{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:59:14Z","timestamp":1790927954700,"version":"4.1.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"NSFC","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.scitotenv.2024.174688","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T19:04:59Z","timestamp":1720551899000},"page":"174688","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Nanoplastics composite norfloxacin induced changes in conformation and function of lysozyme and differential effects of co-exposure contamination"],"prefix":"10.1016","volume":"947","author":[{"given":"Hengyu","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houquan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaifeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangxiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuqi","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuntao","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoyang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rutao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2024.174688_bb0005","doi-asserted-by":"crossref","first-page":"119749","DOI":"10.1016\/j.molliq.2022.119749","article-title":"Food additive dye\u2013lysozyme complexation: determination of binding constants and binding sites by fluorescence spectroscopy and modeling methods","volume":"363","author":"Asemi-Esfahani","year":"2022","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0010","doi-asserted-by":"crossref","first-page":"112402","DOI":"10.1016\/j.colsurfb.2022.112402","article-title":"The effect of putrescine on the lysozyme activity and structure: spectroscopic approaches and molecular dynamic simulation","volume":"213","author":"Ashrafi","year":"2022","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106367","article-title":"Interactions between microplastics, pharmaceuticals and personal care products: implications for vector transport","volume":"149","author":"Atugoda","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0020","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2200363119","article-title":"Dynamic intracellular exchange of nanomaterials\u2019 protein corona perturbs proteostasis and remodels cell metabolism","volume":"119","author":"Cai","year":"2022","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0025","doi-asserted-by":"crossref","first-page":"128176","DOI":"10.1016\/j.jhazmat.2021.128176","article-title":"Transcriptomic and metabolic responses of earthworms to contaminated soil with polypropylene and polyethylene microplastics at environmentally relevant concentrations","volume":"427","author":"Chen","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0030","doi-asserted-by":"crossref","first-page":"100937","DOI":"10.1016\/j.nantod.2020.100937","article-title":"Amyloidosis inhibition, a new frontier of the protein corona","volume":"35","author":"Chen","year":"2020","journal-title":"Nano Today"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0035","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.colsurfb.2016.12.030","article-title":"Effects of metal oxide nanoparticles on the structure and activity of lysozyme","volume":"151","author":"Cheng","year":"2017","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0040","doi-asserted-by":"crossref","first-page":"10262","DOI":"10.1021\/jf101417w","article-title":"Binding of oxytetracycline to bovine serum albumin: spectroscopic and molecular modeling investigations","volume":"58","author":"Chi","year":"2010","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0045","doi-asserted-by":"crossref","first-page":"115511","DOI":"10.1016\/j.molliq.2021.115511","article-title":"Evaluation of the binding of UFCB and Pb-UFCB to pepsin: spectroscopic analysis and enzyme activity assay","volume":"328","author":"Chu","year":"2021","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0050","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.envpol.2013.10.040","article-title":"Pharmaceuticals occurrence in a WWTP with significant industrial contribution and its input into the river system","volume":"185","author":"Collado","year":"2014","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0055","doi-asserted-by":"crossref","first-page":"114835","DOI":"10.1016\/j.molliq.2020.114835","article-title":"Interaction of reactive Red195 with human serum albumin: determination of the binding mechanism and binding site by spectroscopic and molecular modeling methods","volume":"327","author":"Farajzadeh-Dehkordi","year":"2021","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.polymdegradstab.2022.110239","article-title":"Kasuya K-i, Iwata T. Manufacture, physical properties, and degradation of biodegradable polyester microbeads","volume":"208","author":"Gan","year":"2023","journal-title":"Polym. Degrad. Stab."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0065","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.molliq.2019.04.134","article-title":"Probing the toxicity of long-chain fluorinated surfactants: interaction mechanism between perfluorodecanoic acid and lysozyme","volume":"285","author":"Gao","year":"2019","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0070","doi-asserted-by":"crossref","first-page":"167264","DOI":"10.1016\/j.scitotenv.2023.167264","article-title":"Environmental relevant concentrations of polystyrene nanoplastics and lead co-exposure triggered cellular cytotoxicity responses and underlying mechanisms in Eisenia fetida","volume":"905","author":"Guo","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0075","doi-asserted-by":"crossref","first-page":"169359","DOI":"10.1016\/j.scitotenv.2023.169359","article-title":"Novel evidence on iodoacetic acid-induced immune protein functional and conformational changes: focusing on cellular and molecular aspects","volume":"912","author":"Guo","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0080","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.cofs.2021.04.001","article-title":"Micro(nano)plastic contaminations from soils to plants: human food risks","volume":"41","author":"He","year":"2021","journal-title":"Curr. Opin. Food Sci."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0085","doi-asserted-by":"crossref","first-page":"116460","DOI":"10.1016\/j.molliq.2021.116460","article-title":"Binding interactions of acrylamide with lysozyme and its underlying mechanisms based on multi-spectra, isothermal titration microcalorimetry and docking simulation","volume":"337","author":"He","year":"2021","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0090","doi-asserted-by":"crossref","first-page":"126302","DOI":"10.1016\/j.jhazmat.2021.126302","article-title":"Toxic mechanism on phenanthrene-induced cytotoxicity, oxidative stress and activity changes of superoxide dismutase and catalase in earthworm (Eisenia foetida): a combined molecular and cellular study","volume":"418","author":"He","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0095","doi-asserted-by":"crossref","first-page":"153167","DOI":"10.1016\/j.scitotenv.2022.153167","article-title":"Toxic mechanism on phenanthrene-triggered cell apoptosis, genotoxicity, immunotoxicity and activity changes of immunity protein in Eisenia fetida: combined analysis at cellular and molecular levels","volume":"819","author":"He","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0100","doi-asserted-by":"crossref","first-page":"162854","DOI":"10.1016\/j.scitotenv.2023.162854","article-title":"Randomly-shaped nanoplastics induced stronger biotoxicity targeted to earthworm Eisenia fetida species: differential effects and the underlying mechanisms of realistic and commercial polystyrene nanoplastics","volume":"877","author":"He","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0105","doi-asserted-by":"crossref","first-page":"133032","DOI":"10.1016\/j.jhazmat.2023.133032","article-title":"Molecular mechanisms of nano-sized polystyrene plastics induced cytotoxicity and immunotoxicity in Eisenia fetida","volume":"465","author":"He","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0110","doi-asserted-by":"crossref","first-page":"133495","DOI":"10.1016\/j.jhazmat.2024.133495","article-title":"Regulation mechanisms of ferric ions release from iron-loaded transferrin protein caused by nano-sized polystyrene plastics-induced conformational and structural changes","volume":"465","author":"He","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0115","doi-asserted-by":"crossref","first-page":"133132","DOI":"10.1016\/j.jhazmat.2023.133132","article-title":"New mechanistic insights into halogen-dependent cytotoxic pattern of monohaloacetamide disinfection byproducts","volume":"465","author":"Hu","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0120","doi-asserted-by":"crossref","first-page":"121562","DOI":"10.1016\/j.watres.2024.121562","article-title":"Cytotoxicity of emerging halophenylacetamide disinfection byproducts in drinking water: mechanism and prediction","volume":"256","author":"Hu","year":"2024","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0125","doi-asserted-by":"crossref","first-page":"133801","DOI":"10.1016\/j.jhazmat.2024.133801","article-title":"Combined effects of norfloxacin and polystyrene nanoparticles on the oxidative stress and gut health of the juvenile horseshoe crab Tachypleus tridentatus","volume":"468","author":"Huang","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0130","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1073\/pnas.69.5.1151","article-title":"Fluorescence of lysozyme: emissions from tryptophan residues 62 and 108 and energy migration","volume":"69","author":"Imoto","year":"1972","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0135","doi-asserted-by":"crossref","first-page":"12514","DOI":"10.1039\/c3ra46053c","article-title":"Binding of alkaloids berberine, palmatine and coralyne to lysozyme: a combined structural and thermodynamic study","volume":"4","author":"Jash","year":"2014","journal-title":"RSC Adv."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0140","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.saa.2016.04.008","article-title":"Binding of copper to lysozyme: spectroscopic, isothermal titration calorimetry and molecular docking studies","volume":"164","author":"Jing","year":"2016","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0145","doi-asserted-by":"crossref","first-page":"118563","DOI":"10.1016\/j.molliq.2022.118563","article-title":"Cellular and molecular responses of earthworm coelomocytes and antioxidant enzymes to naphthalene and a major metabolite (1-naphthol)","volume":"350","author":"Jing","year":"2022","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0150","doi-asserted-by":"crossref","first-page":"107029","DOI":"10.1016\/j.bpc.2023.107029","article-title":"Mechanistic and biophysical insight into the inhibitory and disaggregase role of antibiotic moxifloxacin on human lysozyme amyloid formation","volume":"298","author":"Khan","year":"2023","journal-title":"Biophys. Chem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0155","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.molliq.2018.08.040","article-title":"Characterization of the binding of triprolidine hydrochloride to hen egg white lysozyme by multi-spectroscopic and molecular docking techniques","volume":"269","author":"Khatun","year":"2018","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0160","doi-asserted-by":"crossref","first-page":"3468","DOI":"10.1021\/es903490h","article-title":"Biodegradation and adsorption of antibiotics in the activated sludge process","volume":"44","author":"Li","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0165","doi-asserted-by":"crossref","first-page":"5462","DOI":"10.1039\/D2AN01552H","article-title":"Ultrasensitive detection of acephate based on carbon quantum dot-mediated fluorescence inner filter effects","volume":"147","author":"Li","year":"2022","journal-title":"Analyst"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0170","doi-asserted-by":"crossref","first-page":"127872","DOI":"10.1016\/j.jhazmat.2021.127872","article-title":"Molecular modeling of nanoplastic transformations in alveolar fluid and impacts on the lung surfactant film","volume":"427","author":"Li","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0175","doi-asserted-by":"crossref","DOI":"10.1002\/jmr.2874","article-title":"Study of the effects of ultrafine carbon black on the structure and function of trypsin","volume":"34","author":"Li","year":"2021","journal-title":"J. Mol. Recognit."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0180","doi-asserted-by":"crossref","first-page":"126781","DOI":"10.1016\/j.jhazmat.2021.126781","article-title":"Discrepancy of apoptotic events in mouse hepatocytes and catalase performance: size-dependent cellular and molecular toxicity of ultrafine carbon black","volume":"421","author":"Li","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0185","doi-asserted-by":"crossref","first-page":"120983","DOI":"10.1016\/j.saa.2022.120983","article-title":"The interaction mechanism between gold nanoparticles and proteins: lysozyme, trypsin, pepsin, \u03b3-globulin, and hemoglobin","volume":"272","author":"Li","year":"2022","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0190","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/j.1365-2389.2012.01459.x","article-title":"Influence of lysozyme complexation with purified Aldrich humic acid on lysozyme activity","volume":"63","author":"Li","year":"2012","journal-title":"Eur. J. Soil Sci."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0195","doi-asserted-by":"crossref","first-page":"129079","DOI":"10.1016\/j.chemosphere.2020.129079","article-title":"Hexabromocyclododecane alters malachite green and lead(II) adsorption behaviors onto polystyrene microplastics: interaction mechanism and competitive effect","volume":"265","author":"Lin","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0200","doi-asserted-by":"crossref","first-page":"132352","DOI":"10.1016\/j.jhazmat.2023.132352","article-title":"Multi-level biological effects of diverse alkyl chains phthalate esters on cotton seedlings (Gossypium hirsutum L.): insights into individual, physiological-biochemical and molecular perspectives","volume":"460","author":"Lv","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0205","doi-asserted-by":"crossref","first-page":"106277","DOI":"10.1016\/j.marenvres.2023.106277","article-title":"Combined toxic effects of nanoplastics and norfloxacin on antioxidant and immune genes in mussels","volume":"193","author":"Ma","year":"2024","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0210","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3390\/polym13020225","article-title":"Pyrolysis of polystyrene waste: a review","volume":"13","author":"Maafa","year":"2021","journal-title":"Polymers"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0215","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3390\/toxics10050270","article-title":"Nanoplastics: status and knowledge gaps in the finalization of environmental risk assessments","volume":"10","author":"Masseroni","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0220","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1039\/C5EM00227C","article-title":"Nano-plastics in the aquatic environment","volume":"17","author":"Mattsson","year":"2015","journal-title":"Environ Sci Process Impacts"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0225","doi-asserted-by":"crossref","first-page":"3218","DOI":"10.1021\/acsomega.9b03278","article-title":"Effect of agitation method on the Nanosized degradation of polystyrene microplastics dispersed in water","volume":"5","author":"Mekaru","year":"2020","journal-title":"ACS Omega"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0230","doi-asserted-by":"crossref","first-page":"4859","DOI":"10.1039\/C5CS00084J","article-title":"Circular dichroism spectroscopy of membrane proteins","volume":"45","author":"Miles","year":"2016","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0235","doi-asserted-by":"crossref","first-page":"113673","DOI":"10.1016\/j.colsurfb.2023.113673","article-title":"Adsorption of clarithromycin on polystyrene nanoplastics surface and its combined adverse effect on serum albumin","volume":"234","author":"Pani","year":"2024","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0240","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1432-1033.1969.tb00549.x","article-title":"X-ray analysis, structure and function of enzymes","volume":"8","author":"Perutz","year":"1969","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0245","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1038\/s41565-021-01056-2","article-title":"Nanoplastic versus natural organic matter","volume":"16","author":"Pulizzi","year":"2021","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0250","doi-asserted-by":"crossref","first-page":"3246","DOI":"10.1021\/jf200092y","article-title":"Perfluorodecanoic acid binding to hemoproteins: new insights from spectroscopic studies","volume":"59","author":"Qin","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0255","doi-asserted-by":"crossref","first-page":"4557","DOI":"10.1080\/07391102.2018.1553739","article-title":"Evaluation of maltose on conformation and activity parameters of trypsin","volume":"37","author":"Rajabi","year":"2019","journal-title":"J. Biomol. Struct. Dyn."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0260","doi-asserted-by":"crossref","first-page":"119081","DOI":"10.1016\/j.molliq.2022.119081","article-title":"Conformational binding mechanism of lysozyme induced by interactions with penicillin antibiotic drugs","volume":"358","author":"Rial","year":"2022","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0265","doi-asserted-by":"crossref","first-page":"7811","DOI":"10.1021\/acs.jpcb.8b03106","article-title":"Spectroscopic and molecular dynamics simulation study of lysozyme in the aqueous mixture of ethanol: insights into the nonmonotonic change of the structure of lysozyme","volume":"122","author":"Sarkar","year":"2018","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0270","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.jiec.2014.04.024","article-title":"Investigation the activity and stability of lysozyme on presence of magnetic nanoparticles","volume":"21","author":"Shareghi","year":"2015","journal-title":"J. Ind. Eng. Chem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0275","doi-asserted-by":"crossref","first-page":"10547","DOI":"10.1021\/acs.est.2c02778","article-title":"Eco-colloidal layer of micro\/nanoplastics increases complexity and uncertainty of their biotoxicity in aquatic environments","volume":"56","author":"Song","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0280","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1006\/abio.2000.4880","article-title":"Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set","volume":"287","author":"Sreerama","year":"2000","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0285","doi-asserted-by":"crossref","first-page":"117936","DOI":"10.1016\/j.envpol.2021.117936","article-title":"Probing the biological toxicity of pyrene to the earthworm Eisenia fetida and the toxicity pathways of oxidative damage: a systematic study at the animal and molecular levels","volume":"289","author":"Sun","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0290","doi-asserted-by":"crossref","first-page":"123151","DOI":"10.1016\/j.molliq.2023.123151","article-title":"Molecular toxicity of Cr(III) and Cr(VI) to defensive protein lysozyme and their differential mechanisms","volume":"390","author":"Tian","year":"2023","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0295","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","article-title":"AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading","volume":"31","author":"Trott","year":"2010","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0300","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1021\/la104124d","article-title":"Adsorption and conformation of serum albumin protein on gold nanoparticles investigated using dimensional measurements and in situ spectroscopic methods","volume":"27","author":"Tsai","year":"2011","journal-title":"Langmuir"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0305","doi-asserted-by":"crossref","first-page":"3738","DOI":"10.1039\/C5NJ02911B","article-title":"Probing the binding interaction between cadmium(ii) chloride and lysozyme","volume":"40","author":"Wang","year":"2016","journal-title":"New J. Chem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0310","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.desal.2015.05.010","article-title":"Performance of nanofiltration membrane in rejecting trace organic compounds: experiment and model prediction","volume":"370","author":"Wang","year":"2015","journal-title":"Desalination"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0315","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00726-008-0217-4","article-title":"Potential enzyme toxicity of perfluorooctanoic acid","volume":"38","author":"Wu","year":"2010","journal-title":"Amino Acids"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0320","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.saa.2015.06.080","article-title":"Probing the toxic mechanism of Ag+ with lysozyme","volume":"151","author":"Wu","year":"2015","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0325","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1021\/acs.jafc.9b07072","article-title":"Probing the cell apoptosis pathway induced by perfluorooctanoic acid and perfluorooctane sulfonate at the subcellular and molecular levels","volume":"68","author":"Xu","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0330","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.1016\/j.carbon.2007.09.010","article-title":"Particle size and zeta potential of carbon black in liquid media","volume":"45","author":"Xu","year":"2007","journal-title":"Carbon"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0335","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.163304","article-title":"Combined toxic effects of nanoplastics and norfloxacin on mussel: leveraging biochemical parameters and gut microbiota","volume":"880","author":"Xu","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0340","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph17082808","article-title":"The complex toxicity of tetracycline with polystyrene spheres on gastric cancer cells","volume":"17","author":"Yan","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.scitotenv.2024.174688_bb0345","doi-asserted-by":"crossref","first-page":"160903","DOI":"10.1016\/j.scitotenv.2022.160903","article-title":"Spectroscopic investigations on the interaction between nano plastic and catalase on molecular level","volume":"863","author":"Yao","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0350","doi-asserted-by":"crossref","first-page":"114347","DOI":"10.1016\/j.envpol.2020.114347","article-title":"Sorption of fluoroquinolones to nanoplastics as affected by surface functionalization and solution chemistry","volume":"262","author":"Zhang","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0355","doi-asserted-by":"crossref","first-page":"172511","DOI":"10.1016\/j.scitotenv.2024.172511","article-title":"Photochemically induced aging of polystyrene nanoplastics and its impact on norfloxacin adsorption behavior","volume":"930","author":"Zhang","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0360","doi-asserted-by":"crossref","first-page":"117537","DOI":"10.1016\/j.envpol.2021.117537","article-title":"Mechanistic insight into different adsorption of norfloxacin on microplastics in simulated natural water and real surface water","volume":"284","author":"Zhang","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0365","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.scitotenv.2009.11.014","article-title":"Residues of veterinary antibiotics in manures from feedlot livestock in eight provinces of China","volume":"408","author":"Zhao","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0370","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.21895","article-title":"Exploring the influence of MPA-capped CdTe quantum dots on the structure and function of lysozyme probing by spectroscopic and calorimetric methods","volume":"31","author":"Zhao","year":"2017","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.174688_bb0375","doi-asserted-by":"crossref","first-page":"133139","DOI":"10.1016\/j.chemosphere.2021.133139","article-title":"Comparison of the interactions of flupyrimin and nitenpyram with serum albumins via multiple analysis methods","volume":"289","author":"Zhao","year":"2022","journal-title":"Chemosphere"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896972404837X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004896972404837X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T20:57:46Z","timestamp":1787259466000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004896972404837X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":75,"alternative-id":["S004896972404837X"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.174688","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nanoplastics composite norfloxacin induced changes in conformation and function of lysozyme and differential effects of co-exposure contamination","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.174688","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"174688"}}