{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T02:52:14Z","timestamp":1775789534581,"version":"3.50.1"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"am","delay-in-days":346,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100007681","name":"Florida International University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007681","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DEB-2025954"],"award-info":[{"award-number":["DEB-2025954"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["HRD-1547798"],"award-info":[{"award-number":["HRD-1547798"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["HRD-2111661"],"award-info":[{"award-number":["HRD-2111661"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013992","name":"Bonefish & Tarpon Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013992","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Science of The Total Environment"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.scitotenv.2025.179106","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T10:16:10Z","timestamp":1741860970000},"page":"179106","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Occurrence of pharmaceuticals in muscle tissue of red drum (Sciaenops ocellatus) across subtropical estuaries: Comparison to blood plasma and implications for human exposure"],"prefix":"10.1016","volume":"972","author":[{"given":"W. Ryan","family":"James","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas A.","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andy","family":"Distrubell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shakira","family":"Trabelsi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolando O.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Cerveny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan J.","family":"Rezek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ross E.","family":"Boucek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron J.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerker","family":"Fick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomas","family":"Brodin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer S.","family":"Rehage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.scitotenv.2025.179106_bb0005","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.marpolbul.2004.10.049","article-title":"Mercury concentrations in red drum, Sciaenops ocellatus, from estuarine and offshore waters of Florida","volume":"50","author":"Adams","year":"2005","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127284","article-title":"Abundance, fate, and effects of pharmaceuticals and personal care products in aquatic environments","volume":"424","author":"Adeleye","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0015","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1890\/13-1452.1","article-title":"Model selection for ecologists: the worldviews of AIC and BIC","volume":"95","author":"Aho","year":"2014","journal-title":"Ecology"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0020","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.scitotenv.2014.04.112","article-title":"Pharmaceuticals and personal care products in chicken meat and other food animal products: a market-basket pilot study","volume":"490","author":"Baron","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.153635","article-title":"Fate and transport of pharmaceuticals in water systems: a processes review","volume":"823","author":"Bavumiragira","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0030","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.3390\/molecules26051229","article-title":"Determination of pharmaceuticals, heavy metals, and oxysterols in fish muscle","volume":"26","author":"Bobrowska-Korczak","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0035","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.envpol.2016.10.106","article-title":"Investigation and risk evaluation of the occurrence of carbamazepine, oxcarbazepine, their human metabolites and transformation products in the urban water cycle","volume":"225","author":"Brezina","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0040","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1126\/science.1226850","article-title":"Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations","volume":"339","author":"Brodin","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0045","article-title":"Towards precision ecotoxicology: leveraging evolutionary conservation of pharmaceutical and personal care product targets to understand adverse outcomes across species and life stages","volume":"1\u201311","author":"Brooks","year":"2023","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0050","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.chemosphere.2016.09.078","article-title":"Pay attention to non-wastewater emission pathways of pharmaceuticals into environments","volume":"165","author":"Bu","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135382","article-title":"Identifying pathways of pharmaceutical exposure in a mesoconsumer marine fish","volume":"477","author":"Castillo","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.140949","article-title":"Understanding pharmaceutical exposure and the potential for effects in marine biota: a survey of bonefish (Albula vulpes) across the Caribbean Basin","volume":"349","author":"Castillo","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2024.107064","article-title":"Differential tissue distribution of pharmaceuticals in a wild subtropical marine fish","volume":"275","author":"Castillo","year":"2024","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb9000","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106705","article-title":"Water temperature affects the biotransformation and accumulation of a psychoactive pharmaceutical and its metabolite in aquatic organisms","volume":"155","author":"Cerveny","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0070","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.scitotenv.2017.11.265","article-title":"Concentrating mixtures of neuroactive pharmaceuticals and altered neurotransmitter levels in the brain of fish exposed to a wastewater effluent","volume":"621","author":"David","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0075","series-title":"Occurrence of pharmaceuticals in a water supply system and related human health risk assessment. Water research, occurrence, fate, removal and assessment of emerging contaminants in water in the water cycle (from wastewater to drinking water)","first-page":"199","volume":"72","author":"de Jesus Gaffney","year":"2015"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0080","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.yrtph.2012.07.003","article-title":"Prioritizing environmental risk of prescription pharmaceuticals","volume":"65","author":"Dong","year":"2013","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.152543","article-title":"Bioconcentration of neuroactive pharmaceuticals in fish: relation to lipophilicity, experimental design and toxicity in the aquatic environment","volume":"812","author":"Duarte","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.120531","article-title":"Neuroactive pharmaceuticals in estuaries: occurrence and tissue-specific bioaccumulation in multiple fish species","volume":"316","author":"Duarte","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0095","series-title":"Pharmaceuticals in Marine and Coastal Environments, Estuarine and Coastal Sciences Series","first-page":"27","article-title":"Occurrence, spatiotemporal distribution and environmental fate of pharmaceutical residues in urban estuaries","author":"Dur\u00e1n-\u00c1lvarez","year":"2021"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0100","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1071\/EN18154","article-title":"Using laboratory incubations to predict the fate of pharmaceuticals in aquatic ecosystems","volume":"15","author":"Fahlman","year":"2018","journal-title":"Environ. Chem."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.157067","article-title":"Implications for the seafood industry, consumers and the environment arising from contamination of shellfish with pharmaceuticals, plastics and potentially toxic elements: a case study from Irish waters with a global orientation","volume":"844","author":"Fehrenbach","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0110","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.yrtph.2010.08.025","article-title":"Predicted critical environmental concentrations for 500 pharmaceuticals","volume":"58","author":"Fick","year":"2010","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0115","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ecoenv.2012.07.013","article-title":"Field and laboratory fish tissue accumulation of the anti-convulsant drug carbamazepine","volume":"84","author":"Garcia","year":"2012","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0120","doi-asserted-by":"crossref","unstructured":"Gerace, E., Salomone, A., Pellegrino, S., Vincenti, M., 2012. Evidence of Haldol (haloperidol) long-term intoxication. Forensic science international, the 48th annual meeting of the International Association of Forensic Toxicologists (TIAFT). Joint Meeting with the Society of Toxicological and Forensic Chemistry (GTFCh). 215, 121\u2013123. doi:https:\/\/doi.org\/10.1016\/j.forsciint.2011.01.038.","DOI":"10.1016\/j.forsciint.2011.01.038"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.160638","article-title":"Bioaccumulation\/bioconcentration of pharmaceutical active compounds in aquatic organisms: assessment and factors database","volume":"861","author":"G\u00f3mez-Regalado","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb8000","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.talanta.2012.08.032","article-title":"Multi-residue method for trace level determination of pharmaceuticals in environmental samples using liquid chromatography coupled to triple quadrupole mass spectrometry","volume":"100","author":"Grabic","year":"2012","journal-title":"Talanta"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0130","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.scitotenv.2014.04.052","article-title":"Tissue-specific bioconcentration of antidepressants in fish exposed to effluent from a municipal sewage treatment plant","volume":"488\u2013489","author":"Grabicova","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125039","article-title":"Bioaccessibility evaluation of pharmaceuticals in market fish with in vitro simulated digestion","volume":"411","author":"Hao","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0140","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s00244-005-0047-2","article-title":"Heavy metal profile in five fish species included in human diet, domiciled in the end flow of river Neretva (Croatia)","volume":"50","author":"Has-Sch\u00f6n","year":"2006","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0145","doi-asserted-by":"crossref","first-page":"13460","DOI":"10.1038\/ncomms13460","article-title":"GABAergic anxiolytic drug in water increases migration behaviour in salmon","volume":"7","author":"Hellstr\u00f6m","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0150","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1071\/EN16027","article-title":"Tissue-specific uptake of the benzodiazepine oxazepam in adult Eurasian perch (Perca fluviatilis)","volume":"13","author":"Heynen","year":"2016","journal-title":"Environ. Chem."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0155","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1093\/biomet\/75.4.800","article-title":"A sharper Bonferroni procedure for multiple tests of significance","volume":"75","author":"Hochberg","year":"1988","journal-title":"Biometrika"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2020.128806","article-title":"Occurrence and distribution of endocrine-disrupting chemicals in mariculture fish and the human health implications","volume":"345","author":"Ismail","year":"2021","journal-title":"Food Chem."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0165","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1139\/cjfas-2017-0308","article-title":"Movement ecology of a mobile predatory fish reveals limited habitat linkages within a temperate estuarine seascape","volume":"75","author":"Kenworthy","year":"2018","journal-title":"Can. J. Fish. Aquat. Sci."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0170","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.scp.2016.07.001","article-title":"Pharmaceuticals in the environment \u2013 a short review on options to minimize the exposure of humans, animals and ecosystems","volume":"5","author":"Klatte","year":"2017","journal-title":"Sustain. Chem. Pharm."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0175","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.scitotenv.2016.05.206","article-title":"Bioaccumulation of five pharmaceuticals at multiple trophic levels in an aquatic food web - insights from a field experiment","volume":"568","author":"Lagesson","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0180","unstructured":"Lenth, R.V., 2023. Emmeans: estimated marginal means, aka least-squares means."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.118898","article-title":"Toxicological effects of atenolol and venlafaxine on zebrafish tissues: bioaccumulation, DNA hypomethylation, and molecular mechanism","volume":"299","author":"Lin","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0190","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.watres.2014.03.076","article-title":"Occurrence and behaviour of 105 active pharmaceutical ingredients in sewage waters of a municipal sewer collection system","volume":"58","author":"Lindberg","year":"2014","journal-title":"Water Res."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0195","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1021\/acs.est.6b04556","article-title":"Antibiotic pollution in marine food webs in Laizhou Bay, North China: Trophodynamics and human exposure implication","volume":"51","author":"Liu","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112874","article-title":"Uptake, elimination, and toxicokinetics of selected pharmaceuticals in multiple tissues of Nile tilapia (Oreochromis niloticus) exposed to environmentally relevant concentrations","volume":"226","author":"Liu","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0205","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1093\/icesjms\/fsy173","article-title":"Assessing red drum spawning aggregations and abundance in the eastern Gulf of Mexico: a multidisciplinary approach","volume":"76","author":"Lowerre-Barbieri","year":"2019","journal-title":"ICES J. Mar. Sci."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.155780","article-title":"Health effects and risks associated with the occurrence of pharmaceuticals and their metabolites in marine organisms and seafood","volume":"837","author":"Madikizela","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.teac.2020.e00104","article-title":"Pharmaceuticals and their metabolites in the marine environment: sources, analytical methods and occurrence","volume":"28","author":"Madikizela","year":"2020","journal-title":"Trends Environ. Anal. Chem."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0220","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1007\/s12237-018-00512-y","article-title":"Trophic relationships and niche partitioning of red drum Sciaenops ocellatus and common Snook Centropomus undecimalis in coastal estuaries of South Florida","volume":"42","author":"Malinowski","year":"2019","journal-title":"Estuar. Coasts"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0225","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0924-977X(02)00048-2","article-title":"Biochemical effects in brain of low doses of haloperidol are qualitatively similar to those of high doses","volume":"12","author":"Marcus","year":"2002","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0230","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ijheh.2019.10.011","article-title":"Presence of pharmaceutical compounds, levels of biochemical biomarkers in seafood tissues and risk assessment for human health: results from a case study in North-Western Spain","volume":"223","author":"Mart\u00ednez-Morcillo","year":"2020","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0235","doi-asserted-by":"crossref","first-page":"8845","DOI":"10.1021\/acs.est.2c09576","article-title":"Factors determining the susceptibility of fish to effects of human pharmaceuticals","volume":"57","author":"Matthee","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0240","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.scitotenv.2017.06.073","article-title":"Exposure to wastewater effluent affects fish behaviour and tissue-specific uptake of pharmaceuticals","volume":"605\u2013606","author":"McCallum","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0245","doi-asserted-by":"crossref","first-page":"8282","DOI":"10.1021\/acs.est.9b01975","article-title":"Slow-release implants for manipulating contaminant exposures in aquatic wildlife: a new tool for field ecotoxicology","volume":"53","author":"McCallum","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0250","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1080\/17425255.2022.2057297","article-title":"Pharmacokinetic drug interactions with oral haloperidol in adults: dose correction factors from a combined weighted analysis","volume":"18","author":"McGrane","year":"2022","journal-title":"Expert Opin. Drug Metab. Toxicol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149744","article-title":"Occurrence of pharmaceuticals in seafood from two Brazilian coastal areas: implication for human risk assessment","volume":"803","author":"Mello","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0260","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.marenvres.2018.05.001","article-title":"Pharmaceuticals in the aquatic environments: evidence of emerged threat and future challenges for marine organisms","volume":"140","author":"Mezzelani","year":"2018","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.116300","article-title":"Multicompartment and cross-species monitoring of contaminants of emerging concern in an estuarine habitat","volume":"270","author":"Miller","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0270","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.scitotenv.2008.05.023","article-title":"Estimates of fish consumption rates for consumers of bought and self-caught fish in Connecticut, Florida, Minnesota, and North Dakota","volume":"403","author":"Moya","year":"2008","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0275","first-page":"531","article-title":"Reproduction, growth, and mortality of red drum Sciaenops ocellatus in Florida waters","author":"Murphy","year":"1990","journal-title":"Fish. Bull."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0280","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.envpol.2019.02.060","article-title":"Occurrence and level of emerging organic contaminant in fish and mollusk from Klang River estuary, Malaysia and assessment on human health risk","volume":"248","author":"Omar","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0285","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1577\/1548-8667(1993)005<0208:UALTTL>2.3.CO;2","article-title":"Upper and lower temperature tolerance limits for juvenile red drums from Texas and South Carolina","volume":"5","author":"Procarione","year":"1993","journal-title":"J. Aquat. Anim. Health"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0290","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.envint.2014.11.020","article-title":"Human health risk assessment of pharmaceuticals and personal care products in plant tissue due to biosolids and manure amendments, and wastewater irrigation","volume":"75","author":"Prosser","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0295","unstructured":"R Core Team, 2023. R: A language and environment for statistical computing."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.envadv.2022.100194","article-title":"Pharmaceuticals are identified in insects in river Fyris \u2013 a study with both tandem quadrupole and quadrupole-time-of-flight mass spectrometry","volume":"8","author":"Sedvall","year":"2022","journal-title":"Environ. Adv."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0305","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1139\/er-2020-0054","article-title":"Pharmaceuticals and personal care products and their sublethal and lethal effects in aquatic organisms","volume":"29","author":"Srain","year":"2021","journal-title":"Environ. Rev."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0310","doi-asserted-by":"crossref","first-page":"11649","DOI":"10.1021\/acs.est.5b02478","article-title":"Uptake and tissue distribution of pharmaceuticals and personal care products in wild fish from treated-wastewater-impacted streams","volume":"49","author":"Tanoue","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0315","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11270-007-9515-9","article-title":"Heavy metal in tissues of three fish species from different trophic levels in a tropical Brazilian river","volume":"187","author":"Terra","year":"2008","journal-title":"Water Air Soil Pollut."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.141800","article-title":"Cross-species extrapolation of chemical sensitivity","volume":"753","author":"van den Berg","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.120502","article-title":"Ecological and human health risks of antibiotics in marine species through mass transfer from sea to land in a coastal area: a case study in Qinzhou Bay, the South China Sea","volume":"316","author":"Wang","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0330","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1021\/acsestwater.2c00553","article-title":"Occurrence and bioaccumulation of psychotropic pharmaceuticals and their metabolites in water and fish in a shallow Lake in China: implications for ecological and human health risks","volume":"3","author":"Weng","year":"2023","journal-title":"ACS EST Water"},{"key":"10.1016\/j.scitotenv.2025.179106_bb0335","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2113947119","article-title":"Pharmaceutical pollution of the world\u2019s rivers","volume":"119","author":"Wilkinson","year":"2022","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.scitotenv.2025.179106_bb0340","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.envpol.2016.12.026","article-title":"Bioaccumulation and trophic transfer of pharmaceuticals in food webs from a large freshwater lake","volume":"222","author":"Xie","year":"2017","journal-title":"Environ. Pollut."}],"container-title":["Science of The Total Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969725007417?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048969725007417?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T02:08:14Z","timestamp":1775786894000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048969725007417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":70,"alternative-id":["S0048969725007417"],"URL":"https:\/\/doi.org\/10.1016\/j.scitotenv.2025.179106","relation":{},"ISSN":["0048-9697"],"issn-type":[{"value":"0048-9697","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Occurrence of pharmaceuticals in muscle tissue of red drum (Sciaenops ocellatus) across subtropical estuaries: Comparison to blood plasma and implications for human exposure","name":"articletitle","label":"Article Title"},{"value":"Science of The Total Environment","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scitotenv.2025.179106","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"179106"}}