{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:37:12Z","timestamp":1792427832606,"version":"4.5.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22306150"],"award-info":[{"award-number":["22306150"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFA0901104"],"award-info":[{"award-number":["2018YFA0901104"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.scitotenv.2023.169291","type":"journal-article","created":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T14:54:10Z","timestamp":1702652050000},"page":"169291","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"special_numbering":"C","title":["Stable isotope-assisted mass spectrometry reveals in vivo distribution, metabolism, and excretion of tire rubber-derived 6PPD-quinone in mice"],"prefix":"10.1016","volume":"912","author":[{"given":"Jing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guodong","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuyue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenlan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongwei","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.scitotenv.2023.169291_bb0005","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1021\/tx800139z","article-title":"Application of stable isotope-labeled compounds in metabolism and in metabolism-mediated toxicity studies","volume":"21","author":"Abdul","year":"2008","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0010","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1139\/cjfas-2020-0240","article-title":"Acute cerebrovascular effects in juvenile coho salmon exposed to roadway runoff","volume":"78","author":"Blair","year":"2021","journal-title":"Can. J. Fish. Aquat. Sci."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0015","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1021\/acs.estlett.2c00050","article-title":"Acute toxicity of the tire rubber-derived chemical 6PPD-quinone to four fishes of commercial, cultural, and ecological importance","volume":"9","author":"Brinkmann","year":"2022","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0020","unstructured":"Cai, Z., Cao, G., 2021. A method for synthesis of isotopically labeled N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone. Patent No: ZL202110938238.3."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0025","doi-asserted-by":"crossref","first-page":"4142","DOI":"10.1021\/acs.est.1c07376","article-title":"New evidence of rubber-derived quinones in water, air, and soil","volume":"56","author":"Cao","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2022.116756","article-title":"Mass spectrometry analysis of a ubiquitous tire rubber-derived quinone in the environment","volume":"157","author":"Cao","year":"2022","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0035","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1021\/acs.estlett.1c00682","article-title":"Occurrences of tire rubber-derived contaminants in cold-climate urban runoff","volume":"8","author":"Challis","year":"2021","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0040","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.reprotox.2011.07.002","article-title":"Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys","volume":"33","author":"Chang","year":"2012","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0045","doi-asserted-by":"crossref","first-page":"7255","DOI":"10.1021\/acs.analchem.2c00500","article-title":"Global tracking of transformation products of environmental contaminants by 2H-labeled stable isotope-assisted metabolomics","volume":"94","author":"Chen","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.162681","article-title":"Human exposure to short-chain chlorinated paraffins and organophosphate flame retardants in relation to paired multiple sources","volume":"875","author":"Choo","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0055","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.envpol.2010.09.036","article-title":"Toxicity profile of labile preservative bronopol in water: the role of more persistent and toxic transformation products","volume":"159","author":"Cui","year":"2011","journal-title":"Environ. Pollut."},{"issue":"3","key":"10.1016\/j.scitotenv.2023.169291_bb0060","doi-asserted-by":"crossref","first-page":"436","DOI":"10.5254\/1.3548174","article-title":"Rubber vulcanizates degradation and stabilization","volume":"80","author":"Datta","year":"2007","journal-title":"Rubber Chem. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146667","article-title":"Targeted and suspect screening of plasticizers in house dust to assess cumulative human exposure risk","volume":"781","author":"Demirtepe","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0070","doi-asserted-by":"crossref","first-page":"2876","DOI":"10.1021\/es902149b","article-title":"Distribution of PCBs, their hydroxylated metabolites, and other phenolic contaminants in human serum from two European countries","volume":"44","author":"Dirtu","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0075","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1021\/acs.estlett.2c00821","article-title":"First report on the occurrence of N-(1,3-dimethylbutyl)-N\u2032-phenyl-p-phenylenediamine (6PPD) and 6PPD-quinone as pervasive pollutants in human urine from South China","volume":"9","author":"Du","year":"2022","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.161836","article-title":"Oral exposure to tire rubber-derived contaminant 6PPD and 6PPD-quinone induce hepatotoxicity in mice","volume":"869","author":"Fang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0090","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1177\/0192623316677327","article-title":"Sex differences in human and animal toxicology:toxicokinetics","volume":"45","author":"Gochfeld","year":"2017","journal-title":"Toxicol. Pathol."},{"issue":"41","key":"10.1016\/j.scitotenv.2023.169291_bb2405","doi-asserted-by":"crossref","first-page":"15598","DOI":"10.1021\/acs.est.3c02819","article-title":"Uptake and biotransformation of the tire rubber-derived contaminants 6-PPD and 6-PPD quinone in the zebrafish embryo (danio rerio)","volume":"57","author":"Grasse","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0095","doi-asserted-by":"crossref","first-page":"10940","DOI":"10.1021\/acs.est.3c01040","article-title":"Tire-derived transformation product 6PPD-quinone induces mortality and transcriptionally disrupts vascular permeability pathways in developing coho salmon","volume":"57","author":"Greer","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0100","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1080\/00498250110119117","article-title":"Tissue disposition, excretion and metabolism of 2,2\u2032,4,4\u2032,5-pentabromodiphenyl ether (BDE-99) in the male Sprague-Dawley rat","volume":"32","author":"Hakk","year":"2002","journal-title":"Xenobiotica"},{"key":"10.1016\/j.scitotenv.2023.169291_bb0105","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1016\/S2542-5196(22)00254-6","article-title":"Antibiotic concentrations and antibiotic resistance in aquatic environments of the WHO Western Pacific and South-East Asia regions: a systematic review and probabilistic environmental hazard assessment","volume":"7","author":"Hanna","year":"2023","journal-title":"Lancet Planet. Health."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.164842","article-title":"Four-week repeated exposure to tire-derived 6-PPD quinone causes multiple organ injury in male BALB\/c mice","volume":"894","author":"He","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0115","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1021\/acs.estlett.2c00683","article-title":"The tire-derived chemical 6PPD-quinone is lethally toxic to the white-spotted char Salvelinus leucomaenis pluvius but not to two other salmonid species","volume":"9","author":"Hiki","year":"2022","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0120","first-page":"901","article-title":"Chemical characteristics, leaching, and stability of the ubiquitous tire rubber-derived toxicant 6PPD-quinone","volume":"25","author":"Hu","year":"2023","journal-title":"Environ. Sci.: Processes Impacts"},{"key":"10.1016\/j.scitotenv.2023.169291_bb0125","doi-asserted-by":"crossref","first-page":"4940","DOI":"10.1021\/acs.est.2c08644","article-title":"Exposure to 6-PPD quinone at environmentally relevant concentrations causes abnormal locomotion behaviors and neurodegeneration in Caenorhabditis elegans","volume":"57","author":"Hua","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0130","doi-asserted-by":"crossref","first-page":"7808","DOI":"10.1021\/acs.est.6b01698","article-title":"Isomer\u2013specific distribution of perfluoroalkyl substances in blood","volume":"50","author":"Jin","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb2400","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1021\/acs.estlett.1c00148","article-title":"Occurrence of substituted p-phenylenediamine antioxidants in dusts","volume":"8","author":"Huang","year":"2021","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0135","doi-asserted-by":"crossref","first-page":"10361","DOI":"10.1021\/acs.est.3c01448","article-title":"Ubiquity of amino accelerators and antioxidants in road dust from multiple land types: targeted and nontargeted analysis","volume":"57","author":"Jin","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0140","doi-asserted-by":"crossref","first-page":"2828","DOI":"10.1021\/es901781p","article-title":"Clearance of polychlorinated biphenyl atropisomers is enantioselective in female C57Bl\/6 mice","volume":"44","author":"Kania-Korwel","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0145","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1289\/ehp.1205485","article-title":"Toxicological function of adipose tissue: focus on persistent organic pollutants","volume":"121","author":"La Merrill","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0150","doi-asserted-by":"crossref","first-page":"11706","DOI":"10.1021\/acs.est.0c05077","article-title":"Synthetic phenolic antioxidants: a review of environmental occurrence, fate, human exposure, and toxicity","volume":"54","author":"Liu","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149916","article-title":"Transformation products of pharmaceuticals in the environment: their fate, (eco)toxicity and bioaccumulation potential","volume":"802","author":"Maculewicz","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0160","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1021\/acs.estlett.2c00431","article-title":"Exposure to the tire rubber-derived contaminant 6PPD-quinone causes mitochondrial dysfunction in vitro","volume":"9","author":"Mahoney","year":"2022","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0165","doi-asserted-by":"crossref","first-page":"4642","DOI":"10.1073\/pnas.1919563117","article-title":"Bisphenol A and bisphenol S disruptions of the mouse placenta and potential effects on the placenta-brain axis","volume":"117","author":"Mao","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0170","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/S0045-6535(00)00442-2","article-title":"An overview of TCDD half-life in mammals and its correlation to body weight","volume":"43","author":"Miniero","year":"2001","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2023.169291_bb0175","doi-asserted-by":"crossref","first-page":"e368","DOI":"10.1016\/S2542-5196(17)30166-3","article-title":"Cardiorespiratory health effects of particulate ambient air pollution exposure in low-income and middle-income countries: a systematic review and meta-analysis","volume":"1","author":"Newell","year":"2017","journal-title":"Lancet Planet. Health."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0180","doi-asserted-by":"crossref","first-page":"12541","DOI":"10.1021\/acs.analchem.3c02833","article-title":"H\/D exchange coupled with 2H-labeled stable isotope-assisted metabolomics discover transformation products of contaminants of emerging concern","volume":"95","author":"Qian","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0185","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1289\/ehp.1003385","article-title":"Comparison of serum bisphenol A concentrations in mice exposed to bisphenol A through the diet versus oral bolus exposure","volume":"119","author":"Sieli","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0190","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/nrendo.2010.87","article-title":"Environmental causes of cancer: endocrine disruptors as carcinogens","volume":"6","author":"Soto","year":"2010","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0195","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1021\/acs.chemrestox.5b00097","article-title":"Tissue distribution, excretion and pharmacokinetics of the environmental pollutant dibenzo[def,p]chrysene in mice","volume":"28","author":"Sun","year":"2015","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0200","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1038\/s41590-020-0802-6","article-title":"Environmental pollutants and the immune response","volume":"21","author":"Suzuki","year":"2020","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0205","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1289\/ehp.1002514","article-title":"Similarity of bisphenol A pharmacokinetics in rhesus monkeys and mice: relevance for human exposure","volume":"119","author":"Taylor","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0210","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.envint.2015.06.008","article-title":"Pharmacokinetics of bisphenol A in humans following a single oral administration","volume":"83","author":"Thayer","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0215","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1126\/science.abd6951","article-title":"A ubiquitous tire rubber-derived chemical induces acute mortality in coho salmon","volume":"371","author":"Tian","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2023.169291_bb0220","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1021\/acs.estlett.1c00910","article-title":"6PPD-quinone: revised toxicity assessment and quantification with a commercial standard","volume":"9","author":"Tian","year":"2022","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0225","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1021\/acs.estlett.2c00484","article-title":"p-Phenylenediamine-derived quinones as new contributors to the oxidative potential of fine particulate matter","volume":"9","author":"Wang","year":"2022","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0230","doi-asserted-by":"crossref","first-page":"10629","DOI":"10.1021\/acs.est.2c02463","article-title":"Beyond substituted p-phenylenediamine antioxidants: prevalence of their quinone derivatives in PM2.5","volume":"56","author":"Wang","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0235","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/ansa.202200038","article-title":"Recent applications of mass spectrometry in the analysis of transformation products of emerging contaminants in PM2.5","volume":"4","author":"Wang","year":"2023","journal-title":"Anal. Sci. Adv."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.161373","article-title":"A new toxicity mechanism of N-(1,3-dimethylbutyl)-N\u2032-phenyl-p-phenylenediamine quinone: formation of DNA adducts in mammalian cells and aqueous organisms","volume":"866","author":"Wu","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0245","doi-asserted-by":"crossref","first-page":"14595","DOI":"10.3390\/ijerph192114595","article-title":"Rubber antioxidants and their transformation products: environmental occurrence and potential impact","volume":"19","author":"Xu","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.scitotenv.2023.169291_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105056","article-title":"Biomonitoring of organophosphate triesters and diesters in human blood in Jiangsu Province, eastern China: occurrences, associations, and suspect screening of novel metabolites","volume":"131","author":"Ya","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0255","doi-asserted-by":"crossref","first-page":"6123","DOI":"10.1021\/acs.est.1c00616","article-title":"Significant reductive transformation of 6:2 chlorinated polyfluorooctane ether sulfonate to form hydrogen-substituted polyfluorooctane ether sulfonate and their toxicokinetics in male Sprague-Dawley rats","volume":"56","author":"Yi","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0260","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1021\/acs.est.2c07652","article-title":"Widespread occurrence and transport of p-phenylenediamines and their quinones in sediments across urban rivers, estuaries, coasts, and deep-sea regions","volume":"57","author":"Zeng","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.139862","article-title":"Tissue distribution, excretion, and metabolism of 2,6-di-tert-butyl-hydroxytoluene in mice","volume":"739","author":"Zhang","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0270","doi-asserted-by":"crossref","first-page":"4686","DOI":"10.1021\/es303808b","article-title":"Blood and urinary bisphenol A concentrations in children, adults, and pregnant women from China: partitioning between blood and urine and maternal and fetal cord blood","volume":"47","author":"Zhang","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124859","article-title":"Tetrabromobisphenol A induces THR beta-mediated inflammation and uterine injury in mice at environmentally relevant exposure concentrations","volume":"407","author":"Zhang","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0280","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1021\/acs.estlett.2c00193","article-title":"Widespread N-(1,3-dimethylbutyl)-N\u2032-phenyl-p-phenylenediamine quinone in size-fractioned atmospheric particles and dust of different indoor environments","volume":"9","author":"Zhang","year":"2022","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2023.169291_bb0285","doi-asserted-by":"crossref","first-page":"13429","DOI":"10.1021\/acs.est.3c05026","article-title":"Urine excretion, organ distribution, and placental transfer of 6PPD and 6PPD-quinone in mice and potential developmental toxicity through nuclear receptor pathways","volume":"57","author":"Zhao","year":"2023","journal-title":"Environ. Sci. Technol."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723079214?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969723079214?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T09:33:39Z","timestamp":1786959219000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969723079214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":58,"alternative-id":["S0048969723079214"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.169291","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stable isotope-assisted mass spectrometry reveals in vivo distribution, metabolism, and excretion of tire rubber-derived 6PPD-quinone in mice","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2023.169291","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"169291"}}