Xenobiotica"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0155","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jhazmat.2013.01.007","article-title":"Evaluation of pharmaceuticals and personal care products with emphasis on anthelmintics in human sanitary waste, sewage, hospital wastewater, livestock wastewater and receiving water","volume":"248-249","author":"Sim","year":"2013","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0160","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.scitotenv.2015.01.098","article-title":"Occurrence and fate of select psychoactive pharmaceuticals and antihypertensives in two wastewater treatment plants in New York State, USA","volume":"514","author":"Subedi","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0165","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.chemosphere.2011.04.063","article-title":"Use of fugacity model to analyze temperature-dependent removal of micro-contaminants in sewage treatment plants","volume":"84","author":"Thompson","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0170","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.chroma.2008.01.012","article-title":"Validation of a solid-phase extraction and liquid chromatography-electrospray tandem mass spectrometric method for the determination of nine basic pharmaceuticals in wastewater and surface water samples","volume":"1182","author":"Van De Steene","year":"2008","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0175","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1021\/acs.est.5b05516","article-title":"Fate of parabens and their metabolites in two wastewater treatment plants in New York State, United States","volume":"50","author":"Wang","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0180","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.jpba.2009.02.032","article-title":"Stability of ricobendazole in aqueous solutions","volume":"49","author":"Wu","year":"2009","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0185","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.proenv.2011.12.131","article-title":"Study of treating high Ammonia-N domestic wastewater with CASS process","volume":"11","author":"Ying","year":"2011","journal-title":"Procedia Environ. Sci."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0190","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.chemosphere.2008.06.001","article-title":"Occurrence and removal of endocrine disrupting chemicals in wastewater","volume":"73","author":"Zhang","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.168240_bb0195","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.marpolbul.2013.05.007","article-title":"Fate of antibiotics during wastewater treatment and antibiotic distribution in the effluent-receiving waters of the Yellow Sea, northern China","volume":"73","author":"Zhang","year":"2013","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114113","article-title":"Efficient multiresidue determination method for 168 pharmaceuticals and metabolites: optimization and application to raw wastewater, wastewater effluent, and surface water in Beijing, China","volume":"261","author":"Zhang","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2023.168240_bb0205","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.chemosphere.2013.10.091","article-title":"Analysis of anthelmintics in surface water by ultra high performance liquid chromatography coupled to quadrupole linear ion trap tandem mass spectrometry","volume":"99","author":"Zrn\u010di\u0107","year":"2014","journal-title":"Chemosphere"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723068675?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723068675?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T02:09:45Z","timestamp":1743473385000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969723068675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":41,"alternative-id":["S0048969723068675"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.168240","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distribution, fate and removal efficiency of anthelmintic drugs in wastewater treatment plants","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.168240","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"168240"}}