{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T09:47:14Z","timestamp":1790156834081,"version":"4.0.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,5,26]],"date-time":"2015-05-26T00:00:00Z","timestamp":1432598400000},"content-version":"vor","delay-in-days":571,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Stem Cell Research PhD Program"},{"name":"University of Catania, Catania, Italy"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.scr.2013.07.003","type":"journal-article","created":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T03:32:54Z","timestamp":1374723174000},"page":"1037-1044","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":72,"title":["Efficacy of adipose tissue-mesenchymal stem cell transplantation in rats with acetaminophen liver injury"],"prefix":"10.1016","volume":"11","author":[{"given":"Federico","family":"Salomone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignazio","family":"Barbagallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Puzzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cateno","family":"Piazza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Li Volti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scr.2013.07.003_bb0005","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/hep.21704","article-title":"Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes","volume":"46","author":"Banas","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.scr.2013.07.003_bb0010","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1634\/stemcells.2008-0034","article-title":"IFATS collection: in vivo therapeutic potential of human adipose tissue mesenchymal stem cells after transplantation into mice with liver injury","volume":"26","author":"Banas","year":"2008","journal-title":"Stem Cells"},{"key":"10.1016\/j.scr.2013.07.003_bb0015","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1089\/ars.2007.1956","article-title":"F2-isoprostanes in human health and diseases: from molecular mechanisms to clinical implications","volume":"10","author":"Basu","year":"2008","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.scr.2013.07.003_bb0020","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1634\/stemcells.22-4-625","article-title":"Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood","volume":"22","author":"Bieback","year":"2004","journal-title":"Stem Cells"},{"key":"10.1016\/j.scr.2013.07.003_bb0025","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1124\/jpet.105.088898","article-title":"Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity","volume":"315","author":"Cover","year":"2005","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.scr.2013.07.003_bb0030","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3109\/10715760903513017","article-title":"Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1","volume":"44","author":"Das","year":"2010","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.scr.2013.07.003_bb0035","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/nbt1274","article-title":"Isolation of amniotic stem cell lines with potential for therapy","volume":"25","author":"De Coppi","year":"2007","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.scr.2013.07.003_bb0040","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.freeradbiomed.2009.11.023","article-title":"Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection","volume":"48","author":"Ghosh","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.scr.2013.07.003_bb0045","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1053\/j.gastro.2006.03.045","article-title":"c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity","volume":"131","author":"Gunawan","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.scr.2013.07.003_bb0050","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1136\/gut.2006.104372","article-title":"Critical role of c-Jun (NH2) terminal kinase in paracetamol-induced acute liver failure","volume":"56","author":"Henderson","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.scr.2013.07.003_bb0055","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1634\/stemcells.2004-0058","article-title":"Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta","volume":"22","author":"In 't Anker","year":"2004","journal-title":"Stem Cells"},{"key":"10.1016\/j.scr.2013.07.003_bb0060","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3109\/03602532.2011.602688","article-title":"Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity","volume":"44","author":"Jaeschke","year":"2012","journal-title":"Drug Metab. Rev."},{"key":"10.1016\/j.scr.2013.07.003_bb0065","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1093\/toxsci\/kfg181","article-title":"Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation","volume":"75","author":"James","year":"2003","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.scr.2013.07.003_bb0070","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1634\/stemcells.2005-0342","article-title":"Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue","volume":"24","author":"Kern","year":"2006","journal-title":"Stem Cells"},{"key":"10.1016\/j.scr.2013.07.003_bb0075","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1124\/jpet.102.038968","article-title":"Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: protection by glutathione","volume":"303","author":"Knight","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.scr.2013.07.003_bb0080","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1440-1746.2011.06798.x","article-title":"Efficacy of adipose tissue-derived mesenchymal stem cells for fulminant hepatitis in mice induced by concanavalin A","volume":"27","author":"Kubo","year":"2012","journal-title":"J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.scr.2013.07.003_bb0085","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1053\/j.gastro.2008.03.015","article-title":"Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells","volume":"134","author":"Kuo","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.scr.2013.07.003_bb0090","article-title":"AASLD position paper: the management of acute liver failure: update 2011","author":"Lee","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.scr.2013.07.003_bb0095","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1126\/science.284.5411.143","article-title":"Multilineage potential of adult human mesenchymal stem cells","volume":"284","author":"Pittenger","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.scr.2013.07.003_bb0100","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/hep.23267","article-title":"Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine","volume":"51","author":"Saito","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.scr.2013.07.003_bb0105","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1182\/blood-2005-02-0572","article-title":"Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion","volume":"106","author":"Sato","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.scr.2013.07.003_bb0110","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.jhep.2010.05.010","article-title":"Barriers to the successful treatment of liver disease by hepatocyte transplantation","volume":"53","author":"Soltys","year":"2010","journal-title":"J. Hepatol."},{"key":"10.1016\/j.scr.2013.07.003_bb0115","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1097\/CCM.0b013e31823dae23","article-title":"Systemic administration of autologous adipose-derived mesenchymal stem cells alleviates hepatic ischemia\u2013reperfusion injury in rats","volume":"40","author":"Sun","year":"2012","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.scr.2013.07.003_bb0120","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1089\/107632701300062859","article-title":"Multilineage cells from human adipose tissue: implications for cell-based therapies","volume":"7","author":"Zuk","year":"2001","journal-title":"Tissue Eng."}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506113000858?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506113000858?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,14]],"date-time":"2018-10-14T10:29:37Z","timestamp":1539512977000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506113000858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S1873506113000858"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2013.07.003","relation":{},"ISSN":["1873-5061"],"issn-type":[{"value":"1873-5061","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of adipose tissue-mesenchymal stem cell transplantation in rats with acetaminophen liver injury","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2013.07.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}