{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T17:42:28Z","timestamp":1786210948778,"version":"build-2736575974"},"reference-count":118,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019464","name":"Leibniz-Zentrum fur Marine Tropenforschung GmbH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019464","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023174","name":"Kementerian Pendidikan, Kebudayaan, Riset, dan Teknologi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023174","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005980","name":"Ministry of Education Culture Research and Technology","doi-asserted-by":"publisher","award":["L3749-INO"],"award-info":[{"award-number":["L3749-INO"]}],"id":[{"id":"10.13039\/501100005980","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.scitotenv.2024.173000","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T01:58:07Z","timestamp":1714960687000},"page":"173000","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Simultaneous ocean acidification and warming do not alter the lipid-associated biochemistry but induce enzyme activities in an asterinid starfish"],"prefix":"10.1016","volume":"932","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8264-5317","authenticated-orcid":false,"given":"Munawar","family":"Khalil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9155-9464","authenticated-orcid":false,"given":"Marleen","family":"Stuhr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9500-4332","authenticated-orcid":false,"given":"Andreas","family":"Kunzmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7324-6122","authenticated-orcid":false,"given":"Hildegard","family":"Westphal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2024.173000_bb0005","article-title":"Ocean acidification and warming effects on the physiology, skeletal properties, and microbiome of the purple-hinge rock scallop","volume":"240","author":"Alma","year":"2020","journal-title":"Comp. Biochem. Physiol. Part A Mol. Integr. Physiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0010","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s00394-009-0057-3","article-title":"Effect of polyunsaturated fatty acids on the reactive oxygen and nitrogen species production by raw 264.7 macrophages","volume":"49","author":"Ambrozova","year":"2010","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0015","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.foodres.2014.07.023","article-title":"Effect of warming on protein, glycogen and fatty acid content of native and invasive clams","volume":"64","author":"Anacleto","year":"2014","journal-title":"Food Res. Int."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2023.115956","article-title":"Skeletal Mg content in common echinoderm species from deception and Livingston Islands (South Shetland Islands, Antarctica) in the context of global change","volume":"199","author":"Azcarate-Garcia","year":"2024","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0025","doi-asserted-by":"crossref","first-page":"3130","DOI":"10.1111\/gcb.14116","article-title":"Elucidating the sponge stress response; lipids and fatty acids can facilitate survival under future climate scenarios","volume":"24","author":"Bennett","year":"2018","journal-title":"Glob. Chang. Biol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0030","series-title":"Enzyme Kinetics: Principles and Methods","author":"Bisswanger","year":"2017"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0035","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/y59-099","article-title":"A rapid method of total lipid extraction and purification","volume":"37","author":"Bligh","year":"1959","journal-title":"Can. J. Biochem. Physiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0040","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0045","series-title":"Lipids in Aquatic Ecosystems","first-page":"115","article-title":"Crustacean zooplankton fatty acid composition","author":"Brett","year":"2009"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0050","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0305-0491(81)90237-6","article-title":"Characterization of Na+ + K+ -ATPase and Mg2+-ATPases from the gill and the kidney of the goldfish (Carassius auratus L.)","volume":"69","author":"Busacker","year":"1981","journal-title":"Comp. Biochem. Physiol. Part B Biochem. Mol. Biol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0055","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/plankt\/20.2.355","article-title":"The synergistic effect of carbon concentration and high temperature on lipid peroxidation in Peridinium gatunense","volume":"20","author":"Butow","year":"1998","journal-title":"J. Plankton Res."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0060","series-title":"Oceanography and Marine Biology: An Annual Review","first-page":"1","article-title":"Impact of ocean warming and ocean acidification on marine invertebrate life history stages: vulnerabilities and potential for persistence in a changing ocean","author":"Byrne","year":"2011"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0065","doi-asserted-by":"crossref","DOI":"10.1093\/conphys\/coz062","article-title":"The impact of environmental acidification on the microstructure and mechanical integrity of marine invertebrate skeletons","volume":"7","author":"Byrne","year":"2019","journal-title":"Conserv. Physiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0070","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3354\/meps10058","article-title":"Effects of ocean warming and acidification on embryos and non-calcifying larvae of the invasive sea star Patiriella regularis","volume":"473","author":"Byrne","year":"2013","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0075","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3390\/nu2030355","article-title":"Omega-3 fatty acids and inflammatory processes","volume":"2","author":"Calder","year":"2010","journal-title":"Nutrients"},{"issue":"Suppl. 3","key":"10.1016\/j.scitotenv.2024.173000_bb0080","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1038\/sj.ejcn.1601478","article-title":"Polyunsaturated fatty acids, inflammation and immunity","volume":"56","author":"Calder","year":"2002","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0085","doi-asserted-by":"crossref","first-page":"902","DOI":"10.3389\/fphys.2017.00902","article-title":"Palmitic acid: physiological role, metabolism and nutritional implications","volume":"8","author":"Carta","year":"2017","journal-title":"Front. Physiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0090","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0003-2697(86)90640-8","article-title":"A direct colorimetric assay for Ca2+-stimulated ATPase activity","volume":"157","author":"Chan","year":"1986","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0095","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1146\/annurev.ea.12.050184.001453","article-title":"Physics and chemistry of biomineralization","volume":"12","author":"Chave","year":"1984","journal-title":"Annu. Rev. Earth Planet. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0100","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s11745-998-0214-x","article-title":"Gas chromatography-mass spectrometry methods for structural analysis of fatty acids","volume":"33","author":"Christie","year":"1998","journal-title":"Lipids"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0105","series-title":"Advances in Marine Biology","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0065-2881(03)46005-7","article-title":"Fatty acid trophic markers in the pelagic marine environment","author":"Dalsgaard","year":"2003"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0110","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201700504","article-title":"Is palmitoleic acid a plausible nonpharmacological strategy to prevent or control chronic metabolic and inflammatory disorders?","volume":"62","author":"de Souza","year":"2018","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0115","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1126\/science.1075882","article-title":"Fossil echinoderms as monitor of the Mg\/Ca ratio of Phanerozoic oceans","volume":"298","author":"Dickson","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0120","series-title":"Guide to Best Practices for Ocean CO2 Measurements","volume":"vol. 3","year":"2007"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0125","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0300-9629(89)90784-6","article-title":"Na+, K+-ATPase, Mg2+-ATPase and Ca2+-ATPase activity during arm regeneration in the starfish Asterias forbesi","volume":"94","author":"Donachy","year":"1989","journal-title":"Comp. Biochem. Physiol. Part A Mol. Integr. Physiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0130","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1146\/annurev-marine-041911-111611","article-title":"Climate change impacts on marine ecosystems","volume":"4","author":"Doney","year":"2012","journal-title":"Ann. Rev. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0135","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1086\/BBLv226n3p223","article-title":"The skeleton of postmetamorphic echinoderms in a changing world","volume":"226","author":"Dubois","year":"2014","journal-title":"Biol. Bull."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0140","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1086\/716913","article-title":"Life-history analysis of asterinid starfishes","volume":"241","author":"Ebert","year":"2021","journal-title":"Biol. Bull."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0145","doi-asserted-by":"crossref","first-page":"4776","DOI":"10.1016\/j.jmb.2016.08.013","article-title":"Homeoviscous adaptation and the regulation of membrane lipids","volume":"428","author":"Ernst","year":"2016","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0150","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1126\/science.1097329","article-title":"Impact of anthropogenic CO2 on the CaCO3 system in the oceans","volume":"305","author":"Feely","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0155","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2021.584445","article-title":"A review and meta-analysis of potential impacts of ocean acidification on marine calcifiers from the Southern Ocean","volume":"8","author":"Figuerola","year":"2021","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0160","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.ecolind.2016.03.044","article-title":"Fatty acid profiling as bioindicator of chemical stress in marine organisms: a review","volume":"67","author":"Filimonova","year":"2016","journal-title":"Ecol. Indic."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0165","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0021-9258(18)84756-1","article-title":"The colorimetric determination of phosphorus","volume":"66","author":"Fiske","year":"1925","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0170","series-title":"An R Companion to Applied Regression","author":"Fox","year":"2019"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0129723","article-title":"A fatty acid based bayesian approach for inferring diet in aquatic consumers","volume":"10","author":"Galloway","year":"2015","journal-title":"PloS One"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0180","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.dci.2017.12.022","article-title":"The immune-related fatty acids are responsive to CO2 driven seawater acidification in a crustacean brine shrimp Artemia sinica","volume":"81","author":"Gao","year":"2018","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0185","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s42995-020-00048-w","article-title":"Impacts of ocean acidification under multiple stressors on typical organisms and ecological processes","volume":"2","author":"Gao","year":"2020","journal-title":"Mar. Life Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0190","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0155952","article-title":"Combined effects of ocean warming and acidification on copepod abundance, body size and fatty acid content","volume":"11","author":"Garzke","year":"2016","journal-title":"PloS One"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0195","doi-asserted-by":"crossref","first-page":"9316","DOI":"10.1073\/pnas.0811143106","article-title":"Elevated water temperature and carbon dioxide concentration increase the growth of a keystone echinoderm","volume":"106","author":"Gooding","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0200","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/s43017-022-00381-x","article-title":"Trends and variability in the ocean carbon sink","volume":"4","author":"Gruber","year":"2023","journal-title":"Nat. Rev. Earth Environ."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0205","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1196\/annals.1439.013","article-title":"Ocean acidification and its potential effects on marine ecosystems","volume":"1134","author":"Guinotte","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0210","series-title":"Lipid Biochemistry","author":"Gurr","year":"2002"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0215","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1461-0248.2005.00871.x","article-title":"The impacts of climate change in coastal marine systems","volume":"9","author":"Harley","year":"2006","journal-title":"Ecol. Lett."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0220","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1146\/annurev.ph.57.030195.000315","article-title":"Thermal adaptation in biological membranes: is homeoviscous adaptation the explanation?","volume":"57","author":"Hazel","year":"1995","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0225","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0163-7827(90)90002-3","article-title":"The role of alterations in membrane lipid composition in enabling physiological adaptation of organisms to their physical environment","volume":"29","author":"Hazel","year":"1990","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0230","series-title":"Animal Physiology","author":"Hill","year":"2012"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0235","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3354\/meps255193","article-title":"Feeding ecology of deep-sea seastars (Echinodermata: Asteroidea): a fatty-acid biomarker approach","volume":"255","author":"Howell","year":"2003","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154244","article-title":"Meta-analysis reveals variance in tolerance to climate change across marine trophic levels","volume":"827","author":"Hu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.jembe.2021.151685","article-title":"Impact of near-future ocean warming and acidification on the larval development of coral-eating starfish Acanthaster cf. solaris after parental exposure","volume":"548","author":"Hue","year":"2022","journal-title":"J. Exp. Mar. Biol. Ecol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0250","series-title":"The Fifth Assessment Report of the Intergovernmental Panel on Climate Change","first-page":"151","article-title":"Climate change 2014: Synthesis report. Contribution of working groups I, II and III to the fifth assessment report of the Intergovernmental Panel on Climate Change","author":"IPCC","year":"2014"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0255","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1432-1033.1977.tb11778.x","article-title":"IUPAC-IUB Commission on biochemical nomenclature (CBN). The nomenclature of lipids. Recommendations, 1976","volume":"79","author":"IUPAC-IUB","year":"1977","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0260","article-title":"Effects of seawater salinity and pH on cellular metabolism and enzyme activities in biomineralizing tissues of marine bivalves","volume":"248","author":"Ivanina","year":"2020","journal-title":"Comp. Biochem. Physiol. Part A Mol. Integr. Physiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0265","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.3389\/fphys.2018.01952","article-title":"Diurnally fluctuating pCO2 modifies the physiological responses of coral recruits under ocean acidification","volume":"9","author":"Jiang","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0270","series-title":"Lipids in Aquatic Ecosystems","first-page":"93","article-title":"Integrating lipids and contaminants in aquatic ecology and ecotoxicology","author":"Kainz","year":"2009"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0275","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1007\/s00338-016-1480-6","article-title":"Near-future ocean acidification enhances the feeding rate and development of the herbivorous juveniles of the crown-of-thorns starfish, Acanthaster planci","volume":"35","author":"Kamya","year":"2016","journal-title":"Coral Reefs"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0280","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1139\/f07-122","article-title":"Perspectives on marine zooplankton lipids","volume":"64","author":"Kattner","year":"2007","journal-title":"Can. J. Fish. Aquat. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0285","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.3390\/jmse10081065","article-title":"Ocean warming amplifies the effects of ocean acidification on skeletal mineralogy and microstructure in the asterinid starfish Aquilonastra yairi","volume":"10","author":"Khalil","year":"2022","journal-title":"J. Mar. Sci. Eng."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0290","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s00338-023-02388-2","article-title":"Long-term physiological responses to combined ocean acidification and warming show energetic trade-offs in an asterinid starfish","volume":"42","author":"Khalil","year":"2023","journal-title":"Coral Reefs"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0295","article-title":"Ca-ATPase and Mg-ATPase enzyme activities of the tropical-subtropical starfish Aquilonastra yairi under ocean acidification and warming in the laboratory","author":"Khalil","year":"2024","journal-title":"PANGAEA"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0300","article-title":"Fatty acid composition of the tropical-subtropical starfish Aquilonastra yairi under ocean acidification and warming in the laboratory","author":"Khalil","year":"2024","journal-title":"PANGAEA"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0305","article-title":"Total lipids of the tropical-subtropical starfish Aquilonastra yairi under ocean acidification and warming in the laboratory","author":"Khalil","year":"2024","journal-title":"PANGAEA"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0310","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/gbi.12409","article-title":"Effects of seawater Mg2+\/Ca2+ ratio and diet on the biomineralization and growth of sea urchins and the relevance of fossil echinoderms to paleoenvironmental reconstructions","volume":"18","author":"Kolbuk","year":"2020","journal-title":"Geobiology"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0315","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1111\/gcb.12179","article-title":"Impacts of ocean acidification on marine organisms: quantifying sensitivities and interaction with warming","volume":"19","author":"Kroeker","year":"2013","journal-title":"Glob. Chang. Biol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0320","doi-asserted-by":"crossref","DOI":"10.1002\/ece3.10307","article-title":"Impacts of ocean warming on echinoderms: a meta-analysis","volume":"13","author":"Lang","year":"2023","journal-title":"Ecol. Evol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0325","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/febs.12614","article-title":"Regulation of intracellular pH in cnidarians: response to acidosis in Anemonia viridis","volume":"281","author":"Laurent","year":"2014","journal-title":"FEBS J."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0330","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202107407","article-title":"Is ocean acidification really a threat to marine calcifiers? A systematic review and meta-analysis of 980+ studies spanning two decades","volume":"18","author":"Leung","year":"2022","journal-title":"Small"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0335","series-title":"Contributions to Probability and Statistics","first-page":"278","article-title":"Robust tests for equality of variances","author":"Levene","year":"1960"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0340","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2022.920163","article-title":"Membrane lipid sensitivity to ocean warming and acidification poses a severe threat to Arctic pteropods","volume":"9","author":"Lischka","year":"2022","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.marenvres.2022.105580","article-title":"Effects of ocean acidification and warming on the development and biochemical responses of juvenile shrimp Palaemon elegans (Rathke, 1837)","volume":"176","author":"Maia","year":"2022","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0350","doi-asserted-by":"crossref","first-page":"3366","DOI":"10.1002\/ece3.7289","article-title":"Temperature but not ocean acidification affects energy metabolism and enzyme activities in the blue mussel, Mytilus edulis","volume":"11","author":"Matoo","year":"2021","journal-title":"Ecol. Evol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0355","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1086\/BBLv223n3p312","article-title":"Development under elevated pCO2 conditions does not affect lipid utilization and protein content in early life-history stages of the purple sea urchin, Strongylocentrotus purpuratus","volume":"223","author":"Matson","year":"2012","journal-title":"Biol. Bull."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.jembe.2022.151779","article-title":"The effect of ocean acidification on the escape behaviour of the sea star Parvulastra exigua to its sea star predator Meridiastra calcar","volume":"555","author":"McLaren","year":"2022","journal-title":"J. Exp. Mar. Biol. Ecol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0365","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1146\/annurev-marine-010419-010658","article-title":"Ocean acidification and coastal marine invertebrates: tracking CO2 effects from seawater to the cell","volume":"12","author":"Melzner","year":"2020","journal-title":"Ann. Rev. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0370","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0163-7827(01)00013-3","article-title":"The biogenesis and functions of lipid bodies in animals, plants and microorganisms","volume":"40","author":"Murphy","year":"2001","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0375","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1146\/annurev.nutr.24.121803.063211","article-title":"Structure, function, and dietary regulation of \u03946, \u03945, and \u03949 desaturases","volume":"24","author":"Nakamura","year":"2004","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0380","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jembe.2013.12.007","article-title":"Early benthic juvenile Parvulastra exigua (Asteroidea) are tolerant to extreme acidification and warming in its intertidal habitat","volume":"453","author":"Nguyen","year":"2014","journal-title":"J. Exp. Mar. Biol. Ecol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0385","doi-asserted-by":"crossref","first-page":"257","DOI":"10.24199\/j.mmv.2006.63.18","article-title":"A systematic revision of the asterinid genus Aquilonastra O'Loughlin, 2004 (Echinodermata: Asteroidea)","volume":"63","author":"O'Loughlin","year":"2006","journal-title":"Mem. Mus. Vic."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0390","doi-asserted-by":"crossref","first-page":"4696","DOI":"10.1073\/pnas.1416967112","article-title":"Experimental ocean acidification alters the allocation of metabolic energy","volume":"112","author":"Pan","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0395","article-title":"Lipids in marine ecosystems","volume":"2013","author":"Parrish","year":"2013","journal-title":"Int. Sch. Res. Not."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0400","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3354\/meps12224","article-title":"Ocean acidification alters the burrowing behaviour, Ca2+\/Mg2+-ATPase activity, metabolism, and gene expression of a bivalve species, Sinonovacula constricta","volume":"575","author":"Peng","year":"2017","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0405","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2015.0418","article-title":"Calcium and ATP control multiple vital functions","volume":"371","author":"Petersen","year":"2016","journal-title":"Philos. Trans. R. Soc. Lond. B. Biol. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0410","doi-asserted-by":"crossref","first-page":"310","DOI":"10.32614\/RJ-2021-041","article-title":"Finding optimal normalizing transformations via bestNormalize","volume":"13","author":"Peterson","year":"2021","journal-title":"R. J."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0415","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3354\/meps07768","article-title":"Ecosystem effects of ocean acidification in times of ocean warming: a physiologist\u2019s view","volume":"373","author":"P\u00f6rtner","year":"2008","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0420","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/jeu.12325","article-title":"Effects of elevated temperature on the shell density of the large benthic foraminifera Amphistegina lobifera","volume":"63","author":"Prazeres","year":"2016","journal-title":"J. Eukaryot. Microbiol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0425","article-title":"Ocean acidification induces biochemical and morphological changes in the calcification process of large benthic foraminifera","volume":"282","author":"Prazeres","year":"2015","journal-title":"Proc. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0430","series-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2023"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0435","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1038\/s41467-017-01806-8","article-title":"Mussel larvae modify calcifying fluid carbonate chemistry to promote calcification","volume":"8","author":"Ramesh","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0440","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0034737","article-title":"Ocean acidification-induced food quality deterioration constrains trophic transfer","volume":"7","author":"Rossoll","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0445","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2021.715167","article-title":"Physiological response of shallow-water hard coral Acropora digitifera to heat stress via fatty acid composition","volume":"8","author":"Safuan","year":"2021","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0450","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/s41559-020-01370-3","article-title":"Impacts of hypoxic events surpass those of future ocean warming and acidification","volume":"5","author":"Sampaio","year":"2021","journal-title":"Nat. Ecol. Evol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0455","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1007\/s00227-012-2057-8","article-title":"Impact of ocean acidification on escape performance of the king scallop, Pecten maximus, from Norway","volume":"160","author":"Schalkhausser","year":"2012","journal-title":"Mar. Biol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0460","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.plipres.2007.12.004","article-title":"The opposing effects of n-3 and n-6 fatty acids","volume":"47","author":"Schmitz","year":"2008","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0465","doi-asserted-by":"crossref","DOI":"10.3390\/ani13071161","article-title":"Increased food resources help eastern oyster mitigate the negative impacts of coastal acidification","volume":"13","author":"Schwaner","year":"2023","journal-title":"Animals"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0470","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/biomet\/52.3-4.591","article-title":"An analysis of variance test for normality (complete samples)","volume":"52","author":"Shapiro","year":"1965","journal-title":"Biometrika"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0475","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1073\/pnas.71.2.522","article-title":"Homeoviscous adaptation\u2014a homeostatic process that regulates the viscosity of membrane lipids in Escherichia coli","volume":"71","author":"Sinensky","year":"1974","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0480","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/s41558-019-0412-1","article-title":"Marine heatwaves threaten global biodiversity and the provision of ecosystem services","volume":"9","author":"Smale","year":"2019","journal-title":"Nat. Clim. Chang."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0485","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3354\/meps11908","article-title":"Risk and resilience: variations in magnesium in echinoid skeletal calcite","volume":"561","author":"Smith","year":"2016","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0490","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.marenvres.2012.04.003","article-title":"Energy homeostasis as an integrative tool for assessing limits of environmental stress tolerance in aquatic invertebrates","volume":"79","author":"Sokolova","year":"2012","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0495","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.es.09.110178.000245","article-title":"Temperature adaptation of enzymes: biological optimization through structure-function compromises","volume":"9","author":"Somero","year":"1978","journal-title":"Annu. Rev. Ecol. Syst."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0500","doi-asserted-by":"crossref","first-page":"92","DOI":"10.2307\/1541865","article-title":"Physiological roles of prostaglandins and other eicosanoids in invertebrates","volume":"173","author":"Stanley-Samuelson","year":"1987","journal-title":"Biol. Bull."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0505","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1093\/icesjms\/fsv194","article-title":"Biochemical responses to ocean acidification contrast between tropical corals with high and low abundances at volcanic carbon dioxide seeps","volume":"73","author":"Strahl","year":"2016","journal-title":"ICES J. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0510","series-title":"Acid-Base Balance and Nitrogen Excretion in Invertebrates","first-page":"261","article-title":"pH regulation and excretion in echinoderms","author":"Stumpp","year":"2017"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0515","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1080\/713610925","article-title":"Metabolism and functions of lipids and fatty acids in teleost fish","volume":"11","author":"Tocher","year":"2010","journal-title":"Rev. Fish. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0520","article-title":"Threatened Caribbean coral is able to mitigate the adverse effects of ocean acidification on calcification by increasing feeding rate","volume":"10","author":"Towle","year":"2015","journal-title":"PloS One"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0525","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1242\/jeb.128389","article-title":"Novel and potential physiological roles of vacuolar-type H+-ATPase in marine organisms","volume":"219","author":"Tresguerres","year":"2016","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0530","doi-asserted-by":"crossref","first-page":"6019","DOI":"10.3390\/md13106019","article-title":"Ocean warming and CO2-induced acidification impact the lipid content of a marine predatory gastropod","volume":"13","author":"Valles-Regino","year":"2015","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0535","series-title":"Modern Applied Statistics with S","author":"Venables","year":"2002"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0540","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.chemosphere.2007.05.011","article-title":"Sublethal effect of silver and chromium in the green mussel Perna viridis with reference to alterations in oxygen uptake, filtration rate and membrane bound ATPase system as biomarkers","volume":"69","author":"Vijayavel","year":"2007","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0545","doi-asserted-by":"crossref","DOI":"10.3390\/fishes8010051","article-title":"Common sea star (Asterias rubens) coelomic fluid changes in response to short-term exposure to environmental stressors","volume":"8","author":"Wahltinez","year":"2023","journal-title":"Fishes"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0550","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.5194\/bg-6-2207-2009","article-title":"Impact of anthropogenic ocean acidification on thermal tolerance of the spider crab Hyas araneus","volume":"6","author":"Walther","year":"2009","journal-title":"Biogeosciences"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0555","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1745-7254.2007.00512.x","article-title":"Stearic acid protects primary cultured cortical neurons against oxidative stress","volume":"28","author":"Wang","year":"2007","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0560","doi-asserted-by":"crossref","first-page":"537","DOI":"10.2475\/ajs.267.5.537","article-title":"The incorporation of magnesium into the skeletal calcites of echinoderms","volume":"267","author":"Weber","year":"1969","journal-title":"Am. J. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0565","series-title":"ggplot2: Elegant Graphics for Data Analysis","author":"Wickham","year":"2016"},{"key":"10.1016\/j.scitotenv.2024.173000_bb0570","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2022.109449","article-title":"Effects of temperature and combinational exposures on lipid metabolism in aquatic invertebrates","volume":"262","author":"Yoon","year":"2022","journal-title":"Comp. Biochem. Physiol. Part C Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0575","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jtherbio.2016.07.011","article-title":"Impact of water temperature on the growth and fatty acid profiles of juvenile sea cucumber Apostichopus japonicus (Selenka)","volume":"60","author":"Yu","year":"2016","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0580","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1146\/annurev-earth-042711-105521","article-title":"History of seawater carbonate chemistry, atmospheric CO2, and ocean acidification","volume":"40","author":"Zeebe","year":"2012","journal-title":"Annu. Rev. Earth Planet. Sci."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0585","article-title":"Key enzymes in fatty acid synthesis pathway for bioactive lipids biosynthesis","volume":"9","author":"Zhuang","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.scitotenv.2024.173000_bb0590","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3390\/md21010021","article-title":"Fatty acids of echinoderms: diversity, current applications and future opportunities","volume":"21","author":"Zhukova","year":"2022","journal-title":"Mar. Drugs"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969724031474?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969724031474?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T16:44:02Z","timestamp":1786207442000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969724031474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":118,"alternative-id":["S0048969724031474"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.173000","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Simultaneous ocean acidification and warming do not alter the lipid-associated biochemistry but induce enzyme activities in an asterinid starfish","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.173000","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"173000"}}