{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:45:38Z","timestamp":1788792338986,"version":"build-2803163510"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.scitotenv.2024.177835","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T12:10:52Z","timestamp":1733227852000},"page":"177835","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Potential impact of organophosphate esters on thyroid eye disease based on machine learning and molecular docking"],"prefix":"10.1016","volume":"957","author":[{"given":"Tianqi","family":"Jia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arturo A.","family":"Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lirong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baohui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinglin","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianao","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunci","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2024.177835_bb0005","doi-asserted-by":"crossref","first-page":"17762","DOI":"10.1021\/acs.est.2c04400","article-title":"Investigation of the binding fraction of PFAS in human plasma and underlying mechanisms based on machine learning and molecular dynamics simulation","volume":"57","author":"Cao","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0010","doi-asserted-by":"crossref","first-page":"6505","DOI":"10.1021\/acs.est.0c06117","article-title":"Designing QSARs for parameters of high-throughput toxicokinetic models using open-source descriptors","volume":"55","author":"Dawson","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2022.116601","article-title":"A review on organophosphate esters: physiochemical properties, applications, and toxicities as well as occurrence and human exposure in dust environment","volume":"325","author":"Dou","year":"2023","journal-title":"J. Environ. Manage."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0020","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.aquatox.2015.01.027","article-title":"Aryl organophosphate flame retardants induced cardiotoxicity during zebrafish embryogenesis: by disturbing expression of the transcriptional regulators","volume":"161","author":"Du","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0025","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1038\/s41586-022-05173-3","article-title":"Hormone- and antibody-mediated activation of the thyrotropin receptor","volume":"609","author":"Duan","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0030","doi-asserted-by":"crossref","first-page":"10192","DOI":"10.1021\/acs.est.0c08822","article-title":"Long-range transport, trophic transfer, and ecological risks of organophosphate esters in remote areas","volume":"55","author":"Fu","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0035","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.chemolab.2006.01.007","article-title":"Recursive feature elimination with random forest for PTR-MS analysis of agroindustrial products","volume":"83","author":"Granitto","year":"2006","journal-title":"Chemom. Intel. Lab. Syst."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.156300","article-title":"Thyroid-disrupting effects caused by exposure to alternative flame retardants from groundwater contamination in rural central China","volume":"839","author":"Han","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.133443","article-title":"NeuTox: a weighted ensemble model for screening potential neuronal cytotoxicity of chemicals based on various types of molecular representations","volume":"465","author":"He","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105698","article-title":"Organophosphate esters and their metabolites in paired human whole blood, serum, and urine as biomarkers of exposure","volume":"139","author":"Hou","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106803","article-title":"Exposure to organophosphate esters in elderly people: relationships of OPE body burdens with indoor air and dust concentrations and food consumption","volume":"157","author":"Hou","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0060","doi-asserted-by":"crossref","first-page":"8221","DOI":"10.1021\/acs.est.2c01850","article-title":"Penetration of organophosphate triesters and diesters across the blood-cerebrospinal fluid barrier: efficiencies, impact factors, and mechanisms","volume":"56","author":"Hou","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0065","doi-asserted-by":"crossref","first-page":"10425","DOI":"10.1038\/ncomms10425","article-title":"Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization","volume":"7","author":"Huang","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0070","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s00128-021-03454-7","article-title":"Industrial production of organophosphate flame retardants (OPFRs): big knowledge gaps need to be filled?","volume":"108","author":"Huang","year":"2022","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0075","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s13721-021-00326-2","article-title":"A machine learning regression model for the screening and design of potential SARS-CoV-2 protease inhibitors","volume":"10","author":"Janairo","year":"2021","journal-title":"Netw Model Anal Health Inform Bioinform"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0080","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1021\/acsestair.4c00042","article-title":"Assessing the risk of organophosphate esters from nail polish: indoor emissions, fate modeling, and health risk assessment","volume":"1","author":"Jia","year":"2024","journal-title":"ACS ES&T Air"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0085","first-page":"12","article-title":"Could graph neural networks learn better molecular representation for drug discovery? A comparison study of descriptor-based and graph-based models","volume":"13","author":"Jiang","year":"2021","journal-title":"J. Chem."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2020.104768","article-title":"Application of QSARs in identification of mutagenicity mechanisms of nitro and amino aromatic compounds against Salmonella typhimurium species","volume":"65","author":"Jillella","year":"2020","journal-title":"Toxicol. In Vitro"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.170173","article-title":"Towards safer pesticide management: a quantitative structure-activity relationship based hazard prediction model","volume":"916","author":"Karaduman","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0100","doi-asserted-by":"crossref","first-page":"13374","DOI":"10.1021\/acsomega.8b01834","article-title":"QSPR modeling of the refractive index for diverse polymers using 2D descriptors","volume":"3","author":"Khan","year":"2018","journal-title":"ACS Omega"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0105","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.aquatox.2015.01.016","article-title":"Thyroid disruption by triphenyl phosphate, an organophosphate flame retardant, in zebrafish (Danio rerio) embryos\/larvae, and in GH3 and FRTL-5 cell lines","volume":"160","author":"Kim","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113810","article-title":"Occurrence and ecological implications of organophosphate triesters and diester degradation products in wastewater, river water, and tap water","volume":"259","author":"Li","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.142757","article-title":"Organophosphorus pesticides in greenhouse and open-field soils across China: distribution characteristic, polluted pathway and health risk","volume":"765","author":"Li","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130153","article-title":"Occurrence, spatiotemporal variation, and ecological risks of organophosphate esters in the water and sediment of the middle and lower streams of the Yellow River and its important tributaries","volume":"443","author":"Li","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121941","article-title":"Organophosphate esters concentrations in human serum and their associations with Sjogren syndrome","volume":"331","author":"Liao","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0130","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1002\/etc.3395","article-title":"Long-term exposure to triphenylphosphate alters hormone balance and HPG, HPI, and HPT gene expression in zebrafish (Danio rerio)","volume":"35","author":"Liu","year":"2016","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0135","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ecoenv.2018.11.058","article-title":"Effects of tris(1,3-dichloro-2-propyl) phosphate (TDCPP) and triphenyl phosphate (TPP) on sex-dependent alterations of thyroid hormones in adult zebrafish","volume":"170","author":"Liu","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0140","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/s41586-021-04134-6","article-title":"Uncovering global-scale risks from commercial chemicals in air","volume":"600","author":"Liu","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0145","doi-asserted-by":"crossref","first-page":"17825","DOI":"10.1021\/acs.est.2c04759","article-title":"Exposure to novel brominated flame retardants and organophosphate esters and associations with thyroid cancer risk: a case-control study in eastern China","volume":"56","author":"Liu","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0150","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/ame2.12215","article-title":"Effects of long-term exposure to TDCPP in zebrafish (Danio rerio) - alternations of hormone balance and gene transcriptions along hypothalamus-pituitary axes","volume":"5","author":"Liu","year":"2022","journal-title":"Animal Model Exp Med"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124754","article-title":"Trimester-specific effects of maternal exposure to organophosphate flame retardants on offspring size at birth: a prospective cohort study in China","volume":"406","author":"Luo","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0160","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1016\/j.chemosphere.2015.10.049","article-title":"Effects of tris (2-butoxyethyl) phosphate (TBOEP) on endocrine axes during development of early life stages of zebrafish (Danio rerio)","volume":"144","author":"Ma","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0165","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1002\/jcc.21256","article-title":"AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility","volume":"30","author":"Morris","year":"2009","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0170","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1021\/acs.estlett.1c00210","article-title":"Early life exposure to tris(2-butoxyethyl) phosphate (TBOEP) is related to the development of childhood asthma","volume":"8","author":"Navaranjan","year":"2021","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.145105","article-title":"Organophosphate esters in airborne particles from subway stations","volume":"769","author":"Olivero-Verbel","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0180","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1021\/acs.jcim.3c00231","article-title":"Temperature-dependent density and viscosity prediction for hydrocarbons: machine learning and molecular dynamics simulations","volume":"64","author":"Panwar","year":"2024","journal-title":"J. Chem. Inf."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0185","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.fct.2017.04.016","article-title":"Development of human biotransformation QSARs and application for PBT assessment refinement","volume":"112","author":"Papa","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0190","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.fct.2017.10.044","article-title":"Modeling of adipose\/blood partition coefficient for environmental chemicals","volume":"110","author":"Papadaki","year":"2017","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0195","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ajo.2019.07.021","article-title":"A new era in the treatment of thyroid eye disease","volume":"208","author":"Patel","year":"2019","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0200","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1039\/D0CE00070A","article-title":"Machine learning methods to predict the crystallization propensity of small organic molecules","volume":"22","author":"Pereira","year":"2020","journal-title":"CrystEngComm"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0205","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.envint.2017.01.020","article-title":"Associations between urinary diphenyl phosphate and thyroid function","volume":"101","author":"Preston","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0210","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jes.2015.12.021","article-title":"In vitro assessment of thyroid hormone receptor activity of four organophosphate esters","volume":"45","author":"Ren","year":"2016","journal-title":"J. Environ. Sci. (China)"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0215","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.aquatox.2019.02.004","article-title":"Parental exposure to tris(1,3-dichloro-2-propyl) phosphate results in thyroid endocrine disruption and inhibition of growth in zebrafish offspring","volume":"209","author":"Ren","year":"2019","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0220","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/1062936031000073144","article-title":"E-state modeling of fish toxicity independent of 3D structure information","volume":"14","author":"Rose","year":"2003","journal-title":"SAR QSAR Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0225","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s40203-023-00167-z","article-title":"Discovery of new oxadiazolo pyridine derivatives as potent ghrelin O-acyltransferase inhibitors using molecular modeling techniques","volume":"11","author":"Sarkar","year":"2023","journal-title":"In Silico Pharmacol"},{"key":"10.1016\/j.scitotenv.2024.177835_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130248","article-title":"Handwipes as indicators to assess organophosphate flame retardants exposure and thyroid hormone effects in e-waste dismantlers","volume":"443","author":"Tang","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0235","doi-asserted-by":"crossref","first-page":"2124","DOI":"10.1021\/acs.est.8b05269","article-title":"Organohalogenated flame retardants and organophosphate esters in office air and dust from Sweden","volume":"53","author":"Tao","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0240","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.chemolab.2017.09.005","article-title":"ADME properties evaluation in drug discovery: prediction of plasma protein binding using NSGA-II combining PLS and consensus modeling","volume":"170","author":"Wang","year":"2017","journal-title":"Chemom. Intel. Lab. Syst."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2019.108982","article-title":"Computational evaluation of interactions between organophosphate esters and nuclear hormone receptors","volume":"182","author":"Wang","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0250","doi-asserted-by":"crossref","DOI":"10.1007\/s11249-023-01715-6","article-title":"Evaluating wear volume of oligoether esters with an interpretable machine learning approach","volume":"71","author":"Wang","year":"2023","journal-title":"Tribol. Lett."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0255","doi-asserted-by":"crossref","first-page":"5302","DOI":"10.1021\/acs.molpharmaceut.8b00785","article-title":"Predicting fraction unbound in human plasma from chemical structure: improved accuracy in the low value ranges","volume":"15","author":"Watanabe","year":"2018","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0260","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbaa321","article-title":"Do we need different machine learning algorithms for QSAR modeling? A comprehensive assessment of 16 machine learning algorithms on 14 QSAR data sets","volume":"22","author":"Wu","year":"2021","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127909","article-title":"Bioaccumulation and translocation of organophosphate esters in a Mangrove Nature Reserve from the Pearl River Estuary, South China","volume":"427","author":"Xie","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0270","doi-asserted-by":"crossref","first-page":"W5","DOI":"10.1093\/nar\/gkab255","article-title":"ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties","volume":"49","author":"Xiong","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.113175","article-title":"Application of machine learning to predict the inhibitory activity of organic chemicals on thyroid stimulating hormone receptor","volume":"212","author":"Xu","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.133650","article-title":"Determination of the binding affinities of OPEs to integrin alpha(v)beta(3) and elucidation of the underlying mechanisms via a competitive binding assay, pharmacophore modeling, molecular docking and QSAR modeling","volume":"466","author":"Xu","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105056","article-title":"Biomonitoring of organophosphate triesters and diesters in human blood in Jiangsu Province, eastern China: occurrences, associations, and suspect screening of novel metabolites","volume":"131","author":"Ya","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.112220","article-title":"Maternal urinary OPE metabolite concentrations and blood pressure during pregnancy: the HOME study","volume":"207","author":"Yang","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0295","doi-asserted-by":"crossref","first-page":"14668","DOI":"10.1021\/acs.est.2c04467","article-title":"Tox21-based comparative analyses for the identification of potential toxic effects of environmental pollutants","volume":"56","author":"Yang","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106215","article-title":"Exposure to organophosphate ester flame retardants and plasticizers during pregnancy: thyroid endocrine disruption and mediation role of oxidative stress","volume":"146","author":"Yao","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130080","article-title":"A global survey of organophosphate esters and their metabolites in milk: occurrence and dietary intake via milk consumption","volume":"442","author":"Yao","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0310","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1002\/jcc.21707","article-title":"PaDEL-descriptor: an open source software to calculate molecular descriptors and fingerprints","volume":"32","author":"Yap","year":"2011","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132095","article-title":"Established and emerging organophosphate esters (OPEs) and the expansion of an environmental contamination issue: a review and future directions","volume":"459","author":"Ye","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0320","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.envpol.2015.11.051","article-title":"Thyroid hormone-disrupting activity and ecological risk assessment of phosphorus-containing flame retardants by in vitro, in vivo and in silico approaches","volume":"210","author":"Zhang","year":"2016","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154271","article-title":"Organophosphate esters in agro-foods: occurrence, sources and emerging challenges","volume":"827","author":"Zhang","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130373","article-title":"Pollution profiles, influencing factors, and source apportionment of target and suspect organophosphate esters in ambient air: a case study in a typical city of Northern China","volume":"444","author":"Zhao","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2024.177835_bb0335","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.132407","article-title":"Experimental determination of octanol-water partition coefficient (K(OW)) of 39 liquid crystal monomers (LCMs) by use of the shake-flask method","volume":"287","author":"Zhu","year":"2022","journal-title":"Chemosphere"}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969724079920?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969724079920?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T09:33:59Z","timestamp":1737279239000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969724079920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":67,"alternative-id":["S0048969724079920"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.177835","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential impact of organophosphate esters on thyroid eye disease based on machine learning and molecular docking","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2024.177835","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"177835"}}