{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:12:51Z","timestamp":1762506771885,"version":"3.40.5"},"reference-count":13,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T00:00:00Z","timestamp":1459987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.scr.2016.04.007","type":"journal-article","created":{"date-parts":[[2016,4,12]],"date-time":"2016-04-12T12:48:40Z","timestamp":1460465320000},"page":"677-681","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["GABP is necessary for stem\/progenitor cell maintenance and myeloid differentiation in human hematopoiesis and chronic myeloid leukemia"],"prefix":"10.1016","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0393-8569","authenticated-orcid":false,"given":"Georgi","family":"Manukjan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Ripperger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letizia","family":"Venturini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Stadler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gudrun","family":"G\u00f6hring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Schambach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigitte","family":"Schlegelberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris","family":"Steinemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.scr.2016.04.007_bb0005","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1038\/sj.leu.2401566","article-title":"Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR","volume":"13","author":"Emig","year":"1999","journal-title":"Leukemia"},{"key":"10.1016\/j.scr.2016.04.007_bb0010","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1182\/blood-2006-01-0092","article-title":"Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results","volume":"108","author":"Hughes","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.scr.2016.04.007_bb0015","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.exphem.2015.05.011","article-title":"Expression of the ETS transcription factor GABPalpha is positively correlated to the BCR-ABL1\/ABL1 ratio in CML patients and affects imatinib sensitivity in vitro","volume":"43","author":"Manukjan","year":"2015","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.scr.2016.04.007_bb0020","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1042\/CS20040336","article-title":"Chronic myeloid leukaemia: stem cell derived but progenitor cell driven","volume":"109","author":"Marley","year":"2005","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.scr.2016.04.007_bb0025","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.cell.2008.01.025","article-title":"Hematopoiesis: an evolving paradigm for stem cell biology","volume":"132","author":"Orkin","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.scr.2016.04.007_bb0030","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.bbagrm.2015.07.005","article-title":"The heteromeric transcription factor GABP activates the ITGAM\/CD11b promoter and induces myeloid differentiation","volume":"1849","author":"Ripperger","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.scr.2016.04.007_bb0035","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.bcmd.2003.09.005","article-title":"GA-binding protein transcription factor: a review of GABP as an integrator of intracellular signaling and protein\u2013protein interactions","volume":"32","author":"Rosmarin","year":"2004","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.scr.2016.04.007_bb0045","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/sj.leu.2403241","article-title":"JAK\/STAT, Raf\/MEK\/ERK, PI3K\/Akt and BCR-ABL in cell cycle progression and leukemogenesis","volume":"18","author":"Steelman","year":"2004","journal-title":"Leukemia"},{"key":"10.1016\/j.scr.2016.04.007_bb0050","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1182\/blood-2010-07-298802","article-title":"GABP transcription factor is required for myeloid differentiation, in part, through its control of Gfi-1 expression","volume":"118","author":"Yang","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.scr.2016.04.007_bb0055","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1073\/pnas.1212904110","article-title":"GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2","volume":"110","author":"Yang","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scr.2016.04.007_bb0060","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1182\/blood-2010-09-306563","article-title":"GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem\/progenitor cells","volume":"117","author":"Yu","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.scr.2016.04.007_bb0065","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.stem.2012.05.021","article-title":"Targeting tetramer-forming GABPbeta isoforms impairs self-renewal of hematopoietic and leukemic stem cells","volume":"11","author":"Yu","year":"2012","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.scr.2016.04.007_bb0070","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1182\/blood-2006-12-060814","article-title":"Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells","volume":"110","author":"Zhang","year":"2007","journal-title":"Blood"}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506116300186?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506116300186?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T07:57:13Z","timestamp":1536825433000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506116300186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["S1873506116300186"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2016.04.007","relation":{},"ISSN":["1873-5061"],"issn-type":[{"type":"print","value":"1873-5061"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GABP is necessary for stem\/progenitor cell maintenance and myeloid differentiation in human hematopoiesis and chronic myeloid leukemia","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2016.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}