{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T21:36:59Z","timestamp":1774042619321,"version":"3.50.1"},"reference-count":5,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["2017\/27\/N\/NZ3\/00991"],"award-info":[{"award-number":["2017\/27\/N\/NZ3\/00991"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.scr.2023.103046","type":"journal-article","created":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T11:49:39Z","timestamp":1676288979000},"page":"103046","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Generation of miR-15a\/16-1 cluster-deficient human induced pluripotent stem cell line (DMBi001-A-2) using CRISPR\/Cas9 gene editing"],"prefix":"10.1016","volume":"68","author":[{"given":"Jacek","family":"St\u0119pniewski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mateusz","family":"Je\u017c","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4500-0405","authenticated-orcid":false,"given":"J\u00f3zef","family":"Dulak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"51","key":"10.1016\/j.scr.2023.103046_b0005","doi-asserted-by":"crossref","first-page":"19740","DOI":"10.1074\/jbc.RA118.003935","article-title":"Macrophage migration inhibitory factor regulates mitochondrial dynamics and cell growth of human cancer cell lines through CD74\u2013NF-\u03baB signaling","volume":"293","author":"De","year":"2018","journal-title":"J. Biol. Chem."},{"issue":"8","key":"10.1016\/j.scr.2023.103046_b0010","doi-asserted-by":"crossref","first-page":"e242","DOI":"10.1002\/ctm2.242","article-title":"mir15a\/mir16-1 cluster and its novel targeting molecules negatively regulate cardiac hypertrophy","volume":"10","author":"Guo","year":"2020","journal-title":"Clin. Trans. Med."},{"key":"10.1016\/j.scr.2023.103046_b0015","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1006\/jmcc.1996.0163","article-title":"Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development","volume":"28","author":"Li","year":"1996","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"6","key":"10.1016\/j.scr.2023.103046_b0020","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1161\/CIRCRESAHA.111.248880","article-title":"The miR-15 family regulates post-natal mitotic arrest of cardiomyocytes","volume":"109","author":"Porrello","year":"2011","journal-title":"Circ Res."},{"issue":"12","key":"10.1016\/j.scr.2023.103046_b0025","doi-asserted-by":"crossref","first-page":"578","DOI":"10.3390\/biomedicines8120578","article-title":"Human induced pluripotent stem cell-derived cardiomyocytes, in contrast to adipose tissue-derived stromal cells, efficiently improve heart function in murine model of myocardial infarction","volume":"8","author":"St\u0119pniewski","year":"2020","journal-title":"Biomedicines"}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506123000326?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506123000326?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T11:37:32Z","timestamp":1761737852000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506123000326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":5,"alternative-id":["S1873506123000326"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2023.103046","relation":{},"ISSN":["1873-5061"],"issn-type":[{"value":"1873-5061","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Generation of miR-15a\/16-1 cluster-deficient human induced pluripotent stem cell line (DMBi001-A-2) using CRISPR\/Cas9 gene editing","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2023.103046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103046"}}