{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T16:19:32Z","timestamp":1780417172170,"version":"3.54.1"},"reference-count":9,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014464","name":"Australian Genome Research Facility","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014464","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["10915693"],"award-info":[{"award-number":["10915693"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.scr.2024.103367","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T05:05:54Z","timestamp":1709096754000},"page":"103367","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["An iPSC line (FINi003-A) from a male with late-onset developmental and epileptic encephalopathy caused by a heterozygous p.E1211K variant in the SCN2A gene encoding the voltage-gated sodium channel Nav1.2"],"prefix":"10.1016","volume":"76","author":[{"given":"Dmitry A.","family":"Ovchinnikov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Jong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Cuddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Dalby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orrin","family":"Devinsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saul","family":"Mullen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Snezana","family":"Maljevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Petrou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scr.2024.103367_b0005","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/s42003-022-03454-1","article-title":"Functional correlates of clinical phenotype and severity in recurrent SCN2A variants","volume":"5","author":"Berecki","year":"2022","journal-title":"Commun Biol"},{"key":"10.1016\/j.scr.2024.103367_b0010","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1212\/WNL.0000000000001926","article-title":"SCN2A encephalopathy: a major cause of epilepsy of infancy with migrating focal seizures","volume":"85","author":"Howell","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.scr.2024.103367_b0015","doi-asserted-by":"crossref","unstructured":"Mason ER, Wu F, Patel RR, Xiao Y, Cannon SC, Cummins TR. 2019. Resurgent and Gating Pore Currents Induced by De Novo SCN2A Epilepsy Mutations. eNeuro 6.","DOI":"10.1523\/ENEURO.0141-19.2019"},{"key":"10.1016\/j.scr.2024.103367_b0020","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1212\/WNL.0b013e3181b9cebc","article-title":"De novo mutations of voltage-gated sodium channel alphaII gene SCN2A in intractable epilepsies","volume":"73","author":"Ogiwara","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.scr.2024.103367_b0025","article-title":"Reprogramming fibroblasts and mononuclear blood cells into iPSCs using Sendai virus","author":"Ovchinnikov","year":"2021","journal-title":"Protocols.io"},{"key":"10.1016\/j.scr.2024.103367_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.scr.2023.103179","article-title":"Generation of an iPSC line (FINi001-a) from a girl with developmental and epileptic encephalopathy due to a heterozygous gain-of-function p. R1882Q variant in the voltage-gated sodium channel Na(v)1.2 protein encoded by the SCN2A gene","volume":"71","author":"Ovchinnikov","year":"2023","journal-title":"Stem Cell Res"},{"key":"10.1016\/j.scr.2024.103367_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.scr.2023.103211","article-title":"Generation of the iPSC line FINi002-a from a male parkinson's disease patient carrying compound heterozygous mutations in the PRKN gene","volume":"73","author":"Pavan","year":"2023","journal-title":"Stem Cell Res"},{"key":"10.1016\/j.scr.2024.103367_b0040","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.braindev.2011.09.016","article-title":"Clinical spectrum of SCN2A mutations","volume":"34","author":"Shi","year":"2012","journal-title":"Brain Dev"},{"key":"10.1016\/j.scr.2024.103367_b0045","article-title":"SCN2A-related epilepsy: the phenotypic Spectrum","volume":"15","author":"Zeng","year":"2022","journal-title":"Treatment and Prognosis. Front Mol Neurosci"}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506124000655?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506124000655?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T23:47:51Z","timestamp":1762559271000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506124000655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":9,"alternative-id":["S1873506124000655"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2024.103367","relation":{},"ISSN":["1873-5061"],"issn-type":[{"value":"1873-5061","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An iPSC line (FINi003-A) from a male with late-onset developmental and epileptic encephalopathy caused by a heterozygous p.E1211K variant in the SCN2A gene encoding the voltage-gated sodium channel Nav1.2","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2024.103367","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103367"}}