{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:04:23Z","timestamp":1791896663424,"version":"4.3.4"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017697","name":"Hebei Province Outstanding Youth Fund","doi-asserted-by":"publisher","award":["D2019208152"],"award-info":[{"award-number":["D2019208152"]}],"id":[{"id":"10.13039\/501100017697","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.scitotenv.2024.170788","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T21:50:48Z","timestamp":1707515448000},"page":"170788","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Antibiotic resistance genes and mobile genetic elements in different rivers: The link with antibiotics, microbial communities, and human activities"],"prefix":"10.1016","volume":"919","author":[{"given":"Lulu","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoda","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanmeng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhong","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiansheng","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.scitotenv.2024.170788_bb0010","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nrmicro2312","article-title":"Call of the wild: antibiotic resistance genes in natural environments","volume":"8","author":"Allen","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"issue":"2","key":"10.1016\/j.scitotenv.2024.170788_bb0015","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1128\/AAC.49.2.836-839.2005","article-title":"Dissemination of sulfonamide resistance genes (sul1, sul2, and sul3) in Portuguese salmonella enterica strains and relation with integrons","volume":"49","author":"Antunes","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"issue":"18","key":"10.1016\/j.scitotenv.2024.170788_bb0020","doi-asserted-by":"crossref","first-page":"6506","DOI":"10.1128\/JB.00375-06","article-title":"Functional characterization of IS1999, an IS4 family element involved in mobilization and expression of \u03b2-lactam resistance genes","volume":"188","author":"Aubert","year":"2006","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb1000","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.envint.2015.10.015","article-title":"Concentrations of antibiotics predicted to select for resistant bacteria: proposed limits for environmental regulation","volume":"86","author":"Bengtsson-Palme","year":"2016","journal-title":"Environ. Int."},{"issue":"23","key":"10.1016\/j.scitotenv.2024.170788_bb0025","doi-asserted-by":"crossref","first-page":"15734","DOI":"10.1021\/acs.est.1c02977","article-title":"What is the role of the environment in the emergence of novel antibiotic resistance genes?","volume":"55","author":"Bengtsson-Palme","year":"2021","journal-title":"A modeling approach. Environ. Sci. Technol."},{"issue":"7","key":"10.1016\/j.scitotenv.2024.170788_bb0030","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/s41579-021-00534-7","article-title":"Examining horizontal gene transfer in microbial communities","volume":"19","author":"Brito","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"issue":"1","key":"10.1016\/j.scitotenv.2024.170788_bb0035","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nmeth.3176","article-title":"Fast and sensitive protein alignment using DIAMOND","volume":"12","author":"Buchfink","year":"2015","journal-title":"Nat. Methods"},{"issue":"5","key":"10.1016\/j.scitotenv.2024.170788_bb0040","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1046\/j.1468-3083.2001.00343.x","article-title":"Chlamydial treatment failures: a persistent problem","volume":"15","author":"Byrne","year":"2001","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"5","key":"10.1016\/j.scitotenv.2024.170788_bb0045","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1073\/pnas.1616248114","article-title":"Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks","volume":"114","author":"Cerqueira","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"22","key":"10.1016\/j.scitotenv.2024.170788_bb0050","doi-asserted-by":"crossref","first-page":"12753","DOI":"10.1021\/es403818e","article-title":"Metagenomic profiles of antibiotic resistance genes (ARGs) between human impacted estuary and deep ocean sediments","volume":"47","author":"Chen","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106345","article-title":"Environmental risk characterization and ecological process determination of bacterial antibiotic resistome in lake sediments","volume":"147","author":"Chen","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0060","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.watres.2019.06.047","article-title":"Environmental media exert a bottleneck in driving the dynamics of antibiotic resistance genes in modern aquatic environment","volume":"162","author":"Chen","year":"2019","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0065","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.envint.2015.04.005","article-title":"Does human activity impact the natural antibiotic resistance background? Abundance of antibiotic resistance genes in 21 Swiss lakes","volume":"81","author":"Czekalski","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149119","article-title":"Response of microbial nitrogen transformation processes to antibiotic stress in a drinking water reservoir","volume":"797","author":"Dang","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.scitotenv.2024.170788_bb0075","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1128\/MMBR.00016-10","article-title":"Origins and evolution of antibiotic resistance","volume":"74","author":"Davies","year":"2010","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.151011","article-title":"Occurrence and distribution of antibiotics in groundwater, surface water, and sediment in Xiong\u2019an new area, China, and their relationship with antibiotic resistance genes","volume":"807","author":"Fu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0085","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.watres.2017.06.046","article-title":"Stormwater loadings of antibiotic resistance genes in an urban stream","volume":"123","author":"Garner","year":"2017","journal-title":"Water Res."},{"issue":"6","key":"10.1016\/j.scitotenv.2024.170788_bb0090","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1038\/ismej.2014.226","article-title":"Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution","volume":"9","author":"Gillings","year":"2015","journal-title":"ISME J."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0100","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.envint.2018.02.003","article-title":"Presence of antibiotic residues in various environmental compartments of Shandong province in eastern China: its potential for resistance development and ecological and human risk","volume":"114","author":"Hanna","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131208","article-title":"Mariculture affects antibiotic resistome and microbiome in the coastal environment","volume":"452","author":"He","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0110","article-title":"Homogeneous selection drives antibiotic resistome in two adjacent sub-watersheds","volume":"398","author":"Hu","year":"2020","journal-title":"China. J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0115","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.scitotenv.2019.03.168","article-title":"Occurrence and distribution of antibiotics and antibiotic resistant genes in water and sediments of urban rivers with black-odor water in Guangzhou","volume":"670","author":"Huang","year":"2019","journal-title":"South China. Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.ese.2022.100162","article-title":"Exposure to trace levels of metals and fluoroquinolones increases inflammation and tumorigenesis risk of zebrafish embryos","volume":"10","author":"Jia","year":"2022","journal-title":"Environ. Sci. Ecotechnol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146131","article-title":"Antibiotic resistance genes and mobile genetic elements in a rural river in Southeast China: occurrence, seasonal variation and association with the antibiotics","volume":"778","author":"Jiang","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"6","key":"10.1016\/j.scitotenv.2024.170788_bb0130","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1021\/acsestwater.0c00308","article-title":"What water professionals should know about antibiotics and antibiotic resistance: an overview","volume":"1","author":"Jovanovic","year":"2021","journal-title":"ACS ES&T Water"},{"key":"10.1016\/j.scitotenv.2024.170788_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106190","article-title":"Treated wastewater irrigation promotes the spread of antibiotic resistance into subsoil pore-water","volume":"146","author":"Kampouris","year":"2021","journal-title":"Environ. Int."},{"issue":"D1","key":"10.1016\/j.scitotenv.2024.170788_bb0140","doi-asserted-by":"crossref","first-page":"D109","DOI":"10.1093\/nar\/gkr988","article-title":"KEGG for integration and interpretation of large-scale molecular data sets","volume":"40","author":"Kanehisa","year":"2012","journal-title":"Nucleic Acids Res."},{"issue":"6","key":"10.1016\/j.scitotenv.2024.170788_bb0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0062712","article-title":"Occurrence and abundance of antibiotics and resistance genes in rivers, canal and near drug formulation facilities\u2013a study in Pakistan","volume":"8","author":"Khan","year":"2013","journal-title":"PloS One"},{"issue":"15","key":"10.1016\/j.scitotenv.2024.170788_bb0150","doi-asserted-by":"crossref","first-page":"E3463","DOI":"10.1073\/pnas.1717295115","article-title":"Global increase and geographic convergence in antibiotic consumption between 2000 and 2015","volume":"115","author":"Klein","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.scitotenv.2024.170788_bb0155","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1021\/es901221x","article-title":"Evidence of increasing antibiotic resistance gene abundances in archived soils since 1940","volume":"44","author":"Knapp","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0160","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.envint.2018.12.065","article-title":"Antibiotics bioremediation: perspectives on its ecotoxicity and resistance","volume":"124","author":"Kumar","year":"2019","journal-title":"Environ. Int."},{"issue":"6287","key":"10.1016\/j.scitotenv.2024.170788_bb0165","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1126\/science.352.6287.758","article-title":"Resistance fighters","volume":"352","author":"Kupferschmidt","year":"2016","journal-title":"Science"},{"issue":"9","key":"10.1016\/j.scitotenv.2024.170788_bb0170","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/nbt.2676","article-title":"Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences","volume":"31","author":"Langille","year":"2013","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0175","doi-asserted-by":"crossref","DOI":"10.1360\/nso\/20220029","article-title":"Antibiotics in global rivers","volume":"1","author":"Li","year":"2022","journal-title":"Natl. Sci. Open"},{"key":"10.1016\/j.scitotenv.2024.170788_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.117447","article-title":"Anthropogenic disturbances on antibiotic resistome along the Yarlung Tsangpo River on the Tibetan plateau: ecological dissemination mechanisms of antibiotic resistance genes to bacterial pathogens","volume":"202","author":"Liu","year":"2021","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0185","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ecoenv.2018.07.067","article-title":"Occurrence of typical antibiotics and source analysis based on PCA-MLR model in the east Dongting Lake","volume":"163","author":"Liu","year":"2018","journal-title":"China. Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0190","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.envpol.2018.12.005","article-title":"Occurrence and fate of antibiotics and antibiotic resistance genes in typical urban water of Beijing","volume":"246","author":"Liu","year":"2019","journal-title":"China. Environ. Pollut."},{"issue":"6","key":"10.1016\/j.scitotenv.2024.170788_bb0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nmicrobiol.2016.44","article-title":"Antibiotics as a selective driver for conjugation dynamics","volume":"1","author":"Lopatkin","year":"2016","journal-title":"Nat. Microbiol."},{"issue":"3","key":"10.1016\/j.scitotenv.2024.170788_bb0210","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1080\/01459740.2022.2037083","article-title":"Antibiotics and the biopolitics of sex work in Zimbabwe","volume":"41","author":"Manyau","year":"2022","journal-title":"Med. Anthropol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0215","article-title":"Microbial communities, resistance genes, and resistome risks in urban lakes of different trophic states: internal links and external influences","volume":"9","author":"Mao","year":"2023","journal-title":"J. Hazard. Mater. Adv."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0220","doi-asserted-by":"crossref","first-page":"12178","DOI":"10.1007\/s11356-020-12171-3","article-title":"Enrichment of antibiotic resistance genes (ARGs) in polyaromatic hydrocarbon\u2013contaminated soils: a major challenge for environmental health","volume":"28","author":"Maurya","year":"2021","journal-title":"Environ. Sci. Pollut. Res."},{"issue":"7","key":"10.1016\/j.scitotenv.2024.170788_bb0225","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.1128\/AAC.00419-13","article-title":"The comprehensive antibiotic resistance database","volume":"57","author":"Mcarthur","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"issue":"16","key":"10.1016\/j.scitotenv.2024.170788_bb0230","doi-asserted-by":"crossref","first-page":"6102","DOI":"10.1021\/es9038165","article-title":"Tet and sul antibiotic resistance genes in livestock lagoons of various operation type, configuration, and antibiotic occurrence","volume":"44","author":"Mckinney","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131322","article-title":"Occurrence, distribution, and risk assessment of quinolone antibiotics in municipal sewage sludges throughout China","volume":"453","author":"Meng","year":"2023","journal-title":"J. Hazard. Mater."},{"issue":"1","key":"10.1016\/j.scitotenv.2024.170788_bb0240","doi-asserted-by":"crossref","first-page":"11257","DOI":"10.1038\/ncomms11257","article-title":"Fast and sensitive taxonomic classification for metagenomics with kaiju","volume":"7","author":"Menzel","year":"2016","journal-title":"Nat. Commun."},{"issue":"405","key":"10.1016\/j.scitotenv.2024.170788_bb0245","first-page":"299","article-title":"Antimicrobial resistance: tackling a crisis for the health and wealth of nations","volume":"2000","author":"O'Neill","year":"2014","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.scitotenv.2024.170788_bb0250","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00088-17","article-title":"Mobile genetic elements associated with antimicrobial resistance","volume":"31","author":"Partridge","year":"2018","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105524","article-title":"Urbanization drives riverine bacterial antibiotic resistome more than taxonomic community at watershed scale","volume":"137","author":"Peng","year":"2020","journal-title":"Environ. Int."},{"issue":"5","key":"10.1016\/j.scitotenv.2024.170788_bb0260","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1089\/mdr.2016.0034","article-title":"Dissemination of trimethoprim\u2013sulfamethoxazole drug resistance genes associated with class 1 and class 2 integrons among gram-negative bacteria from HIV patients in South India","volume":"23","author":"Ramesh Kumar","year":"2017","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0265","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.watres.2014.11.021","article-title":"Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river","volume":"69","author":"Rodriguez-Mozaz","year":"2015","journal-title":"Water Res."},{"issue":"5","key":"10.1016\/j.scitotenv.2024.170788_bb0270","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.chemosphere.2006.03.026","article-title":"A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment","volume":"65","author":"Sarmah","year":"2006","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2024.170788_bb0275","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.chemosphere.2015.12.084","article-title":"A review of the influence of treatment strategies on antibiotic resistant bacteria and antibiotic resistance genes","volume":"150","author":"Sharma","year":"2016","journal-title":"Chemosphere"},{"issue":"1","key":"10.1016\/j.scitotenv.2024.170788_bb0280","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.watres.2012.09.046","article-title":"Metagenomic insights into chlorination effects on microbial antibiotic resistance in drinking water","volume":"47","author":"Shi","year":"2013","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0290","doi-asserted-by":"crossref","first-page":"75417","DOI":"10.1007\/s11356-023-27552-7","article-title":"Urbanization led to the abundance of gram-negative, chemo-organo-heterotrophs, and antibiotic resistance genes in the downstream regions of the Ganga River water of India","volume":"30","author":"Srivastava","year":"2023","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0295","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.scitotenv.2018.11.211","article-title":"Distribution of clinically relevant antibiotic resistance genes in Lake tai","volume":"655","author":"Stange","year":"2019","journal-title":"China. Sci. Total Environ."},{"issue":"19\u201320","key":"10.1016\/j.scitotenv.2024.170788_bb0300","doi-asserted-by":"crossref","first-page":"6785","DOI":"10.1007\/s00253-022-12162-z","article-title":"Dynamic distribution and potential transmission of antibiotic resistance genes in activated sludge","volume":"106","author":"Tian","year":"2022","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122110","article-title":"Occurrence, distribution, and source track of antibiotics and antibiotic resistance genes in the main rivers of Chongqing city, Southwest China","volume":"389","author":"Wang","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.159913","article-title":"Metagenomic analysis revealed sources, transmission, and health risk of antibiotic resistance genes in confluence of Fenhe, Weihe, and yellow Rivers","volume":"858","author":"Wang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122426","article-title":"Distribution of antibiotic resistance genes in an agriculturally disturbed lake in China: their links with microbial communities, antibiotics, and water quality","volume":"393","author":"Wang","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.157472","article-title":"Antibiotic resistance genes in Chishui River, a tributary of the Yangtze River, China: occurrence, seasonal variation and its relationships with antibiotics, heavy metals and microbial communities","volume":"846","author":"Wu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.156536","article-title":"Antibiotic resistome and its driving factors in an urban river in northern China","volume":"838","author":"Wu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0335","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.envpol.2016.02.013","article-title":"High-throughput profiling of antibiotic resistance genes in drinking water treatment plants and distribution systems","volume":"213","author":"Xu","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0340","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.scitotenv.2018.03.085","article-title":"Tetracyclines, sulfonamides and quinolones and their corresponding resistance genes in the three gorges reservoir","volume":"631","author":"Yan","year":"2018","journal-title":"China. Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.scitotenv.2024.170788_bb0345","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1021\/acs.est.1c04250","article-title":"Which micropollutants in water environments deserve more attention globally","volume":"56","author":"Yang","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118304","article-title":"Seasonal distribution of antibiotic resistance genes in the Yellow River water and tap water, and their potential transmission from water to human","volume":"292","author":"Yu","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0355","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116455","article-title":"Antibiotics and antibiotic resistant genes (ARGs) in groundwater: a global review on dissemination, sources, interactions, environmental and human health risks","volume":"187","author":"Zainab","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2021.117507","article-title":"Distribution of antibiotic resistance genes in Karst River and its ecological risk","volume":"203","author":"Zhang","year":"2021","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0365","article-title":"Metagenomic survey reveals more diverse and abundant antibiotic resistance genes in municipal wastewater than hospital wastewater","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.147873","article-title":"River restoration changes distributions of antibiotics, antibiotic resistance genes, and microbial community","volume":"788","author":"Zhang","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0375","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.158530","article-title":"The antibiotic resistance and risk heterogeneity between urban and rural rivers in a pharmaceutical industry dominated city in China: the importance of social-economic factors","volume":"852","author":"Zhang","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0380","doi-asserted-by":"crossref","first-page":"21467","DOI":"10.1007\/s11356-018-2507-z","article-title":"Antibiotic resistance genes in China: occurrence, risk, and correlation among different parameters","volume":"25","author":"Zhao","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0385","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.envpol.2017.07.025","article-title":"High-throughput profiling and analysis of antibiotic resistance genes in east Tiaoxi River","volume":"230","author":"Zheng","year":"2017","journal-title":"China. Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.152263","article-title":"Metagenomic profiles of the resistome in subtropical estuaries: co-occurrence patterns, indicative genes, and driving factors","volume":"810","author":"Zhou","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"9","key":"10.1016\/j.scitotenv.2024.170788_bb0395","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1073\/pnas.1222743110","article-title":"Diverse and abundant antibiotic resistance genes in Chinese swine farms","volume":"110","author":"Zhu","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2024.170788_bb0400","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117402","article-title":"Distribution of antibiotic resistance genes in the environment","volume":"285","author":"Zhuang","year":"2021","journal-title":"Environ. Pollut."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969724009276?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969724009276?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T08:40:55Z","timestamp":1787560855000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969724009276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":75,"alternative-id":["S0048969724009276"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.170788","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antibiotic resistance genes and mobile genetic elements in different rivers: The link with antibiotics, microbial communities, and human activities","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.170788","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"170788"}}