{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:18:05Z","timestamp":1792199885004,"version":"4.4.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.scitotenv.2024.172512","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T12:56:49Z","timestamp":1713272209000},"page":"172512","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["Exposure to volatile organic compounds and mortality in US adults: A population-based prospective cohort study"],"prefix":"10.1016","volume":"928","author":[{"given":"Xiaobing","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingrong","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunxiang","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruyi","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2024.172512_bb0005","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.aca.2012.04.009","article-title":"Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI\/MSMS)","volume":"750","author":"Alwis","year":"2012","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0010","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1080\/03601234.2019.1634418","article-title":"Acrylamide-induced alterations in lungs of mice in relation to oxidative stress indicators","volume":"54","author":"Batoryna","year":"2019","journal-title":"J. Environ. Sci. Health B"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0015","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.bbadis.2016.11.010","article-title":"Mitochondrial dysfunction and oxidative stress in metabolic disorders - a step towards mitochondria based therapeutic strategies","volume":"1863","author":"Bhatti","year":"2017","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jenvman.2016.03.051","article-title":"The modifying effect of socioeconomic status on the relationship between traffic, air pollution and respiratory health in elementary schoolchildren","volume":"177","author":"Cakmak","year":"2016","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0025","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.amjmed.2006.05.056","article-title":"Effects of socioeconomic status on mortality after acute myocardial infarction","volume":"120","author":"Chang","year":"2007","journal-title":"Am. J. Med."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0030","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.scitotenv.2017.09.046","article-title":"Prenatal TVOCs exposure negatively influences postnatal neurobehavioral development","volume":"618","author":"Chang","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0035","article-title":"Weight change across adulthood in relation to all cause and cause specific mortality: prospective cohort study","volume":"367","author":"Chen","year":"2019","journal-title":"Br. Med. J."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.138650","article-title":"Exposure to phenols, chlorophenol pesticides, phthalate and PAHs and mortality risk: a prospective study based on 6 rounds of NHANES","volume":"329","author":"Di","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131791","article-title":"Urinary acrolein metabolites, systemic inflammation, and blood lipids: results from the National Health and Nutrition Examination Survey","volume":"286","author":"Feng","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0050","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/s41573-021-00233-1","article-title":"Targeting oxidative stress in disease: promise and limitations of antioxidant therapy","volume":"20","author":"Forman","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0055","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.tox.2017.01.005","article-title":"1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice","volume":"378","author":"Hartman","year":"2017","journal-title":"Toxicology"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0060","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1111\/ina.12602","article-title":"Human respiratory system as sink for volatile organic compounds: evidence from field measurements","volume":"29","author":"He","year":"2019","journal-title":"Indoor Air"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0120023","article-title":"Elevated levels of mercapturic acids of acrolein and crotonaldehyde in the urine of Chinese women in Singapore who regularly cook at home","volume":"10","author":"Hecht","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0070","doi-asserted-by":"crossref","DOI":"10.1289\/EHP5838","article-title":"A quantile-based g-computation approach to addressing the effects of exposure mixtures","volume":"128","author":"Keil","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0075","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.envpol.2019.03.086","article-title":"Occupational exposure to volatile organic compounds and health risks in Colorado nail salons","volume":"249","author":"Lamplugh","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.137738","article-title":"The association analysis between exposure to volatile organic chemicals and obesity in the general USA population: a cross-sectional study from NHANES program","volume":"315","author":"Lei","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0085","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.22190","article-title":"Study on the potential way of hepatic cytotoxicity of N,N-dimethylformamide","volume":"32","author":"Li","year":"2018","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0090","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.enceco.2021.01.001","article-title":"A review of environmental occurrence, toxicity, biotransformation and biomonitoring of volatile organic compounds","volume":"3","author":"Li","year":"2021","journal-title":"Environ. Chem. Ecotoxicol."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131590","article-title":"Blood volatile organic aromatic compounds concentrations across adulthood in relation to total and cause specific mortality: a prospective cohort study","volume":"286","author":"Li","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0100","doi-asserted-by":"crossref","first-page":"153705","DOI":"10.1016\/j.tox.2023.153705","article-title":"Exposure to volatile organic compounds induces cardiovascular toxicity that may involve DNA methylation","volume":"501","author":"Li","year":"2023","journal-title":"Toxicology"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122745","article-title":"The association between urinary levels of 1,3-butadiene metabolites, cardiovascular risk factors, microparticles, and oxidative stress products in adolescents and young adults","volume":"396","author":"Lin","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0110","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1289\/ehp.11861","article-title":"Characterization of the chronic risk and hazard of hazardous air pollutants in the United States using ambient monitoring data","volume":"117","author":"McCarthy","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.110903","article-title":"Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated with vascular dysfunction","volume":"196","author":"McGraw","year":"2021","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.115384","article-title":"Exposure to volatile organic compounds is associated with hypertension in black adults: the Jackson heart study","volume":"223","author":"McGraw","year":"2023","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2022.107053","article-title":"Urinary volatile organic compound metabolites and reduced lung function in U.S. adults","volume":"205","author":"Mendy","year":"2022","journal-title":"Respir. Med."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0130","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/s41598-023-27474-x","article-title":"Family income and cardiovascular disease risk in American adults","volume":"13","author":"Minhas","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0135","author":"National Center for Health Statistics"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0140","author":"National Center for Health Statistics"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0145","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph192315599","article-title":"Exposure to crude oil-related volatile organic compounds associated with lung function decline in a longitudinal panel of children","volume":"19","author":"Noh","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.151704","article-title":"Diurnal variability in urinary volatile organic compound metabolites and its association with oxidative stress biomarkers","volume":"818","author":"Pal","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0155","doi-asserted-by":"crossref","first-page":"5463","DOI":"10.1007\/s00216-015-8719-x","article-title":"Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS\/MS methods","volume":"407","author":"Pluym","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0160","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.envint.2018.04.049","article-title":"Short-term effects of ambient benzene and TEX (toluene, ethylbenzene, and xylene combined) on cardiorespiratory mortality in Hong Kong","volume":"117","author":"Ran","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0165","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s00204-015-1494-9","article-title":"Monitoring urinary mercapturic acids as biomarkers of human dietary exposure to acrylamide in combination with acrylamide uptake assessment based on duplicate diets","volume":"90","author":"Ruenz","year":"2016","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0170","author":"U.S. Department of Health and Human Services"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0175","author":"United States Environmental Protection Agency"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0180","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.envpol.2012.12.022","article-title":"A cohort study of intra-urban variations in volatile organic compounds and mortality, Toronto, Canada","volume":"183","author":"Villeneuve","year":"2013","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0185","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1093\/aje\/kwt289","article-title":"A case-control study of long-term exposure to ambient volatile organic compounds and lung cancer in Toronto, Ontario, Canada","volume":"179","author":"Villeneuve","year":"2014","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0190","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1093\/toxsci\/kfab119","article-title":"Associations between residential exposure to volatile organic compounds and liver injury markers","volume":"185","author":"Wahlang","year":"2021","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.138604","article-title":"Association of urinary dimethylformamide metabolite with lung function decline: the potential mediating role of systematic inflammation estimated by C-reactive protein","volume":"726","author":"Wang","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146304","article-title":"Acrylamide exposure and pulmonary function reduction in general population: the mediating effect of systemic inflammation","volume":"778","author":"Wang","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107401","article-title":"Cross-sectional and longitudinal associations of acrolein exposure with pulmonary function alteration: assessing the potential roles of oxidative DNA damage, inflammation, and pulmonary epithelium injury in a general adult population","volume":"167","author":"Wang","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0210","doi-asserted-by":"crossref","first-page":"7162","DOI":"10.1021\/acs.est.2c09299","article-title":"Acrolein exposure impaired glucose homeostasis and increased risk of type 2 diabetes: an urban adult population-based cohort study with repeated measures","volume":"57","author":"Wang","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115412","article-title":"Association between urinary metabolites of volatile organic compounds and cardiovascular disease in the general population from NHANES 2011\u20132018","volume":"264","author":"Wang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0220","doi-asserted-by":"crossref","DOI":"10.1289\/EHP10393","article-title":"Exposure to per- and polyfluoroalkyl substances and mortality in U.S. adults: a population-based cohort study","volume":"130","author":"Wen","year":"2022","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0225","author":"World Health Organization"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0230","author":"World Health Organization. Office of Occupational Health"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111166","article-title":"Integration of proteomics, lipidomics, and metabolomics reveals novel metabolic mechanisms underlying N, N-dimethylformamide induced hepatotoxicity","volume":"205","author":"Xu","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0240","article-title":"Multiple imputation using SAS software","volume":"45","author":"Yang Yuan","year":"2011","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0245","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1001\/jamapsychiatry.2022.4812","article-title":"Long-term exposure to multiple ambient air pollutants and association with incident depression and anxiety","volume":"80","author":"Yang","year":"2023","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.scitotenv.2024.172512_bb0250","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.2147\/COPD.S208633","article-title":"The relationship between acrolein and oxidative stress in COPD: in systemic plasma and in local lung tissue","volume":"14","author":"Yasuo","year":"2019","journal-title":"Int. J. Chron. Obstruct. Pulmon. Dis."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0255","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1021\/acs.estlett.2c00944","article-title":"Trends of full-volatility organic emissions in China from 2005 to 2019 and their organic aerosol formation potentials","volume":"10","author":"Zheng","year":"2023","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2024.172512_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.137489","article-title":"Environmental and human health impacts of volatile organic compounds: a perspective review","volume":"313","author":"Zhou","year":"2023","journal-title":"Chemosphere"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969724026585?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969724026585?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T17:32:02Z","timestamp":1785432722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969724026585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":52,"alternative-id":["S0048969724026585"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.172512","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exposure to volatile organic compounds and mortality in US adults: A population-based prospective cohort study","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.172512","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"172512"}}