{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T18:28:28Z","timestamp":1789410508102,"version":"build-2803163510"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T00:00:00Z","timestamp":1656028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Saudi Dental Journal"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.sdentj.2022.06.009","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T01:16:05Z","timestamp":1656465365000},"page":"464-472","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["The effect of Rutin hydrate on Glucocorticoids induced osteoporosis in mandibular alveolar bone in Albino rats (Radiological, histological and histochemical study)"],"prefix":"10.1007","volume":"34","author":[{"given":"Nuha","family":"Abdul-Fattah Baraka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naglaa","family":"Fathallah Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safaa","family":"Ismail Hussein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"10.1016\/j.sdentj.2022.06.009_b0005","doi-asserted-by":"crossref","first-page":"65","DOI":"10.21608\/adjalexu.2019.63560","article-title":"Effect of bisphosphonates on the alveolar bone of rats with glucocorticoids induced osteoporosis","volume":"44","author":"Abdel Fattah","year":"2019","journal-title":"Alexandria Dental J."},{"key":"10.1016\/j.sdentj.2022.06.009_b0010","first-page":"657","article-title":"New approaches to pharmacological treatment of Osteoporosis","volume":"81","author":"Akesson","year":"2003","journal-title":"Bull. World Health Organ."},{"issue":"3","key":"10.1016\/j.sdentj.2022.06.009_b0015","first-page":"445","article-title":"Protective Effects of Rutin on Acute Lung Injury Induced by Oleic Acid in Rats","volume":"23","author":"Aktas","year":"2017","journal-title":"Kfkas univ vet fak derg."},{"key":"10.1016\/j.sdentj.2022.06.009_b0020","series-title":"Connective Tissues and Stains in Theory and Practice of Histological Techniques","first-page":"135","author":"Bancroft","year":"2008"},{"key":"10.1016\/j.sdentj.2022.06.009_b0025","series-title":"Bancroft\u2019s theory and practice of histological techniques","author":"Bancroft","year":"2013"},{"issue":"10","key":"10.1016\/j.sdentj.2022.06.009_b0030","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1007\/s00198-007-0394-0","article-title":"Glucocorticoid-induced osteoporosis: pathophysiology and therapy","volume":"18","author":"Canalis","year":"2007","journal-title":"Osteoporos. Int."},{"issue":"12","key":"10.1016\/j.sdentj.2022.06.009_b0035","doi-asserted-by":"crossref","first-page":"6559","DOI":"10.3390\/ijms22126559","article-title":"Is the Jaw Bone Micro-Structure Altered in Response to Osteoporosis and Bisphosphonate Treatment? A Micro-CT Analysis","volume":"22","author":"Chatterjee","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.sdentj.2022.06.009_b0040","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/s10067-006-0367-2","article-title":"Biomechanical evaluation in osteoporosis: ovariectomized rat model","volume":"26","author":"Comelekoglu","year":"2007","journal-title":"Clin. Rheumatol."},{"issue":"5","key":"10.1016\/j.sdentj.2022.06.009_b0045","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1139\/cjpp-2012-0190","article-title":"Quercetin prevents experimental glucocorticoid-induced osteoporosis: a comparative study with alendronate","volume":"91","author":"Derakhshanian","year":"2013","journal-title":"Can. J. Physiol. Pharmacol."},{"issue":"7","key":"10.1016\/j.sdentj.2022.06.009_b0050","article-title":"Rutin ameliorates carbon tetrachloride (CCl4)-induced hepatorenal toxicity and hypogonadism in male rats","volume":"29","author":"Elsawy","year":"2019","journal-title":"PeerJ"},{"key":"10.1016\/j.sdentj.2022.06.009_b0055","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jsbmb.2014.09.005","article-title":"Protective effects of necrostatin-1 on glucocorticoid-induced osteoporosis in rats","volume":"144","author":"Feng","year":"2014","journal-title":"J. Steroid. Biochem. Mol. Biol."},{"issue":"7","key":"10.1016\/j.sdentj.2022.06.009_b0060","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.apjtb.2017.06.013","article-title":"The protective effect of rutin and quercetin on 5-FU-induced hepatotoxicity in rats","volume":"7","author":"Gelen","year":"2017","journal-title":"Asian Pacific J. Trop. Biomed."},{"key":"10.1016\/j.sdentj.2022.06.009_b0065","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1359\/jbmr.2000.15.11.2251","article-title":"Rutin inhibits ovariectomy-induced osteopenia in rats","volume":"15","author":"Horcajada-Molteni","year":"2000","journal-title":"J. Bone Miner. Res."},{"issue":"9","key":"10.1016\/j.sdentj.2022.06.009_b0070","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s40618-014-0096-3","article-title":"Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid","volume":"37","author":"Hosseinzadeh","year":"2014","journal-title":"J. Endocrinol. Investigat."},{"key":"10.1016\/j.sdentj.2022.06.009_b0075","doi-asserted-by":"crossref","first-page":"347","DOI":"10.4196\/kjpp.2014.18.4.347","article-title":"Effects of Watercress Containing Rutin and Rutin Alone on the Proliferation and Osteogenic Differentiation of Human Osteoblast-like MG-63 Cells","volume":"18","author":"Hyun","year":"2014","journal-title":"Korean J. Physiol. Pharmacol."},{"key":"10.1016\/j.sdentj.2022.06.009_b0080","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1742-7843.2006.pto_241.x","article-title":"Antihyperglycaemic and Antioxidant Effect of Rutin, a Polyphenolic Flavonoid, in Streptozotocin-Induced Diabetic Wistar Rats","volume":"98","author":"Kamalakkannan","year":"2006","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"10.1016\/j.sdentj.2022.06.009_b0085","doi-asserted-by":"crossref","first-page":"699","DOI":"10.12816\/0033786","article-title":"Histological Effect of Bisphosphonate, Vitamin D and Olive Oil on Glucocorticoid Induced Osteoporosis (Gio) in Albino Rat","volume":"65","author":"Kasem","year":"2016","journal-title":"Egyptian J. Hospital Med."},{"issue":"3","key":"10.1016\/j.sdentj.2022.06.009_b0090","first-page":"203","article-title":"Comparison of the mandibular bone densitometry measurement between normal, osteopenic and osteoporotic postmenopausal women","volume":"10","author":"Khojastehpour","year":"2013","journal-title":"J. Dentistry, Tehran Univ. Med. Sci."},{"key":"10.1016\/j.sdentj.2022.06.009_b0095","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1055\/s-0042-110571","article-title":"Glucocorticoid signaling and bone biology","volume":"48","author":"Komori","year":"2016","journal-title":"Horm. Metab. Res."},{"issue":"1","key":"10.1016\/j.sdentj.2022.06.009_b0100","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3858\/emm.2008.40.1.52","article-title":"Rutin inhibits osteoclast formation by decreasing reactive oxygen species and TNF-\u00e1 by inhibiting activation of NF-KB","volume":"40","author":"Kyung","year":"2008","journal-title":"Exp. Mol. Med."},{"issue":"4","key":"10.1016\/j.sdentj.2022.06.009_b0105","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3340\/jkns.2019.0097","article-title":"Rutin Improves Bone Histomorphometric Values by Reduction of Osteoclastic Activity in Osteoporosis Mouse Model Induced by Bilateral Ovariectomy","volume":"63","author":"Lee","year":"2020","journal-title":"J. Korean Neurosurg. Soc."},{"key":"10.1016\/j.sdentj.2022.06.009_b0110","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1007\/s10735-021-10006-0","article-title":"Prednisolone induces osteocytes apoptosis by promoting Notum expression and inhibiting PI3K\/AKT\/GSK3\u03b2\/\u03b2-catenin pathway","volume":"52","author":"Li","year":"2021","journal-title":"J. Mol. Histol."},{"key":"10.1016\/j.sdentj.2022.06.009_b0115","series-title":"Beneficial effects of citrus flavonoids on cardiovascular and metabolic health","first-page":"5484138","author":"Mahmoud","year":"2019"},{"issue":"2","key":"10.1016\/j.sdentj.2022.06.009_b0120","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1590\/S0004-27302010000200015","article-title":"Bone quality and osteoporosis therapy","volume":"54","author":"Martin","year":"2010","journal-title":"Arq. Bras. Endocrinol. Metab."},{"issue":"8","key":"10.1016\/j.sdentj.2022.06.009_b0125","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.3889\/oamjms.2018.291","article-title":"Effect of Laser Therapy on the Osseointegration of Immediately Loaded Dental Implants in Patients under Vitamin C, Omega-3 and Calcium Therapy","volume":"6","author":"Mikhail","year":"2018","journal-title":"Open Access Maced. J. Med. Sci."},{"issue":"1","key":"10.1016\/j.sdentj.2022.06.009_b0130","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1177\/0194599810390470","article-title":"Medical malpractice and corticosteroid use","volume":"144","author":"Nash","year":"2011","journal-title":"Otolaryngol. Head Neck Surg."},{"issue":"1","key":"10.1016\/j.sdentj.2022.06.009_b0135","first-page":"20","article-title":"The In-Vivo Effects of Caffeine and Rutin Combination on Caffeine Intoxication in Rodent Model","volume":"1","author":"Nema","year":"2017","journal-title":"Acta Sci. Pharm. Sci."},{"issue":"7","key":"10.1016\/j.sdentj.2022.06.009_b0140","doi-asserted-by":"crossref","first-page":"20130366","DOI":"10.1259\/dmfr.20130366","article-title":"Digital orthopantomograms in osteoporosis detection: mandibular density and mandibular radiographic indices as skeletal BMD predictors","volume":"43","author":"Pavicin","year":"2014","journal-title":"Dentomaxillofac. Radiol."},{"issue":"3","key":"10.1016\/j.sdentj.2022.06.009_b0145","doi-asserted-by":"crossref","first-page":"212","DOI":"10.4103\/tcmj.tcmj_233_20","article-title":"The molecular etiology and treatment of glucocorticoid-induced osteoporosis","volume":"33","author":"Peng","year":"2021","journal-title":"Tzu Chi. Med. J."},{"key":"10.1016\/j.sdentj.2022.06.009_b0150","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1053\/joca.1998.0230","article-title":"Prostaglandins and bone: physiology and pathophysiology","volume":"7","author":"Raisz","year":"1999","journal-title":"Osteoarthr. Cartilage."},{"issue":"1","key":"10.1016\/j.sdentj.2022.06.009_b0155","doi-asserted-by":"crossref","DOI":"10.4161\/biom.27993","article-title":"Comprehensive histological evaluation of bone implants","volume":"4","author":"Rentsch","year":"2014","journal-title":"Biomatter."},{"issue":"10","key":"10.1016\/j.sdentj.2022.06.009_b0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0258254","article-title":"The cross-talk between matrix metalloproteinase-9, RANKL\/OPG system and cardiovascular risk factors in ovariectomized rat model of postmenopausal osteoporosis","volume":"16","author":"Sabry","year":"2021","journal-title":"PLoS ONE"},{"key":"10.1016\/j.sdentj.2022.06.009_b0165","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00198-003-1548-3","article-title":"Oral glucocorticoid use is associated with an increased risk of fracture","volume":"15","author":"Steinbuch","year":"2004","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.sdentj.2022.06.009_b0170","first-page":"1911","article-title":"Rutin prevents the ovariectomy-induced osteoporosis in rats","volume":"21","author":"Wang","year":"2017","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.sdentj.2022.06.009_b0175","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/os.12369","article-title":"Role of Teriparatide in Glucocorticoid-induced Osteoporosis through Regulating Cellular Reactive Oxygen Species","volume":"10","author":"Wang","year":"2018","journal-title":"Orthop. Surg."},{"key":"10.1016\/j.sdentj.2022.06.009_b0180","unstructured":"Watanabe, P.C., Rodrigues, G. A., Azenha, M. R., Ribeiro, M.C., Filho, E.D.S., Vieira, R.A., Bottacin, F.S., 2021. Bone Quality of the Dento-Maxillofacial Complex and Osteoporosis. Opportunistic Radiographic Interpretation. In: Osteoporosis-Recent Advances, New Perspectives and Applications. Mar 12. IntechOpen. 96487."},{"issue":"3","key":"10.1016\/j.sdentj.2022.06.009_b0185","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.ecl.2012.04.004","article-title":"Glucocorticoid-induced osteoporosis and osteonecrosis","volume":"41","author":"Weinstein","year":"2012","journal-title":"Endocrinol. Metab. Clin. North Am."}],"container-title":["The Saudi Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1013905222000888?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1013905222000888?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T17:28:51Z","timestamp":1736184531000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1013905222000888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S1013905222000888"],"URL":"https:\/\/doi.org\/10.1016\/j.sdentj.2022.06.009","relation":{},"ISSN":["1013-9052"],"issn-type":[{"value":"1013-9052","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of Rutin hydrate on Glucocorticoids induced osteoporosis in mandibular alveolar bone in Albino rats (Radiological, histological and histochemical study)","name":"articletitle","label":"Article Title"},{"value":"The Saudi Dental Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sdentj.2022.06.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.","name":"copyright","label":"Copyright"}]}}