{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:42:21Z","timestamp":1792597341019,"version":"4.5.0"},"reference-count":71,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T00:00:00Z","timestamp":1690761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Saudi Dental Journal"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.sdentj.2023.07.021","type":"journal-article","created":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T02:10:12Z","timestamp":1691201412000},"page":"985-995","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Antitumoral properties of the pomegranate peel and blueberry extracts against tongue carcinoma (in vitro study)"],"prefix":"10.1007","volume":"35","author":[{"given":"Reham Mostafa","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doaa A.M.","family":"Esmaeil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shrief Youssef","family":"El-Nagdy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia Abbas","family":"El-Sisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"issue":"9","key":"10.1016\/j.sdentj.2023.07.021_b0005","doi-asserted-by":"crossref","first-page":"3594","DOI":"10.1158\/0008-5472.CAN-09-3565","article-title":"Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway chemopreventive effects of blueberry phytochemicals","volume":"70","author":"Adams","year":"2010","journal-title":"CancerResearch"},{"issue":"1","key":"10.1016\/j.sdentj.2023.07.021_b0010","first-page":"102","article-title":"Gene expression changes in pomegranate peel extract-treated triple-negative breast cancer cells","volume":"7","author":"Ahmadiankia","year":"2018","journal-title":"Rep. Biochem. Mol. Biol."},{"issue":"1","key":"10.1016\/j.sdentj.2023.07.021_b0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-13357-5","article-title":"Cytotoxicity of thymoquinone alone or in combination with cisplatin (CDDP) against oral squamous cell carcinoma in vitro","volume":"7","author":"Alaufi","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.sdentj.2023.07.021_b0020","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.toxlet.2018.04.008","article-title":"Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells","volume":"291","author":"Allam","year":"2018","journal-title":"Toxicol. Lett."},{"issue":"3","key":"10.1016\/j.sdentj.2023.07.021_b0025","doi-asserted-by":"crossref","first-page":"162","DOI":"10.15430\/JCP.2021.26.3.162","article-title":"miRNA-200b signature in the prevention of skin cancer stem cells by polyphenol-enriched blueberry preparation","volume":"26","author":"Alsadi","year":"2021","journal-title":"J. Cancer Prevent."},{"issue":"7","key":"10.1016\/j.sdentj.2023.07.021_b0030","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-027661","article-title":"Economic burden of managing oral cancer patients in Sri Lanka: A cross-sectional hospital-based costing study","volume":"9","author":"Amarasinghe","year":"2019","journal-title":"BMJ Open"},{"key":"10.1016\/j.sdentj.2023.07.021_b0035","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jnutbio.2016.06.002","article-title":"Blueberry inhibits invasion and angiogenesis in 7, 12-dimethylbenz [a] anthracene (DMBA)-induced oral squamous cell carcinogenesis in hamsters via suppression of TGF-\u03b2 and NF-\u03baB signaling pathways","volume":"35","author":"Baba","year":"2016","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.sdentj.2023.07.021_b0040","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.2147\/IJN.S154033","article-title":"Pomegranate extract-loaded solid lipid nanoparticles: design, optimization, and in vitro cytotoxicity study","volume":"13","author":"Badawi","year":"2018","journal-title":"Int. J. Nanomed."},{"issue":"7","key":"10.1016\/j.sdentj.2023.07.021_b0045","doi-asserted-by":"crossref","first-page":"86","DOI":"10.14715\/cmb\/2018.64.7.15","article-title":"Pomegranate peel extract inhibits expression of \u03b2-catenin, epithelial mesenchymal transition, and metastasis in triple negative breast cancer cells","volume":"64","author":"Bagheri","year":"2018","journal-title":"Cell. Mol. Biol."},{"issue":"4","key":"10.1016\/j.sdentj.2023.07.021_b0050","doi-asserted-by":"crossref","first-page":"179","DOI":"10.36348\/sjmps.2021.v07i04.003","article-title":"Lifestyle diseases: The link between modern lifestyle and threat to public health","volume":"7","author":"Balwan","year":"2021","journal-title":"Saudi J. Med. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.sdentj.2023.07.021_b0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-30046-z","article-title":"Thymoquinone synergizes gemcitabine anti-breast cancer activity via modulating its apoptotic and autophagic activities","volume":"8","author":"Bashmail","year":"2018","journal-title":"Sci. Rep."},{"issue":"8","key":"10.1016\/j.sdentj.2023.07.021_b0060","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.3390\/nu13082733","article-title":"Punicalagin in cancer prevention\u2014via signaling pathways targeting","volume":"13","author":"Berdowska","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.sdentj.2023.07.021_b0065","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s11130-019-00776-0","article-title":"Pomegranate juice and peel extracts are able to inhibit proliferation, migration and colony formation of prostate cancer cell lines and modulate the Akt\/mTOR\/S6K signaling pathway","volume":"75","author":"Chaves","year":"2020","journal-title":"Plant Foods Hum. Nutr."},{"issue":"27","key":"10.1016\/j.sdentj.2023.07.021_b0070","doi-asserted-by":"crossref","first-page":"7054","DOI":"10.1021\/acs.jafc.8b02458","article-title":"Ellagitannins from pomegranate ameliorates 5-fluorouracil-induced intestinal mucositis in rats while enhancing its chemotoxicity against HT-29 colorectal cancer cells through intrinsic apoptosis induction","volume":"66","author":"Chen","year":"2018","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.sdentj.2023.07.021_b0075","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.3389\/fphar.2019.01614","article-title":"Phytochemicals in cancer treatment: From preclinical studies to clinical practice [10.3389\/fphar.2019.01614]","volume":"10","author":"Choudhari","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.sdentj.2023.07.021_b0080","doi-asserted-by":"crossref","first-page":"150","DOI":"10.36347\/sjams.2022.v10i01.025","article-title":"Effect of malvidin on induction of apoptosis and inhibition of cell proliferation on myeloid and lymphoid leukemia","volume":"1","author":"Dahlawi","year":"2022","journal-title":"Sch. J. Appl. Med. Sci."},{"issue":"2","key":"10.1016\/j.sdentj.2023.07.021_b0085","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4103\/0253-7613.93853","article-title":"Antidiabetic and antihyperlipidemic effects of ethanolic extract of leaves of Punica granatum in alloxan-induced non\u2013insulin-dependent diabetes mellitus albino rats","volume":"44","author":"Das","year":"2012","journal-title":"J. Indian J. Pharmacol."},{"issue":"4","key":"10.1016\/j.sdentj.2023.07.021_b0090","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s12253-017-0376-2","article-title":"Beyond conventional medicine-a look at blueberry, a cancer-fighting superfruit","volume":"24","author":"Davidson","year":"2018","journal-title":"Pathol. Oncol. Res."},{"key":"10.1016\/j.sdentj.2023.07.021_b0095","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.biopha.2017.07.008","article-title":"The extract from Punica granatum (pomegranate) peel induces apoptosis and impairs metastasis in prostate cancer cells","volume":"93","author":"Deng","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"2","key":"10.1016\/j.sdentj.2023.07.021_b0100","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.3390\/ijms16022352","article-title":"Antiproliferative and antioxidant properties of anthocyanin rich extracts from blueberry and blackcurrant juice","volume":"16","author":"Diaconeasa","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.sdentj.2023.07.021_b0105","series-title":"Role of Ceramide-1 Phosphate in Regulation of Sphingolipid and Eicosanoid Metabolism in Lung Epithelial Cells","author":"Dudley","year":"2020"},{"issue":"6","key":"10.1016\/j.sdentj.2023.07.021_b0110","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1080\/01635581.2016.1192205","article-title":"Effect of pomegranate hull extract on liver neoplastic changes in rats: more than an antioxidant","volume":"68","author":"El-Ashmawy","year":"2016","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.sdentj.2023.07.021_b0115","doi-asserted-by":"crossref","DOI":"10.1177\/15347354221151021","article-title":"Pomegranate peel extract sensitizes hepatocellular carcinoma cells to ionizing radiation, induces apoptosis and inhibits MAPK, JAK\/STAT3, \u03b2-catenin\/NOTCH, and SOCS3 signaling","volume":"22","author":"Elbakry","year":"2023","journal-title":"Integr. Cancer Therap."},{"issue":"5","key":"10.1016\/j.sdentj.2023.07.021_b0120","doi-asserted-by":"crossref","first-page":"C707","DOI":"10.1111\/j.1750-3841.2011.02179.x","article-title":"Antioxidant capacities of phenolic compounds and tocopherols from Tunisian pomegranate (Punica granatum) fruits","volume":"76","author":"Elfalleh","year":"2011","journal-title":"J. Food Sci."},{"issue":"12","key":"10.1016\/j.sdentj.2023.07.021_b0125","doi-asserted-by":"crossref","first-page":"6618","DOI":"10.1039\/C8FO01394B","article-title":"Finding solutions for agricultural wastes: Antioxidant and antitumor properties of pomegranate Akko peel extracts and \u03b2-glucan recovery","volume":"9","author":"Fazio","year":"2018","journal-title":"Food Funct."},{"issue":"1","key":"10.1016\/j.sdentj.2023.07.021_b0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-36089-6","article-title":"Bioactive glycoalkaloides isolated from Solanum melongena fruit peels with potential anticancer properties against hepatocellular carcinoma cells","volume":"9","author":"Fekry","year":"2019","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.sdentj.2023.07.021_b0135","article-title":"Punicalin and ellagic acid from pomegranate peel extract facilitate apoptotic behaviour in the Hela cell line","volume":"34","author":"Gonzalez-Castillo","year":"2021","journal-title":"Pak. J. Pharm. Sci."},{"issue":"6","key":"10.1016\/j.sdentj.2023.07.021_b0140","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1016\/j.biotechadv.2018.02.011","article-title":"The functional genomic studies of resveratrol in respect to its anti-cancer effects","volume":"36","author":"Huminiecki","year":"2018","journal-title":"J. Biotechnol. Adv."},{"issue":"4","key":"10.1016\/j.sdentj.2023.07.021_b0145","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1111\/cas.15277","article-title":"Inhibition of adult T-cell leukemia cell proliferation by polymerized proanthocyanidin from blueberry leaves through JAK proteolysis","volume":"113","author":"Ichikawa","year":"2022","journal-title":"Cancer Sci."},{"issue":"6","key":"10.1016\/j.sdentj.2023.07.021_b0150","first-page":"128","article-title":"Graviola: A systematic review on its anticancer properties","volume":"3","author":"Ioannis","year":"2015","journal-title":"J. Am. J. Cancer Prevent."},{"issue":"5","key":"10.1016\/j.sdentj.2023.07.021_b0155","doi-asserted-by":"crossref","first-page":"440","DOI":"10.4161\/cam.36224","article-title":"An introduction to the wound healing assay using live-cell microscopy","volume":"8","author":"Jonkman","year":"2014","journal-title":"Cell Adh. Migr."},{"issue":"8","key":"10.1016\/j.sdentj.2023.07.021_b0160","first-page":"358","article-title":"Comparison of polyphenol content and antioxidant capacity of colored potato tubers, pomegranate and blueberries","volume":"5","author":"Kalita","year":"2014","journal-title":"J. Food Process. Technol."},{"issue":"17","key":"10.1016\/j.sdentj.2023.07.021_b0165","doi-asserted-by":"crossref","first-page":"7818","DOI":"10.3390\/app11177818","article-title":"An epidemiological study report on the antioxidant and phenolic content of selected mediterranean functional foods, their consumption association with the Body Mass Index, and consumers purchasing behavior in a sample of healthy Greek adults","volume":"11","author":"Kandyliari","year":"2021","journal-title":"Appl. Sci."},{"issue":"5","key":"10.1016\/j.sdentj.2023.07.021_b0170","doi-asserted-by":"crossref","first-page":"326","DOI":"10.25135\/rnp.170.19.11.1477","article-title":"Pomegranate (Punica granatum L.) Peel Extract: potential cytotoxic agent against different cancer cell lines","volume":"14","author":"Keta","year":"2020","journal-title":"Rec. Nat. Prod."},{"key":"10.1016\/j.sdentj.2023.07.021_b0175","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.phrs.2018.04.021","article-title":"Possible use of Punica granatum (Pomegranate) in cancer therapy","volume":"133","author":"Khwairakpam","year":"2018","journal-title":"J. Pharmacol. Res."},{"key":"10.1016\/j.sdentj.2023.07.021_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2019.125343","article-title":"Blueberry pectin and increased anthocyanins stability under in vitro digestion","volume":"302","author":"Koh","year":"2020","journal-title":"Food Chem."},{"issue":"2","key":"10.1016\/j.sdentj.2023.07.021_b0185","doi-asserted-by":"crossref","first-page":"101","DOI":"10.32471\/exp-oncology.2312-8852.vol-42-no-2.14766","article-title":"Anti-proliferative effects of a blueberry extract on a panel of tumor cell lines of different origin","volume":"42","author":"Lamdan","year":"2020","journal-title":"J. Exp. Oncol."},{"issue":"8","key":"10.1016\/j.sdentj.2023.07.021_b0190","doi-asserted-by":"crossref","first-page":"7475","DOI":"10.1007\/s13277-014-1983-0","article-title":"A polysaccharide from pomegranate peels induces the apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway","volume":"35","author":"Li","year":"2014","journal-title":"Tumor Biol."},{"issue":"8","key":"10.1016\/j.sdentj.2023.07.021_b0195","doi-asserted-by":"crossref","first-page":"e105146","DOI":"10.1371\/journal.pone.0105146","article-title":"Antioxidant and antiproliferative activities of twenty-four Vitis vinifera grapes","volume":"9","author":"Liang","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.sdentj.2023.07.021_b0200","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.fshw.2020.02.004","article-title":"Malvidin-3-galactoside from blueberry suppresses the growth and metastasis potential of hepatocellular carcinoma cell Huh-7 by regulating apoptosis and metastases pathways","volume":"9","author":"Lin","year":"2020","journal-title":"Food Sci. Human Wellness"},{"issue":"6","key":"10.1016\/j.sdentj.2023.07.021_b0205","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbab260","article-title":"oncoPredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data","volume":"22","author":"Maeser","year":"2021","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.sdentj.2023.07.021_b0210","series-title":"Epidermal Cells","first-page":"147","article-title":"In vitro wound healing assays to investigate epidermal migration","author":"Main","year":"2019"},{"key":"10.1016\/j.sdentj.2023.07.021_b0215","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12032-020-01447-w","article-title":"Steps in metastasis: an updated review","volume":"38","author":"Majidpoor","year":"2021","journal-title":"Med. Oncol."},{"issue":"4","key":"10.1016\/j.sdentj.2023.07.021_b0220","first-page":"6116","article-title":"Capsaicin inhibits glycolysis in esophageal squamous cell carcinoma by regulating hexokinase-2 expression","volume":"17","author":"Mao","year":"2018","journal-title":"J. Mol. Med. Rep."},{"key":"10.1016\/j.sdentj.2023.07.021_b0225","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jep.2017.01.030","article-title":"New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines","volume":"198","author":"Mohamed","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.sdentj.2023.07.021_b0230","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/02648725.2022.2122299","article-title":"Recent advances in pomegranate peel extract mediated nanoparticles for clinical and biomedical applications","author":"Monika","year":"2022","journal-title":"Biotechnol. Genet. Eng. Rev."},{"key":"10.1016\/j.sdentj.2023.07.021_b0235","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.foodchem.2018.04.047","article-title":"Phytochemical and physical properties of blueberries, tart cherries, strawberries, and cranberries as affected by different drying methods","volume":"262","author":"Nemzer","year":"2018","journal-title":"Food Chem."},{"issue":"19","key":"10.1016\/j.sdentj.2023.07.021_b0240","doi-asserted-by":"crossref","first-page":"10842","DOI":"10.1039\/C9RA01772K","article-title":"Stability of blueberry anthocyanin, anthocyanidin and pyranoanthocyanidin pigments and their inhibitory effects and mechanisms in human cervical cancer HeLa cells","volume":"9","author":"Pan","year":"2019","journal-title":"RSC Adv."},{"issue":"6","key":"10.1016\/j.sdentj.2023.07.021_b0245","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/tox.22903","article-title":"Pomegranate extract inhibits migration and invasion of oral cancer cells by downregulating matrix metalloproteinase-2\/9 and epithelial-mesenchymal transition","volume":"35","author":"Peng","year":"2020","journal-title":"Environ. Toxicol."},{"issue":"7","key":"10.1016\/j.sdentj.2023.07.021_b0250","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.3390\/antiox10071117","article-title":"Pomegranate extract (POMx) induces mitochondrial dysfunction and apoptosis of oral cancer cells","volume":"10","author":"Peng","year":"2021","journal-title":"Antioxidants"},{"issue":"24","key":"10.1016\/j.sdentj.2023.07.021_b0255","doi-asserted-by":"crossref","first-page":"5916","DOI":"10.3390\/molecules25245916","article-title":"Assessment of the biological activity and phenolic composition of ethanol extracts of pomegranate (Punica granatum L.) peels","volume":"25","author":"Per\u0161uri\u0107","year":"2020","journal-title":"Molecules"},{"issue":"7","key":"10.1016\/j.sdentj.2023.07.021_b0260","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.joms.2019.01.024","article-title":"Oral cancer treatment through the ages: Part 2","volume":"77","author":"Petrosyan","year":"2019","journal-title":"J. Oral Maxillofac. Surg."},{"key":"10.1016\/j.sdentj.2023.07.021_b0265","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3389\/fcell.2019.00107","article-title":"In vitro cell migration, invasion, and adhesion assays: from cell imaging to data analysis","volume":"7","author":"Pijuan","year":"2019","journal-title":"Front. Cell Dev. Biol."},{"issue":"5","key":"10.1016\/j.sdentj.2023.07.021_b0270","doi-asserted-by":"crossref","DOI":"10.5530\/pj.2017.5.109","article-title":"Active constituents of pomegranates (Punica granatum) as potential candidates in the management of health through modulation of biological activities","volume":"9","author":"Rahmani","year":"2017","journal-title":"Pharmacognosy Journal"},{"issue":"7","key":"10.1016\/j.sdentj.2023.07.021_b0275","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.3390\/molecules27072185","article-title":"Anticancer activity of cordia dichotoma against a panel of human cancer cell lines and their phytochemical profiling via HPLC and GCMS","volume":"27","author":"Raina","year":"2022","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.sdentj.2023.07.021_b0280","doi-asserted-by":"crossref","first-page":"567","DOI":"10.3390\/molecules21060567","article-title":"Methyl jasmonate: An alternative for improving the quality and health properties of fresh fruits","volume":"21","author":"Reyes-D\u00edaz","year":"2016","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.sdentj.2023.07.021_b0285","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1080\/15502783.2022.2091412","article-title":"Comparison of the polyphenol content and in vitro antioxidant capacity of fruit-based nutritional supplements commonly consumed by athletic and recreationally active populations","volume":"19","author":"Rickards","year":"2022","journal-title":"J. Int. Soc. Sports Nutr."},{"key":"10.1016\/j.sdentj.2023.07.021_b0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.fitote.2020.104640","article-title":"Plant natural products with anti-thyroid cancer activity","volume":"146","author":"Sharifi-Rad","year":"2020","journal-title":"Fitoterapia"},{"issue":"10","key":"10.1016\/j.sdentj.2023.07.021_b0295","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.3390\/antiox10101600","article-title":"Anthocyanins in colorectal cancer prevention review","volume":"10","author":"Shi","year":"2021","journal-title":"Antioxidants"},{"issue":"13","key":"10.1016\/j.sdentj.2023.07.021_b0300","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/jnci\/82.13.1107","article-title":"New colorimetric cytotoxicity assay for anticancer-drug screening","volume":"82","author":"Skehan","year":"1990","journal-title":"JNCI: J. National Cancer Instit."},{"key":"10.1016\/j.sdentj.2023.07.021_b0305","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.fct.2016.04.020","article-title":"Pomegranate peel extract polyphenols induced apoptosis in human hepatoma cells by mitochondrial pathway","volume":"93","author":"Song","year":"2016","journal-title":"Food Chem. Toxicol."},{"issue":"1","key":"10.1016\/j.sdentj.2023.07.021_b0310","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3390\/antiox12010127","article-title":"Anticancer effect of pomegranate peel polyphenols against cervical cancer","volume":"12","author":"Teniente","year":"2023","journal-title":"Antioxidants"},{"issue":"1","key":"10.1016\/j.sdentj.2023.07.021_b0315","doi-asserted-by":"crossref","DOI":"10.1111\/jfpp.15087","article-title":"\u03b1-Amylase and tyrosinase inhibitory activities, phenolic contents, and antioxidant capacities of wild and cultivated blueberries","volume":"45","author":"Tian","year":"2021","journal-title":"J. Food Process. Preserv."},{"key":"10.1016\/j.sdentj.2023.07.021_b0320","series-title":"Inflammation and Oral Cancer","first-page":"199","article-title":"Chapter 11 - Perspectives in research on oral squamous cell carcinoma","author":"Tomita","year":"2022"},{"key":"10.1016\/j.sdentj.2023.07.021_b0325","series-title":"Plant-derived Bioactives","first-page":"223","article-title":"Pomegranate peel and its anticancer activity: A mechanism-based review","author":"Usha","year":"2020"},{"issue":"4","key":"10.1016\/j.sdentj.2023.07.021_b0330","doi-asserted-by":"crossref","first-page":"436","DOI":"10.3390\/plants9040436","article-title":"The influence of local habitat and microclimate on the levels of secondary metabolites in Slovak bilberry (Vaccinium myrtillus L.) fruits","volume":"9","author":"Vanekov\u00e1","year":"2020","journal-title":"Plants"},{"issue":"2","key":"10.1016\/j.sdentj.2023.07.021_b0335","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1021\/acs.jafc.8b06209","article-title":"Blueberry malvidin-3-galactoside suppresses hepatocellular carcinoma by regulating apoptosis, proliferation, and metastasis pathways in vivo and in vitro","volume":"67","author":"Wang","year":"2018","journal-title":"J. Agric. Food Chem."},{"issue":"1","key":"10.1016\/j.sdentj.2023.07.021_b0340","doi-asserted-by":"crossref","DOI":"10.1080\/16546628.2017.1325308","article-title":"Antiproliferative and proapoptotic activities of anthocyanin and anthocyanidin extracts from blueberry fruits on B16\u2013F10 melanoma cells","volume":"61","author":"Wang","year":"2017","journal-title":"Food Nutr. Res."},{"key":"10.1016\/j.sdentj.2023.07.021_b0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2022.101388","article-title":"Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway","volume":"19","author":"Xie","year":"2022","journal-title":"Transl. Oncol."},{"key":"10.1016\/j.sdentj.2023.07.021_b0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2021.104864","article-title":"Structure and function of blueberry anthocyanins: A review of recent advances","volume":"88","author":"Yang","year":"2022","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.sdentj.2023.07.021_b0355","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.carbpol.2018.09.013","article-title":"Chemical characteristics, antioxidant capacities and hepatoprotection of polysaccharides from pomegranate peel","volume":"202","author":"Zhai","year":"2018","journal-title":"Carbohydr. Polym."}],"container-title":["The Saudi Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1013905223001505?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1013905223001505?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T17:30:06Z","timestamp":1736184606000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1013905223001505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":71,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S1013905223001505"],"URL":"https:\/\/doi.org\/10.1016\/j.sdentj.2023.07.021","relation":{},"ISSN":["1013-9052"],"issn-type":[{"value":"1013-9052","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antitumoral properties of the pomegranate peel and blueberry extracts against tongue carcinoma (in vitro study)","name":"articletitle","label":"Article Title"},{"value":"The Saudi Dental Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sdentj.2023.07.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.","name":"copyright","label":"Copyright"}]}}