{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T22:07:47Z","timestamp":1791151667643,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"crossref","award":["SFB 1002"],"award-info":[{"award-number":["SFB 1002"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"crossref","award":["01GS0837"],"award-info":[{"award-number":["01GS0837"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Max Planck Society"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.scr.2013.05.005","type":"journal-article","created":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T02:48:11Z","timestamp":1369709291000},"page":"806-819","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":172,"title":["Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome"],"prefix":"10.1016","volume":"11","author":[{"given":"Jan","family":"Dudek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I-Fen","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Balleininger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric M.","family":"Vaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Streckfuss-B\u00f6meke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"H\u00fcbscher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena","family":"Vukotic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald J.A.","family":"Wanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Rehling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaomei","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scr.2013.05.005_bb0035","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/labinvest.3700480","article-title":"Comparison of lymphoblast mitochondria from normal subjects and patients with Barth syndrome using electron microscopic tomography","volume":"87","author":"Acehan","year":"2007","journal-title":"Lab. Invest."},{"key":"10.1016\/j.scr.2013.05.005_bb0185","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1074\/jbc.M110.171439","article-title":"Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome","volume":"286","author":"Acehan","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0085","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.molcel.2008.10.021","article-title":"Respiratory active mitochondrial supercomplexes","volume":"32","author":"Ac\u00edn-P\u00e9rez","year":"2008","journal-title":"Mol. Cell."},{"key":"10.1016\/j.scr.2013.05.005_bb0165","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0378-1119(92)90287-Y","article-title":"Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase","volume":"119","author":"Arnaudo","year":"1992","journal-title":"Gene"},{"key":"10.1016\/j.scr.2013.05.005_bb0155","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1006\/geno.1997.4687","article-title":"Structure of the human gene (COX6A2) for the heart\/muscle isoform of cytochrome c oxidase subunit VIa and its chromosomal location in humans, mice, and cattle","volume":"42","author":"Bachman","year":"1997","journal-title":"Genomics"},{"key":"10.1016\/j.scr.2013.05.005_bb0005","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0022-510X(83)90209-5","article-title":"An X-linked mitochondrial disease affecting cardiac muscle, skeletal muscle and neutrophil leucocytes","volume":"62","author":"Barth","year":"1983","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.scr.2013.05.005_bb0175","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF01799418","article-title":"X-linked cardioskeletal myopathy and neutropenia (Barth syndrome): respiratory-chain abnormalities in cultured fibroblasts","volume":"19","author":"Barth","year":"1996","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.scr.2013.05.005_bb0150","article-title":"Cardiolipin-dependent reconstitution of respiratory supercomplexes from purified Saccharomyces cerevisiae complexes III and IV","author":"Baz\u00e1n","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0125","doi-asserted-by":"crossref","first-page":"5202","DOI":"10.1091\/mbc.E05-03-0256","article-title":"Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome","volume":"16","author":"Brandner","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.scr.2013.05.005_bb0265","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1111\/j.1365-2958.2008.06216.x","article-title":"Loss of tafazzin in yeast leads to increased oxidative stress during respiratory growth","volume":"68","author":"Chen","year":"2008","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.scr.2013.05.005_bb0100","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.cmet.2012.02.006","article-title":"Identification of a protein mediating respiratory supercomplex stability","volume":"15","author":"Chen","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.scr.2013.05.005_bb0245","doi-asserted-by":"crossref","first-page":"5869","DOI":"10.1021\/bi7023282","article-title":"Shotgun lipidomics reveals the temporally dependent, highly diversified cardiolipin profile in the mammalian brain: temporally coordinated postnatal diversification of cardiolipin molecular species with neuronal remodeling","volume":"47","author":"Cheng","year":"2008","journal-title":"Biochemistry"},{"key":"10.1016\/j.scr.2013.05.005_bb0225","first-page":"535","article-title":"Characterization of the preprotein translocase of the outer mitochondrial membrane by blue native electrophoresis","volume":"377","author":"Dekker","year":"1996","journal-title":"Biol. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0270","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/00004872-200018060-00002","article-title":"Role of oxidative stress in cardiovascular diseases","volume":"18","author":"Dhalla","year":"2000","journal-title":"J. Hypertens."},{"key":"10.1016\/j.scr.2013.05.005_bb0040","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1016\/j.cub.2009.10.074","article-title":"Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome","volume":"19","author":"Gebert","year":"2009","journal-title":"Curr. Biol."},{"key":"10.1016\/j.scr.2013.05.005_bb0160","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0167-4781(97)00025-0","article-title":"Nuclear genes for cytochrome c oxidase","volume":"1352","author":"Grossman","year":"1997","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.scr.2013.05.005_bb0065","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1016\/j.bbamem.2009.07.009","article-title":"The enigmatic role of tafazzin in cardiolipin metabolism","volume":"1788","author":"Houtkooper","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.scr.2013.05.005_bb0235","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1373\/clinchem.2007.095711","article-title":"Bloodspot assay using HPLC\u2013tandem mass spectrometry for detection of Barth syndrome","volume":"54","author":"Kulik","year":"2008","journal-title":"Clin. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0115","doi-asserted-by":"crossref","first-page":"6591","DOI":"10.1093\/emboj\/20.23.6591","article-title":"Specific roles of protein\u2013phospholipid interactions in the yeast cytochrome bc1 complex structure","volume":"20","author":"Lange","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.scr.2013.05.005_bb0230","doi-asserted-by":"crossref","first-page":"6701","DOI":"10.1111\/j.1742-4658.2009.07384.x","article-title":"Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria","volume":"276","author":"Lazarou","year":"2009","journal-title":"FEBS J."},{"key":"10.1016\/j.scr.2013.05.005_bb0170","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/BF00303255","article-title":"Structure and chromosomal location of the bovine gene for the heart muscle isoform of cytochrome c oxidase subunit VIII. Mammalian genome: official","volume":"6","author":"Lomax","year":"1995","journal-title":"J. Int. Mamm. Genome"},{"key":"10.1016\/j.scr.2013.05.005_bb0060","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.jmb.2006.06.057","article-title":"Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients","volume":"361","author":"Mckenzie","year":"2006","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.scr.2013.05.005_bb0080","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.cmet.2012.01.015","article-title":"Mitochondrial complex I plays an essential role in human respirasome assembly","volume":"15","author":"Moreno-Lastres","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.scr.2013.05.005_bb0020","doi-asserted-by":"crossref","first-page":"R465-R466","DOI":"10.1016\/S0960-9822(06)00237-5","article-title":"Barth syndrome may be due to an acyltransferase deficiency","volume":"7","author":"Neuwald","year":"1997","journal-title":"Curr. Biol."},{"key":"10.1016\/j.scr.2013.05.005_bb0215","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/s12015-009-9103-z","article-title":"Presence of a ROCK inhibitor in extracellular matrix supports more undifferentiated growth of feeder-free human embryonic and induced pluripotent stem cells upon passaging","volume":"6","author":"Pakzad","year":"2010","journal-title":"Stem Cell Rev."},{"key":"10.1016\/j.scr.2013.05.005_bb0120","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/nature02056","article-title":"Structure of mitochondrial ADP\/ATP carrier in complex with carboxyatractyloside","volume":"426","author":"Pebay-Peyroula","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.scr.2013.05.005_bb0140","doi-asserted-by":"crossref","first-page":"52873","DOI":"10.1074\/jbc.M308366200","article-title":"Cardiolipin stabilizes respiratory chain supercomplexes","volume":"278","author":"Pfeiffer","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0195","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.111.000455","article-title":"Tafazzin knockdown in mice leads to a developmental cardiomyopathy with early diastolic dysfunction preceding myocardial noncompaction","volume":"1","author":"Phoon","year":"2012","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.scr.2013.05.005_bb0200","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/nature10761","article-title":"The promise of induced pluripotent stem cells in research and therapy","volume":"481","author":"Robinton","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.scr.2013.05.005_bb0075","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1093\/emboj\/19.8.1777","article-title":"Supercomplexes in the respiratory chains of yeast and mammalian mitochondria","volume":"19","author":"Sch\u00e4gger","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.scr.2013.05.005_bb0070","doi-asserted-by":"crossref","first-page":"37861","DOI":"10.1074\/jbc.M106474200","article-title":"The ratio of oxidative phosphorylation complexes I\u2013V in bovine heart mitochondria and the composition of respiratory chain supercomplexes","volume":"276","author":"Sch\u00e4gger","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0050","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/ana.10176","article-title":"Deficiency of tetralinoleoyl-cardiolipin in Barth syndrome","volume":"51","author":"Schlame","year":"2002","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.scr.2013.05.005_bb0045","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1016\/j.jacc.2003.06.015","article-title":"Phospholipid abnormalities in children with Barth syndrome","volume":"42","author":"Schlame","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.scr.2013.05.005_bb0105","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1016\/j.bbabio.2012.04.015","article-title":"The stability and activity of respiratory complex II is cardiolipin-dependent","volume":"1817","author":"Schwall","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.scr.2013.05.005_bb0180","doi-asserted-by":"crossref","first-page":"14966","DOI":"10.1021\/bi9914053","article-title":"Phospholipase A(2) digestion of cardiolipin bound to bovine cytochrome c oxidase alters both activity and quaternary structure","volume":"38","author":"Sedl\u00e1k","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/j.scr.2013.05.005_bb0110","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1038\/sj.emboj.7601618","article-title":"Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase","volume":"26","author":"Shinzawa-Itoh","year":"2007","journal-title":"EMBO J."},{"key":"10.1016\/j.scr.2013.05.005_bb0220","doi-asserted-by":"crossref","first-page":"3315","DOI":"10.1021\/bi00713a022","article-title":"Studies on the mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles","volume":"13","author":"Sims","year":"1974","journal-title":"Biochemistry"},{"key":"10.1016\/j.scr.2013.05.005_bb0190","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1089\/hum.2010.199","article-title":"Characterization of a transgenic short hairpin RNA-induced murine model of tafazzin deficiency","volume":"22","author":"Soustek","year":"2011","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.scr.2013.05.005_bb0010","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1007\/s00246-005-0873-z","article-title":"Ventricular arrhythmia in the X-linked cardiomyopathy Barth syndrome","volume":"26","author":"Spencer","year":"2005","journal-title":"Pediatr. Cardiol."},{"key":"10.1016\/j.scr.2013.05.005_bb0240","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1002\/pd.2599","article-title":"Barth syndrome: an X-linked cause of fetal cardiomyopathy and stillbirth","volume":"30","author":"Steward","year":"2010","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.scr.2013.05.005_bb0210","article-title":"Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts","author":"Streckfuss-Bomeke","year":"2012","journal-title":"Eur. Hear. J."},{"key":"10.1016\/j.scr.2013.05.005_bb0095","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1128\/MCB.06369-11","article-title":"Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex","volume":"32","author":"Strogolova","year":"2012","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.scr.2013.05.005_bb0015","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1007\/s00431-011-1575-6","article-title":"Eponym: Barth syndrome","volume":"170","author":"Takeda","year":"2011","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.scr.2013.05.005_bb0255","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1126\/science.272.5265.1136","article-title":"The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A","volume":"272","author":"Tsukihara","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.scr.2013.05.005_bb0055","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1093\/clinchem\/48.9.1390","article-title":"Quantitative and compositional study of cardiolipin in platelets by electrospray ionization mass spectrometry: application for the identification of Barth syndrome patients","volume":"48","author":"Valianpour","year":"2002","journal-title":"Clin. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0250","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1194\/jlr.M200217-JLR200","article-title":"Linoleic acid supplementation of Barth syndrome fibroblasts restores cardiolipin levels: implications for treatment","volume":"44","author":"Valianpour","year":"2003","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.scr.2013.05.005_bb0090","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.cmet.2012.01.016","article-title":"Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex","volume":"15","author":"Vukotic","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.scr.2013.05.005_bb0135","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.bbabio.2009.02.012","article-title":"Role of phospholipids in respiratory cytochrome bc(1) complex catalysis and supercomplex formation","volume":"1787","author":"Wenz","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.scr.2013.05.005_bb0260","article-title":"Seven functional classes of Barth syndrome mutation","author":"Whited","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.scr.2013.05.005_bb0205","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/ncb0511-497","article-title":"Harnessing the potential of induced pluripotent stem cells for regenerative medicine","volume":"13","author":"Wu","year":"2011","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.scr.2013.05.005_bb0030","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/labinvest.3700274","article-title":"Characterization of lymphoblast mitochondria from patients with Barth syndrome","volume":"85","author":"Xu","year":"2005","journal-title":"Lab. Invest."},{"key":"10.1016\/j.scr.2013.05.005_bb0025","doi-asserted-by":"crossref","first-page":"39217","DOI":"10.1074\/jbc.M606100200","article-title":"The enzymatic function of tafazzin","volume":"281","author":"Xu","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0275","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0022-2828(87)80583-7","article-title":"Ultrastructural changes induced in the isolated rat heart by enzymatically generated oxygen radicals","volume":"19","author":"Ytrehus","year":"1987","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.scr.2013.05.005_bb0130","doi-asserted-by":"crossref","first-page":"43553","DOI":"10.1074\/jbc.C200551200","article-title":"Gluing the respiratory chain together","volume":"277","author":"Zhang","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.scr.2013.05.005_bb0145","article-title":"Cardiolipin is essential for organization of complexes III and IV into a supercomplex in intact yeast mitochondria","author":"Zhang","year":"2005","journal-title":"J. Biol. Chem."}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506113000548?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506113000548?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T18:49:21Z","timestamp":1645555761000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506113000548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":55,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S1873506113000548"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2013.05.005","relation":{},"ISSN":["1873-5061"],"issn-type":[{"value":"1873-5061","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2013.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}