{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T03:51:22Z","timestamp":1793937082718,"version":"4.8.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T00:00:00Z","timestamp":1472169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"JSPS","award":["21380184"],"award-info":[{"award-number":["21380184"]}]},{"name":"JSPS","award":["24580435"],"award-info":[{"award-number":["24580435"]}]},{"name":"MUIIR"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.scr.2016.08.016","type":"journal-article","created":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T08:02:52Z","timestamp":1473235372000},"page":"318-329","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Isolation of adult pituitary stem\/progenitor cell clusters located in the parenchyma of the rat anterior lobe"],"prefix":"10.1016","volume":"17","author":[{"given":"Saishu","family":"Yoshida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoto","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Ueharu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Kanno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Horiguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takako","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukio","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scr.2016.08.016_bb0005","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1634\/stemcells.2007-0448","article-title":"Expression of multiple chondroitin\/dermatan sulfotransferases in the neurogenic regions of the embryonic and adult central nervous system implies that complex chondroitin sulfates have a role in neural stem cell maintenance","volume":"26","author":"Akita","year":"2008","journal-title":"Stem Cells"},{"key":"10.1016\/j.scr.2016.08.016_bb0010","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.stem.2013.07.004","article-title":"Sox2(+) stem\/progenitor cells in the adult mouse pituitary support organ homeostasis and have tumor-inducing potential","volume":"13","author":"Andoniadou","year":"2013","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.scr.2016.08.016_bb0015","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jdermsci.2012.02.007","article-title":"Multi-layered environmental regulation on the homeostasis of stem cells: the saga of hair growth and alopecia","volume":"66","author":"Chen","year":"2012","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.scr.2016.08.016_bb0020","doi-asserted-by":"crossref","first-page":"3985","DOI":"10.1210\/en.2005-0185","article-title":"The adult pituitary contains a cell population displaying stem\/progenitor cell and early embryonic characteristics","volume":"146","author":"Chen","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.scr.2016.08.016_bb0025","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.1210\/me.2006-0293","article-title":"The notch signaling system is present in the postnatal pituitary: marked expression and regulatory activity in the newly discovered side population","volume":"20","author":"Chen","year":"2006","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.scr.2016.08.016_bb0030","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1002\/stem.51","article-title":"Pituitary progenitor cells tracked down by side population dissection","volume":"27","author":"Chen","year":"2009","journal-title":"Stem Cells"},{"key":"10.1016\/j.scr.2016.08.016_bb0035","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00441-013-1713-8","article-title":"Coxsackievirus and adenovirus receptor-positive cells compose the putative stem\/progenitor cell niches in the marginal cell layer and parenchyma of the rat anterior pituitary","volume":"354","author":"Chen","year":"2013","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.scr.2016.08.016_bb0040","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S1046-2023(03)00032-X","article-title":"Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures","volume":"30","author":"Debnath","year":"2003","journal-title":"Methods"},{"key":"10.1016\/j.scr.2016.08.016_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2826.2007.01616.x","article-title":"Paracrinicity: the story of 30years of cellular pituitary crosstalk","volume":"20","author":"Denef","year":"2008","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.scr.2016.08.016_bb0050","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1073\/pnas.0707886105","article-title":"SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland","volume":"105","author":"Fauquier","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.scr.2016.08.016_bb0055","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.1089\/scd.2012.0290","article-title":"Regenerative capacity of the adult pituitary: multiple mechanisms of lactotroph restoration after transgenic ablation","volume":"21","author":"Fu","year":"2012","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.scr.2016.08.016_bb0060","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1210\/en.2012-1152","article-title":"The adult pituitary shows stem\/progenitor cell activation in response to injury and is capable of regeneration","volume":"153","author":"Fu","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.scr.2016.08.016_bb0065","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1016\/j.bbagen.2014.01.010","article-title":"Extracellular matrix: a dynamic microenvironment for stem cell niche","volume":"1840","author":"Gattazzo","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.scr.2016.08.016_bb0070","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1089\/scd.2011.0496","article-title":"Activated phenotype of the pituitary stem\/progenitor cell compartment during the early-postnatal maturation phase of the gland","volume":"21","author":"Gremeaux","year":"2012","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.scr.2016.08.016_bb0075","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1523\/JNEUROSCI.16-03-01091.1996","article-title":"Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor","volume":"16","author":"Gritti","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.scr.2016.08.016_bb0080","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1083\/jcb.200904118","article-title":"Drosophila glypicans regulate the germline stem cell niche","volume":"187","author":"Hayashi","year":"2009","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.scr.2016.08.016_bb0085","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00441-014-1861-5","article-title":"PRRX1 and PRRX2 distinctively participate in pituitary organogenesis and cell supply system","volume":"357","author":"Higuchi","year":"2014","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.scr.2016.08.016_bb0090","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1210\/en.2006-1390","article-title":"Generation of transgenic rats expressing green fluorescent protein in S-100beta-producing pituitary folliculo-stellate cells and brain astrocytes","volume":"148","author":"Itakura","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.scr.2016.08.016_bb0095","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1111\/j.1349-7006.2008.00885.x","article-title":"Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progression","volume":"99","author":"Itano","year":"2008","journal-title":"Cancer Sci."},{"key":"10.1016\/j.scr.2016.08.016_bb0100","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1210\/en.2004-1209","article-title":"Nestin-immunoreactive cells in rat pituitary are neither hormonal nor typical folliculo-stellate cells","volume":"146","author":"Krylyshkina","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.scr.2016.08.016_bb0105","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1677\/joe.0.1740147","article-title":"Physiological implications of pituitary trophic activity","volume":"174","author":"Levy","year":"2002","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.scr.2016.08.016_bb0110","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1365-2826.2007.01621.x","article-title":"Stem cells, hormones and pituitary adenomas","volume":"20","author":"Levy","year":"2008","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.scr.2016.08.016_bb0115","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1046\/j.1365-2826.1998.00191.x","article-title":"Anterior pituitary cell population control: basal cell turnover and the effects of adrenalectomy and dexamethasone treatment","volume":"10","author":"Nolan","year":"1998","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.scr.2016.08.016_bb0120","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.stem.2011.04.007","article-title":"Eyes wide open: a critical review of sphere-formation as an assay for stem cells","volume":"8","author":"Pastrana","year":"2011","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.scr.2016.08.016_bb0125","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1126\/science.1553558","article-title":"Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system","volume":"255","author":"Reynolds","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.scr.2016.08.016_bb0130","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.stem.2013.07.006","article-title":"Mobilized adult pituitary stem cells contribute to endocrine regeneration in response to physiological demand","volume":"13","author":"Rizzoti","year":"2013","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.scr.2016.08.016_bb0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0040-8166(94)90078-7","article-title":"Immunohistochemical study of the post-natal development of the folliculo-stellate cells in the rat anterior pituitary gland","volume":"26","author":"Soji","year":"1994","journal-title":"Tissue Cell"},{"key":"10.1016\/j.scr.2016.08.016_bb0140","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature10637","article-title":"Self-formation of functional adenohypophysis in three-dimensional culture","volume":"480","author":"Suga","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.scr.2016.08.016_bb0145","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.stem.2010.11.029","article-title":"Hair follicle stem cells provide a functional niche for melanocyte stem cells","volume":"8","author":"Tanimura","year":"2011","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.scr.2016.08.016_bb0150","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.mce.2013.08.018","article-title":"Pituitary stem cells: where do we stand?","volume":"385","author":"Vankelecom","year":"2014","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.scr.2016.08.016_bb0155","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.bbrc.2009.05.027","article-title":"PROP1 coexists with SOX2 and induces PIT1-commitment cells","volume":"385","author":"Yoshida","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.scr.2016.08.016_bb0160","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1111\/j.1365-2826.2011.02198.x","article-title":"Significant quantitative and qualitative transition in pituitary stem\/progenitor cells occurs during the postnatal development of the rat anterior pituitary","volume":"23","author":"Yoshida","year":"2011","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.scr.2016.08.016_bb0165","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s00441-014-2054-y","article-title":"Localization of a juxtacrine factor ephrin-B2 in the pituitary stem\/progenitor cell niches throughout life","volume":"359","author":"Yoshida","year":"2015","journal-title":"Cell Tissue Res."}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506116301155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506116301155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T03:11:48Z","timestamp":1718766708000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506116301155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S1873506116301155"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2016.08.016","relation":{},"ISSN":["1873-5061"],"issn-type":[{"value":"1873-5061","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Isolation of adult pituitary stem\/progenitor cell clusters located in the parenchyma of the rat anterior lobe","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2016.08.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}