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Sci."},{"issue":"May 2015","key":"10.1016\/j.scitotenv.2025.180716_bb0325","article-title":"Delivery of crop pollination services is an insufficient argument for wild pollinator conservation. Nature","volume":"6","author":"Kleijn","year":"2015","journal-title":"Communications"},{"issue":"October","key":"10.1016\/j.scitotenv.2025.180716_bb0330","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1093\/ee\/nvz117","article-title":"Bombus (Hymenoptera: Apidae) microcolonies as a tool for biological understanding and pesticide risk assessment","volume":"48","author":"Klinger","year":"2019","journal-title":"Environ. Entomol."},{"issue":"1984","key":"10.1016\/j.scitotenv.2025.180716_bb0335","article-title":"Nutritional stress exacerbates impact of a novel insecticide on solitary bees\u2019 behaviour, reproduction and survival","volume":"289","author":"Knauer","year":"2022","journal-title":"Proc. R. Soc. B Biol. Sci."},{"issue":"1","key":"10.1016\/j.scitotenv.2025.180716_bb0340","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1093\/ee\/nvab119","article-title":"Effects of provision type and pesticide exposure on the larval development of Osmia lignaria (Hymenoptera: Megachilidae)","volume":"51","author":"Kopit","year":"2022","journal-title":"Environ. Entomol."},{"issue":"10","key":"10.1016\/j.scitotenv.2025.180716_bb0345","article-title":"Collection and analysis of pesticide residue data for pollen and nectar - Final report","volume":"14","author":"Kyriakopoulou","year":"2017","journal-title":"EFSA J."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0350","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.cois.2021.05.004","article-title":"Pollinator decline: what do we know about the drivers of solitary bee declines?","volume":"46","author":"LeBuhn","year":"2021","journal-title":"Curr. Opin. Insect Sci."},{"issue":"1","key":"10.1016\/j.scitotenv.2025.180716_bb0355","first-page":"1","article-title":"Dissipation of the insecticide cyantraniliprole and its metabolite IN-J9Z38 in proso millet during cultivation","volume":"9","author":"Lee","year":"2019","journal-title":"Sci. Rep."},{"issue":"1880","key":"10.1016\/j.scitotenv.2025.180716_bb0360","first-page":"1","article-title":"Effects of neonicotinoid insecticide exposure and monofloral diet on nest-founding bumblebee queens","volume":"285","author":"Leza","year":"2018","journal-title":"Proc. R. Soc. B Biol. Sci."},{"issue":"12 December","key":"10.1016\/j.scitotenv.2025.180716_bb0365","first-page":"1","article-title":"Increase in longevity and amelioration of pesticide toxicity by natural levels of dietary phytochemicals in the honey bee, Apis mellifera","volume":"15","author":"Liao","year":"2020","journal-title":"PloS One"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.148680","article-title":"Sulfoxaflor and nutritional deficiency synergistically reduce survival and fecundity in bumblebees","volume":"795","author":"Linguadoca","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"31","key":"10.1016\/j.scitotenv.2025.180716_bb0375","doi-asserted-by":"crossref","first-page":"12657","DOI":"10.1073\/pnas.1109535108","article-title":"CYP9Q-mediated detoxification of acaricides in the honey bee (Apis mellifera)","volume":"108","author":"Mao","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.scitotenv.2025.180716_bb0380","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.1614864114","article-title":"Disruption of quercetin metabolism by fungicide affects energy production in honey bees (Apis mellifera)","volume":"114","author":"Mao","year":"2017","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"5325","key":"10.1016\/j.scitotenv.2025.180716_bb0385","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1126\/science.277.5325.504","article-title":"Agricultural intensification and ecosystem properties","volume":"277","author":"Matson","year":"1997","journal-title":"Science"},{"issue":"11","key":"10.1016\/j.scitotenv.2025.180716_bb0390","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0165-6147(00)01820-4","article-title":"Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors","volume":"22","author":"Matsuda","year":"2001","journal-title":"Trends Pharmacol. Sci."},{"issue":"12","key":"10.1016\/j.scitotenv.2025.180716_bb0395","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0168462","article-title":"Interspecific variation in bumblebee performance on pollen diet: new insights for mitigation strategies","volume":"11","author":"Moerman","year":"2016","journal-title":"PloS One"},{"issue":"2","key":"10.1016\/j.scitotenv.2025.180716_bb0400","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/icad.12213","article-title":"Pollen nutrients better explain bumblebee colony development than pollen diversity","volume":"10","author":"Moerman","year":"2017","journal-title":"Insect Conserv. Divers."},{"issue":"41","key":"10.1016\/j.scitotenv.2025.180716_bb0405","doi-asserted-by":"crossref","first-page":"10305","DOI":"10.1073\/pnas.1803880115","article-title":"Glyphosate perturbs the gut microbiota of honey bees","volume":"115","author":"Motta","year":"2018","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"3","key":"10.1016\/j.scitotenv.2025.180716_bb0410","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0009754","article-title":"High levels of miticides and agrochemicals in North American apiaries: implications for honey bee health","volume":"5","author":"Mullin","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0415","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.133771","article-title":"Acute oral toxicity and risks of four classes of systemic insecticide to the Common Eastern Bumblebee (Bombus impatiens)","volume":"295","author":"Mundy-Heisz","year":"2022","journal-title":"Chemosphere"},{"issue":"5","key":"10.1016\/j.scitotenv.2025.180716_bb0420","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1603\/0046-225X-33.5.1151","article-title":"Effects of selected fungicides on growth and development of larval honey bees, Apis mellifera L. (Hymenoptera: Apidae)","volume":"33","author":"Mussen","year":"2004","journal-title":"Environ. Entomol."},{"issue":"6","key":"10.1016\/j.scitotenv.2025.180716_bb0425","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.it.2011.03.004","article-title":"E-cadherin: gatekeeper of airway mucosa and allergic sensitization","volume":"32","author":"Nawijn","year":"2011","journal-title":"Trends Immunol."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2019.103495","article-title":"Hemocytin facilitates host immune responses against Nosema bombycis","volume":"103","author":"Ni","year":"2020","journal-title":"Dev. Comp. Immunol."},{"issue":"2","key":"10.1016\/j.scitotenv.2025.180716_bb0435","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1080\/15627020.2011.11407495","article-title":"Bee food: The chemistry and nutritional value of nectar, pollen and mixtures of the two","volume":"46","author":"Nicolson","year":"2011","journal-title":"Afr. Zool."},{"issue":"7","key":"10.1016\/j.scitotenv.2025.180716_bb0440","doi-asserted-by":"crossref","DOI":"10.1016\/S0021-9258(18)32623-1","article-title":"A phospholipase A1 from the hemolymph of the tobacco hornworm, Manduca sexta*","volume":"258","author":"Nieder","year":"1983","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.scitotenv.2025.180716_bb0445","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1600-0706.2010.18644.x","article-title":"How many flowering plants are pollinated by animals?","volume":"120","author":"Ollerton","year":"2011","journal-title":"Oikos"},{"issue":"6","key":"10.1016\/j.scitotenv.2025.180716_bb0450","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.aller.2016.10.011","article-title":"A critical review on serine protease: key immune manipulator and pathology mediator","volume":"45","author":"Patel","year":"2017","journal-title":"Allergol. Immunopathol."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0455","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ibmb.2018.12.011","article-title":"Insect venom phospholipases A1 and A2: roles in the envenoming process and allergy","volume":"105","author":"Perez-Riverol","year":"2019","journal-title":"Insect Biochem. Mol. Biol."},{"issue":"14","key":"10.1016\/j.scitotenv.2025.180716_bb0460","doi-asserted-by":"crossref","first-page":"3469","DOI":"10.1007\/s10531-015-1008-3","article-title":"Bumble bees show trait-dependent vulnerability to landscape simplification","volume":"24","author":"Persson","year":"2015","journal-title":"Biodivers. Conserv."},{"issue":"7","key":"10.1016\/j.scitotenv.2025.180716_bb0465","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1139\/z93-192","article-title":"An experimental study of the effect of colony resource level manipulation on foraging for pollen by worker bumble bees (Hymenoptera: Apidae)","volume":"71","author":"Plowright","year":"2008","journal-title":"Can. J. Zool."},{"issue":"6","key":"10.1016\/j.scitotenv.2025.180716_bb0470","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.tree.2010.01.007","article-title":"Global pollinator declines: trends, impacts and drivers","volume":"25","author":"Potts","year":"2010","journal-title":"Trends Ecol. Evol."},{"issue":"7632","key":"10.1016\/j.scitotenv.2025.180716_bb0475","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/nature20588","article-title":"Safeguarding pollinators and their values to human well-being","volume":"540","author":"Potts","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0480","series-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2023"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0485","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jip.2014.08.007","article-title":"Widespread occurrence of honey bee pathogens in solitary bees","volume":"122","author":"Ravoet","year":"2014","journal-title":"J. Invertebr. Pathol."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0490","series-title":"Contribution \u00e0 l \u2019\u00e9tude des besoins alimentaires en st\u00e9ro\u00efdes de Bombus terrestris (L.)","author":"Regali","year":"1996"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0495","article-title":"The drosophila serpins: multiple functions in immunity and morphogenesis","volume":"499","author":"Reichhart","year":"2011","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0500","series-title":"2012-2013 National Honey Bee Pests and Diseases Survey Report","first-page":"1","author":"Rennich","year":"2013"},{"issue":"1","key":"10.1016\/j.scitotenv.2025.180716_bb0505","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1186\/1471-2164-15-1031","article-title":"Differential gene expression and alternative splicing in insect immune specificity","volume":"15","author":"Riddell","year":"2014","journal-title":"BMC Genomics"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0510","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jinsphys.2016.11.002","article-title":"Diet effects on bumblebee health","volume":"96","author":"Roger","year":"2017","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0515","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1023\/A:1016048526475","article-title":"The effect of pollen protein concentration on body size in the sweat bee Lasioglossum zephyrum (Hymenoptera: Apiformes)","volume":"16","author":"Roulston","year":"2002","journal-title":"Evol. Ecol."},{"issue":"10","key":"10.1016\/j.scitotenv.2025.180716_bb0520","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1111\/j.1558-5646.2011.01345.x","article-title":"Food-environment mediates the outcome of specific interactions between a bumblebee and its trypanosome parasite","volume":"65","author":"Sadd","year":"2011","journal-title":"Evolution"},{"issue":"4","key":"10.1016\/j.scitotenv.2025.180716_bb0525","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0094482","article-title":"Pesticide residues and bees - a risk assessment","volume":"9","author":"Sanchez-Bayo","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0530","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jinsphys.2014.10.002","article-title":"Genomic analysis of the interaction between pesticide exposure and nutrition in honey bees (Apis mellifera)","volume":"71","author":"Schmehl","year":"2014","journal-title":"J. Insect Physiol."},{"issue":"5","key":"10.1016\/j.scitotenv.2025.180716_bb0535","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s002650050442","article-title":"Effects of colony food shortage on behavioral development in honey bees","volume":"42","author":"Schulz","year":"1998","journal-title":"Behav. Ecol. Sociobiol."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0540","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107252","article-title":"No evidence for impaired solitary bee fitness following pre-flowering sulfoxaflor application alone or in combination with a common fungicide in a semi-field experiment","volume":"164","author":"Schwarz","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0545","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.169494","article-title":"Diverse pollen nutrition can improve the development of solitary bees but does not mitigate negative pesticide impacts","volume":"912","author":"Schwarz","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.180716_bb1000","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1603\/029.102.0125","article-title":"Impact of currently used or potentially useful insecticides for canola agroecosystems on Bombus impatiens (Hymenoptera: Apidae), Megachile rotundata (Hymenoptera: Megachilidae), and Osmia lignaria (Hymenoptera: Megachilidae)","volume":"102","author":"Scott-Dupree","year":"2009","journal-title":"J. Econ. Entomol."},{"issue":"5","key":"10.1016\/j.scitotenv.2025.180716_bb0550","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0010435","article-title":"Flavin-dependent monooxygenases as a detoxification mechanism in insects: new insights from the arctiids (Lepidoptera)","volume":"5","author":"Sehlmeyer","year":"2010","journal-title":"PloS One"},{"issue":"1885","key":"10.1016\/j.scitotenv.2025.180716_bb0555","doi-asserted-by":"crossref","first-page":"20180887","DOI":"10.1098\/rspb.2018.0887","article-title":"Combined exposure to sublethal concentrations of an insecticide and a fungicide affect feeding, ovary development, and longevity in a solitary bee","volume":"285","author":"Sgolastra","year":"2018","journal-title":"Proc. R. Soc. B"},{"issue":"3","key":"10.1016\/j.scitotenv.2025.180716_bb0560","doi-asserted-by":"crossref","DOI":"10.1002\/arch.21556","article-title":"Role of serine protease inhibitors in insect-host-pathogen interactions","volume":"102","author":"Shakeel","year":"2019","journal-title":"Arch. Insect Biochem. Physiol."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0565","article-title":"Structure, function and evolution of glutathione transferases\u00a0: implications for classification of non-mammalian members of an ancient enzyme superfamily. In","volume":"360","author":"Sheehan","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0570","series-title":"The Ubiquitous Roles of Cytochrome P450 Proteins (Chichester, Vol. 3)","year":"2007"},{"issue":"1935","key":"10.1016\/j.scitotenv.2025.180716_bb0575","article-title":"Do novel insecticides pose a threat to beneficial insects?","volume":"287","author":"Siviter","year":"2020","journal-title":"Proc. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0580","series-title":"Agrochemicals, But not Other Stressors, Interact Synergistically to Increase Bee Mortality S.I","author":"Siviter","year":"2021"},{"issue":"5","key":"10.1016\/j.scitotenv.2025.180716_bb0585","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1242\/jeb.114249","article-title":"Nutrient balancing of the adult worker bumblebee (Bombus terrestris) depends on the dietary source of essential amino acids","volume":"218","author":"Stabler","year":"2015","journal-title":"J. Exp. Biol."},{"issue":"5","key":"10.1016\/j.scitotenv.2025.180716_bb0590","doi-asserted-by":"crossref","DOI":"10.1111\/1365-2664.12689","article-title":"Investigating the impacts of field-realistic exposure to a neonicotinoid pesticide on bumblebee foraging, homing ability and colony growth","volume":"53","author":"Stanley","year":"2016","journal-title":"J. Appl. Ecol."},{"issue":"December","key":"10.1016\/j.scitotenv.2025.180716_bb0595","first-page":"1","article-title":"Current pesticide risk assessment protocols do not adequately address differences between honey bees (Apis mellifera) and bumble bees (Bombus spp.)","volume":"4","author":"Stoner","year":"2016","journal-title":"Front. Environ. Sci."},{"issue":"3","key":"10.1016\/j.scitotenv.2025.180716_bb0600","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1051\/apido\/2009023","article-title":"Ecological impacts of invasive alien species on bees","volume":"40","author":"Stout","year":"2009","journal-title":"Apidologie"},{"issue":"6","key":"10.1016\/j.scitotenv.2025.180716_bb0605","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1139\/z90-166","article-title":"The effects of pollen availability on development time in the bumble bee Bombus terricola K. (Hymenoptera: Apidae)","volume":"68","author":"Sutcliffe","year":"1990","journal-title":"Can. J. Zool."},{"issue":"10","key":"10.1016\/j.scitotenv.2025.180716_bb0610","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1007\/BF01943139","article-title":"Definitive evidence for lack of phytosterol dealkylation in honey bees","volume":"39","author":"Svoboda","year":"1983","journal-title":"Experientia"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0615","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106813","article-title":"Fungicide and insecticide exposure adversely impacts bumblebees and pollination services under semi-field conditions","volume":"157","author":"Tamburini","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0620","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146084","article-title":"Sulfoxaflor insecticide and azoxystrobin fungicide have no major impact on honeybees in a realistic-exposure semi-field experiment","volume":"778","author":"Tamburini","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.scitotenv.2025.180716_bb0625","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1051\/apido:2008017","article-title":"Original article Nutritive value of 15 single pollens and pollen mixes tested on larvae produced by bumblebee workers (Bombus terrestris, Hymenoptera: Apidae)*","volume":"39","author":"Tase\u00ef","year":"2008","journal-title":"Apidologie"},{"issue":"April","key":"10.1016\/j.scitotenv.2025.180716_bb0630","first-page":"809","article-title":"The relevance of sublethal effects in honey bee testing for pesticide risk assessment","volume":"63","author":"Thompson","year":"2007","journal-title":"Pest Manag. Sci."},{"issue":"7","key":"10.1016\/j.scitotenv.2025.180716_bb0635","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1002\/ps.3868","article-title":"Neonicotinoids and bumblebees (Bombus terrestris): effects on nectar consumption in individual workers","volume":"71","author":"Thompson","year":"2015","journal-title":"Pest Manag. Sci."},{"issue":"6","key":"10.1016\/j.scitotenv.2025.180716_bb0640","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0038406","article-title":"Imidacloprid-induced impairment of mushroom bodies and behavior of the native stingless bee Melipona quadrifasciata anthidioides","volume":"7","author":"Tom\u00e9","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.scitotenv.2025.180716_bb0645","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113420","article-title":"Frequently encountered pesticides can cause multiple disorders in developing worker honey bees","volume":"256","author":"Tom\u00e9","year":"2020","journal-title":"Environ. Pollut."},{"issue":"1900","key":"10.1016\/j.scitotenv.2025.180716_bb0650","article-title":"Lethal and sublethal synergistic effects of a new systemic pesticide, flupyradifurone (Sivantow), on honeybees","volume":"286","author":"Tosi","year":"2019","journal-title":"Proc. R. Soc. B Biol. Sci."},{"issue":"1869","key":"10.1016\/j.scitotenv.2025.180716_bb0655","article-title":"Neonicotinoid pesticides and nutritional stress synergistically reduce survival in honey bees","volume":"284","author":"Tosi","year":"2017","journal-title":"Proc. R. Soc. B Biol. Sci."},{"issue":"1","key":"10.1016\/j.scitotenv.2025.180716_bb0660","first-page":"1","article-title":"A common neonicotinoid pesticide, thiamethoxam, impairs honey bee flight ability","volume":"7","author":"Tosi","year":"2017","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.scitotenv.2025.180716_bb0665","doi-asserted-by":"crossref","DOI":"10.1093\/iob\/obad014","article-title":"The effect of pollen diet composition and quantity on diapause survival and performance in an annual pollinator (Bombus Impatiens)","volume":"5","author":"Treanore","year":"2023","journal-title":"Integr. Organismal Biol."},{"issue":"1","key":"10.1016\/j.scitotenv.2025.180716_bb0670","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/eji.201243168","article-title":"E-cadherin: from epithelial glue to immunological regulator. In","volume":"43","author":"Van den Bossche","year":"2013","journal-title":"Eur. J. 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