{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T02:12:23Z","timestamp":1761012743540,"version":"build-2065373602"},"reference-count":8,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":3186,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seizure-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seizure"],"published-print":{"date-parts":[[2004,12]]},"DOI":"10.1016\/j.seizure.2004.04.018","type":"journal-article","created":{"date-parts":[[2004,7,21]],"date-time":"2004-07-21T14:22:43Z","timestamp":1090419763000},"page":"S11-S15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"S1","title":["Overview of Japanese experience\u2014controlled and uncontrolled trials"],"prefix":"10.1016","volume":"13","author":[{"given":"Kazuichi","family":"Yagi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.seizure.2004.04.018_BIB1","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1021\/jm00188a011","article-title":"Studies on 3-substituted 1,2-benzisoxazole derivatives. VI. Synthesis and their anticonvulsant activities","volume":"22","author":"Uno","year":"1979","journal-title":"J Med Chem"},{"key":"10.1016\/j.seizure.2004.04.018_BIB2","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0006-8993(87)90168-5","article-title":"Zonisamide enhances slow sodium inactivation in Myxicola","volume":"413","author":"Schauf","year":"1987","journal-title":"Brain Res"},{"key":"10.1016\/j.seizure.2004.04.018_BIB3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0920-1211(92)90087-A","article-title":"Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex","volume":"12","author":"Suzuki","year":"1992","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.seizure.2004.04.018_BIB4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S1059-1311(96)80104-X","article-title":"Mechanisms of T-type calcium channel blockade by zonisamide","volume":"5","author":"Kito","year":"1996","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2004.04.018_BIB5","first-page":"439","article-title":"Phase III clinical study of the new antiepileptic drug AD-810, zonisamide, in childhood epilepsy","volume":"41","author":"Oguni","year":"1988","journal-title":"Jpn J Pediatr"},{"key":"10.1016\/j.seizure.2004.04.018_BIB6","first-page":"471","article-title":"Clinical efficacy and safety of a new antiepileptic drug, zonisamide\u2014a multi-institutional phase three study [in Japanese]","volume":"30","author":"Ono","year":"1988","journal-title":"Clin Psychiatry"},{"key":"10.1016\/j.seizure.2004.04.018_BIB7","first-page":"275","article-title":"Efficacy evaluation of AD-810 (zonisamide). Double-blind study comparing with carbamazepine [in Japanese]","volume":"144","author":"Seino","year":"1988","journal-title":"J Clin Exp Med"},{"key":"10.1016\/j.seizure.2004.04.018_BIB8","first-page":"169","article-title":"Zonisamide: new antiepileptic drugs","volume":"3","author":"Seino","year":"1991","journal-title":"Epilepsy Res"}],"container-title":["Seizure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131104000974?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131104000974?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T01:30:37Z","timestamp":1761010237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1059131104000974"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":8,"alternative-id":["S1059131104000974"],"URL":"https:\/\/doi.org\/10.1016\/j.seizure.2004.04.018","relation":{},"ISSN":["1059-1311"],"issn-type":[{"type":"print","value":"1059-1311"}],"subject":[],"published":{"date-parts":[[2004,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Overview of Japanese experience\u2014controlled and uncontrolled trials","name":"articletitle","label":"Article Title"},{"value":"Seizure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.seizure.2004.04.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 BEA Trading Ltd. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}