{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T08:27:37Z","timestamp":1776846457254,"version":"3.51.2"},"reference-count":8,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020415","name":"Additional Ventures LLC","doi-asserted-by":"publisher","award":["SVRF1289118"],"award-info":[{"award-number":["SVRF1289118"]}],"id":[{"id":"10.13039\/100020415","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["HL155282"],"award-info":[{"award-number":["HL155282"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015891","name":"Animal Health Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015891","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association Inc","doi-asserted-by":"publisher","award":["23IPA1046350"],"award-info":[{"award-number":["23IPA1046350"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association Inc","doi-asserted-by":"publisher","award":["24TPA1288584"],"award-info":[{"award-number":["24TPA1288584"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association Inc","doi-asserted-by":"publisher","award":["24AVCSASV1277994"],"award-info":[{"award-number":["24AVCSASV1277994"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association Inc","doi-asserted-by":"publisher","award":["24POST1194909"],"award-info":[{"award-number":["24POST1194909"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.scr.2025.103751","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T12:28:17Z","timestamp":1748953697000},"page":"103751","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Characterization of an induced pluripotent stem cell line (NCHi024-A) from a male infant with bicuspid aortic valve"],"prefix":"10.1016","volume":"87","author":[{"given":"Jiyoon","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meghan","family":"Hanley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiqiao","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Argall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Tao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.scr.2025.103751_b0005","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"issue":"9","key":"10.1016\/j.scr.2025.103751_b0010","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.cpcardiol.2005.06.002","article-title":"The bicuspid aortic valve","volume":"30","author":"Braverman","year":"2005","journal-title":"Curr. Probl. Cardiol."},{"issue":"24","key":"10.1016\/j.scr.2025.103751_b0015","doi-asserted-by":"crossref","first-page":"e334","DOI":"10.1161\/CIR.0000000000001106","article-title":"2022 ACC\/AHA guideline for the diagnosis and Management of Aortic Disease: a report of the American Heart Association\/American College of Cardiology Joint Committee on clinical Practice guidelines","volume":"146","author":"Isselbacher","year":"2022","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.scr.2025.103751_b0020","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.jtcvs.2012.11.004","article-title":"Long-term prognosis of ascending aortic aneurysm after aortic valve replacement for bicuspid versus tricuspid aortic valve stenosis","volume":"147","author":"Girdauskas","year":"2014","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"1 Suppl","key":"10.1016\/j.scr.2025.103751_b0025","first-page":"I610","article-title":"Repair of bicuspid aortic valves in patients with aortic regurgitation","volume":"114","author":"El Khoury","year":"2006","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.scr.2025.103751_b0030","first-page":"371","article-title":"Aortic stenosis: diagnosis and treatment","volume":"93","author":"Grimard","year":"2016","journal-title":"Am. Fam. Physician"},{"issue":"5","key":"10.1016\/j.scr.2025.103751_b0035","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/ncpcardio1179","article-title":"Aortic regurgitation: disease progression and management","volume":"5","author":"Goldbarg","year":"2008","journal-title":"Nat. Clin. Pract. Cardiovasc. Med."},{"key":"10.1016\/j.scr.2025.103751_b0040","article-title":"Generation and expansion of human Cardiomyocytes from patient peripheral blood Mononuclear cells","volume":"168","author":"Ye","year":"2021","journal-title":"J. vis. Exp."}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506125001011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506125001011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T07:31:38Z","timestamp":1776843098000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506125001011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":8,"alternative-id":["S1873506125001011"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2025.103751","relation":{},"ISSN":["1873-5061"],"issn-type":[{"value":"1873-5061","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of an induced pluripotent stem cell line (NCHi024-A) from a male infant with bicuspid aortic valve","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2025.103751","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103751"}}