{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T05:40:23Z","timestamp":1792474823400,"version":"4.5.0"},"reference-count":5,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["5254031"],"award-info":[{"award-number":["5254031"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31700898"],"award-info":[{"award-number":["31700898"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Stem Cell Research"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.scr.2026.104119","type":"journal-article","created":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T22:11:47Z","timestamp":1791756707000},"page":"104119","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Generation of a human induced pluripotent stem cell line, PKUHSCi001-A, from a patient with infantile epileptic spasms syndrome carrying a de novo PHF21A variant"],"prefix":"10.1016","volume":"97","author":[{"given":"Yaming","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.scr.2026.104119_b0005","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.seizure.2023.08.009","article-title":"De novo variants in PHF21A cause intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures: a case report and literature review","volume":"111","author":"Chen","year":"2023","journal-title":"Seizure"},{"key":"10.1016\/j.scr.2026.104119_b0010","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s10571-025-01584-8","article-title":"Molecular consequences of a missense PHF21A variant, c.1285G > A, associated with syndromic neurodevelopmental disorder","volume":"45","author":"Gavilan","year":"2025","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.scr.2026.104119_b0015","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13229-019-0286-0","article-title":"Disruption of PHF21A causes syndromic intellectual disability with craniofacial anomalies, epilepsy, hypotonia, and neurobehavioral problems including autism","volume":"10","author":"Kim","year":"2019","journal-title":"Mol. Autism"},{"key":"10.1016\/j.scr.2026.104119_b0020","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1038\/nature06034","article-title":"Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression","volume":"448","author":"Lan","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.scr.2026.104119_b0025","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/MCD.0000000000000455","article-title":"The PHF21A neurodevelopmental disorder: an evaluation of clinical data from 13 patients","volume":"32","author":"Poole","year":"2023","journal-title":"Clin. Dysmorphol."}],"container-title":["Stem Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506126002151?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1873506126002151?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T05:20:43Z","timestamp":1792473643000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1873506126002151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":5,"alternative-id":["S1873506126002151"],"URL":"https:\/\/doi.org\/10.1016\/j.scr.2026.104119","relation":{},"ISSN":["1873-5061"],"issn-type":[{"value":"1873-5061","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Generation of a human induced pluripotent stem cell line, PKUHSCi001-A, from a patient with infantile epileptic spasms syndrome carrying a de novo PHF21A variant","name":"articletitle","label":"Article Title"},{"value":"Stem Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2026.104119","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104119"}}