{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T13:18:02Z","timestamp":1780406282885,"version":"3.54.1"},"reference-count":74,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,29]],"date-time":"2016-07-29T00:00:00Z","timestamp":1469750400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Fondazione Roma"},{"DOI":"10.13039\/501100004271","name":"Sapienza University of Rome","doi-asserted-by":"publisher","award":["C26A1429M2"],"award-info":[{"award-number":["C26A1429M2"]}],"id":[{"id":"10.13039\/501100004271","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.scr.2016.07.010","type":"journal-article","created":{"date-parts":[[2016,7,31]],"date-time":"2016-07-31T12:29:23Z","timestamp":1469968163000},"page":"342-351","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots"],"prefix":"10.1016","volume":"17","author":[{"given":"Camilla","family":"Siciliano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Bordin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isotta","family":"Chimenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Cassiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilenia","family":"Gatto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Mangino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Coccia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selenia","family":"Miglietta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Bastianelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Petrozza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Calogero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Frati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"De Falco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scr.2016.07.010_bb0005","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1182\/blood-2004-04-1559","article-title":"Human mesenchymal stem cells modulate allogeneic immune cell responses","volume":"105","author":"Aggarwal","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.scr.2016.07.010_bb0010","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.carpath.2012.07.006","article-title":"Mediastinal adipose tissue expresses a pathogenic profile of 11 beta-hydroxysteroid dehydrogenase Type 1, glucocorticoid receptor, and CD68 in patients with coronary artery disease","volume":"22","author":"Atalar","year":"2013","journal-title":"Cardiovasc. Pathol. Off. J. Soc. Cardiovasc. Pathol."},{"key":"10.1016\/j.scr.2016.07.010_bb0020","doi-asserted-by":"crossref","first-page":"e36569","DOI":"10.1371\/journal.pone.0036569","article-title":"Functional differences in visceral and subcutaneous fat pads originate from differences in the adipose stem cell","volume":"7","author":"Baglioni","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.scr.2016.07.010_bb0025","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1159\/000354061","article-title":"Platelet lysate as replacement for fetal bovine serum in mesenchymal stromal cell cultures","volume":"40","author":"Bieback","year":"2013","journal-title":"Transfus. Med. Hemother."},{"key":"10.1016\/j.scr.2016.07.010_bb0030","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1172\/JCI32239","article-title":"Angiogenesis modulates adipogenesis and obesity","volume":"117","author":"Cao","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.scr.2016.07.010_bb9000","first-page":"84","article-title":"GMP-grade platelet lysate enhances proliferation and migration of tenon fibroblasts","volume":"8","author":"Carducci","year":"2016","journal-title":"Front. Biosci. (Elite Ed.)"},{"key":"10.1016\/j.scr.2016.07.010_bb0035","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/ncb2922","article-title":"Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source","volume":"16","author":"Chau","year":"2014","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.scr.2016.07.010_bb0040","doi-asserted-by":"crossref","first-page":"e66","DOI":"10.1038\/nutd.2013.6","article-title":"Human mediastinal adipose tissue displays certain characteristics of brown fat","volume":"3","author":"Cheung","year":"2013","journal-title":"Nutr. Diabetes"},{"key":"10.1016\/j.scr.2016.07.010_bb0045","first-page":"81","article-title":"Adipose tissue, inflammation and endothelial dysfunction","volume":"58","author":"Chudek","year":"2006","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.scr.2016.07.010_bb0050","doi-asserted-by":"crossref","first-page":"476","DOI":"10.4161\/epi.5.6.12517","article-title":"Programming differentiation potential in mesenchymal stem cells","volume":"5","author":"Collas","year":"2010","journal-title":"Epigenetics"},{"key":"10.1016\/j.scr.2016.07.010_bb0055","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1161\/CIRCULATIONAHA.108.793208","article-title":"Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo","volume":"119","author":"Conrad","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.scr.2016.07.010_bb0060","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s10561-012-9325-1","article-title":"A standardized laboratory and surgical method for in vitro culture isolation and expansion of primary human Tenon's fibroblasts","volume":"14","author":"De Falco","year":"2013","journal-title":"Cell Tissue Bank."},{"key":"10.1016\/j.scr.2016.07.010_bb0065","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1080\/07853890500383895","article-title":"Is visceral obesity the cause of the metabolic syndrome?","volume":"38","author":"Despres","year":"2006","journal-title":"Ann. Med."},{"key":"10.1016\/j.scr.2016.07.010_bb0070","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement","volume":"8","author":"Dominici","year":"2006","journal-title":"Cytotherapy"},{"key":"10.1016\/j.scr.2016.07.010_bb0075","doi-asserted-by":"crossref","first-page":"5646384","DOI":"10.1155\/2016\/5646384","article-title":"Human mesenchymal stromal cells from different sources diverge in their expression of cell surface proteins and display distinct differentiation patterns","volume":"2016","author":"Elahi","year":"2016","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.scr.2016.07.010_bb0080","doi-asserted-by":"crossref","first-page":"513948","DOI":"10.1155\/2010\/513948","article-title":"Release of inflammatory mediators by human adipose tissue is enhanced in obesity and primarily by the nonfat cells: a review","volume":"2010","author":"Fain","year":"2010","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.scr.2016.07.010_bb0085","series-title":"Stem Cells and Cloning : Advances and Applications","first-page":"149","article-title":"From bench to bedside: use of human adipose-derived stem cells","volume":"Vol. 8","author":"Feisst","year":"2015"},{"key":"10.1016\/j.scr.2016.07.010_bb0090","first-page":"381","article-title":"Osteogenesis in transplants of bone marrow cells","volume":"16","author":"Friedenstein","year":"1966","journal-title":"J. Embryol. Exp. Morpholog."},{"key":"10.1016\/j.scr.2016.07.010_bb0095","first-page":"267","article-title":"Fibroblast precursors in normal and irradiated mouse hematopoietic organs","volume":"4","author":"Friedenstein","year":"1976","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.scr.2016.07.010_bb0100","doi-asserted-by":"crossref","first-page":"6676","DOI":"10.1073\/pnas.0601752103","article-title":"Evidence for a role of developmental genes in the origin of obesity and body fat distribution","volume":"103","author":"Gesta","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scr.2016.07.010_bb0105","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.cell.2007.10.004","article-title":"Developmental origin of fat: tracking obesity to its source","volume":"131","author":"Gesta","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.scr.2016.07.010_bb0110","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.yexcr.2015.07.031","article-title":"Different origin of adipogenic stem cells influences the response to antiretroviral drugs","volume":"337","author":"Gibellini","year":"2015","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.scr.2016.07.010_bb0115","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1161\/01.RES.0000265074.83288.09","article-title":"Adipose-derived stem cells for regenerative medicine","volume":"100","author":"Gimble","year":"2007","journal-title":"Circ. Res."},{"key":"10.1016\/j.scr.2016.07.010_bb0120","doi-asserted-by":"crossref","first-page":"E1523","DOI":"10.1073\/pnas.1120349109","article-title":"Cellular mechanical properties reflect the differentiation potential of adipose-derived mesenchymal stem cells","volume":"109","author":"Gonzalez-Cruz","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scr.2016.07.010_bb0125","doi-asserted-by":"crossref","first-page":"461S","DOI":"10.1093\/ajcn\/83.2.461S","article-title":"Obesity and the role of adipose tissue in inflammation and metabolism","volume":"83","author":"Greenberg","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.scr.2016.07.010_bb0130","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1177\/1534734614534977","article-title":"Angiogenic effect of mesenchymal stem cells as a therapeutic target for enhancing diabetic wound healing","volume":"13","author":"Gu","year":"2014","journal-title":"Int. J. Low. Extrem. Wounds"},{"key":"10.1016\/j.scr.2016.07.010_bb0135","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.biomaterials.2015.08.053","article-title":"Adipose-derived stromal cells mediate in vivo adipogenesis, angiogenesis and inflammation in decellularized adipose tissue bioscaffolds","volume":"72","author":"Han","year":"2015","journal-title":"Biomaterials"},{"key":"10.1016\/j.scr.2016.07.010_bb0140","doi-asserted-by":"crossref","first-page":"3946","DOI":"10.1245\/s10434-015-4432-4","article-title":"Low visceral fat content is associated with poor prognosis in a database of 507 upper gastrointestinal cancers","volume":"22","author":"Harada","year":"2015","journal-title":"Ann. Surg. Oncol."},{"key":"10.1016\/j.scr.2016.07.010_bb0145","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1038\/labinvest.3780386","article-title":"Co-expression of VEGF-C and its receptors, VEGFR-2 and VEGFR-3, in endothelial cells of lymphangioma. Implication in autocrine or paracrine regulation of lymphangioma","volume":"81","author":"Huang","year":"2001","journal-title":"Lab. Investig."},{"key":"10.1016\/j.scr.2016.07.010_bb0150","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1479-5876-12-28","article-title":"Pathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cells","volume":"12","author":"Iudicone","year":"2014","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.scr.2016.07.010_bb0155","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1161\/CIRCRESAHA.116.303614","article-title":"Use of mesenchymal stem cells for therapy of cardiac disease","volume":"116","author":"Karantalis","year":"2015","journal-title":"Circ. Res."},{"key":"10.1016\/j.scr.2016.07.010_bb0160","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s00403-009-0951-9","article-title":"Protective role of adipose-derived stem cells and their soluble factors in photoaging","volume":"301","author":"Kim","year":"2009","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.scr.2016.07.010_bb0165","doi-asserted-by":"crossref","first-page":"E268","DOI":"10.1210\/jc.2010-1681","article-title":"Altered autophagy in human adipose tissues in obesity","volume":"96","author":"Kovsan","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.scr.2016.07.010_bb0170","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1634\/stemcells.2005-0008","article-title":"Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells","volume":"24","author":"Krampera","year":"2006","journal-title":"Stem Cells"},{"key":"10.1016\/j.scr.2016.07.010_bb0175","doi-asserted-by":"crossref","first-page":"e215","DOI":"10.1038\/emm.2016.5","article-title":"Heterogeneity of white adipose tissue: molecular basis and clinical implications","volume":"48","author":"Kwok","year":"2016","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.scr.2016.07.010_bb0180","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.vph.2014.06.004","article-title":"Multiple paracrine factors secreted by mesenchymal stem cells contribute to angiogenesis","volume":"63","author":"Kwon","year":"2014","journal-title":"Vasc. Pharmacol."},{"key":"10.1016\/j.scr.2016.07.010_bb0185","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1136\/bmj.289.6454.1257","article-title":"Distribution of adipose tissue and risk of cardiovascular disease and death: a 12year follow up of participants in the population study of women in Gothenburg, Sweden","volume":"289","author":"Lapidus","year":"1984","journal-title":"Br. Med. J. (Clin. Res. Ed.)"},{"key":"10.1016\/j.scr.2016.07.010_bb0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mam.2012.10.001","article-title":"Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications","volume":"34","author":"Lee","year":"2013","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.scr.2016.07.010_bb0195","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/nm0204-126","article-title":"Inflamed about obesity","volume":"10","author":"Lehrke","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.scr.2016.07.010_bb0200","doi-asserted-by":"crossref","first-page":"695","DOI":"10.3892\/ijmm.2014.1821","article-title":"Comprehensive characterization of four different populations of human mesenchymal stem cells as regards their immune properties, proliferation and differentiation","volume":"34","author":"Li","year":"2014","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.scr.2016.07.010_bb0205","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ijcard.2013.08.077","article-title":"Ectopic fat and cardiometabolic and vascular risk","volume":"169","author":"Lim","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.scr.2016.07.010_bb0210","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1186\/1756-0500-7-552","article-title":"Characterization of adipose-derived stem cells of anatomical region from mice","volume":"7","author":"Luna","year":"2014","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.scr.2016.07.010_bb0215","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1152\/physiol.00048.2015","article-title":"Transcriptional dysregulation of adipose tissue autophagy in obesity","volume":"31","author":"Maixner","year":"2016","journal-title":"Physiology"},{"key":"10.1016\/j.scr.2016.07.010_bb0220","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.cryobiol.2015.07.003","article-title":"Mesenchymal stromal cells derived from various tissues: biological, clinical and cryopreservation aspects","volume":"71","author":"Marquez-Curtis","year":"2015","journal-title":"Cryobiology"},{"key":"10.1016\/j.scr.2016.07.010_bb0225","doi-asserted-by":"crossref","first-page":"4619","DOI":"10.1182\/blood-2003-11-3909","article-title":"Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation","volume":"103","author":"Meisel","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.scr.2016.07.010_bb0230","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.bbalip.2016.06.010","article-title":"Regulation of adipogenesis by paracrine factors from adipose stromal-vascular fraction - a link to fat depot-specific differences","volume":"1861","author":"Meissburger","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.scr.2016.07.010_bb0235","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3109\/07357907.2013.861472","article-title":"Axitinib affects cell viability and migration of a primary foetal lung adenocarcinoma culture","volume":"32","author":"Menna","year":"2014","journal-title":"Cancer Investig."},{"key":"10.1016\/j.scr.2016.07.010_bb0240","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/j.1550-8528.1997.tb00648.x","article-title":"Relationship of anterior and posterior subcutaneous abdominal fat to insulin sensitivity in nondiabetic men","volume":"5","author":"Misra","year":"1997","journal-title":"Obes. Res."},{"key":"10.1016\/j.scr.2016.07.010_bb0245","doi-asserted-by":"crossref","first-page":"80","DOI":"10.5045\/br.2015.50.2.80","article-title":"Down-regulation of the autophagy gene, ATG7, protects bone marrow-derived mesenchymal stem cells from stressful conditions","volume":"50","author":"Molaei","year":"2015","journal-title":"Blood Res."},{"key":"10.1016\/j.scr.2016.07.010_bb0250","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1172\/JCI27280","article-title":"Inflamed fat: what starts the fire?","volume":"116","author":"Neels","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.scr.2016.07.010_bb0255","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1532\/IJH97.07041","article-title":"Mesenchymal stem cells for the treatment of heart failure","volume":"86","author":"Ohnishi","year":"2007","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.scr.2016.07.010_bb0260","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1080\/01913120601169477","article-title":"Ultrastructural characteristics of human mesenchymal stromal (stem) cells derived from bone marrow and term placenta","volume":"31","author":"Pasquinelli","year":"2007","journal-title":"Ultrastruct. Pathol."},{"key":"10.1016\/j.scr.2016.07.010_bb0265","doi-asserted-by":"crossref","first-page":"507","DOI":"10.3727\/096368912X636849","article-title":"Putative population of adipose-derived stem cells isolated from mediastinal tissue during cardiac surgery","volume":"22","author":"Patel","year":"2013","journal-title":"Cell Transplant."},{"key":"10.1016\/j.scr.2016.07.010_bb0270","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s00125-007-0841-7","article-title":"Fat depot-related differences in gene expression, adiponectin secretion, and insulin action and signalling in human adipocytes differentiated in vitro from precursor stromal cells","volume":"51","author":"Perrini","year":"2008","journal-title":"Diabetologia"},{"key":"10.1016\/j.scr.2016.07.010_bb0275","doi-asserted-by":"crossref","first-page":"3785","DOI":"10.2337\/db14-0385","article-title":"Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications","volume":"63","author":"Pinnick","year":"2014","journal-title":"Diabetes"},{"key":"10.1016\/j.scr.2016.07.010_bb0280","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1161\/CIRCULATIONAHA.107.710509","article-title":"Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study","volume":"116","author":"Pou","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.scr.2016.07.010_bb0285","doi-asserted-by":"crossref","first-page":"a015339","DOI":"10.1101\/cshperspect.a015339","article-title":"Immunology and skin in health and disease","volume":"4","author":"Richmond","year":"2014","journal-title":"Cold Spring Harb Perspect. Med."},{"key":"10.1016\/j.scr.2016.07.010_bb0290","doi-asserted-by":"crossref","first-page":"34475","DOI":"10.18632\/oncotarget.5922","article-title":"Characterization of adipose-derived stem cells from subcutaneous and visceral adipose tissues and their function in breast cancer cells","volume":"6","author":"Ritter","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.scr.2016.07.010_bb0295","doi-asserted-by":"crossref","first-page":"206","DOI":"10.5966\/sctm.2013-0125","article-title":"Comparison of human adipose-derived stem cells isolated from subcutaneous, omental, and intrathoracic adipose tissue depots for regenerative applications","volume":"3","author":"Russo","year":"2014","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.scr.2016.07.010_bb0300","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1210\/er.2005-0022","article-title":"Role of adipose tissue as an inflammatory organ in human diseases","volume":"27","author":"Schaffler","year":"2006","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.scr.2016.07.010_bb0305","doi-asserted-by":"crossref","first-page":"120949","DOI":"10.1155\/2015\/120949","article-title":"The role of adipose-derived stem cells in breast cancer progression and metastasis","volume":"2015","author":"Schweizer","year":"2015","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.scr.2016.07.010_bb0310","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/j.echo.2011.06.013","article-title":"Pericardial rather than epicardial fat is a cardiometabolic risk marker: an MRI vs echo study","volume":"24","author":"Sicari","year":"2011","journal-title":"J. Am. Soc. Echocardiogr. Off. Publ. Am. Soc. Echocardiogr."},{"key":"10.1016\/j.scr.2016.07.010_bb0315","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s10616-013-9667-y","article-title":"Optimization of the isolation and expansion method of human mediastinal-adipose tissue derived mesenchymal stem cells with virally inactivated GMP-grade platelet lysate","volume":"67","author":"Siciliano","year":"2015","journal-title":"Cytotechnology"},{"key":"10.1016\/j.scr.2016.07.010_bb0325","first-page":"162439","article-title":"The potential of GMP-Compliant platelet lysate to induce a permissive state for cardiovascular transdifferentiation in human mediastinal adipose tissue-derived mesenchymal stem cells","author":"Siciliano","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.scr.2016.07.010_bb0330","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.3727\/096368914X685771","article-title":"Cardiosphere conditioned media influence the plasticity of human mediastinal adipose tissue-derived mesenchymal stem cells","volume":"24","author":"Siciliano","year":"2015","journal-title":"Cell Transplant."},{"key":"10.1016\/j.scr.2016.07.010_bb0335","first-page":"3329","article-title":"Autophagy regulates adipose mass and differentiation in mice","volume":"119","author":"Singh","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.scr.2016.07.010_bb0340","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1111\/j.1464-5491.2011.03503.x","article-title":"Impact of increased visceral and cardiac fat on cardiometabolic risk and disease","volume":"29","author":"Sironi","year":"2012","journal-title":"Diabet. Med. J. Br. Diabet. Assoc."},{"key":"10.1016\/j.scr.2016.07.010_bb0345","first-page":"S58","article-title":"Human mesenchymal stem cells as a tool for joint repair in rheumatoid arthritis","volume":"33","author":"Tanaka","year":"2015","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.scr.2016.07.010_bb0350","first-page":"R1286","article-title":"Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes","volume":"282","author":"Tchkonia","year":"2002","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"key":"10.1016\/j.scr.2016.07.010_bb0355","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/cbf.1591","article-title":"Characterization and comparison of adipose tissue-derived cells from human subcutaneous and omental adipose tissues","volume":"27","author":"Toyoda","year":"2009","journal-title":"Cell Biochem. Funct."},{"key":"10.1016\/j.scr.2016.07.010_bb0360","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1079\/BJN20041213","article-title":"Adipokines: inflammation and the pleiotropic role of white adipose tissue","volume":"92","author":"Trayhurn","year":"2004","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.scr.2016.07.010_bb0365","first-page":"203","article-title":"Regulation of angiogenesis via vascular endothelial growth factor receptors","volume":"60","author":"Veikkola","year":"2000","journal-title":"Cancer Res."},{"key":"10.1016\/j.scr.2016.07.010_bb0370","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1111\/j.1440-1681.2011.05596.x","article-title":"Regulation of stem cell differentiation in adipose tissue by chronic inflammation","volume":"38","author":"Ye","year":"2011","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.scr.2016.07.010_bb0375","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1016\/j.biochi.2013.05.010","article-title":"Mesenchymal stem cell secretome and regenerative therapy after cancer","volume":"95","author":"Zimmerlin","year":"2013","journal-title":"Biochimie"}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506116300988?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506116300988?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,11]],"date-time":"2019-09-11T20:09:33Z","timestamp":1568232573000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506116300988"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":74,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S1873506116300988"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2016.07.010","relation":{},"ISSN":["1873-5061"],"issn-type":[{"value":"1873-5061","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2016.07.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}